WO1995021642A1 - Canule hemostatique - Google Patents

Canule hemostatique Download PDF

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Publication number
WO1995021642A1
WO1995021642A1 PCT/US1995/001979 US9501979W WO9521642A1 WO 1995021642 A1 WO1995021642 A1 WO 1995021642A1 US 9501979 W US9501979 W US 9501979W WO 9521642 A1 WO9521642 A1 WO 9521642A1
Authority
WO
WIPO (PCT)
Prior art keywords
valve body
slit
housing
height dimension
recess
Prior art date
Application number
PCT/US1995/001979
Other languages
English (en)
Inventor
Thomas A. Osborne
Ram H. Paul
Original Assignee
Cook Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cook Incorporated filed Critical Cook Incorporated
Priority to AU19667/95A priority Critical patent/AU1966795A/en
Publication of WO1995021642A1 publication Critical patent/WO1995021642A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/06—Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof
    • A61M39/0606—Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof without means for adjusting the seal opening or pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/06—Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof
    • A61M2039/062—Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof used with a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/06—Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof
    • A61M2039/0633—Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof the seal being a passive seal made of a resilient material with or without an opening
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A61M39/06—Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof
    • A61M2039/0633—Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof the seal being a passive seal made of a resilient material with or without an opening
    • A61M2039/064—Slit-valve

