JPH04261119A - Percutaneous absorption-type pharmaceutical preparation - Google Patents

Percutaneous absorption-type pharmaceutical preparation

Info

Publication number
JPH04261119A
JPH04261119A JP4113091A JP4113091A JPH04261119A JP H04261119 A JPH04261119 A JP H04261119A JP 4113091 A JP4113091 A JP 4113091A JP 4113091 A JP4113091 A JP 4113091A JP H04261119 A JPH04261119 A JP H04261119A
Authority
JP
Grant status
Application
Patent type
Prior art keywords
pts
wt
percutaneous absorption
pharmaceutical preparation
absorbability
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP4113091A
Inventor
Hideaki Okabe
Takanori Saito
Ichiro Tsuchida
Original Assignee
Lintec Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061Polyacrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone

Abstract

PURPOSE: To provide percutaneous absorption-type cataplasm excellent in the percutaneous absorbability for pharmaceutically active substances, good in the stability with the elapse of time of the absorbability because of no crystallization of the substances, also having characteristics such as good adherability.
CONSTITUTION: The objective pharmaceutical preparation with an adhesivity of ≥25g/12mm, comprising a composition which can be obtained by incorporating (A) 100 pts.wt. of a polymer made up of (1) lipophilic monomer unit and (2) hydrophilic monomer unit at the weight ratio (98:2)-(0:100) with (B) pharmaceutically active substance (s), (C) 5-100 pts.wt. of an alcohol, (D) 0-50 pts.wt. of a percutaneous absorption promoter and (E) 0-50 pts.wt. of water.
COPYRIGHT: (C)1992,JPO&Japio
JP4113091A 1991-02-13 1991-02-13 Percutaneous absorption-type pharmaceutical preparation Granted JPH04261119A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP4113091A JPH04261119A (en) 1991-02-13 1991-02-13 Percutaneous absorption-type pharmaceutical preparation
EP19920113659 EP0582727B1 (en) 1991-02-13 1992-08-11 Transdermal therapeutic formulation
US07929044 US5744162A (en) 1991-02-13 1992-08-13 Transdermal therapeutic formulation and a method of administration thereof

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP4113091A JPH04261119A (en) 1991-02-13 1991-02-13 Percutaneous absorption-type pharmaceutical preparation
DE1992618932 DE69218932D1 (en) 1991-02-13 1992-08-11 A transdermal therapeutic formulation
DE1992618932 DE69218932T2 (en) 1991-02-13 1992-08-11 A transdermal therapeutic formulation
EP19920113659 EP0582727B1 (en) 1991-02-13 1992-08-11 Transdermal therapeutic formulation
US07929044 US5744162A (en) 1991-02-13 1992-08-13 Transdermal therapeutic formulation and a method of administration thereof

Publications (1)

Publication Number Publication Date
JPH04261119A true true JPH04261119A (en) 1992-09-17

Family

ID=27234515

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4113091A Granted JPH04261119A (en) 1991-02-13 1991-02-13 Percutaneous absorption-type pharmaceutical preparation

Country Status (4)

Country Link
US (1) US5744162A (en)
EP (1) EP0582727B1 (en)
JP (1) JPH04261119A (en)
DE (2) DE69218932D1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11256126A (en) * 1997-10-28 1999-09-21 Natl Starch & Chem Investment Holding Corp Enhancer tolerant pressure sensitive adhesive for transdermal medicine delivery
JP2009001588A (en) * 1996-10-13 2009-01-08 Neuroderm Ltd Method and equipment for treatment of parkinson's disease

