WO1995018604A1 - Traitement topique de la photophobie oculaire - Google Patents

Traitement topique de la photophobie oculaire Download PDF

Info

Publication number
WO1995018604A1
WO1995018604A1 PCT/IB1995/000003 IB9500003W WO9518604A1 WO 1995018604 A1 WO1995018604 A1 WO 1995018604A1 IB 9500003 W IB9500003 W IB 9500003W WO 9518604 A1 WO9518604 A1 WO 9518604A1
Authority
WO
WIPO (PCT)
Prior art keywords
ocular
photophobia
ophthalmically acceptable
surgery
group
Prior art date
Application number
PCT/IB1995/000003
Other languages
English (en)
Inventor
Troy Albert Reaves, Jr.
Original Assignee
Ciba-Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba-Geigy Ag filed Critical Ciba-Geigy Ag
Priority to AU12493/95A priority Critical patent/AU1249395A/en
Publication of WO1995018604A1 publication Critical patent/WO1995018604A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention se rapporte à l'utilisation d'un agent anti-inflammatoire non stéroïdien dans la préparation d'une composition pharmaceutique ophtalmique destinée à prévenir, traiter ou maîtriser la photophobie oculaire.
PCT/IB1995/000003 1994-01-11 1995-01-03 Traitement topique de la photophobie oculaire WO1995018604A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU12493/95A AU1249395A (en) 1994-01-11 1995-01-03 Topical treatment of ocular photophobia

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18017894A 1994-01-11 1994-01-11
US08/180,178 1994-01-11

Publications (1)

Publication Number Publication Date
WO1995018604A1 true WO1995018604A1 (fr) 1995-07-13

Family

ID=22659506

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB1995/000003 WO1995018604A1 (fr) 1994-01-11 1995-01-03 Traitement topique de la photophobie oculaire

Country Status (4)

Country Link
AU (1) AU1249395A (fr)
IL (1) IL112256A0 (fr)
WO (1) WO1995018604A1 (fr)
ZA (1) ZA95134B (fr)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999059634A1 (fr) * 1998-05-15 1999-11-25 Wakamoto Pharmaceutical Co., Ltd. Gouttes oculaires anti-inflammatoires
US8920820B2 (en) 2001-12-12 2014-12-30 Boehringer Ingelheim Vetmedica Gmbh Highly concentrated stable meloxicam solutions for needleless injection
US8992980B2 (en) 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
US9101529B2 (en) 2009-10-12 2015-08-11 Boehringer Ingelheim Vetmedica Gmbh Containers for compositions comprising meloxicam
US9149480B2 (en) 2010-03-03 2015-10-06 Boehringer Ingeleheim Vetmedica GmbH Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
US9993557B2 (en) 2000-06-20 2018-06-12 Boehringer Ingelheim Vetmedica Gmbh Highly concentrated stable meloxicam solutions
US10548901B2 (en) 2004-02-23 2020-02-04 Boehringer Ingelheim Vetmedica Gmbh Meloxicam for the treatment of respiratory diseases in pigs
US11643429B2 (en) * 2019-04-18 2023-05-09 Azura Ophthalmics Ltd. Compounds and methods for the treatment of ocular disorders

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
D.G.TINKELMAN: "Double-Masked, Paired-Comparison Clinical Study of Ketorolac Tromethamine 0.5% Ophthalmic Solution Compared with Placebo Eyedrops in the Treatment of Seasonal Allergic Conjunctivitis", SURV.OPHTHALMOL., vol. 38, no. SUPP, July 1993 (1993-07-01), pages 133 - 140 *
J.E.BLAYDES ET AL.: "Flurbiprofen 0.03% for the control of inflammation following cataract extraction by phacoemulsification", J. CATARACT REFRACT. SURG., vol. 19, no. 4, July 1993 (1993-07-01), pages 481 - 487 *
J.FRUCHT-PERY ET AL.: "The Effect of Topical Administration of Indomethacin on Symptoms in Corneal Scars and Edema", AM.J.OPHTHALMOL., vol. 112, no. 2, 15 August 1991 (1991-08-15) *
M.G.HECHANOVA, JR.: "A DOUBLE-BLIND STUDY COMPARING SODIUM CROMOGLYCATE EYE OINTMENT WITH PLACEBO IN THE TREATMENT OF CHRONIC ALLERGIC CONJUNCTIVITIS", CLIN. TRIALS J., vol. 21, no. 2, 1984, pages 59 - 66 *
M.L.RUGGIERI ET AL.: "Double-blind group comparative trial of sodium cromoglycate eye ointment and placebo in the treatment of allergic eye diseases", ANN. ALLERGY, vol. 58, no. 2, 1987, pages 109 - 112 *
N.A.SHER ET AL.: "Topical Diclofenac in the Treatment of Ocular Pain After Excimer Photorefractive Keratectomy", REFRACT.CORNEAL.SURG., vol. 9, no. 6, November 1993 (1993-11-01), pages 425 - 436 *
T.HIRAMITSU: "Topical aspirin solution relieved acute pain due to contact lens wear", JPN.J.OPHTHALMOL., vol. 42, no. 2, February 1988 (1988-02-01), pages 179 - 182 *
Z.BALLAS ET AL.: "Clinical Evaluation of Ketorolac Tromethamine 0.5% Ophthalmic Solution for the Treatment of Seasonal Allergic Conjunctivitis", SURV.OPHTHALMOL., vol. 38, no. SUPP, July 1993 (1993-07-01), pages 141 - 148 *

