WO1995000184B1 - Dried hydrogel from hydrophylic-hygroscopic polymer - Google Patents

Dried hydrogel from hydrophylic-hygroscopic polymer

Info

Publication number
WO1995000184B1
WO1995000184B1 PCT/US1994/007066 US9407066W WO9500184B1 WO 1995000184 B1 WO1995000184 B1 WO 1995000184B1 US 9407066 W US9407066 W US 9407066W WO 9500184 B1 WO9500184 B1 WO 9500184B1
Authority
WO
WIPO (PCT)
Prior art keywords
therapeutic device
therapeutic
hydrogel
wound
liquid medium
Prior art date
Application number
PCT/US1994/007066
Other languages
French (fr)
Other versions
WO1995000184A1 (en
Filing date
Publication date
Priority claimed from US08/082,028 external-priority patent/US5409703A/en
Application filed filed Critical
Priority to AU71153/94A priority Critical patent/AU7115394A/en
Priority to KR1019950705867A priority patent/KR100343293B1/en
Priority to AT94920306T priority patent/ATE218376T1/en
Priority to JP50307795A priority patent/JP2992835B2/en
Priority to EP94920306A priority patent/EP0705113B1/en
Priority to DE69430746T priority patent/DE69430746T2/en
Publication of WO1995000184A1 publication Critical patent/WO1995000184A1/en
Publication of WO1995000184B1 publication Critical patent/WO1995000184B1/en

Links

Abstract

A therapeutic medical device is described that is comprised of a dried hydrogel of a hydrophilic-hygroscopic polymer, such as an unmodified or modified polymeric carbohydrate, in the form of a solid foam. The dried hydrogel is prepared by preferably freeze-drying a hydrogel of this polymer in a liquid medium, such as water. The dried hydrogel can be sterilized by radiation or other means so that the sterilized product has a relatively indefinite shelf-life without refrigeration. The resultant dried hydrogel can be transformed into a hydrogel upon absorption of additional liquid medium. The described therapeutic device can serve as a dressing for a wound or lesion, drug delivery system, a hemostatic agent and a biologic response modifier. The described therapeutic device enhances the wound healing rate.

Claims

AMENDED CLAIMS[received by the International Bureau on 12 January 1995 (12.01.95); original claims 5, 6, 8, 32, 33, 40, 41, 43, 65, 66, 73, 74 and 76 cancelled; original claims 1, 4, 7, 10, 16, 35, 37, 42, 49, 69, 71, 75 and 77 amended; remaining claims unchanged (15 pages)]
1. A therapeutic device comprising a dried hydrogel in the form of a flexible solid foam that can be cut to the shape of a wound or lesion, said therapeutic device having gas bubbles dispersed throughout and being prepared by removing a liquid medium from a hydrogel, said hydrogel comprising particles of a hydrophilic-hygroscopic therapeutic polysaccharide dispersed in said liquid medium, wherein said therapeutic polysaccharide is obtained from aloe vera, said therapeutic device being capable of being transformed into said hydrogel upon absorption of additional liquid medium.
2. The therapeutic device as in claim 1, wherein said liquid medium comprises a polar solvent.
3. The therapeutic device as in claim 1, wherein said liquid medium comprises water.
6 5
4. The therapeutic device as in claim l, wherein said liquid medium is removed from said hydrogel by freeze drying.
5. Cancel.
6. Cancel.
7. The therapeutic device as in claim 1, wherein said hydrophilic-hygroscopic therapeutic polysaccharide obtained from aloe vera comprises acemannan.
8. Cancel.
9. The therapeutic device of claim 1, wherein said liquid medium comprises from about 5% to about 15% by weight of said therapeutic device.
10. The therapeutic device of claim l, wherein said hydrophilic-hygroscopic therapeutic polysaccharide comprises from about 85% to about 95% by weight of said therapeutic device.
6 6
11. The therapeutic device of claim 1, wherein said therapeutic device has a density of from about 0.002 g/cc to about 0.04 g/cc.
12. The therapeutic device of claim l, wherein said therapeutic device has a density of from about 0.02 g/cc to about 0.03 g/cc.
13. The therapeutic device as in claim 1, further comprising an antibiotic.
14. The therapeutic device as in claim 13, wherein said antibiotic is selected from the group consisting of tetracycline, oxytetracycline, and gentamycin.
15. The therapeutic device as in claim 1, further comprising a pharmaceutical agent.
16. The therapeutic device as in claim 15, wherein said pharmaceutical agent comprises an antihistamine.
6 7
17. The therapeutic device as in claim 15, wherein said pharmaceutical agent is selected from the group consisting of an anticancer agent, an antiviral agent, and an antifungal agent.
18. The therapeutic device as in claim 1, further comprising a biologic.
19. The therapeutic device as in claim 18, wherein said biologic is selected from the group consisting of a hormone and a growth factor.
20. The therapeutic device as in claim l, further comprising a hemostatic agent.
21. The therapeutic device as in claim 1, further comprising a microorganism.
22. The therapeutic device as in claim 21, wherein said microorganism comprises a vaccine.
23. The therapeutic device as in claim 22, wherein said vaccine comprises a modified live virus.
6 8 >
24. The therapeutic device as in claim 22, wherein said vaccine comprises a killed virus.
25. The therapeutic device as in claim 22, wherein said vaccine comprises viral components.
26. The therapeutic device as in claim 1, further comprising a preservative.
27. The therapeutic device as in claim 26, wherein said preservative is selected from the group consisting of methylparaben and benzethonium chloride.
28. The therapeutic device as in claim 1, further comprising a topical anesthetic.
29. The therapeutic device as in claim 1, further comprising a metal ion.
30. The therapeutic device as in claim 29, wherein said metal ion is selected from the group consisting of zinc, cobalt, iron, and manganese.
6 9
31. The therapeutic device as in claim 1, wherein said hydrogel comprises: about 99% by weight of water, and about 0.6% by weight of acemannan.
32. Cancel.
33. Cancel.
34. The therapeutic device as in claim 1, wherein said therapeutic device is sterilized by radiation.
35. A therapeutic device comprising a dried hydrogel in the form of a flexible solid foam that can be cut to the shape of a wound or lesion, said therapeutic device having gas bubbles dispersed throughout and being prepared by freeze-drying a hydrogel comprising: about 98.88% by weight of purified water, about 0.5% by weight of plasdone, about 0.002% by weight of benzethonium chloride, about 0.05% by weight of acemannan, and about 0.445% by weight of
7 0 hydroxyethylcellulose, said therapeutic device being capable of being transformed into said hydrogel upon absorption of additional water.
36. The therapeutic device as in claim 35, wherein said therapeutic device is sterilized by radiation.
37. A therapeutic device comprising from about 85% to about 95% by weight of a hydrophilic-hygroscopic therapeutic polysaccharide obtained from aloe vera dispersed in from about 5% to about 15% by weight of liquid medium, said therapeutic device being in the form of a flexible solid foam that can be cut to the shape of a wound or lesion, and said therapeutic device having gas bubbles dispersed throughout and being capable of being transformed into a hydrogel upon absorption of additional liquid medium.
38. The therapeutic device as in claim 37, wherein said liquid medium comprises from about 8% to about 12% by weight of said therapeutic device.
39. The therapeutic device as in claim 37, wherein said liquid medium comprises about 10% by weight of said therapeutic device.
40. Cancel.
41. Cancel.
42. The therapeutic device as in claim 37, wherein said hydrophilic-hygroscopic therapeutic polysaccharide obtained from aloe vera comprises acemannan.
43. Cancel.
44. The therapeutic device as in claim 37, wherein said therapeutic device comprises freeze-dried acemannan hydrogel.
45. The device as in claim 37, wherein said therapeutic device is adhered to an adhesive backing.
46. The therapeutic device as in claim 37, further comprising an antibiotic.
72
47. The therapeutic device as in claim 46, wherein said antibiotic is selected from the group consisting of tetracycline, oxytetracycline, and geπtamycin.
48. The therapeutic device as in claim 37, further c; -.prising a pharmaceutical agent.
49. The therapeutic device as in claim 48, wherein said pharmaceutical agent comprises an antihistamine.
50. The therapeutic device as in claim 48, wherein said pharmaceutical agent is selected from the group consisting of an anticancer agent, an antiviral agent, and an antifungal agent.
51. The therapeutic device as in claim 37, further comprising a biologic.
52. The therapeutic device as in claim 51, wherein said biologic is selected from the group consisting of a hormone and a growth factor.
