WO1995027063A3 - Rfb-retrovirusgenom - Google Patents

Rfb-retrovirusgenom Download PDF

Info

Publication number
WO1995027063A3
WO1995027063A3 PCT/EP1995/001234 EP9501234W WO9527063A3 WO 1995027063 A3 WO1995027063 A3 WO 1995027063A3 EP 9501234 W EP9501234 W EP 9501234W WO 9527063 A3 WO9527063 A3 WO 9527063A3
Authority
WO
WIPO (PCT)
Prior art keywords
rfb
retrovirus
genome
retrovirus genome
bone regeneration
Prior art date
Application number
PCT/EP1995/001234
Other languages
English (en)
French (fr)
Other versions
WO1995027063A2 (de
Inventor
Jörg Schmidt
Wolfgang Gimbel
Paul-Günter STRAUSS
Volker Erfle
Finn Skou Pedersen
Lene Pedersen
Mette ØSTERGAARD
Original Assignee
Gsf-Forschungszentrum Für Umwelt Und Gesundheit, Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gsf-Forschungszentrum Für Umwelt Und Gesundheit, Gmbh filed Critical Gsf-Forschungszentrum Für Umwelt Und Gesundheit, Gmbh
Priority to AU23050/95A priority Critical patent/AU2305095A/en
Priority to EP95916604A priority patent/EP0755448A1/de
Publication of WO1995027063A2 publication Critical patent/WO1995027063A2/de
Publication of WO1995027063A3 publication Critical patent/WO1995027063A3/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Erfindungsgemäß wird die vollständige Gensequenz des RFB-Provirusgenoms angegeben. Es wird vorgeschlagen, daß RFB-Retrovirus und andere, damit verwandte osteoinduktive Retroviren zur Entwicklung eines Therapeutikums zur Behandlung von Knochenerkrankungen, insbesondere zur Induktion von Knochenneubildung, einzusetzen. Erfindungsgemäß wurden die codierenden Bereiche des RFB-Retrovirus als die für die Knochenneubildung verantwortlichen Genomabschnitte identifiziert.
PCT/EP1995/001234 1994-04-05 1995-04-05 Rfb-retrovirusgenom WO1995027063A2 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU23050/95A AU2305095A (en) 1994-04-05 1995-04-05 Rfb retrovirus genome
EP95916604A EP0755448A1 (de) 1994-04-05 1995-04-05 Rfb-retrovirusgenom

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP4411718.3 1994-04-05
DE4411718A DE4411718A1 (de) 1994-04-05 1994-04-05 RFB-Retrovirusgenom

Publications (2)

Publication Number Publication Date
WO1995027063A2 WO1995027063A2 (de) 1995-10-12
WO1995027063A3 true WO1995027063A3 (de) 1995-12-14

Family

ID=6514671

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1995/001234 WO1995027063A2 (de) 1994-04-05 1995-04-05 Rfb-retrovirusgenom

Country Status (4)

Country Link
EP (1) EP0755448A1 (de)
AU (1) AU2305095A (de)
DE (1) DE4411718A1 (de)
WO (1) WO1995027063A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4427221A1 (de) * 1994-08-01 1996-02-08 Gsf Forschungszentrum Umwelt Retrovirus-induzierte Osteoklasten-Modulation für die Osteoporose-Therapie

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0572737A2 (de) * 1992-06-04 1993-12-08 The Research Foundation For Microbial Diseases Of Osaka University Gag-Env Fusion-Antigen aus HIV
WO1994005780A1 (en) * 1992-08-28 1994-03-17 The Public Health Research Institute Of The City Of New York, Inc. Fusion glycoproteins

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0572737A2 (de) * 1992-06-04 1993-12-08 The Research Foundation For Microbial Diseases Of Osaka University Gag-Env Fusion-Antigen aus HIV
WO1994005780A1 (en) * 1992-08-28 1994-03-17 The Public Health Research Institute Of The City Of New York, Inc. Fusion glycoproteins

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
A. DUSTY MILLER ET AL.: "Deletion of the gag region from FBR murine osteosarcoma virus does not affect its enhanced transforming activity", JOURNAL OF VIROLOGY, vol. 55, no. 3, pages 521 - 526 *
L. PEDERSEN ET AL.: "Molecular Cloning of Osteoma-Inducing replication Competent Murine Leukemia Viruses from the RFB Osteoma Virus Stock", JOURNAL OF VIROLOGY, vol. 66, no. 10, pages 6186 - 6190 *

Also Published As

Publication number Publication date
AU2305095A (en) 1995-10-23
DE4411718A1 (de) 1995-10-12
WO1995027063A2 (de) 1995-10-12
EP0755448A1 (de) 1997-01-29

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