WO1995034655A3 - Surface protein of staphylococcus aureus - Google Patents

Surface protein of staphylococcus aureus Download PDF

Info

Publication number
WO1995034655A3
WO1995034655A3 PCT/US1995/007100 US9507100W WO9534655A3 WO 1995034655 A3 WO1995034655 A3 WO 1995034655A3 US 9507100 W US9507100 W US 9507100W WO 9534655 A3 WO9534655 A3 WO 9534655A3
Authority
WO
WIPO (PCT)
Prior art keywords
staphylococcus aureus
surface protein
catheters
staphylococcis
neutralization
Prior art date
Application number
PCT/US1995/007100
Other languages
French (fr)
Other versions
WO1995034655A2 (en
Inventor
Ambrose Cheung
Vincent A Fischetti
Original Assignee
Univ Rockefeller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rockefeller filed Critical Univ Rockefeller
Priority to JP8502282A priority Critical patent/JPH10501418A/en
Priority to EP95922211A priority patent/EP0771351A1/en
Publication of WO1995034655A2 publication Critical patent/WO1995034655A2/en
Publication of WO1995034655A3 publication Critical patent/WO1995034655A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Methods and compositions are provided for preventing Staphylococcus aureus infections associated with the use of catheters and similar devices. They are based on the neutralization of ability of surface proteins of staphylococcis to adhere to the surface of the catheters at the skin-catheter junction as the first step in the systemic invasion of the host by the organism.
PCT/US1995/007100 1994-06-07 1995-06-05 Surface protein of staphylococcus aureus WO1995034655A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP8502282A JPH10501418A (en) 1994-06-07 1995-06-05 Staphylococcus aureus surface protein
EP95922211A EP0771351A1 (en) 1994-06-07 1995-06-05 Surface protein of staphylococcus aureus

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25496894A 1994-06-07 1994-06-07
US08/254,968 1994-06-07

Publications (2)

Publication Number Publication Date
WO1995034655A2 WO1995034655A2 (en) 1995-12-21
WO1995034655A3 true WO1995034655A3 (en) 1996-02-01

Family

ID=22966279

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1995/007100 WO1995034655A2 (en) 1994-06-07 1995-06-05 Surface protein of staphylococcus aureus

Country Status (4)

Country Link
EP (1) EP0771351A1 (en)
JP (1) JPH10501418A (en)
CA (1) CA2192175A1 (en)
WO (1) WO1995034655A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPN350795A0 (en) * 1995-06-13 1995-07-06 Australian National University, The Nucleic acid molecule and its uses in determining pathogenicity of Staphylococcus
WO1999027109A2 (en) * 1997-11-26 1999-06-03 Inhibitex, Inc. EXTRACELLULAR MATRIX-BINDING PROTEINS FROM $i(STAPHYLOCOCCUS AUREUS)
US6680195B1 (en) 1997-11-26 2004-01-20 Inhibitex, Inc. Extracellular matrix-binding proteins from staphylococcus aureus
US6692739B1 (en) * 1998-08-31 2004-02-17 Inhibitex, Inc. Staphylococcal immunotherapeutics via donor selection and donor stimulation
TR201809128T4 (en) 2009-07-15 2018-07-23 Aimm Therapeutics Bv Compounds that bind specifically to gram-positive bacteria.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994006830A1 (en) * 1992-09-21 1994-03-31 Alfa-Laval Agri International Aktiebolag Fibrinogen binding protein

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994006830A1 (en) * 1992-09-21 1994-03-31 Alfa-Laval Agri International Aktiebolag Fibrinogen binding protein

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
A.I. CHEUNG ET AL: "Cloning, expression and nucleotide sequence of a Staphylococcus aureus gene (fbpA) encoding a Fibrinogen-Binding Protein", INFECTION AND IMMUNITY, vol. 63, no. 5, WASHINGTON US, pages 1914 - 1920 *
F. ESPERSEN ET AL: "Isolation of Staphylococcus aureus Clumping factor", INFECTION AND IMMUNITY, vol. 49, no. 3, WASHINGTON US, pages 700 - 708 *
S. KAIDA ET AL: "Nucleotide and deduced amino acid sequence of staphylocoagulase gene from Staphylococcus aureus strain 213", NUCLEIC ACIDS RESEARCH, vol. 17, no. 21, OXFORD GB, pages 8871 *
S. KAIDA ET AL: "Nucleotide sequence of the Staphylocoagulase gene: Its unique COOH-Terminal 8 tandem repeats", JOURNAL OF BIOCHEMISTRY, vol. 102, TOKYO JP, pages 1177 - 1186 *
YUKIO USUI: "Biochemical properties of Fibrinogen binding protein (Clumping Factor) of the Staphylococcal cell surface", ZENTRALBLATT FÜR BAKTERIOLOGIE MIKROBIOLOGIE UND HYGIENE, vol. 262A, pages 287 - 297 *

Also Published As

Publication number Publication date
WO1995034655A2 (en) 1995-12-21
EP0771351A1 (en) 1997-05-07
JPH10501418A (en) 1998-02-10
CA2192175A1 (en) 1995-12-21

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