7 3
53. The therapeutic device as in claim 37, further comprising a hemostatic agent.
54. The therapeutic device as in claim 37, further comprising a microorganism.
55. The therapeutic device as in claim 54, wherein said microorganism comprises a vaccine.
56. The therapeutic device as in claim 55, wherein said vaccine comprises a modified live virus.
57. The therapeutic device as in claim 55, wherein said vaccine comprises a killed virus.
58. The therapeutic device as in claim 55, wherein said vaccine comprises" viral components.
59. The therapeutic device as in claim 37, further comprising a preservative.
7 4
60. The therapeutic device as in claim 59, wherein said preservative is selected from the group consisting of methylparaben and benzethonium chloride.
61. The therapeutic device as in claim 37, further comprising a topical anesthetic.
62. The therapeutic device as in claim 37, further comprising a metal ion.
63. The therapeutic device as in claim 62, wherein said metal ion is selected from the group consisting of zinc, cobalt, iron, and manganese.
64. The therapeutic device as in claim 37, wherein said therapeutic device is sterilized by radiation.
65. Cancel.
66. Cancel.
75
67. A therapeutic device comprising from about 85% to about 95% by weight of acemannan dispersed in from about 5% to about 15% by weight of water, wherein said therapeutic device being in the form of a flexible solid foam that can be cut to the shape of a wound or lesion, said therapeutic device having gas bubbles dispersed throughout and being capable of being transformed into a hydrogel upon absorption of additional water.
68. The therapeutic device of claim 67, wherein said therapeutic device is sterilized by radiation.
69. A method of preparing a therapeutic device comprising: dispersing particles of a hydrophilic- hygroscopic therapeutic polysaccharide obtained from aloe vera in a liquid medium to give a hydrogel; and removing said liquid medium to give said therapeutic device in the form of a flexible solid foam that can be cut to the shape of a wound or lesion, said therapeutic device having gas bubbles dispersed throughout and being capable of being transformed into
7 6 said hydrogel upon absorption of additional liquid medium.
70. The method of claim 3, further comprising irradiating said therapeutic dev a.
71. A method of preparing a therapeutic device comprising: dispersing particles of a therapeutic polysaccharide obtained from aloe vera in water to give a hydrogel; and freeze-drying said hydrogel to give said therapeutic device in the form of a flexible solid foam that can be cut to the shape of a wound or lesion, said therapeutic device having gas bubbles dispersed throughout and being capable of being transformed into said hydrogel upon absorption of additional water.
72. The method of claim 71, further comprising irradiating said therapeutic device.
73. Cancel.
77
74. Cancel.
75. A method of treating a wound or lesion in an animal comprising: applying to said wound or lesion an effective amount of a therapeutic device comprising a dried hydrogel in the form of a flexible solid foam that can be cut to the shape of a wound or lesion, said therapeutic device having gas bubbles dispersed throughout, and being prepared by removing a liquid medium from a hydrogel, said hydrogel comprising particles of a hydrophilic- hygroscopic therapeutic polysaccharide dispersed in said liquid medium, wherein said therapeutic polysaccharide is obtained from aloe vera, said therapeutic device being capable of being transformed into said hydrogel upon absorption of additional liquid medium.
76. Cancel.
77. A method of treating a wound or lesion in an animal comprising: applying to said wound or lesion an effective amount of a therapeutic device comprising a freeze-dried
78 acemannan hydrogel in the form of a flexible solid foam that can be cut to the shape of a wound or lesion, sa' " therapeutic device having gas bubbles dispersed throughout and being capable of being transformed into a hydrogel upon absorption of additional water.
78. The method of claim 75, wherein said wound or lesion is in the oral cavity of said animal.
79. The method of claim 76, wherein said wound or lesion is in the oral cavity of said animal.
80. The method of claim 77, wherein said wound or lesion is in the oral cavity of said animal.
81. The method of claim 80, wherein said animal is a human and said wound or lesion is aphthous ulcers.
82. The method of claim 82, wherein said animal is a human and said wound or lesion is Herpes labialis.
7 9
STATEMENT UNDER ARTICLE 19
Applicants' invention pertains to a therapeutic device comprising a dried hydrogel in the form of a flexible solid foam that can be cut to the shape of a wound or lesion. The therapeutic device has gas bubbles dispersed throughout and is being prepared by removing a liquid medium from a hydrogel, which comprises particles of a hydrophilic-hygroscopic therapeutic polysaccharide dispersed in the liquid medium, wherein the therapeutic polysaccharide is obtained from aloe vera. The therapeutic device can be transformed into the hydrogel upon absorption of additional liquid medium.
It is respectfully submitted that Applicants' claims, as amended, are patentably distinct from the teaching of the cited references discussed below.
(1) GB,A, 2 067 214 teaches dried borax cross-linked cruar gum incorporated into the absorbents in diapers and such products. See, page 1, lines 110-128; and page 2, lines 3-14.
80 In contrast, Applicants' claims, as amended, are not directed to borax-cross-linked guar gum incorporated into the absorbents in a diaper. Rather, they are directed to therapeutic device containing therapeutic polysaccharide obtained from aloe vera.
(2) WO,A, 93 06802 A teaches a water-based natural or synthetic hydrocolloidal polymeric gel for dressing wounds. A gel-forming hydrocolloid polymer in dry particulate form, and a water source are required in the wound dressing. The liquid and dry solid components are initially separate but are mixed together within the package prior to use. See the abstract; and page 3, lines 12-24. The reference discloses the use of natural gum such as guar gum and locust bean gum as the hydrocolloid polymer. When guar gum is used, it is added with trace quantities of a cross-linker. See page 12, lines 20-28; and page 13, lines 15-27.
In contrast, Applicants' claims, as amended, are not directed to polymer in particulate form, and the device of the claims does not require premixing with water prior to use. Further, the claims are not directed to borax-cross-linked guar gum. Rather, they are directed to therapeutic device containing therapeutic polysaccharide obtained from aloe vera.
(3) WO,A, 90 01253 discloses that CARRISYN™ is the brand name given to the purified ethyl alcohol extract of the inner gel
81 of the leaves of Aloe barbadensis Miller. The CARRISYN™ extract is a fluffy white amorphous powder. See page 16, lines 11-35. In contrast, the claims, as amended, in the present application are directed to a therapeutic device comprising a dried hydrogel in the form of a flexible solid foam that can be cut to the shape of a wound or lesion.
(4) EP,A,0 568 368 teaches an absorbent, non-adherent, freeze-dried, fibre-free pad containing water-soluble biocompatible polymer and a liquid humectant in a certain ratio. The liquid humectants include glycerol. propylene glvcol. low molecular weight polyethylene glvcols. and mixture thereof. See Col. 2, lines 24-37.
In contrast, the claims, as amended, in the present application are directed to therapeutic devise containing therapeutic polysaccharide obtained from aloe vera. The devise is in the form of a flexible solid foam that can be cut to the shape of a wound or lesion. Further, the therapeutic device can be transformed into the hydrogel upon absorption of additional liquid medium.
Thus, the cited references, either singly or in combination, neither teach nor suggest Applicants' invention
82
PCT/US1994/007066 1993-06-24 1994-06-22 Dried hydrogel from hydrophylic-hygroscopic polymer WO1995000184A1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
AU71153/94A AU7115394A (en) 1993-06-24 1994-06-22 Dried hydrogel from hydrophylic-hygroscopic polymer
KR1019950705867A KR100343293B1 (en) 1993-06-24 1994-06-22 Dried hydrogel from hydrophylic-hygroscopic polymer
AT94920306T ATE218376T1 (en) 1993-06-24 1994-06-22 DRIED HYDROGELS FROM ACEMANNAN
JP50307795A JP2992835B2 (en) 1993-06-24 1994-06-22 Dried hydrogels from hydrophilic-hygroscopic polymers
EP94920306A EP0705113B1 (en) 1993-06-24 1994-06-22 Dried hydrogel from acemannan
DE69430746T DE69430746T2 (en) 1993-06-24 1994-06-22 DRIED HYDROGELS FROM ACEMANNAN

