WO1995008328A1 - Composition de traitement et traitement cosmetique du cuir chevelu - Google Patents

Composition de traitement et traitement cosmetique du cuir chevelu Download PDF

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Publication number
WO1995008328A1
WO1995008328A1 PCT/US1994/010799 US9410799W WO9508328A1 WO 1995008328 A1 WO1995008328 A1 WO 1995008328A1 US 9410799 W US9410799 W US 9410799W WO 9508328 A1 WO9508328 A1 WO 9508328A1
Authority
WO
WIPO (PCT)
Prior art keywords
scalp
amount
hair
treatment composition
estrone
Prior art date
Application number
PCT/US1994/010799
Other languages
English (en)
Inventor
David Roberts
Original Assignee
David Roberts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by David Roberts filed Critical David Roberts
Publication of WO1995008328A1 publication Critical patent/WO1995008328A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth

Definitions

  • the present invention relates to a scalp treatment composition and a method of treating the scalp. More particularly, a composition based upon an estrogenic hormone, a keratolytic agent and an emollient is used to treat the scalp. BACKGROUND OF THE INVENTION
  • the hair covering of an animal specifically, the coating of hairs on a human scalp varies from individual to individual. Characteristics of hair can range from coarse thick hair to various degrees of fine, thin or limp hair. Alopecia or baldness is the loss of hair from areas where it is normally present. Various remedies for baldness have been proposed.
  • compositions for topical application to mammalian skin or hair for inducing, maintaining or increasing hair growth.
  • These compositions contain a chemical inhibitor chosen from proteoglycanase inhibitors, glycosaminoglycanase inhibitors, glycosaminoglycan chain cellular uptake inhibitors or mixtures thereof.
  • the hair treatment concentrate comprises (i) from about 0.08 to about 9 wt %, preferably about 5 to 6 wt %, of aged or unaged glyoxal; (ii) about 0.2 to about 9 wt %, preferably about 5 to 6 wt %, of urea or thiourea; and (iii) as an inert carrier, water, a lower alkanol or mixtures thereof.
  • use of the hair treatment concentrate can beautify thick, thin and damaged hair in an efficient manner.
  • use of the hair treatment concentrate in combination with a hair setting mousse beautifies hair, shortens the time required to achieve a desirable look and improves hold.
  • the inventor has found that use of a scalp treatment composition in combination with the hair treatment concentrate reported in U.S. Patent No. 5,181,529 to Roberts and U.S. Patent No. 3,650,280 to Roberts et al. is capable of resulting in one or more of the following: arresting abnormal hair loss; strengthening hair; and promoting hair growth.
  • one of the objects of the subject invention is to provide a scalp treatment composition for arresting abnormal hair loss.
  • nother object of the invention is to provide a scalp treatment process for arresting abnormal hair loss.
  • Another object of the invention is to provide a scalp treatment composition and process for containing or reducing male-patterned baldness.
  • An object of the invention is to provide a scalp treatment composition for strengthening the remaining hair in balding individuals. Another object is to provide a scalp treatment process for strengthening the remaining hair in balding individuals.
  • An object of the invention is to provide a scalp treatment for promoting hair growth. Another object is to provide a scalp treatment process for promoting hair growth.
  • the present invention provides a scalp treatment composition for topical application which is to be used with the hair treatment concentrate taught in U.S. Patent No. 5,181,529 to Roberts and U.S. Patent No. 3,650,280 to Roberts et al.
  • the present invention provides a scalp treatment composition for topical application comprised of an estrogenic hormone in an amount at least about 4.2X10 * % w/w, a keratolytic agent in an amount at least about 0.59 % w/w, and an emollient in an amount at least about 59.0 % w/w.
  • the scalp treatment composition may also be used in the two-step hair treatment regime as taught in U.S. Patent No. 5,181,529 to Roberts.
  • the scalp treatment composition is applied on top of the hair treatment concentrate or hair treatment concentrate and mousse.
  • the scalp treatment composition is left on the scalp for at least about six hours.
  • the hair treatment concentrate or the hair treatment concentrate and mousse according to the two-step hair treatment regime as taught in U.S. Patent No. 5,181,529 to Roberts, may be reapplied on top of the scalp treatment composition without shampooing. If additional body is required, a grooming composition may be applied as required.
  • DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS As used herein, the term “arresting" abnormal hair loss means preventing or inhibiting excess hair loss. "Strengthening" hair means changing the hair in such a way that the hair appears thicker, heavier and fuller.
  • “Promoting” hair growth means increasing new hair growth. "Lifting” the hair from the scalp makes hair look thicker. "Body” means the hair feels thicker. Hair can have body, i.e. feel thicker, but will not look thicker if the hair remains flat to the head and is not lifted off the scalp. "Setting” contemplates all the operations commonly employed to style hair and includes curling, waving, arranging and the like.