Definitions

  • This invention relates to a cannula or sheath and particularly to a cannula useful with angiographic catheters .
  • the angiographer uses the Desilets-Hoffman procedure to do a multiple study. In this procedure, the angiographer obtains access to a patient's blood vessel by inserting a hollow needle through the skin and into the lumen of the blood vessel. A guide wire is passed through the needle and advanced through the artery or vein into the organ to be studied. The needle is removed leaving the guide wire in the organ. A cannula and dilator are advanced over the wire into the vessel and the dilator is removed along the guide wire.
  • the angiographer then conducts the multiple studies by inserting various types of catheters into the vessel through the cannula or sheath.
  • this technique requires occlusion of the passage through the cannula during catheter changes.
  • One method of obtaining the required occlusion is to position a valve body formed from a pliable material in the passageway of the cannula.
  • Such valve bodies are shown for instance in U.S. Patent No. 4,000,739 to Stevens, U.S. Patent No. 4,430,081 to Timmermans, U.S. Patent No. 4,610,665 to Matsumoto et al., U.S. Patent No. 5,006,113 to Fischer and International Publication Number WO 91/10459 to Savage et al.
  • one or more disk-like gaskets are mounted in the cannula passage.
  • the disk-like gaskets or valve bodies include an opening therethrough which is biased to a closed position when no catheter is present in order to prevent an air embolism from occurring by air being drawn into the patient's vein through the cannula.
  • the valve body conforms to the shape of the outer wall of the catheter, thereby preventing blood flow out of the cannula between the catheter and the valve body.
  • One embodiment of the present invention might include a hemostasis cannula comprising a housing having a passage sized to receive a catheter therethrough.
  • a valve body formed from a single piece of pliable material is mounted in the passage of the housing.
  • the valve body includes a slit through one face which extends partly through the valve body and an opening through the opposing face extending only partly through the valve body. Both the slit and the opening extend far enough into the valve body that they intersect within the valve body.
  • a means which contacts a portion of the peripheral edge of the valve body for compressing the valve body in a direction substantially perpendicular to the slit in order to maintain the slit in a fluid-tight seal.
  • the valve body is made of a material which will conform to the shape of the outer wall of a catheter when the catheter penetrates through the slit and opening in the valve body thereby maintaining a fluid-tight seal between the outer wall of the catheter and the valve body.
  • a further embodiment of the present invention might include a hemostasis cannula comprising a housing having a passage sized to receive a catheter therethrough.
  • a valve body similar to the valve body described above, formed from a single piece of pliable material is mounted in the passage of the housing.
  • the valve body includes a slit through one planar face which extends partly through the valve body and an opening through the opposing planar face extending only partly through the valve body. Additionally, a raised ring on the opposing planar face surrounds the opening.
  • Both the slit and the opening extend far enough into the valve body that they intersect within the valve body. Also included is a means which contacts a portion of the peripheral edge of the valve body for compressing the valve body in a direction substantially perpendicular to the slit in order to maintain the slit in a fluid-tight seal.
  • One object of the present invention is to provide an improved hemostasis cannula.
  • Another object of the present invention is to provide a method for making an improved hemostasis cannula.
  • FIG. 1 is a cross-sectional view taken axially of a hemostasis cannula of the present invention.
  • FIG. 2 is an exploded partially cut-away view of the embodiment of FIG. 1.
  • FIG. 3 is a side elevational view of the cannula having a dilator unit and wire guide therein.
  • FIG. 4 is a view similar to FIG. 3 showing the cannula in position in the lumen of a blood vessel with a catheter enclosed therein.
  • FIG. 5 is a front view of the valve body used in the hemostasis cannula of FIGS. 1 and 2.
  • FIG. 6 is a bottom partially cut-away view of the valve body shown in FIG. 5.
  • FIG. 7 is a side view of the valve body shown in FIGS. 5 and 6.
  • FIG. 8 is a view looking axially into the recess portion of the housing of the hemostasis cannula of the present invention showing a front view of the valve body of FIGS. 5-7 before and after it has been compressed and fitted into the recess of the housing.
  • FIG. 9 is a front view of another valve body according to the present invention.
  • FIG. 10 is a front view of the valve body shown in FIG. 9 after being compressed.
  • FIG. 11 is a front view of still another valve body according to the present invention.
  • FIG. 12 is a front view of the valve body shown in FIG. 11 after being compressed.
  • FIG. 13 is a front view of a further embodiment of a valve body used in the hemostasis cannula of FIGS. 1 and 2.
  • FIG. 14 is a bottom partially cut-away view of the valve body shown in FIG. 13.
  • FIG. 15 is a side view of the valve body shown in FIGS, 13 and 14.
  • FIG. 15A is an enlarged view of a portion of the valve body shown in FIGS. 13 - 15.
  • FIGS. 1 and 2 there is illustrated in FIGS. 1 and 2 a hemostasis cannula which includes a housing 10 having a passage 11 therethrough adapted to receive a catheter.
  • Housing 10 is made up of a member 12 having two externally threaded surfaces 15 and 16.
  • a cap 17, which includes recess 18, is threaded down on the member 12 on the threads 15 and is glued in place by a suitable cement or the like.
  • Valve body 1 is received into recess 18 and is sandwiched between cap 17 in member 12.
  • the face 6 including the cylindrical recess or hole 3 of valve body 1 is directed towards the opening 70 of the cap 17.