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/082,028 US5409703A (en) 1993-06-24 1993-06-24 Dried hydrogel from hydrophilic-hygroscopic polymer
US08/082,028 1993-06-24

Publications (2)

Publication Number Publication Date
WO1995000184A1 WO1995000184A1 (en) 1995-01-05
WO1995000184B1 true WO1995000184B1 (en) 1995-02-16

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1994/007066 WO1995000184A1 (en) 1993-06-24 1994-06-22 Dried hydrogel from hydrophylic-hygroscopic polymer

Country Status (10)

Country Link
US (1) US5409703A (en)
EP (1) EP0705113B1 (en)
JP (1) JP2992835B2 (en)
KR (1) KR100343293B1 (en)
CN (1) CN1127474A (en)
AT (1) ATE218376T1 (en)
AU (1) AU7115394A (en)
CA (1) CA2164624A1 (en)
DE (1) DE69430746T2 (en)
WO (1) WO1995000184A1 (en)

Families Citing this family (612)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5762620A (en) * 1992-04-02 1998-06-09 Ndm Acquisition Corp. Wound dressing containing a partially dehydrated hydrogel
US5423737A (en) * 1993-05-27 1995-06-13 New Dimensions In Medicine, Inc. Transparent hydrogel wound dressing with release tab
US5722942A (en) * 1994-02-18 1998-03-03 Kanebo, Ltd. Wound covering materials
US5503822A (en) * 1994-04-01 1996-04-02 Schulman; Jerome M. Medicated gel
GB2307687B (en) * 1994-09-29 1999-03-10 Innovative Tech Ltd Fibres
DE69533227T2 (en) * 1994-10-28 2005-07-07 Advanced Medical Solutions Ltd., Winsford REHYDRATED HYDROGEL
AU5638096A (en) * 1995-06-07 1996-12-30 Clarion Pharmaceuticals, Inc. Non-biological patch for hemostasis
JPH11507697A (en) * 1995-06-09 1999-07-06 エヌ． ドロハン，ウィリアム Chitin hydrogels, their preparation and use
US6258995B1 (en) * 1995-07-19 2001-07-10 Advanced Medical Solutions Limited Wound treatment composition
US5760102A (en) * 1996-02-20 1998-06-02 Carrington Laboratories, Inc. Uses of denture adhesive containing aloe extract
RS50101B (en) * 1996-02-24 2009-01-22 Boehringer Ingelheim International Gmbh., Pharmaceutical compositions for immunomodulation
GB9608222D0 (en) * 1996-04-20 1996-06-26 Innovative Tech Ltd Dehydrated hydrogels
GB9609474D0 (en) * 1996-05-08 1996-07-10 Innovative Tech Ltd Hydrogels
US5766520A (en) * 1996-07-15 1998-06-16 Universal Preservation Technologies, Inc. Preservation by foam formation
US6586763B2 (en) * 1996-06-25 2003-07-01 Northwestern University Organic light-emitting diodes and methods for assembly and emission control
US5834100A (en) * 1996-06-25 1998-11-10 Northwestern University Organic light-emitting dioddes and methods for assembly and emission control
US6399221B1 (en) 1996-06-25 2002-06-04 Northwestern University Organic light-emitting diodes and methods for assembly and emission control
US6939625B2 (en) * 1996-06-25 2005-09-06 Nôrthwestern University Organic light-emitting diodes and methods for assembly and enhanced charge injection
JP2000515401A (en) * 1996-07-10 2000-11-21 コロプラスト アクティーゼルスカブ Adhesives and the use of such adhesives
FR2750863B1 (en) * 1996-07-10 1998-09-25 Oreal USE OF A POLYHOLOSIDE IN A COMPOSITION FOR PROMOTING SKIN DEQUAMATION, AND COMPOSITION COMPRISING SAME
US6123662A (en) * 1998-07-13 2000-09-26 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
GB2318577B (en) * 1996-10-28 2000-02-02 Johnson & Johnson Medical Solvent dried polysaccharide sponges
US6303584B1 (en) 1996-11-20 2001-10-16 The University Of Montana Water soluble lipidated arabinogalactan
US5718916A (en) * 1997-02-03 1998-02-17 Scherr; George H. Alginate foam products
US6221997B1 (en) 1997-04-28 2001-04-24 Kimberly Ann Woodhouse Biodegradable polyurethanes
US20020018754A1 (en) * 1999-03-15 2002-02-14 Paul Albert Sagel Shapes for tooth whitening strips
US6355022B1 (en) 1998-05-01 2002-03-12 The Procter & Gamble Company Absorbent interlabial device with substance thereon for maintaining the device in position
WO1999004829A1 (en) * 1997-07-28 1999-02-04 Redmond Mary L Composition and process for the treatment of epidermal traumas such as decubitus ulcers
ZA987019B (en) * 1997-08-06 1999-06-04 Focal Inc Hemostatic tissue sealants
US6106849A (en) * 1998-01-21 2000-08-22 Dragoco Gerberding & Co. Ag Water soluble dry foam personal care product
DE19813663A1 (en) * 1998-03-27 1999-10-07 Beiersdorf Ag Wound dressings for removing disruptive factors from wound fluid
TWI243687B (en) 1998-04-21 2005-11-21 Teijin Ltd Pharmaceutical composition for application to mucosa
US7022683B1 (en) 1998-05-13 2006-04-04 Carrington Laboratories, Inc. Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation
US6313103B1 (en) * 1998-05-13 2001-11-06 Carrington Laboratories, Inc. Pectic substance as a growth factor stabilizer
US6591838B2 (en) 1998-07-06 2003-07-15 Scimed Life Systems, Inc. Implant system and method for bulking tissue
US6605294B2 (en) * 1998-08-14 2003-08-12 Incept Llc Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels
US6703047B2 (en) * 2001-02-02 2004-03-09 Incept Llc Dehydrated hydrogel precursor-based, tissue adherent compositions and methods of use
US7335220B2 (en) 2004-11-05 2008-02-26 Access Closure, Inc. Apparatus and methods for sealing a vascular puncture
IL127209A0 (en) * 1998-11-23 1999-09-22 Bio Silk Ltd Composition and method for treatment of hypertrophic skin accumulations and their prevention
US7129218B2 (en) * 1999-08-05 2006-10-31 Paradigm Biomedical, Inc. Use of rhamnolipids in wound healing, treatment and prevention of gum disease and periodontal regeneration
US6541678B2 (en) * 1999-09-27 2003-04-01 Brennen Medical, Inc. Immunostimulating coating for surgical devices
AR026073A1 (en) 1999-10-20 2002-12-26 Nycomed Gmbh PHARMACEUTICAL COMPOSITION AQUATIC CONTAINING CICLESONIDE
US6682721B2 (en) * 2000-03-17 2004-01-27 Lg Household & Healthcare Ltd. Patches for teeth whitening
US8652446B2 (en) * 2000-03-17 2014-02-18 Lg Household & Healthcare Ltd. Apparatus and method for whitening teeth
US6425856B1 (en) 2000-05-10 2002-07-30 Acorn Cardiovascular, Inc. Cardiac disease treatment and device
US7494669B2 (en) * 2001-02-28 2009-02-24 Carrington Laboratories, Inc. Delivery of physiological agents with in-situ gels comprising anionic polysaccharides
US6777000B2 (en) * 2001-02-28 2004-08-17 Carrington Laboratories, Inc. In-situ gel formation of pectin
EP1236466B1 (en) * 2001-02-28 2011-09-21 Axiomedic Ltd. Solid self-adhesive compositions for topical treatment of oral mucosal disorders
US8980334B2 (en) 2001-02-28 2015-03-17 Axiomedic Ltd. Double-layered absorbable solid compositions for the topical treatment of oral mucosal disorders
US20050191361A1 (en) * 2001-08-03 2005-09-01 Powederject Research Ltd. Hydrogel particle formation
DK1423066T3 (en) 2001-09-07 2008-11-17 Mardil Inc Method and apparatus for external cardiac stabilization
US7201930B2 (en) 2001-11-05 2007-04-10 Haley Jeffrey T Licorice root extract oral patch for treating canker sores
JP2005508980A (en) * 2001-11-05 2005-04-07 オラヘルス コーポレーション Stomatitis treatment with patches that promote healing and relieve pain
US20030124178A1 (en) * 2001-12-28 2003-07-03 Haley Jeffrey T. Soft, adherent, soluble oral patch
US20030155679A1 (en) * 2001-12-31 2003-08-21 Reeves William G. Method of making regenerated carbohydrate foam compositions
US20030175370A1 (en) * 2002-03-07 2003-09-18 Carrington Laboratories, Inc. Dispersed solid-containing complex carbohydrate
US6945448B2 (en) * 2002-06-18 2005-09-20 Zimmer Technology, Inc. Method for attaching a porous metal layer to a metal substrate
US7918382B2 (en) 2002-06-18 2011-04-05 Zimmer Technology, Inc. Method for attaching a porous metal layer to a metal substrate
US7252837B2 (en) * 2002-06-28 2007-08-07 Ethicon, Inc. Hemostatic wound dressing and method of making same
US20040101548A1 (en) * 2002-11-26 2004-05-27 Pendharkar Sanyog Manohar Hemostatic wound dressing containing aldehyde-modified polysaccharide
US20040106344A1 (en) * 2002-06-28 2004-06-03 Looney Dwayne Lee Hemostatic wound dressings containing proteinaceous polymers
US20040101546A1 (en) * 2002-11-26 2004-05-27 Gorman Anne Jessica Hemostatic wound dressing containing aldehyde-modified polysaccharide and hemostatic agents
US7279177B2 (en) * 2002-06-28 2007-10-09 Ethicon, Inc. Hemostatic wound dressings and methods of making same
US20040019360A1 (en) * 2002-07-25 2004-01-29 Farnsworth Ted R. Tissue repair device with a removable support member
US8524200B2 (en) 2002-09-11 2013-09-03 The Procter & Gamble Company Tooth whitening products
US6863924B2 (en) * 2002-12-23 2005-03-08 Kimberly-Clark Worldwide, Inc. Method of making an absorbent composite
US20040156904A1 (en) * 2003-02-12 2004-08-12 The Research Foundation Of State University Of New York Biodegradable polymer device
US7019191B2 (en) 2003-03-25 2006-03-28 Ethicon, Inc. Hemostatic wound dressings and methods of making same
WO2004096127A2 (en) * 2003-04-25 2004-11-11 Kos Life Sciences, Inc. Formation of strong superporous hydrogels
US9060770B2 (en) 2003-05-20 2015-06-23 Ethicon Endo-Surgery, Inc. Robotically-driven surgical instrument with E-beam driver
US20070084897A1 (en) 2003-05-20 2007-04-19 Shelton Frederick E Iv Articulating surgical stapling instrument incorporating a two-piece e-beam firing mechanism
US20040241212A1 (en) * 2003-05-30 2004-12-02 Pendharkar Sanyog Manohar Biodegradable hemostatic wound dressings
US7331979B2 (en) * 2003-06-04 2008-02-19 Access Closure, Inc. Apparatus and methods for sealing a vascular puncture
US9289195B2 (en) 2003-06-04 2016-03-22 Access Closure, Inc. Auto-retraction apparatus and methods for sealing a vascular puncture
US20040265371A1 (en) * 2003-06-25 2004-12-30 Looney Dwayne Lee Hemostatic devices and methods of making same
US20060199762A1 (en) * 2003-09-03 2006-09-07 Toshikazu Nakamura Skin ulcer preventive curative agent containing human recombinant hgf
US20050090905A1 (en) * 2003-10-23 2005-04-28 Hawkins Michael E. Porous implant with a dried, lubricious when wet, in vivo absorbable coating
US20050272153A1 (en) 2004-01-27 2005-12-08 Zou Xuenong Bone tissue engineering by ex vivo stem cells ongrowth into three-dimensional trabecular metal
US20050186240A1 (en) * 2004-02-23 2005-08-25 Ringeisen Timothy A. Gel suitable for implantation and delivery system