  • the invention comprises a scalp treatment composition for topical application for use with a hair treatment concentrate.
  • the scalp treatment composition comprises (i) an estrogenic hormone; (ii) a keratolytic agent; and (iii) an emollient.
  • the composition can also optionally comprise a substance that emits a pleasant odor such as a perfume in an amount sufficient to make the composition acceptable to the consumer and pleasant to use.
  • the scalp treatment composition comprises an estrogenic hormone in an amount at least about 4.2X10 "4 % w/w (4.2X10 "4 gm/100 gm) .
  • the scalp treatment composition comprises an estrogenic hormone in an amount not more than about 8.5xl0 "3 % w/w (8.5xl0 "3 gm/100 gm) .
  • the amount of estrone is equal to 10,000 units per fluid ounce plus 10 %.
  • the estrogenic hormone is estrone, preferably estrone USP.
  • USP United States Pharmacopeia
  • NF National Formulary
  • the scalp treatment composition comprises a keratolytic agent in an amount at least about 0.59 % w/w (0.59 gm/100 gm) . In one embodiment, the scalp treatment composition comprises a keratolytic agent in an amount not more than about 4.7 % w/w (4.7 gm/100 gm) .
  • the keratolytic agent may be resorcinol monoacetate, salicylic acid and the like. In a preferred embodiment, the keratolytic agent is resorcinol monoacetate, preferably resorcinol monoacetate NF.
  • the scalp treatment composition also comprises an emollient in an amount at least about 59.0 % w/w (59.0 gm/100 gm) .
  • the scalp treatment composition comprises an emollient in an amount not more than about 99.4 % w/w (99.4 gm/100 gm) .
  • the emollient may be isopropyl myristate, isopropyl palmitate, hexyl laurate and the like.
  • the emollient is isopropyl myristate, preferably isopropyl myristate cosmetic grade.
  • the scalp treatment composition may comprise a perfume in an amount at least about 0.59 % w/w (0.59 gm/100 gm) .
  • the scalp treatment composition comprises a perfume in an amount not more than about 2.9 % w/w (2.9 gm/100 gm) .
  • the estrone is dissolved in small increments of isopropyl myristate with the aid of heat. Those skilled in the art of formulating cosmetics will understand the preparation of this formulation.
  • the scalp treatment composition is applied sparingly to the scalp. A small amount, e.g., at least about 0.1 ml, of the scalp treatment composition is applied to the scalp by any method satisfactory to topically apply the composition to the scalp.
  • the composition may be dispensed onto the palm of one hand and the finger-tips of the other hand may be used as a means of applying the composition to the scalp.
  • the scalp treatment composition is left on the scalp for at least about six hours.
  • the scalp treatment composition is used in combination with the hair treatment concentrate as taught in U.S. Patent No. 5,181,529 to Roberts and U.S. Patent No. 3,650,280 to Roberts et al.
  • the scalp treatment composition of the present invention may also be used in combination with the two-step hair treatment regime as taught in U.S. Patent No. 5,181,529 to Roberts.
  • a hair treatment concentrate in an amount sufficient to provide lift and body to the hair is initially applied to hair that is to be treated, wherein the hair treatment concentrate comprises: about
  • a scalp treatment composition comprises: an estrogenic hormone; a keratolytic agent; and an emollient.
  • the scalp treatment composition is left on the scalp for at least about six hours.
  • a grooming composition may be applied as required. This process may be repeated until the next shampoo.
  • the hair treatment concentrate when used in combination with a scalp treatment composition comprising an estrogenic hormone and a keratolytic agent when present in a suitable amount is capable of resulting in one or more of the following: arresting abnormal hair loss; strengthening hair; and promoting hair growth.
  • an estrogenic hormone in an amount at least about 4.2X10" 4 % w/w
  • a keratolytic agent in an amount at least about 0.59 % w/w
  • an emollient in an amount at least about 59.0 % w/w
  • the scalp treatment composition contemplated by this invention includes those forms in which the compound is applied externally by direct contact with the skin surface to be treated such as emulsions, lotions and gels.
  • EXAMPLE 1 A scalp treatment composition having the following formulation, the total weight being equal to 100 g was prepared:
  • estrone USP 0.0039 % w/w (0.0039 g/100 g) resorcinol monoacetate 2.3500 % w/w (2.3500 g/100 g) NF isopropyl myristate, 96.4661 % w/w (96.4661 g/100 g) cosmetic grade perfume 1.1800 % w/w (1.1800 g/100 g)
  • estrone was dissolved in small increments of isopropyl myristate. Dissolution of the estrone was aided by means of heat.
  • a hair treatment concentrate and a hair setting mousse were applied to the hair according to U.S. Patent 5,181,529. This two-step hair treatment was followed by application to the scalp of the scalp treatment composition of Example 1.
  • the scalp treatment composition was applied sparingly to the scalp e.g., about 0.1 ml.
  • the scalp treatment composition was placed on the palm of one hand, spread onto the finger tips of the other hand and worked into the scalp.
  • the scalp treatment composition was left on the scalp overnight.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