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999059634A1 (fr) * 1998-05-15 1999-11-25 Wakamoto Pharmaceutical Co., Ltd. Gouttes oculaires anti-inflammatoires
US9993557B2 (en) 2000-06-20 2018-06-12 Boehringer Ingelheim Vetmedica Gmbh Highly concentrated stable meloxicam solutions
US8920820B2 (en) 2001-12-12 2014-12-30 Boehringer Ingelheim Vetmedica Gmbh Highly concentrated stable meloxicam solutions for needleless injection
US10098891B2 (en) 2001-12-12 2018-10-16 Boehringer Ingelheim Vetmedica Gmbh Highly concentrated stable meloxicam solutions for needleless injection
US9066955B2 (en) 2002-10-25 2015-06-30 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
US8992980B2 (en) 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
US10548901B2 (en) 2004-02-23 2020-02-04 Boehringer Ingelheim Vetmedica Gmbh Meloxicam for the treatment of respiratory diseases in pigs
US9186296B2 (en) 2009-10-12 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh Containers for compositions comprising meloxicam
US9101529B2 (en) 2009-10-12 2015-08-11 Boehringer Ingelheim Vetmedica Gmbh Containers for compositions comprising meloxicam
US9149480B2 (en) 2010-03-03 2015-10-06 Boehringer Ingeleheim Vetmedica GmbH Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
US9943486B2 (en) 2010-05-05 2018-04-17 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
US11643429B2 (en) * 2019-04-18 2023-05-09 Azura Ophthalmics Ltd. Compounds and methods for the treatment of ocular disorders

Also Published As

Publication number Publication date
AU1249395A (en) 1995-08-01
ZA95134B (en) 1995-07-11
IL112256A0 (en) 1995-03-30

Similar Documents

Publication Publication Date Title
Colin The role of NSAIDs in the management of postoperative ophthalmic inflammation
US5811446A (en) Prophylactic and therapeutic methods for ocular degenerative diseases and inflammations and histidine compositions therefor
US5610184A (en) Method for sustained and extended corneal analgesia
KR100889170B1 (ko) 안구 건조의 치료에 있어서 리멕솔론의 용도
JP5583310B2 (ja) 眼球の症状の予防及び治療のための眼科用製剤
US4454151A (en) Use of pyrrolo pyrroles in treatment of ophthalmic diseases
Koay The emerging roles of topical non-steroidal anti-inflammatory agents in ophthalmology.
AU695888B2 (en) Use of non-steroidal cyclooxygenase inhibitors to treat elevated intraocular pressure
AU2011274245B2 (en) Composition for prevention and treatment of contact lens papillary conjunctivitis and allergic eye disease
Kenyon Decision-making in the therapy of external eye disease: noninfected corneal ulcers
Nichols et al. Topical nonsteroidal anti-inflammatory agents in ophthalmology
WO1995018604A1 (fr) Traitement topique de la photophobie oculaire
US6531120B2 (en) Ophthalmic histamine compositions and uses thereof
Gallenga et al. Efficacy of diclofenac eyedrops in preventing postoperative inflammation and long-term cystoid macular edema
MXPA06013170A (es) Metodo para tratar trastornos de queratoconjuntivitis seca y uveitis.
JPS58174310A (ja) 抗炎症点眼剤
Kymionis et al. Dry eye after photorefractive keratectomy with adjuvant mitomycin C
FRASER-SMITH et al. Effect of ketorolac on Pseudomonas aeruginosa ocular infection in rabbits
US6399107B1 (en) Use of inhibitors of gag synthesis for the treatment of corneal haze
KR20000048671A (ko) 각막 상피하 혼탁 억제제
WO2023098537A1 (fr) Nouvelle utilisation d'alanyl-glutamine et composition ophtalmique comprenant de l'alanyl-glutamine
Hashemian et al. The effect of topical diclofenac sodium 0.1% on the corneal epithelial healing after photorefractive keratectomy
CA2177578C (fr) Inhibiteurs non steroides pour le traitement de l'elevation de la pression intraoculaire
WO2020152527A1 (fr) Compositions pharmaceutiques ophtalmiques à base de vitamines, d'acides aminés et de minéraux pour le traitement de la cataracte immature

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AU CA FI JP MX NO NZ US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: CA