US20050255054A1 (en) * 2004-04-30 2005-11-17 Philp Graham K Jr Method for tooth whitening, in particular a system for tooth whitening using a dissolvable tray or strip
US8215531B2 (en) 2004-07-28 2012-07-10 Ethicon Endo-Surgery, Inc. Surgical stapling instrument having a medical substance dispenser
US11896225B2 (en) 2004-07-28 2024-02-13 Cilag Gmbh International Staple cartridge comprising a pan
AU2005266812B2 (en) * 2004-07-30 2010-07-29 Enwave Corporation Method for producing hydrocolloid foams
US8348971B2 (en) 2004-08-27 2013-01-08 Accessclosure, Inc. Apparatus and methods for facilitating hemostasis within a vascular puncture
EP1809342B1 (en) * 2004-10-20 2015-08-05 Ethicon, Inc. Absorbable hemostat
US20060258995A1 (en) * 2004-10-20 2006-11-16 Pendharkar Sanyog M Method for making a reinforced absorbable multilayered fabric for use in medical devices
US20060257457A1 (en) * 2004-10-20 2006-11-16 Gorman Anne J Method for making a reinforced absorbable multilayered hemostatic wound dressing
US7666803B2 (en) * 2004-10-20 2010-02-23 Ethicon, Inc. Reinforced absorbable multilayered fabric for use in medical devices
US9358318B2 (en) * 2004-10-20 2016-06-07 Ethicon, Inc. Method of making a reinforced absorbable multilayered hemostatic wound dressing
US8262693B2 (en) * 2004-11-05 2012-09-11 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
US20060134201A1 (en) * 2004-12-16 2006-06-22 Haley Jeffrey T Collagen troches for treating mouth lesions
US20060165611A1 (en) * 2005-01-26 2006-07-27 National Research Laboratories, Ltd. Composition for Treating and Preventing Periodontal Disease and Method of Use
US20060210515A1 (en) * 2005-03-18 2006-09-21 Mower Thomas E Hair growth formula
US20060210692A1 (en) * 2005-03-18 2006-09-21 Mower Thomas E Baby food composition
US7776365B2 (en) * 2005-03-18 2010-08-17 Sakura Properties, Llc Article with skin protecting and moisturizing compound
US20060210496A1 (en) * 2005-03-18 2006-09-21 Mower Thomas E Compositions for skin protection from ultraviolet damage
US7749545B2 (en) * 2005-03-18 2010-07-06 Sakura Properties, Llc Fucoidan compositions and methods for dietary and nutritional supplements
US20060210688A1 (en) * 2005-03-18 2006-09-21 Mower Thomas E Dehydrated sports drink powder
US20060210514A1 (en) * 2005-03-18 2006-09-21 Mower Thomas E Skin protection and moisturizing compositions and method of making the same
US7666448B2 (en) * 2005-03-18 2010-02-23 Sakura Properties, Llc Skin cleansing article
US20070020358A1 (en) * 2005-03-18 2007-01-25 Mower Thomas E Sports drink concentrate
US20060210697A1 (en) * 2005-03-18 2006-09-21 Mower Thomas E Infant formula composition
US7790216B2 (en) * 2005-04-19 2010-09-07 Zimmer Technology, Inc. Method for producing a zirconia-layered orthopedic implant component
US7806856B2 (en) * 2005-04-22 2010-10-05 Accessclosure, Inc. Apparatus and method for temporary hemostasis
US10159482B2 (en) 2005-08-31 2018-12-25 Ethicon Llc Fastener cartridge assembly comprising a fixed anvil and different staple heights
US11484312B2 (en) 2005-08-31 2022-11-01 Cilag Gmbh International Staple cartridge comprising a staple driver arrangement
US11246590B2 (en) 2005-08-31 2022-02-15 Cilag Gmbh International Staple cartridge including staple drivers having different unfired heights
US9237891B2 (en) 2005-08-31 2016-01-19 Ethicon Endo-Surgery, Inc. Robotically-controlled surgical stapling devices that produce formed staples having different lengths
US7934630B2 (en) 2005-08-31 2011-05-03 Ethicon Endo-Surgery, Inc. Staple cartridges for forming staples having differing formed staple heights
US7669746B2 (en) 2005-08-31 2010-03-02 Ethicon Endo-Surgery, Inc. Staple cartridges for forming staples having differing formed staple heights
DE102005050654A1 (en) * 2005-10-20 2007-04-26 LABTEC Gesellschaft für technologische Forschung und Entwicklung mbH lip paving
KR101363881B1 (en) * 2005-10-21 2014-02-17 에이다 파운데이션 Dental and endodontic filling materials and methods
US9259439B2 (en) 2005-10-21 2016-02-16 Ada Foundation Dual-phase cement precursor systems for bone repair
US9101436B2 (en) 2005-10-21 2015-08-11 Ada Foundation Dental and endodontic filling materials and methods
US20070106317A1 (en) 2005-11-09 2007-05-10 Shelton Frederick E Iv Hydraulically and electrically actuated articulation joints for surgical instruments
US20120292367A1 (en) 2006-01-31 2012-11-22 Ethicon Endo-Surgery, Inc. Robotically-controlled end effector
US11278279B2 (en) 2006-01-31 2022-03-22 Cilag Gmbh International Surgical instrument assembly
US8708213B2 (en) 2006-01-31 2014-04-29 Ethicon Endo-Surgery, Inc. Surgical instrument having a feedback system
US11224427B2 (en) 2006-01-31 2022-01-18 Cilag Gmbh International Surgical stapling system including a console and retraction assembly
US8820603B2 (en) 2006-01-31 2014-09-02 Ethicon Endo-Surgery, Inc. Accessing data stored in a memory of a surgical instrument
US7845537B2 (en) 2006-01-31 2010-12-07 Ethicon Endo-Surgery, Inc. Surgical instrument having recording capabilities
US11793518B2 (en) 2006-01-31 2023-10-24 Cilag Gmbh International Powered surgical instruments with firing system lockout arrangements
US8186555B2 (en) 2006-01-31 2012-05-29 Ethicon Endo-Surgery, Inc. Motor-driven surgical cutting and fastening instrument with mechanical closure system
US7753904B2 (en) 2006-01-31 2010-07-13 Ethicon Endo-Surgery, Inc. Endoscopic surgical instrument with a handle that can articulate with respect to the shaft
US20110290856A1 (en) 2006-01-31 2011-12-01 Ethicon Endo-Surgery, Inc. Robotically-controlled surgical instrument with force-feedback capabilities
US20110024477A1 (en) 2009-02-06 2011-02-03 Hall Steven G Driven Surgical Stapler Improvements
JP5010834B2 (en) * 2006-02-20 2012-08-29 帝國製薬株式会社 Patch
US20070208217A1 (en) 2006-03-03 2007-09-06 Acorn Cardiovascular, Inc. Self-adjusting attachment structure for a cardiac support device
US8349120B2 (en) * 2006-03-07 2013-01-08 Ora Health Corporation Multi-layer patch made on a sheet and enclosed in a blister
JP2009529589A (en) * 2006-03-15 2009-08-20 ザ・ユニバーシティ・オブ・シドニー Activated polymers that bind to biomolecules
US8992422B2 (en) 2006-03-23 2015-03-31 Ethicon Endo-Surgery, Inc. Robotically-controlled endoscopic accessory channel
US8795709B2 (en) * 2006-03-29 2014-08-05 Incept Llc Superabsorbent, freeze dried hydrogels for medical applications
US20070248655A1 (en) * 2006-04-21 2007-10-25 Haley Jeffrey T Lenticular shaped protective mouth sore discs
US20070248654A1 (en) * 2006-04-21 2007-10-25 Haley Jeffrey T Protective mouth sore discs made with corn starch
WO2007130748A1 (en) * 2006-05-03 2007-11-15 Discus Dental Impressions, Inc. Dental instruments having anti-microbial coating
US20070270882A1 (en) * 2006-05-19 2007-11-22 Acorn Cardiovascular, Inc. Pericardium management method for intra-pericardial surgical procedures
US8322455B2 (en) 2006-06-27 2012-12-04 Ethicon Endo-Surgery, Inc. Manually driven surgical cutting and fastening instrument
US20080097146A1 (en) * 2006-06-29 2008-04-24 Acorn Cardiovascular, Inc. Cardiac support device with low friction delivery structures
US7651462B2 (en) 2006-07-17 2010-01-26 Acorn Cardiovascular, Inc. Cardiac support device delivery tool with release mechanism
EP2077765A2 (en) 2006-09-13 2009-07-15 Accessclosure, Inc. Apparatus for sealing a vascular puncture
US7641608B1 (en) 2006-09-26 2010-01-05 Acorn Cardiovascular, Inc. Sectional cardiac support device and method of delivery
US8623842B2 (en) * 2006-09-27 2014-01-07 Hemostasis, Llc Hemostatic agent and method
US20080078802A1 (en) 2006-09-29 2008-04-03 Hess Christopher J Surgical staples and stapling instruments
US8414550B2 (en) * 2006-09-29 2013-04-09 Lexion Medical, Llc System and method to vent gas from a body cavity
US10568652B2 (en) 2006-09-29 2020-02-25 Ethicon Llc Surgical staples having attached drivers of different heights and stapling instruments for deploying the same
US11980366B2 (en) 2006-10-03 2024-05-14 Cilag Gmbh International Surgical instrument
WO2008080146A1 (en) * 2006-12-26 2008-07-03 Discus Dental, Llc Disposable tongue scraper
US11291441B2 (en) 2007-01-10 2022-04-05 Cilag Gmbh International Surgical instrument with wireless communication between control unit and remote sensor
US8652120B2 (en) 2007-01-10 2014-02-18 Ethicon Endo-Surgery, Inc. Surgical instrument with wireless communication between control unit and sensor transponders
US8684253B2 (en) 2007-01-10 2014-04-01 Ethicon Endo-Surgery, Inc. Surgical instrument with wireless communication between a control unit of a robotic system and remote sensor
US8701958B2 (en) 2007-01-11 2014-04-22 Ethicon Endo-Surgery, Inc. Curved end effector for a surgical stapling device
US11039836B2 (en) 2007-01-11 2021-06-22 Cilag Gmbh International Staple cartridge for use with a surgical stapling instrument
WO2008092228A1 (en) * 2007-02-01 2008-08-07 The University Of British Columbia Method of drying biological material
JP2010519183A (en) * 2007-02-06 2010-06-03 インセプト エルエルシー Polymerization using protein precipitation for elution of physiological solutions
US7604151B2 (en) 2007-03-15 2009-10-20 Ethicon Endo-Surgery, Inc. Surgical stapling systems and staple cartridges for deploying surgical staples with tissue compression features
US8893946B2 (en) 2007-03-28 2014-11-25 Ethicon Endo-Surgery, Inc. Laparoscopic tissue thickness and clamp load measuring devices
TW200904340A (en) 2007-05-11 2009-02-01 Mannatech Inc Processing of natural polysaccharides by selected non-pathogenic microorganisms and methods of making and using the same
WO2008140820A2 (en) * 2007-05-11 2008-11-20 Aloebiotics Research Labs, Inc. Aloe preparation for skin enhancement
US8931682B2 (en) 2007-06-04 2015-01-13 Ethicon Endo-Surgery, Inc. Robotically-controlled shaft based rotary drive systems for surgical instruments
US11564682B2 (en) 2007-06-04 2023-01-31 Cilag Gmbh International Surgical stapler device
US8133553B2 (en) 2007-06-18 2012-03-13 Zimmer, Inc. Process for forming a ceramic layer
US7753245B2 (en) 2007-06-22 2010-07-13 Ethicon Endo-Surgery, Inc. Surgical stapling instruments
US11849941B2 (en) 2007-06-29 2023-12-26 Cilag Gmbh International Staple cartridge having staple cavities extending at a transverse angle relative to a longitudinal cartridge axis