  • the cannula housing 10 also includes an internally threaded member 32, the threads of which are suitable for mating engagement with the threads 16 on the member 12.
  • the function of the member 32 is to receive and fix or hold the flexible tubing 35 to the housing 10.
  • adhesive or cement is placed on the flexible tubing 35 and between the members 12 and 32 for affixing the tubing and members together.
  • the flexible tubing 35 has a flared end 36 which is fixed between the tapered surfaces 37 and 40 of the members 12 and 32.
  • Housing 10 is provided with a port 45 which communicates with passage 11 between valve body 1 and flexible tube 35 for introducing fluids into the patient's blood vessel.
  • the physician normally maintains a positive pressure of flushing fluid through the flexible tubing 46 (FIGS. 3 and 4), which is attached to the projection 47 by means of the annular ridges 50.
  • the flexible tubing 35 is further secured to housing 10 by means of shrinkable tubing 51 which is secured about collar 52 via the annular ridges 55.
  • a hollow plastic dilator 56 having an outer diameter substantially equal to that of catheter 57 (FIG.
  • the dilator and guide wire may be removed and discarded.
  • Valve body 1 is oblong in shape and has a height dimension II_ which is greater than the height dimension H of recess 18. Therefore, valve body 1 must be compressed in the direction of arrows 8 in order to be received within recess 18.
  • Valve body 1 includes a pair of opposing faces 6 which are separated by a peripheral edge 5.
  • a hole or cylindrical recess 3 is made through one of the faces and extends partially through the valve body as shown in FIG. 1. The hole 3 may be formed by molding during the process of forming the disk or punched, cut or drilled in a separate operation.
  • a slit 2 is made through the other face and extends partially through the valve body intersecting hole 3 within the valve body.
  • Valve body 1 is preferably made from silicon rubber or another elastomer having a durometer hardness anywhere between 20 and 90. Referring to FIGS. 5-8, valve body 1 preferably has an oblong shape such that peripheral edge 5 includes a pair of parallel planar surfaces 4 which are perpendicular to the plane defined by slit 2. Slit 2 preferably extends completely across one of the faces 6 and extends into the valve body to a depth of between 1/3 and 2/3 the thickness of the valve body. Hole 3 preferably has a 5 diameter between 0.010 and 0.035 inches and, like slit 2, has a depth preferably between 1/3 and 2/3 the thickness of valve body 1.
  • valve body 1 has a height dimension H_ which is greater than its width dimension W_ .
  • FIG. 8 shows the valve body 1 both before and after it has been compressed in order to be positioned in 5 recess 18 of housing 10. Before being compressed, valve body 1 has a height dimension H_ which is greater than height dimension III of recess 18 as shown in FIG. 2. So that the compression forces on valve body 1 are directed only perpendicularly to slit 2, valve body 1 has a width dimension 0 w. which is less than the width dimension W, of recess
  • Planar portions 4 allow valve body 1 to expand in its width dimension without interacting with the recess when it is compressed and received within the recess 18.
  • FIGS. 9 and 10 show another embodiment of a valve body 5 101 which can be used with the hemostasis cannula of FIGS. 1 and 2.
  • valve body 101 is oblong in shape and includes a pair of intersecting slits 102 and 103.
  • the slit configuration of the valve body 101 may be as is more completely described in U.S. Patent No. 4,610,665 to 0 Matsumoto et al., which description is incorporated herein by reference.
  • the intersecting slits 102 and 103 may extend completely across the respective faces of valve 101, as is shown in FIGS. 9 and 10 .
  • valve body 101 is 5 compressed along arrows 8 perpendicular to slit 102 so that the valve body may be received within the recess of a cannula housing as described previously.
  • the compression force 8 improves the performance by insuring that slit 102 remains closed during catheter exchanges.
  • FIGS. 11 and 12 illustrate still another embodiment of a valve body according to the present invention.
  • valve body 111 is oblong. in shape similar to the shape discussed in reference to valve body 1 shown in FIGS. 5-8. In this case, however, valve body 111 includes a hole 112 completely through the valve body. Hole 112 includes boundary walls 113 and 114 which remain separate when valve body 11 is uncompressed.
  • valve body 111 When sufficient compression is applied to valve body 111, as shown in FIG. 12, boundary walls 113 and 114 are forced together, thus forming a fluid-tight seal through the valve body.
  • the compression concept of the present invention has application in hemostasis cannulas having two or more valve body gaskets as shown in U.S. Patent No. 4,000,739 to Stevens or U.S. Patent No. 4,430,081 to Timmermans, or to hemostasis cannulas containing a single valve body gasket as shown in U.S. Patent No. 4,610,665 to Matsurnoto et al., and U.S. Patent No. 5,006,113 to Fischer.
  • FIGS. 13-15 ⁇ show yet another embodiment of a valve body according to the present invention.
  • FIG. 13 is a front view of a valve body 1' which is substantially similar to the valve body 1, with the major difference being the addition of a raised ring or doughnut 7' which surrounds the hole 3' .
  • the valve body 1' may be substituted for the valve body 1 in the hemostasis cannula of FIGS. 1 and 2.
  • the face 6' including the cylindrical recess or hole 3' and the raised ring 7' of valve body 1' may be directed towards the opening 70 of the cap 17 (FIGS. 1 and 2).
  • valve body 1' is oblong in shape and has a height dimension H ' which is greater than the height dimension H. of recess 18 of FIG. 1. Therefore, valve body 1' must additionally be compressed in the direction of arrows 8 in order to be received within recess 18.
  • Valve body 1' includes a pair of opposing planar faces 6' which are separated by a peripheral edge 5' .
  • a hole or cylindrical recess 3' is made through one of the faces and extends partially through the valve body as shown in FIG. 14. The hole 3' may be .formed by molding during the process of forming the disk or punched, cut or drilled in a separate operation.