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6190691B1 (en) 1994-04-12 2001-02-20 Adolor Corporation Methods for treating inflammatory conditions
US5962477A (en) 1994-04-12 1999-10-05 Adolor Corporation Screening methods for cytokine inhibitors
WO1996008270A3 (en) * 1994-09-13 1996-05-17 Magainin Pharma Method for inhibiting sexually transmitted diseases using magaining antimicrobials or squalamine compounds
US5714162A (en) * 1994-09-16 1998-02-03 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Scopolamine patch
US5849761A (en) 1995-09-12 1998-12-15 Regents Of The University Of California Peripherally active anti-hyperalgesic opiates
US6573282B1 (en) 1995-09-12 2003-06-03 Adolor Corporation Peripherally active anti-hyperalgesic opiates
JP2001503035A (en) * 1996-10-14 2001-03-06 興和株式会社 External topical anesthetic
DE19649535C2 (en) * 1996-11-29 2000-02-10 Lohmann Therapie Syst Lts A method for producing a plaster-like therapeutic system
US6193996B1 (en) * 1998-04-02 2001-02-27 3M Innovative Properties Company Device for the transdermal delivery of diclofenac
DE19828273B4 (en) * 1998-06-25 2005-02-24 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system containing hormones and crystallization inhibitors
DE10019311A1 (en) * 2000-04-19 2001-10-31 Lohmann Therapie Syst Lts Transdermal therapeutic system used for treating hypertension has reservoir layer based on hydrophilic polymer and/or containing saturated and unsaturated fatty acids
DE10032537A1 (en) * 2000-07-05 2002-01-31 Labtec Gmbh A dermal system containing 2- (3-benzophenyl) propionic acid
US20040092494A9 (en) * 2000-08-30 2004-05-13 Dudley Robert E. Method of increasing testosterone and related steroid concentrations in women
US20040002482A1 (en) * 2000-08-30 2004-01-01 Dudley Robert E. Androgen pharmaceutical composition and method for treating depression
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
DE10049225A1 (en) * 2000-09-28 2002-04-11 Labtec Gmbh Dermal therapeutic system comprises diclofenac sodium in an acrylate copolymer matrix on a polyester web
DE10107663B4 (en) * 2001-02-19 2004-09-09 Lts Lohmann Therapie-Systeme Ag Testosterone-containing transdermal therapeutic system, process for its preparation and its use
DE10224420C1 (en) * 2002-06-01 2003-12-04 Beiersdorf Ag Wet adhesive wound dressing
US20050025833A1 (en) * 2003-07-16 2005-02-03 Chaim Aschkenasy Pharmaceutical composition and method for transdermal drug delivery
US20050020552A1 (en) * 2003-07-16 2005-01-27 Chaim Aschkenasy Pharmaceutical composition and method for transdermal drug delivery
US20050042268A1 (en) * 2003-07-16 2005-02-24 Chaim Aschkenasy Pharmaceutical composition and method for transdermal drug delivery
US20050042182A1 (en) * 2003-08-13 2005-02-24 Moshe Arkin Topical compositions of urea
US20050037040A1 (en) * 2003-08-13 2005-02-17 Moshe Arkin Topical compositions of urea and ammonium lactate
US20050036953A1 (en) * 2003-08-13 2005-02-17 Moshe Arkin Topical compositions of ammonium lactate
CN101415443A (en) * 2003-10-23 2009-04-22 阿尔扎公司 Compositions of stabilized DNA for coating microprojctions
US20070088012A1 (en) * 2005-04-08 2007-04-19 Woun Seo Method of treating or preventing type-2 diabetes
EP1937276B1 (en) 2005-10-12 2012-11-21 Unimed Pharmaceuticals, LLC Improved testosterone gel and method of use
JP5117709B2 (en) * 2006-12-04 2013-01-16 リンテック株式会社 METHOD ultraviolet irradiation apparatus and ultraviolet radiation
CA2738524C (en) 2008-10-02 2013-11-26 Mylan Inc. Method for making a multilayer adhesive laminate
ES2660019T3 (en) 2011-07-20 2018-03-20 Epifarma Srl Patch containing diclofenac and thiocolchicoside

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4291015A (en) * 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator
JPH0314809B2 (en) * 1980-10-20 1991-02-27 Nichiban Kk
CA1184496A (en) * 1980-12-16 1985-03-26 Izhak Blank Nitrogylcerin preparations
JPH0440326B2 (en) * 1984-07-24 1992-07-02 Key Pharma
CA1299319C (en) * 1986-10-23 1992-04-21 Izumi Saitoh Acrylic copolymer and skin protective
US4789547A (en) * 1987-06-17 1988-12-06 Warner-Lambert Company Transdermal matrix system
DE3924393A1 (en) * 1989-07-24 1991-01-31 Roehm Gmbh Water-soluble pressure-sensitive skin contact adhesive whose use and equipped therewith medium

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009001588A (en) * 1996-10-13 2009-01-08 Neuroderm Ltd Method and equipment for treatment of parkinson's disease
JPH11256126A (en) * 1997-10-28 1999-09-21 Natl Starch & Chem Investment Holding Corp Enhancer tolerant pressure sensitive adhesive for transdermal medicine delivery
JP4660830B2 (en) * 1997-10-28 2011-03-30 ヘンケル コーポレイションHenkel Corporation Transdermal drug delivery systems

Also Published As

Publication number Publication date Type
DE69218932T2 (en) 1997-07-17 grant
US5744162A (en) 1998-04-28 grant
EP0582727B1 (en) 1997-04-09 grant
EP0582727A1 (en) 1994-02-16 application
DE69218932D1 (en) 1997-05-15 grant

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