WO2000035952A3 - Compounds for control of eating, growth and body weight - Google Patents

Compounds for control of eating, growth and body weight Download PDF

Info

Publication number
WO2000035952A3
WO2000035952A3 PCT/GB1999/004254 GB9904254W WO0035952A3 WO 2000035952 A3 WO2000035952 A3 WO 2000035952A3 GB 9904254 W GB9904254 W GB 9904254W WO 0035952 A3 WO0035952 A3 WO 0035952A3
Authority
WO
WIPO (PCT)
Prior art keywords
growth
compounds
control
body weight
eating
Prior art date
Application number
PCT/GB1999/004254
Other languages
French (fr)
Other versions
WO2000035952A2 (en
Inventor
Jarl Wikberg
Felikss Mutulis
Ilze Mutule
Helgi Schioeth
Ruta Muceniece
Original Assignee
Melacure Therapeutics Ab
Pett Christopher Phineas
Jarl Wikberg
Felikss Mutulis
Ilze Mutule
Helgi Schioeth
Ruta Muceniece
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Melacure Therapeutics Ab, Pett Christopher Phineas, Jarl Wikberg, Felikss Mutulis, Ilze Mutule, Helgi Schioeth, Ruta Muceniece filed Critical Melacure Therapeutics Ab
Priority to AU17899/00A priority Critical patent/AU1789900A/en
Publication of WO2000035952A2 publication Critical patent/WO2000035952A2/en
Publication of WO2000035952A3 publication Critical patent/WO2000035952A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68—Melanocyte-stimulating hormone [MSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The invention relates to compounds of general formula (1) or general formula (2) and their uses for the treatment of drug abuse, for the control of eating behaviour, body weight and growth and metabolism of animals, including humans.
PCT/GB1999/004254 1998-12-14 1999-12-14 Compounds for control of eating, growth and body weight WO2000035952A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU17899/00A AU1789900A (en) 1998-12-14 1999-12-14 Compounds for control of eating, growth and body weight

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9827500.1A GB9827500D0 (en) 1998-12-14 1998-12-14 Compounds for control of eating, growth and body weight
GB9827500.1 1998-12-14

Publications (2)

Publication Number Publication Date
WO2000035952A2 WO2000035952A2 (en) 2000-06-22
WO2000035952A3 true WO2000035952A3 (en) 2000-10-19

Family

ID=10844193

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1999/004254 WO2000035952A2 (en) 1998-12-14 1999-12-14 Compounds for control of eating, growth and body weight

Country Status (3)

Country Link
AU (1) AU1789900A (en)
GB (1) GB9827500D0 (en)
WO (1) WO2000035952A2 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6716810B1 (en) * 1998-12-09 2004-04-06 Eleanor Roosevelt Institute Composition and method for regulation of body weight and associated conditions
ES2304345T3 (en) 1999-03-29 2008-10-16 THE PROCTER & GAMBLE COMPANY LEGANDOS OF THE RECEIVER OF MELANOCORTINA.
US6693165B2 (en) 2000-01-18 2004-02-17 Merck & Co., Inc. Cyclic peptides as potent and selective melanocortin-4 receptor antagonists
GB0019357D0 (en) 2000-08-07 2000-09-27 Melacure Therapeutics Ab Novel phenyl guanidines
GB0019359D0 (en) 2000-08-07 2000-09-27 Melacure Therapeutics Ab Novel guanidines
US7342089B2 (en) * 2001-07-11 2008-03-11 Palatin Technologies, Inc. Cyclic peptides for treatment for cachexia
EP1441750A4 (en) * 2001-07-11 2006-10-18 Palatin Technologies Inc Linear and cyclic melanocortin receptor-specific peptides
AU2002331064B2 (en) 2001-08-10 2007-08-23 Palatin Technologies, Inc. Peptidomimetics of biologically active metallopeptides
US20030195187A1 (en) * 2002-02-04 2003-10-16 Chiron Corporation Guanidino compounds
AU2004251616A1 (en) * 2003-06-19 2005-01-06 Eli Lilly And Company Melanocortin receptor 4(MC4) agonists and their uses
EP2033662B1 (en) 2004-01-21 2012-10-17 Novo Nordisk Health Care AG Transglutaminase mediated conjugation of peptides
DE102007020152A1 (en) * 2007-04-26 2008-10-30 Charité - Universitätsmedizin Berlin Agent for anti-infective treatment of a patient
MX2010013436A (en) 2008-06-09 2011-06-21 Palatin Technologies Inc Melanocortin receptor-specific peptides for treatment of sexual dysfunction.
UY32690A (en) 2009-06-08 2011-01-31 Astrazeneca Ab SPECIFIC PEPTIDES FOR MELANOCORTIN RECEPTORS
NZ596617A (en) 2009-06-08 2014-04-30 Palatin Technologies Inc Melanocortin receptor-specific peptides
EP2440572B1 (en) 2009-06-08 2017-04-05 Palatin Technologies, Inc. Lactam-bridged melanocortin receptor-specific peptides
WO2011063366A1 (en) 2009-11-23 2011-05-26 Palatin Technologies, Inc. Melanocortin-1 receptor-specific cyclic peptides
CA2781405A1 (en) 2009-11-23 2011-05-26 Palatin Technologies, Inc. Melanocortin-1 receptor-specific linear peptides
RU2020120797A (en) * 2013-03-15 2020-07-02 Ритм Фармасьютикалз, Инк. PEPTIDE COMPOSITIONS

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998010068A2 (en) * 1996-09-04 1998-03-12 Oregon Health Sciences University Methods and reagents for discovering and using mammalian melanocortin receptor agonists and antagonists to modulate feeding behavior in animals
WO1998037097A1 (en) * 1997-02-21 1998-08-27 Wapharm Ab Msh-receptor subtype selective cyclic peptides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998010068A2 (en) * 1996-09-04 1998-03-12 Oregon Health Sciences University Methods and reagents for discovering and using mammalian melanocortin receptor agonists and antagonists to modulate feeding behavior in animals
WO1998037097A1 (en) * 1997-02-21 1998-08-27 Wapharm Ab Msh-receptor subtype selective cyclic peptides

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
FINCH, ANGELA M. ET AL: "Low-Molecular- Weight Peptidic and Cyclic Antagonists of the Receptor for the Complement Factor C5a", J. MED. CHEM. (1999), 42(11), 1965-1974, 3 June 1999 (1999-06-03), XP002137173 *
KASK, ANTS ET AL: "Discovery of a novel superpotent and selective melanocortin-4 receptor antagonist (HS024): evaluation in vitro and in vivo", ENDOCRINOLOGY (1998), 139(12), 5006-5014, 1998, XP002137172 *
SCHIOETH, HELGI B. ET AL: "Binding of cyclic and linear MSH core peptides to the melanocortin receptor subtypes", EUR. J. PHARMACOL. (1997), 319(2/3), 369-373, 1997, XP000906899 *

Also Published As

Publication number Publication date
WO2000035952A2 (en) 2000-06-22
GB9827500D0 (en) 1999-02-10
AU1789900A (en) 2000-07-03

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