  • a slit 2' is made through the other face and extends partially through the valve body intersecting hole 3' within the valve body. Additionally, a raised ring 7' on the top surface of the valve provides a lead-in to the hole 3' of the valve body 1' . As such, the raised ring 7' makes it easier to place very small diameter devices through the valve. The extra material around the hole 3' additionally makes the valve less likely to tear.
  • valve body 1' (including raised ring 7') is preferably mac3 from silicon rubber or another elastomer having a duro ⁇ ? _er hardness anywhere between 20 and 90.
  • valve body 1' preferably has an oblong shape such that peripheral edge 5" includes a pair of parallel planar surfaces 4' which are perpendicular to the plane defined by slit 2' .
  • Slit 2' preferably extends completely across one of the faces 6' and extends into the valve body to a depth of between 1/3 and 2/3 the thickness of the valve body.
  • the thickness of the valve body 1" may be .062 inches +/- .002 inches and the slit depth may be between .040 and .045 inches.
  • Hole 3' preferably has a diameter of between 0.010 and 0.035 inches and, like slit 2', has a depth preferably between 1/3 and 2/3 the thickness of valve body 1' .
  • the combined depth of hole 3' and slit 2' must be sufficient that they intersect within the valve body and create an opening completely through the valve body for receiving a catheter or the like therethrough.
  • the oblong shape of valve body 1' results in it having a height dimension H ' which is greater than its width dimension W * .
  • height H ' is between .405 and .410 inches in diameter compared to a width W ' of between .340 and ..360 inches.
  • the raised ring 7' is centered around the hole 3' . Additionally, as can be seen more clearly in FIG. 15A, the inner wall 9' of the raised ring 7' is sloped from the top of the raised ring 7' down to the face 6'. An angle ⁇ can be measured between a plane parallel to the face 6' and the inner wall 9' . In the above mentioned particular embodiment angle ⁇ is 45° . Further, in that embodiment, the outer diameter of raised ring 7' is chosen to be between .145 -.155 inches while the inner diameter, measured at the top of the raised ring, may be between .080 -.095 inches in diameter. Additionally, the raised ring may extend between .025 and .030 inches above the face 6 ' .
  • the tapered walls terminate at the surface of the planar face 6' prior to the beginning of the hole 3', thus forming a small planar surface between the hole 3' and the raised ring 7'.
  • the sloping inner wall 9' can terminate directly at the edge of the hole 3' .
  • valve body 1' before being compressed, valve body 1' has a height dimension II ' which is greater than height dimension H, of recess 18 shown in FIGS. 1 and 2. So that the compression forces on valve body 1' are directed only perpendicularly to slit 2*, valve body 1' has a width dimension W ' which is less than the width dimension W ' of recess 18 of FIG. 1. Planar portions 4' allow valve body 1 * to expand in its width dimension without interacting with the recess when it is compressed and received within the recess 18 of FIG. 1.
  • the compression applied to the valve body could be produced by any of a number of methods.
  • valve bodies 1 and 1' both work well with a wide range of device diameters, and because of the compression, the valve body is insensitive to such factors as slit depth and hole diameter.
  • a hollow needle subcutaneously enters the blood vessel.
  • guide wire 61 is threaded into the needle and blood vessel, and the needle is removed.
  • a hollow plastic dilator 60 is then passed through passage 11 of the cannula housing and is slid over guide 61. The physician then dilates the hole through the vessel wall by maneuvering the tapered end 60 of the dilator 56, and introduces the entrance tube 35 into vessel lumen 62.
  • the outer diameter of the dilator at its constant diameter portion is close to the outer diameter of the flexible tubing 35 so that tubing 35 is guided through the wall of the vessel by the dilator.
  • the cannula is then taped into position on the body of the patient.
  • the physician withdraws dilator 56 and guide 61.
  • slit 2 or 2' in valve body 1 or 1' closes.
  • the closure of slit 2 or 2 ' insures that no air passes through the opening 70 of cap 17 and through valve body 1 or 1' into passage 11.
  • the present device not only prevents blood loss but also insures against the possibility of an air embolism.
  • the catheter 57 is then introduced through the opening in cap 17 and passes through valve body 1 or 1' .
  • Catheter 57 is guided through passage 11 and flexible tubing 35 by the tapered surfaces 71 and 72.
  • the catheter finally passes into lumen 62 of the blood vessel.
  • Hole 3 or 3 * (and in the case of valve 1', raised ring 7') forms a seal around the exterior wall of catheter 57 and prevents blood loss through hole 70 in the cap.
  • Passage 11 is constantly flushed by a flow of heparin saline solution introduced through the port 45 and tubing 46 in order to prevent clotting.
  • radiopaque fluid is injected through the catheter and X-ray photographs may be taken of the radiopaque configuration of the organ being studied.
  • the catheter may be easily removed from the cannula housing and replaced with another catheter.
  • a guide wire may be used by passing it through the cannula housing if needed. Because slit 2 or 2' n valve body 1 or 1" closes at the time of removal of the catheter, no bleeding is experienced by the patient and no air is allowed to enter into the patient's blood vessel in the event that the pressure external of the cannula is greater than the pressure within the blood vessel.
  • the recess in the cannula housing can have various shapes so long as the valve body is of a corresponding cooperating shape to provide compression force in an appropriate direction tending to close the opening in the valve body. It is to be understood that only the preferred embodiments have been shown and described and that all changes and modifications that come within the spirit of the invention are desired to be protected.