US8790345B2 (en) * 2007-08-21 2014-07-29 Zimmer, Inc. Titanium alloy with oxidized zirconium for a prosthetic implant
US20110129514A1 (en) * 2007-09-06 2011-06-02 Hossainy Syed F A Hygroscopic coating on a balloon device
US20110137243A1 (en) * 2007-09-06 2011-06-09 Abbott Cardiovascular Systems Inc. Coating On A Balloon Device
US20090074679A1 (en) * 2007-09-13 2009-03-19 Silverman Harvey N Tooth whitening methods and apparatuses
US20090088723A1 (en) * 2007-09-28 2009-04-02 Accessclosure, Inc. Apparatus and methods for treating pseudoaneurysms
US7993367B2 (en) * 2007-09-28 2011-08-09 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
US20110028709A1 (en) * 2007-10-31 2011-02-03 Mark Gerald Deacon-Shaw Methods for sterilizing glucans
EP2209426A4 (en) * 2007-11-02 2015-04-22 Incept Llc Apparatus and methods for sealing a vascular puncture
DE102007056465B4 (en) * 2007-11-22 2010-06-02 I.G. Bauerhin Gmbh Motor vehicle seat with seat heating
US8765170B2 (en) * 2008-01-30 2014-07-01 The Procter & Gamble Company Personal care composition in the form of an article
US7866527B2 (en) 2008-02-14 2011-01-11 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus with interlockable firing system
US8573465B2 (en) 2008-02-14 2013-11-05 Ethicon Endo-Surgery, Inc. Robotically-controlled surgical end effector system with rotary actuated closure systems
US11986183B2 (en) 2008-02-14 2024-05-21 Cilag Gmbh International Surgical cutting and fastening instrument comprising a plurality of sensors to measure an electrical parameter
RU2493788C2 (en) 2008-02-14 2013-09-27 Этикон Эндо-Серджери, Инк. Surgical cutting and fixing instrument, which has radio-frequency electrodes
US8758391B2 (en) 2008-02-14 2014-06-24 Ethicon Endo-Surgery, Inc. Interchangeable tools for surgical instruments
US7819298B2 (en) 2008-02-14 2010-10-26 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus with control features operable with one hand
US9179912B2 (en) 2008-02-14 2015-11-10 Ethicon Endo-Surgery, Inc. Robotically-controlled motorized surgical cutting and fastening instrument
US8636736B2 (en) 2008-02-14 2014-01-28 Ethicon Endo-Surgery, Inc. Motorized surgical cutting and fastening instrument
US11272927B2 (en) 2008-02-15 2022-03-15 Cilag Gmbh International Layer arrangements for surgical staple cartridges
US9770245B2 (en) 2008-02-15 2017-09-26 Ethicon Llc Layer arrangements for surgical staple cartridges
US8585646B2 (en) 2008-03-03 2013-11-19 Lexion Medical, Llc System and method to vent gas from a body cavity
US9061087B2 (en) * 2008-03-04 2015-06-23 Hemostasis, Llc Method of making a hemostatic sponge wound dressing comprising subjecting the sponge to water vapor
US9364206B2 (en) 2008-04-04 2016-06-14 Access Closure, Inc. Apparatus and methods for sealing a vascular puncture
US8029533B2 (en) 2008-04-04 2011-10-04 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
EP2666457B1 (en) * 2008-04-16 2020-06-17 The Procter & Gamble Company Process for forming a non-lathering personal care article in the form of a dissolvable solid foam
US9005230B2 (en) 2008-09-23 2015-04-14 Ethicon Endo-Surgery, Inc. Motorized surgical instrument
US8210411B2 (en) 2008-09-23 2012-07-03 Ethicon Endo-Surgery, Inc. Motor-driven surgical cutting instrument
US9386983B2 (en) 2008-09-23 2016-07-12 Ethicon Endo-Surgery, Llc Robotically-controlled motorized surgical instrument
US11648005B2 (en) 2008-09-23 2023-05-16 Cilag Gmbh International Robotically-controlled motorized surgical instrument with an end effector
US8608045B2 (en) 2008-10-10 2013-12-17 Ethicon Endo-Sugery, Inc. Powered surgical cutting and stapling apparatus with manually retractable firing system
US7833829B2 (en) * 2008-10-28 2010-11-16 Honeywell International Inc. MEMS devices and methods of assembling micro electromechanical systems (MEMS)
US8905760B2 (en) * 2008-11-04 2014-12-09 Duane C. Keller Methods and systems for progressively treating and controlling oral periopathogens causing systemic inflammations
US8956161B2 (en) 2008-11-04 2015-02-17 Duane C Keller Article and method for controlling oral-originated systemic disease
WO2010056915A1 (en) 2008-11-12 2010-05-20 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
JP5718245B2 (en) 2008-12-08 2015-05-13 ザ プロクター アンド ギャンブルカンパニー Personal care composition in the form of an article having a porous soluble solid structure
US8461090B2 (en) * 2008-12-08 2013-06-11 The Procter & Gamble Company Personal care composition in the form of an article having a porous, dissolvable solid structure
BRPI0922560A2 (en) * 2008-12-08 2019-09-24 Procter & Gamble surface resident cyclodextrin dissolvable porous solid substrates and perfume complexes
WO2010077627A2 (en) * 2008-12-08 2010-07-08 The Procter & Gamble Company Process of making an article for dissolution upon use to deliver surfactants
US20100291165A1 (en) * 2008-12-08 2010-11-18 Glenn Jr Robert Wayne Personal care composition in the form of an article having a hydrophobic surface-resident coating
US8517239B2 (en) 2009-02-05 2013-08-27 Ethicon Endo-Surgery, Inc. Surgical stapling instrument comprising a magnetic element driver
CA2751664A1 (en) 2009-02-06 2010-08-12 Ethicon Endo-Surgery, Inc. Driven surgical stapler improvements
US8444036B2 (en) 2009-02-06 2013-05-21 Ethicon Endo-Surgery, Inc. Motor driven surgical fastener device with mechanisms for adjusting a tissue gap within the end effector
US8409606B2 (en) 2009-02-12 2013-04-02 Incept, Llc Drug delivery through hydrogel plugs
EP2427233B1 (en) * 2009-05-04 2016-12-21 Incept Llc Biomaterials for track and puncture closure
US20110052663A1 (en) * 2009-09-01 2011-03-03 Hemostasis, Llc Hemostatic Sponge with Enzyme and Method of Manufacture
CA2780294C (en) 2009-11-09 2018-01-16 Spotlight Technology Partners Llc Polysaccharide based hydrogels
WO2011057133A1 (en) 2009-11-09 2011-05-12 Spotlight Technology Partners Llc Fragmented hydrogels
US8349787B2 (en) * 2009-12-08 2013-01-08 The Procter & Gamble Company Porous, dissolvable solid substrate and a cationic surfactant conditioner material
WO2011071964A1 (en) 2009-12-08 2011-06-16 The Procter & Gamble Company A porous, dissolvable solid substrate and a surface resident coating of cationic surfactant conditioner
JP5639659B2 (en) * 2009-12-08 2014-12-10 ザ プロクター アンド ギャンブルカンパニー Porous dissolvable solid substrate and surface residual coating containing matrix microspheres
WO2011079260A2 (en) * 2009-12-23 2011-06-30 Arizona Board Of Regents Acting For And On Behalf Of Arizona State University Stabilized virus like particles having enhanced mucosal immunogenicity
US8220688B2 (en) 2009-12-24 2012-07-17 Ethicon Endo-Surgery, Inc. Motor-driven surgical cutting instrument with electric actuator directional control assembly
US8851354B2 (en) 2009-12-24 2014-10-07 Ethicon Endo-Surgery, Inc. Surgical cutting instrument that analyzes tissue thickness
EP2536386A1 (en) 2010-02-16 2012-12-26 The Procter & Gamble Company A porous, dissolvable solid substrate and surface resident coating comprising a zync pyrithione
CN101890185B (en) * 2010-05-21 2012-12-12 天津大学 ZnO quantum dot vector/DNA composite-containing collagen-based composite cornea substitute, and preparation method and application thereof
US20180163325A1 (en) 2016-12-09 2018-06-14 Robert Wayne Glenn, Jr. Dissolvable fibrous web structure article comprising active agents
ES2792823T3 (en) 2010-07-02 2020-11-12 Procter & Gamble Soluble fibrous web structure article comprising active ingredients
CN102971408B (en) 2010-07-02 2016-03-02 宝洁公司 Betengent product
CN103025930B (en) 2010-07-02 2014-11-12 宝洁公司 Method for delivering an active agent
RU2541949C2 (en) 2010-07-02 2015-02-20 Дзе Проктер Энд Гэмбл Компани Filaments, containing active agent, non-woven cloths and methods of obtaining them
US9295663B2 (en) 2010-07-14 2016-03-29 Abbott Cardiovascular Systems Inc. Drug coated balloon with in-situ formed drug containing microspheres
US8783543B2 (en) 2010-07-30 2014-07-22 Ethicon Endo-Surgery, Inc. Tissue acquisition arrangements and methods for surgical stapling devices
US20120029405A1 (en) * 2010-07-31 2012-02-02 Anthony Cataldi Scented And Antiseptic Adhesive Bandage
US9364233B2 (en) 2010-09-30 2016-06-14 Ethicon Endo-Surgery, Llc Tissue thickness compensators for circular surgical staplers
US8857694B2 (en) 2010-09-30 2014-10-14 Ethicon Endo-Surgery, Inc. Staple cartridge loading assembly
US9629814B2 (en) 2010-09-30 2017-04-25 Ethicon Endo-Surgery, Llc Tissue thickness compensator configured to redistribute compressive forces
US9272406B2 (en) 2010-09-30 2016-03-01 Ethicon Endo-Surgery, Llc Fastener cartridge comprising a cutting member for releasing a tissue thickness compensator
US10945731B2 (en) 2010-09-30 2021-03-16 Ethicon Llc Tissue thickness compensator comprising controlled release and expansion
US9232941B2 (en) 2010-09-30 2016-01-12 Ethicon Endo-Surgery, Inc. Tissue thickness compensator comprising a reservoir
US11812965B2 (en) 2010-09-30 2023-11-14 Cilag Gmbh International Layer of material for a surgical end effector
US9241714B2 (en) 2011-04-29 2016-01-26 Ethicon Endo-Surgery, Inc. Tissue thickness compensator and method for making the same
US11849952B2 (en) 2010-09-30 2023-12-26 Cilag Gmbh International Staple cartridge comprising staples positioned within a compressible portion thereof
US11298125B2 (en) 2010-09-30 2022-04-12 Cilag Gmbh International Tissue stapler having a thickness compensator
US9386988B2 (en) 2010-09-30 2016-07-12 Ethicon End-Surgery, LLC Retainer assembly including a tissue thickness compensator
US8695866B2 (en) 2010-10-01 2014-04-15 Ethicon Endo-Surgery, Inc. Surgical instrument having a power control circuit
US8591229B2 (en) 2010-12-16 2013-11-26 Duane C. Keller Devices and methods for creating a positive pressure environment for treatment of oral biofilms associated with periodontal disease
US9820728B2 (en) 2011-01-19 2017-11-21 Access Closure, Inc. Apparatus and methods for sealing a vascular puncture
EP3461422B1 (en) 2011-01-19 2020-12-30 Access Closure, Inc. Methods for sealing a vascular puncture
US20120220973A1 (en) * 2011-02-28 2012-08-30 Jennifer Wing-Yee Chan Adhesive bandage