L'invention concerne une composition de traitement du cuir chevelu destinée à être appliquée localement, ainsi qu'un procédé de traitement du cuir chevelu consistant à appliquer à ce dernier la composition de traitement comprenant une hormone ÷strogène, un agent keratolytique ainsi qu'un émollient.
PCT/US1994/010799 1993-09-24 1994-09-23 Composition de traitement et traitement cosmetique du cuir chevelu WO1995008328A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12699693A 1993-09-24 1993-09-24
US08/126,996 1993-09-24

Publications (1)

Publication Number Publication Date
WO1995008328A1 true WO1995008328A1 (fr) 1995-03-30

Family

ID=22427788

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1994/010799 WO1995008328A1 (fr) 1993-09-24 1994-09-23 Composition de traitement et traitement cosmetique du cuir chevelu

Country Status (2)

Country Link
IL (1) IL109504A0 (fr)
WO (1) WO1995008328A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017208463A1 (fr) * 2016-06-03 2017-12-07 花王株式会社 Produit cosmétique capillaire

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3650280A (en) * 1969-12-03 1972-03-21 David Roberts Cosmetic treatment of hair with thiourea or urea and glyoxal
US4508707A (en) * 1981-11-09 1985-04-02 Kakudai Shosan Kabushiki Kaisha Hair tonic composition
US5015470A (en) * 1986-12-23 1991-05-14 Gibson Walter T Cosmetic composition
US5181529A (en) * 1991-07-18 1993-01-26 David Roberts Kit and two-step cosmetic treatment for hair

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3650280A (en) * 1969-12-03 1972-03-21 David Roberts Cosmetic treatment of hair with thiourea or urea and glyoxal
US4508707A (en) * 1981-11-09 1985-04-02 Kakudai Shosan Kabushiki Kaisha Hair tonic composition
US5015470A (en) * 1986-12-23 1991-05-14 Gibson Walter T Cosmetic composition
US5181529A (en) * 1991-07-18 1993-01-26 David Roberts Kit and two-step cosmetic treatment for hair

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017208463A1 (fr) * 2016-06-03 2017-12-07 花王株式会社 Produit cosmétique capillaire

Also Published As

Publication number Publication date
IL109504A0 (en) 1994-08-26

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