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

L'invention concerne une canule hémostatique comprenant un boîtier (10) à travers lequel est formé un passage (11) aux dimensions conçues pour permettre le montage d'un cathéter et d'un corps de valve (1') à l'intérieur. Un orifice (3') pratiqué à travers ce corps de valve (1') forme un joint autour d'un cathéter intégré dans la canule. Un anneau bosselé (7') entoure l'orifice (3'). Lors du retrait du cathéter, le corps de valve (1') s'obture, bloquant ainsi la pénétration de l'air dans le vaisseau sanguin du patient, et empêchant également le sang de s'écouler du vaisseau sanguin du patient. Le boîtier de la canule (10) comporte également une entrée latérale (47) permettant l'introduction de fluides dans le vaisseau sanguin du patient.
PCT/US1995/001979 1994-02-15 1995-02-15 Canule hemostatique WO1995021642A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU19667/95A AU1966795A (en) 1994-02-15 1995-02-15 Hemostasis cannula

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19684694A 1994-02-15 1994-02-15
US08/196,846 1994-02-15

Publications (1)

Publication Number Publication Date
WO1995021642A1 true WO1995021642A1 (fr) 1995-08-17

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ID=22727012

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1995/001979 WO1995021642A1 (fr) 1994-02-15 1995-02-15 Canule hemostatique

Country Status (2)

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AU (1) AU1966795A (fr)
WO (1) WO1995021642A1 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0868203A1 (fr) * 1995-10-24 1998-10-07 Incorporated Cook Cannule d'hemostase
JP2000084091A (ja) * 1998-09-11 2000-03-28 Nippon Zeon Co Ltd 医療用弁体
US6663599B2 (en) * 1992-05-06 2003-12-16 Cook Incorporated Hemostasis cannula
CN103623500A (zh) * 2012-08-24 2014-03-12 株式会社戈德曼 医疗用阀装置
US8753317B2 (en) 1992-05-06 2014-06-17 Cook Medical Technologies Llc Hemostasis cannula

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3853127A (en) * 1973-04-03 1974-12-10 R Spademan Elastic sealing member
US4610665A (en) * 1983-01-18 1986-09-09 Terumo Kabushiki Kaisha Medical instrument
US4809679A (en) * 1986-11-19 1989-03-07 Olympus Optical Co., Ltd. Forceps plug for endoscopes
US5006133A (en) * 1989-04-05 1991-04-09 Sulzer Brothers Limited Method and apparatus for deoxidation of sea-water
US5114408A (en) * 1990-10-18 1992-05-19 Daig Corporation Universal hemostasis valve having improved sealing characteristics
US5167637A (en) * 1990-11-01 1992-12-01 Sherwood Medical Company Valve membrane for a catheter introducer hemostatic valve
US5211633A (en) * 1992-06-24 1993-05-18 Stouder Jr Albert E Selectable seal cannula

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3853127A (en) * 1973-04-03 1974-12-10 R Spademan Elastic sealing member
US4610665A (en) * 1983-01-18 1986-09-09 Terumo Kabushiki Kaisha Medical instrument
US4809679A (en) * 1986-11-19 1989-03-07 Olympus Optical Co., Ltd. Forceps plug for endoscopes
US5006133A (en) * 1989-04-05 1991-04-09 Sulzer Brothers Limited Method and apparatus for deoxidation of sea-water
US5114408A (en) * 1990-10-18 1992-05-19 Daig Corporation Universal hemostasis valve having improved sealing characteristics
US5167637A (en) * 1990-11-01 1992-12-01 Sherwood Medical Company Valve membrane for a catheter introducer hemostatic valve
US5211633A (en) * 1992-06-24 1993-05-18 Stouder Jr Albert E Selectable seal cannula

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6663599B2 (en) * 1992-05-06 2003-12-16 Cook Incorporated Hemostasis cannula
US7445611B2 (en) 1992-05-06 2008-11-04 Cook Incorporated Hemostasis cannula
US8753317B2 (en) 1992-05-06 2014-06-17 Cook Medical Technologies Llc Hemostasis cannula
EP0868203A1 (fr) * 1995-10-24 1998-10-07 Incorporated Cook Cannule d'hemostase
EP0868203A4 (fr) * 1995-10-24 1999-11-03 Cook Inc Cannule d'hemostase
JP2007190428A (ja) * 1995-10-24 2007-08-02 Cook Inc 止血カニューレ
JP2000084091A (ja) * 1998-09-11 2000-03-28 Nippon Zeon Co Ltd 医療用弁体
CN103623500A (zh) * 2012-08-24 2014-03-12 株式会社戈德曼 医疗用阀装置

Also Published As

Publication number Publication date
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