BR112013027794B1 (en) 2011-04-29 2020-12-15 Ethicon Endo-Surgery, Inc CLAMP CARTRIDGE SET
US9386968B2 (en) 2011-05-11 2016-07-12 Access Closure, Inc. Apparatus and methods for sealing a vascular puncture
US9072535B2 (en) 2011-05-27 2015-07-07 Ethicon Endo-Surgery, Inc. Surgical stapling instruments with rotatable staple deployment arrangements
US8425622B2 (en) 2011-05-27 2013-04-23 The Procter & Gamble Company Soluble solid hair coloring article
MX336048B (en) 2011-05-27 2016-01-07 Procter & Gamble Soluble solid hair coloring article.
US11207064B2 (en) 2011-05-27 2021-12-28 Cilag Gmbh International Automated end effector component reloading system for use with a robotic system
US20120330352A1 (en) * 2011-06-24 2012-12-27 Accessclosure, Inc. Transapical closure devices and methods for use
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
CN109200013A (en) 2011-12-05 2019-01-15 因赛普特有限责任公司 Medical organogel method and composition
DE202011052225U1 (en) * 2011-12-07 2013-03-11 Mcairlaid's Vliesstoffe Gmbh & Co. Kg Spigot or cylindrical hygiene body
US9044230B2 (en) 2012-02-13 2015-06-02 Ethicon Endo-Surgery, Inc. Surgical cutting and fastening instrument with apparatus for determining cartridge and firing motion status
US9757105B2 (en) 2012-03-23 2017-09-12 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
US8721680B2 (en) 2012-03-23 2014-05-13 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
MX353040B (en) 2012-03-28 2017-12-18 Ethicon Endo Surgery Inc Retainer assembly including a tissue thickness compensator.
BR112014024102B1 (en) 2012-03-28 2022-03-03 Ethicon Endo-Surgery, Inc CLAMP CARTRIDGE ASSEMBLY FOR A SURGICAL INSTRUMENT AND END ACTUATOR ASSEMBLY FOR A SURGICAL INSTRUMENT
CN104334098B (en) 2012-03-28 2017-03-22 伊西康内外科公司 Tissue thickness compensator comprising capsules defining a low pressure environment
US8444716B1 (en) 2012-05-23 2013-05-21 The Procter & Gamble Company Soluble solid hair coloring article
US9101358B2 (en) 2012-06-15 2015-08-11 Ethicon Endo-Surgery, Inc. Articulatable surgical instrument comprising a firing drive
US20140001234A1 (en) 2012-06-28 2014-01-02 Ethicon Endo-Surgery, Inc. Coupling arrangements for attaching surgical end effectors to drive systems therefor
US9289256B2 (en) 2012-06-28 2016-03-22 Ethicon Endo-Surgery, Llc Surgical end effectors having angled tissue-contacting surfaces
US9204879B2 (en) 2012-06-28 2015-12-08 Ethicon Endo-Surgery, Inc. Flexible drive member
US20140001231A1 (en) 2012-06-28 2014-01-02 Ethicon Endo-Surgery, Inc. Firing system lockout arrangements for surgical instruments
US11202631B2 (en) 2012-06-28 2021-12-21 Cilag Gmbh International Stapling assembly comprising a firing lockout
US9282974B2 (en) 2012-06-28 2016-03-15 Ethicon Endo-Surgery, Llc Empty clip cartridge lockout
BR112014032776B1 (en) 2012-06-28 2021-09-08 Ethicon Endo-Surgery, Inc SURGICAL INSTRUMENT SYSTEM AND SURGICAL KIT FOR USE WITH A SURGICAL INSTRUMENT SYSTEM
RU2636861C2 (en) 2012-06-28 2017-11-28 Этикон Эндо-Серджери, Инк. Blocking of empty cassette with clips
JP6158935B2 (en) 2012-10-12 2017-07-05 ザ プロクター アンド ギャンブル カンパニー Personal care composition in the form of a soluble article
WO2014059433A2 (en) 2012-10-12 2014-04-17 Mardil, Inc. Cardiac treatment system and method
JP6081156B2 (en) * 2012-11-15 2017-02-15 アルケア株式会社 Hydrogel
RU2669463C2 (en) 2013-03-01 2018-10-11 Этикон Эндо-Серджери, Инк. Surgical instrument with soft stop
RU2672520C2 (en) 2013-03-01 2018-11-15 Этикон Эндо-Серджери, Инк. Hingedly turnable surgical instruments with conducting ways for signal transfer
US10470762B2 (en) 2013-03-14 2019-11-12 Ethicon Llc Multi-function motor for a surgical instrument
US9629629B2 (en) 2013-03-14 2017-04-25 Ethicon Endo-Surgey, LLC Control systems for surgical instruments
US9649110B2 (en) 2013-04-16 2017-05-16 Ethicon Llc Surgical instrument comprising a closing drive and a firing drive operated from the same rotatable output
BR112015026109B1 (en) 2013-04-16 2022-02-22 Ethicon Endo-Surgery, Inc surgical instrument
US20150053737A1 (en) 2013-08-23 2015-02-26 Ethicon Endo-Surgery, Inc. End effector detection systems for surgical instruments
CN106028966B (en) 2013-08-23 2018-06-22 伊西康内外科有限责任公司 For the firing member restoring device of powered surgical instrument
USD717954S1 (en) 2013-10-14 2014-11-18 Mardil, Inc. Heart treatment device
US9962161B2 (en) 2014-02-12 2018-05-08 Ethicon Llc Deliverable surgical instrument
CN106232029B (en) 2014-02-24 2019-04-12 伊西康内外科有限责任公司 Fastening system including firing member locking piece
BR112016021943B1 (en) 2014-03-26 2022-06-14 Ethicon Endo-Surgery, Llc SURGICAL INSTRUMENT FOR USE BY AN OPERATOR IN A SURGICAL PROCEDURE
US9804618B2 (en) 2014-03-26 2017-10-31 Ethicon Llc Systems and methods for controlling a segmented circuit
US10004497B2 (en) 2014-03-26 2018-06-26 Ethicon Llc Interface systems for use with surgical instruments
US20150297222A1 (en) 2014-04-16 2015-10-22 Ethicon Endo-Surgery, Inc. Fastener cartridges including extensions having different configurations
JP6612256B2 (en) 2014-04-16 2019-11-27 エシコン エルエルシー Fastener cartridge with non-uniform fastener
US9844369B2 (en) 2014-04-16 2017-12-19 Ethicon Llc Surgical end effectors with firing element monitoring arrangements
BR112016023698B1 (en) 2014-04-16 2022-07-26 Ethicon Endo-Surgery, Llc FASTENER CARTRIDGE FOR USE WITH A SURGICAL INSTRUMENT
CN106456159B (en) 2014-04-16 2019-03-08 伊西康内外科有限责任公司 Fastener cartridge assembly and nail retainer lid arragement construction
US9801627B2 (en) 2014-09-26 2017-10-31 Ethicon Llc Fastener cartridge for creating a flexible staple line
JP6362226B2 (en) 2014-04-22 2018-07-25 ザ プロクター アンド ギャンブル カンパニー Composition in the form of a soluble solid structure
BR112017004361B1 (en) 2014-09-05 2023-04-11 Ethicon Llc ELECTRONIC SYSTEM FOR A SURGICAL INSTRUMENT
US10111679B2 (en) 2014-09-05 2018-10-30 Ethicon Llc Circuitry and sensors for powered medical device
US11311294B2 (en) 2014-09-05 2022-04-26 Cilag Gmbh International Powered medical device including measurement of closure state of jaws
US10105142B2 (en) 2014-09-18 2018-10-23 Ethicon Llc Surgical stapler with plurality of cutting elements
CN107427300B (en) 2014-09-26 2020-12-04 伊西康有限责任公司 Surgical suture buttress and buttress material
US11523821B2 (en) 2014-09-26 2022-12-13 Cilag Gmbh International Method for creating a flexible staple line
US10076325B2 (en) 2014-10-13 2018-09-18 Ethicon Llc Surgical stapling apparatus comprising a tissue stop
US9924944B2 (en) 2014-10-16 2018-03-27 Ethicon Llc Staple cartridge comprising an adjunct material
US11141153B2 (en) 2014-10-29 2021-10-12 Cilag Gmbh International Staple cartridges comprising driver arrangements
US10517594B2 (en) 2014-10-29 2019-12-31 Ethicon Llc Cartridge assemblies for surgical staplers
US9844376B2 (en) 2014-11-06 2017-12-19 Ethicon Llc Staple cartridge comprising a releasable adjunct material
US10736636B2 (en) 2014-12-10 2020-08-11 Ethicon Llc Articulatable surgical instrument system
US9844374B2 (en) 2014-12-18 2017-12-19 Ethicon Llc Surgical instrument systems comprising an articulatable end effector and means for adjusting the firing stroke of a firing member
US10085748B2 (en) 2014-12-18 2018-10-02 Ethicon Llc Locking arrangements for detachable shaft assemblies with articulatable surgical end effectors
RU2703684C2 (en) 2014-12-18 2019-10-21 ЭТИКОН ЭНДО-СЕРДЖЕРИ, ЭлЭлСи Surgical instrument with anvil which is selectively movable relative to staple cartridge around discrete fixed axis
US9943309B2 (en) 2014-12-18 2018-04-17 Ethicon Llc Surgical instruments with articulatable end effectors and movable firing beam support arrangements
US9987000B2 (en) 2014-12-18 2018-06-05 Ethicon Llc Surgical instrument assembly comprising a flexible articulation system
US9844375B2 (en) 2014-12-18 2017-12-19 Ethicon Llc Drive arrangements for articulatable surgical instruments
US11154301B2 (en) 2015-02-27 2021-10-26 Cilag Gmbh International Modular stapling assembly
US9931118B2 (en) 2015-02-27 2018-04-03 Ethicon Endo-Surgery, Llc Reinforced battery for a surgical instrument
US9808246B2 (en) 2015-03-06 2017-11-07 Ethicon Endo-Surgery, Llc Method of operating a powered surgical instrument
US10687806B2 (en) 2015-03-06 2020-06-23 Ethicon Llc Adaptive tissue compression techniques to adjust closure rates for multiple tissue types
US9901342B2 (en) 2015-03-06 2018-02-27 Ethicon Endo-Surgery, Llc Signal and power communication system positioned on a rotatable shaft
US10441279B2 (en) 2015-03-06 2019-10-15 Ethicon Llc Multiple level thresholds to modify operation of powered surgical instruments
US9924961B2 (en) 2015-03-06 2018-03-27 Ethicon Endo-Surgery, Llc Interactive feedback system for powered surgical instruments
US10617412B2 (en) 2015-03-06 2020-04-14 Ethicon Llc System for detecting the mis-insertion of a staple cartridge into a surgical stapler
JP2020121162A (en) 2015-03-06 2020-08-13 エシコン エルエルシーＥｔｈｉｃｏｎ ＬＬＣ Time dependent evaluation of sensor data to determine stability element, creep element and viscoelastic element of measurement
US10245033B2 (en) 2015-03-06 2019-04-02 Ethicon Llc Surgical instrument comprising a lockable battery housing
US10052044B2 (en) 2015-03-06 2018-08-21 Ethicon Llc Time dependent evaluation of sensor data to determine stability, creep, and viscoelastic elements of measures
US9993248B2 (en) 2015-03-06 2018-06-12 Ethicon Endo-Surgery, Llc Smart sensors with local signal processing
US10433844B2 (en) 2015-03-31 2019-10-08 Ethicon Llc Surgical instrument with selectively disengageable threaded drive systems
US11058425B2 (en) 2015-08-17 2021-07-13 Ethicon Llc Implantable layers for a surgical instrument
US10238386B2 (en) 2015-09-23 2019-03-26 Ethicon Llc Surgical stapler having motor control based on an electrical parameter related to a motor current
US10105139B2 (en) 2015-09-23 2018-10-23 Ethicon Llc Surgical stapler having downstream current-based motor control
US10363036B2 (en) 2015-09-23 2019-07-30 Ethicon Llc Surgical stapler having force-based motor control
US10327769B2 (en) 2015-09-23 2019-06-25 Ethicon Llc Surgical stapler having motor control based on a drive system component
US10299878B2 (en) 2015-09-25 2019-05-28 Ethicon Llc Implantable adjunct systems for determining adjunct skew
US10980539B2 (en) 2015-09-30 2021-04-20 Ethicon Llc Implantable adjunct comprising bonded layers
US11890015B2 (en) 2015-09-30 2024-02-06 Cilag Gmbh International Compressible adjunct with crossing spacer fibers
US20170086829A1 (en) 2015-09-30 2017-03-30 Ethicon Endo-Surgery, Llc Compressible adjunct with intermediate supporting structures
US10172620B2 (en) 2015-09-30 2019-01-08 Ethicon Llc Compressible adjuncts with bonding nodes
US10368865B2 (en) 2015-12-30 2019-08-06 Ethicon Llc Mechanisms for compensating for drivetrain failure in powered surgical instruments
US10265068B2 (en) 2015-12-30 2019-04-23 Ethicon Llc Surgical instruments with separable motors and motor control circuits
US10292704B2 (en) 2015-12-30 2019-05-21 Ethicon Llc Mechanisms for compensating for battery pack failure in powered surgical instruments
JP6911054B2 (en) 2016-02-09 2021-07-28 エシコン エルエルシーＥｔｈｉｃｏｎ ＬＬＣ Surgical instruments with asymmetric joint composition
US20170224332A1 (en) 2016-02-09 2017-08-10 Ethicon Endo-Surgery, Llc Surgical instruments with non-symmetrical articulation arrangements
US11213293B2 (en) 2016-02-09 2022-01-04 Cilag Gmbh International Articulatable surgical instruments with single articulation link arrangements
US10258331B2 (en) 2016-02-12 2019-04-16 Ethicon Llc Mechanisms for compensating for drivetrain failure in powered surgical instruments
US11224426B2 (en) 2016-02-12 2022-01-18 Cilag Gmbh International Mechanisms for compensating for drivetrain failure in powered surgical instruments
US10448948B2 (en) 2016-02-12 2019-10-22 Ethicon Llc Mechanisms for compensating for drivetrain failure in powered surgical instruments
US10617413B2 (en) 2016-04-01 2020-04-14 Ethicon Llc Closure system arrangements for surgical cutting and stapling devices with separate and distinct firing shafts
US10376263B2 (en) 2016-04-01 2019-08-13 Ethicon Llc Anvil modification members for surgical staplers
US10426467B2 (en) 2016-04-15 2019-10-01 Ethicon Llc Surgical instrument with detection sensors
US10357247B2 (en) 2016-04-15 2019-07-23 Ethicon Llc Surgical instrument with multiple program responses during a firing motion
US11607239B2 (en) 2016-04-15 2023-03-21 Cilag Gmbh International Systems and methods for controlling a surgical stapling and cutting instrument
US10492783B2 (en) 2016-04-15 2019-12-03 Ethicon, Llc Surgical instrument with improved stop/start control during a firing motion
US11179150B2 (en) 2016-04-15 2021-11-23 Cilag Gmbh International Systems and methods for controlling a surgical stapling and cutting instrument
US10828028B2 (en) 2016-04-15 2020-11-10 Ethicon Llc Surgical instrument with multiple program responses during a firing motion
US10405859B2 (en) 2016-04-15 2019-09-10 Ethicon Llc Surgical instrument with adjustable stop/start control during a firing motion
US10456137B2 (en) 2016-04-15 2019-10-29 Ethicon Llc Staple formation detection mechanisms
US10335145B2 (en) 2016-04-15 2019-07-02 Ethicon Llc Modular surgical instrument with configurable operating mode
US10478181B2 (en) 2016-04-18 2019-11-19 Ethicon Llc Cartridge lockout arrangements for rotary powered surgical cutting and stapling instruments
US11317917B2 (en) 2016-04-18 2022-05-03 Cilag Gmbh International Surgical stapling system comprising a lockable firing assembly
US20170296173A1 (en) 2016-04-18 2017-10-19 Ethicon Endo-Surgery, Llc Method for operating a surgical instrument
WO2018108256A1 (en) * 2016-12-13 2018-06-21 Stahl Kurt Wilhelm Composition for dressing cutaneous lesions and manufacturing method thereof
JP7010956B2 (en) 2016-12-21 2022-01-26 エシコン エルエルシー How to staple tissue
US10675026B2 (en) 2016-12-21 2020-06-09 Ethicon Llc Methods of stapling tissue
MX2019007311A (en) 2016-12-21 2019-11-18 Ethicon Llc Surgical stapling systems.
US11419606B2 (en) 2016-12-21 2022-08-23 Cilag Gmbh International Shaft assembly comprising a clutch configured to adapt the output of a rotary firing member to two different systems
US10736629B2 (en) 2016-12-21 2020-08-11 Ethicon Llc Surgical tool assemblies with clutching arrangements for shifting between closure systems with closure stroke reduction features and articulation and firing systems
US10639035B2 (en) 2016-12-21 2020-05-05 Ethicon Llc Surgical stapling instruments and replaceable tool assemblies thereof
US11191540B2 (en) 2016-12-21 2021-12-07 Cilag Gmbh International Protective cover arrangements for a joint interface between a movable jaw and actuator shaft of a surgical instrument
US10682138B2 (en) 2016-12-21 2020-06-16 Ethicon Llc Bilaterally asymmetric staple forming pocket pairs
US20180168615A1 (en) 2016-12-21 2018-06-21 Ethicon Endo-Surgery, Llc Method of deforming staples from two different types of staple cartridges with the same surgical stapling instrument
US10695055B2 (en) 2016-12-21 2020-06-30 Ethicon Llc Firing assembly comprising a lockout
US10492785B2 (en) 2016-12-21 2019-12-03 Ethicon Llc Shaft assembly comprising a lockout
US10881401B2 (en) 2016-12-21 2021-01-05 Ethicon Llc Staple firing member comprising a missing cartridge and/or spent cartridge lockout
US10835246B2 (en) 2016-12-21 2020-11-17 Ethicon Llc Staple cartridges and arrangements of staples and staple cavities therein
US10426471B2 (en) 2016-12-21 2019-10-01 Ethicon Llc Surgical instrument with multiple failure response modes
US10856868B2 (en) 2016-12-21 2020-12-08 Ethicon Llc Firing member pin configurations
US10448950B2 (en) 2016-12-21 2019-10-22 Ethicon Llc Surgical staplers with independently actuatable closing and firing systems
US11134942B2 (en) 2016-12-21 2021-10-05 Cilag Gmbh International Surgical stapling instruments and staple-forming anvils
JP6983893B2 (en) 2016-12-21 2021-12-17 エシコン エルエルシーEthicon LLC Lockout configuration for surgical end effectors and replaceable tool assemblies
US20180168625A1 (en) 2016-12-21 2018-06-21 Ethicon Endo-Surgery, Llc Surgical stapling instruments with smart staple cartridges
WO2018140675A1 (en) 2017-01-27 2018-08-02 The Procter & Gamble Company Compositions in the form of dissolvable solid structures comprising effervescent agglomerated particles
EP3573593B1 (en) 2017-01-27 2023-08-30 The Procter & Gamble Company Compositions in the form of dissolvable solid structures
JP6923673B2 (en) 2017-05-16 2021-08-25 ザ プロクター アンド ギャンブル カンパニーＴｈｅ Ｐｒｏｃｔｅｒ ＆ Ｇａｍｂｌｅ Ｃｏｍｐａｎｙ Conditioning hair care compositions in the form of soluble solid structures
US10327767B2 (en) 2017-06-20 2019-06-25 Ethicon Llc Control of motor velocity of a surgical stapling and cutting instrument based on angle of articulation
US10980537B2 (en) 2017-06-20 2021-04-20 Ethicon Llc Closed loop feedback control of motor velocity of a surgical stapling and cutting instrument based on measured time over a specified number of shaft rotations
US10624633B2 (en) 2017-06-20 2020-04-21 Ethicon Llc Systems and methods for controlling motor velocity of a surgical stapling and cutting instrument
US10307170B2 (en) 2017-06-20 2019-06-04 Ethicon Llc Method for closed loop control of motor velocity of a surgical stapling and cutting instrument
US11653914B2 (en) 2017-06-20 2023-05-23 Cilag Gmbh International Systems and methods for controlling motor velocity of a surgical stapling and cutting instrument according to articulation angle of end effector
US11517325B2 (en) 2017-06-20 2022-12-06 Cilag Gmbh International Closed loop feedback control of motor velocity of a surgical stapling and cutting instrument based on measured displacement distance traveled over a specified time interval
US10881396B2 (en) 2017-06-20 2021-01-05 Ethicon Llc Surgical instrument with variable duration trigger arrangement
US11071554B2 (en) 2017-06-20 2021-07-27 Cilag Gmbh International Closed loop feedback control of motor velocity of a surgical stapling and cutting instrument based on magnitude of velocity error measurements
US10881399B2 (en) 2017-06-20 2021-01-05 Ethicon Llc Techniques for adaptive control of motor velocity of a surgical stapling and cutting instrument
US10390841B2 (en) 2017-06-20 2019-08-27 Ethicon Llc Control of motor velocity of a surgical stapling and cutting instrument based on angle of articulation
US10813639B2 (en) 2017-06-20 2020-10-27 Ethicon Llc Closed loop feedback control of motor velocity of a surgical stapling and cutting instrument based on system conditions
USD879808S1 (en) 2017-06-20 2020-03-31 Ethicon Llc Display panel with graphical user interface
US11090046B2 (en) 2017-06-20 2021-08-17 Cilag Gmbh International Systems and methods for controlling displacement member motion of a surgical stapling and cutting instrument
US11382638B2 (en) 2017-06-20 2022-07-12 Cilag Gmbh International Closed loop feedback control of motor velocity of a surgical stapling and cutting instrument based on measured time over a specified displacement distance
US10646220B2 (en) 2017-06-20 2020-05-12 Ethicon Llc Systems and methods for controlling displacement member velocity for a surgical instrument
US10888321B2 (en) 2017-06-20 2021-01-12 Ethicon Llc Systems and methods for controlling velocity of a displacement member of a surgical stapling and cutting instrument
US10779820B2 (en) 2017-06-20 2020-09-22 Ethicon Llc Systems and methods for controlling motor speed according to user input for a surgical instrument
USD879809S1 (en) 2017-06-20 2020-03-31 Ethicon Llc Display panel with changeable graphical user interface
USD890784S1 (en) 2017-06-20 2020-07-21 Ethicon Llc Display panel with changeable graphical user interface
US10368864B2 (en) 2017-06-20 2019-08-06 Ethicon Llc Systems and methods for controlling displaying motor velocity for a surgical instrument
US11324503B2 (en) 2017-06-27 2022-05-10 Cilag Gmbh International Surgical firing member arrangements
US11141154B2 (en) 2017-06-27 2021-10-12 Cilag Gmbh International Surgical end effectors and anvils
US10993716B2 (en) 2017-06-27 2021-05-04 Ethicon Llc Surgical anvil arrangements
US11266405B2 (en) 2017-06-27 2022-03-08 Cilag Gmbh International Surgical anvil manufacturing methods
US10772629B2 (en) 2017-06-27 2020-09-15 Ethicon Llc Surgical anvil arrangements
US10856869B2 (en) 2017-06-27 2020-12-08 Ethicon Llc Surgical anvil arrangements
US10716614B2 (en) 2017-06-28 2020-07-21 Ethicon Llc Surgical shaft assemblies with slip ring assemblies with increased contact pressure
EP3420947B1 (en) 2017-06-28 2022-05-25 Cilag GmbH International Surgical instrument comprising selectively actuatable rotatable couplers
US11564686B2 (en) 2017-06-28 2023-01-31 Cilag Gmbh International Surgical shaft assemblies with flexible interfaces
USD869655S1 (en) 2017-06-28 2019-12-10 Ethicon Llc Surgical fastener cartridge
US11058424B2 (en) 2017-06-28 2021-07-13 Cilag Gmbh International Surgical instrument comprising an offset articulation joint
US10765427B2 (en) 2017-06-28 2020-09-08 Ethicon Llc Method for articulating a surgical instrument
US11478242B2 (en) 2017-06-28 2022-10-25 Cilag Gmbh International Jaw retainer arrangement for retaining a pivotable surgical instrument jaw in pivotable retaining engagement with a second surgical instrument jaw
USD851762S1 (en) 2017-06-28 2019-06-18 Ethicon Llc Anvil
USD854151S1 (en) 2017-06-28 2019-07-16 Ethicon Llc Surgical instrument shaft
US11259805B2 (en) 2017-06-28 2022-03-01 Cilag Gmbh International Surgical instrument comprising firing member supports
US11246592B2 (en) 2017-06-28 2022-02-15 Cilag Gmbh International Surgical instrument comprising an articulation system lockable to a frame
USD906355S1 (en) 2017-06-28 2020-12-29 Ethicon Llc Display screen or portion thereof with a graphical user interface for a surgical instrument
US10903685B2 (en) 2017-06-28 2021-01-26 Ethicon Llc Surgical shaft assemblies with slip ring assemblies forming capacitive channels
US10932772B2 (en) 2017-06-29 2021-03-02 Ethicon Llc Methods for closed loop velocity control for robotic surgical instrument
US10898183B2 (en) 2017-06-29 2021-01-26 Ethicon Llc Robotic surgical instrument with closed loop feedback techniques for advancement of closure member during firing
US10398434B2 (en) 2017-06-29 2019-09-03 Ethicon Llc Closed loop velocity control of closure member for robotic surgical instrument
US10258418B2 (en) 2017-06-29 2019-04-16 Ethicon Llc System for controlling articulation forces
US11007022B2 (en) 2017-06-29 2021-05-18 Ethicon Llc Closed loop velocity control techniques based on sensed tissue parameters for robotic surgical instrument
US11471155B2 (en) 2017-08-03 2022-10-18 Cilag Gmbh International Surgical system bailout
US11304695B2 (en) 2017-08-03 2022-04-19 Cilag Gmbh International Surgical system shaft interconnection
US11974742B2 (en) 2017-08-03 2024-05-07 Cilag Gmbh International Surgical system comprising an articulation bailout
US11944300B2 (en) 2017-08-03 2024-04-02 Cilag Gmbh International Method for operating a surgical system bailout
US11399829B2 (en) 2017-09-29 2022-08-02 Cilag Gmbh International Systems and methods of initiating a power shutdown mode for a surgical instrument
USD917500S1 (en) 2017-09-29 2021-04-27 Ethicon Llc Display screen or portion thereof with graphical user interface
US10796471B2 (en) 2017-09-29 2020-10-06 Ethicon Llc Systems and methods of displaying a knife position for a surgical instrument
USD907648S1 (en) 2017-09-29 2021-01-12 Ethicon Llc Display screen or portion thereof with animated graphical user interface
US10743872B2 (en) 2017-09-29 2020-08-18 Ethicon Llc System and methods for controlling a display of a surgical instrument
US10765429B2 (en) 2017-09-29 2020-09-08 Ethicon Llc Systems and methods for providing alerts according to the operational state of a surgical instrument
USD907647S1 (en) 2017-09-29 2021-01-12 Ethicon Llc Display screen or portion thereof with animated graphical user interface
US10729501B2 (en) 2017-09-29 2020-08-04 Ethicon Llc Systems and methods for language selection of a surgical instrument
US11090075B2 (en) 2017-10-30 2021-08-17 Cilag Gmbh International Articulation features for surgical end effector
US11134944B2 (en) 2017-10-30 2021-10-05 Cilag Gmbh International Surgical stapler knife motion controls
US10779903B2 (en) 2017-10-31 2020-09-22 Ethicon Llc Positive shaft rotation lock activated by jaw closure
US10842490B2 (en) 2017-10-31 2020-11-24 Ethicon Llc Cartridge body design with force reduction based on firing completion
US10687813B2 (en) 2017-12-15 2020-06-23 Ethicon Llc Adapters with firing stroke sensing arrangements for use in connection with electromechanical surgical instruments
US11197670B2 (en) 2017-12-15 2021-12-14 Cilag Gmbh International Surgical end effectors with pivotal jaws configured to touch at their respective distal ends when fully closed
US10779825B2 (en) 2017-12-15 2020-09-22 Ethicon Llc Adapters with end effector position sensing and control arrangements for use in connection with electromechanical surgical instruments
US10779826B2 (en) 2017-12-15 2020-09-22 Ethicon Llc Methods of operating surgical end effectors
US11033267B2 (en) 2017-12-15 2021-06-15 Ethicon Llc Systems and methods of controlling a clamping member firing rate of a surgical instrument
US11071543B2 (en) 2017-12-15 2021-07-27 Cilag Gmbh International Surgical end effectors with clamping assemblies configured to increase jaw aperture ranges
US10966718B2 (en) 2017-12-15 2021-04-06 Ethicon Llc Dynamic clamping assemblies with improved wear characteristics for use in connection with electromechanical surgical instruments
US10743875B2 (en) 2017-12-15 2020-08-18 Ethicon Llc Surgical end effectors with jaw stiffener arrangements configured to permit monitoring of firing member
US11006955B2 (en) 2017-12-15 2021-05-18 Ethicon Llc End effectors with positive jaw opening features for use with adapters for electromechanical surgical instruments
US10869666B2 (en) 2017-12-15 2020-12-22 Ethicon Llc Adapters with control systems for controlling multiple motors of an electromechanical surgical instrument
US10743874B2 (en) 2017-12-15 2020-08-18 Ethicon Llc Sealed adapters for use with electromechanical surgical instruments
US10828033B2 (en) 2017-12-15 2020-11-10 Ethicon Llc Handheld electromechanical surgical instruments with improved motor control arrangements for positioning components of an adapter coupled thereto
US10835330B2 (en) 2017-12-19 2020-11-17 Ethicon Llc Method for determining the position of a rotatable jaw of a surgical instrument attachment assembly
USD910847S1 (en) 2017-12-19 2021-02-16 Ethicon Llc Surgical instrument assembly
US11020112B2 (en) 2017-12-19 2021-06-01 Ethicon Llc Surgical tools configured for interchangeable use with different controller interfaces
US11045270B2 (en) 2017-12-19 2021-06-29 Cilag Gmbh International Robotic attachment comprising exterior drive actuator
US10729509B2 (en) 2017-12-19 2020-08-04 Ethicon Llc Surgical instrument comprising closure and firing locking mechanism
US10716565B2 (en) 2017-12-19 2020-07-21 Ethicon Llc Surgical instruments with dual articulation drivers
US11311290B2 (en) 2017-12-21 2022-04-26 Cilag Gmbh International Surgical instrument comprising an end effector dampener
US11076853B2 (en) 2017-12-21 2021-08-03 Cilag Gmbh International Systems and methods of displaying a knife position during transection for a surgical instrument
US11129680B2 (en) 2017-12-21 2021-09-28 Cilag Gmbh International Surgical instrument comprising a projector
US10743868B2 (en) 2017-12-21 2020-08-18 Ethicon Llc Surgical instrument comprising a pivotable distal head
KR102083002B1 (en) * 2018-03-30 2020-02-28 한양대학교 에리카산학협력단 Probiotics-loaded double-layered wound dressing and method for preparing the same
JP1639110S (en) 2018-07-16 2019-08-13
US11925660B2 (en) 2018-08-10 2024-03-12 Simeon Investment, Inc. Treatment for obesity with superabsorbent materials
US11918602B2 (en) 2018-08-10 2024-03-05 Simeon Investment, Inc. Methods for reducing cholesterol with superabsorbent materials
US11324501B2 (en) 2018-08-20 2022-05-10 Cilag Gmbh International Surgical stapling devices with improved closure members
US11045192B2 (en) 2018-08-20 2021-06-29 Cilag Gmbh International Fabricating techniques for surgical stapler anvils
US11039834B2 (en) 2018-08-20 2021-06-22 Cilag Gmbh International Surgical stapler anvils with staple directing protrusions and tissue stability features
USD914878S1 (en) 2018-08-20 2021-03-30 Ethicon Llc Surgical instrument anvil
US10842492B2 (en) 2018-08-20 2020-11-24 Ethicon Llc Powered articulatable surgical instruments with clutching and locking arrangements for linking an articulation drive system to a firing drive system
US11083458B2 (en) 2018-08-20 2021-08-10 Cilag Gmbh International Powered surgical instruments with clutching arrangements to convert linear drive motions to rotary drive motions
US11207065B2 (en) 2018-08-20 2021-12-28 Cilag Gmbh International Method for fabricating surgical stapler anvils
US11253256B2 (en) 2018-08-20 2022-02-22 Cilag Gmbh International Articulatable motor powered surgical instruments with dedicated articulation motor arrangements
US11291440B2 (en) 2018-08-20 2022-04-05 Cilag Gmbh International Method for operating a powered articulatable surgical instrument
US10912559B2 (en) 2018-08-20 2021-02-09 Ethicon Llc Reinforced deformable anvil tip for surgical stapler anvil
US10779821B2 (en) 2018-08-20 2020-09-22 Ethicon Llc Surgical stapler anvils with tissue stop features configured to avoid tissue pinch
US10856870B2 (en) 2018-08-20 2020-12-08 Ethicon Llc Switching arrangements for motor powered articulatable surgical instruments
US11666514B2 (en) 2018-09-21 2023-06-06 The Procter & Gamble Company Fibrous structures containing polymer matrix particles with perfume ingredients
CN109497634A (en) * 2018-11-21 2019-03-22 长沙浩然医疗科技有限公司 A kind of athletic undergarment that environmental protection care chest gas permeability stiff stability is high
USD918398S1 (en) 2018-12-10 2021-05-04 Johnson & Johnson Consumer Inc. Adhesive bandage with decorated pad
USD913507S1 (en) 2018-12-10 2021-03-16 Johnson & Johnson Consumer Inc. Adhesive bandage with decorated pad
US11147551B2 (en) 2019-03-25 2021-10-19 Cilag Gmbh International Firing drive arrangements for surgical systems
US11696761B2 (en) 2019-03-25 2023-07-11 Cilag Gmbh International Firing drive arrangements for surgical systems
US11147553B2 (en) 2019-03-25 2021-10-19 Cilag Gmbh International Firing drive arrangements for surgical systems
US11172929B2 (en) 2019-03-25 2021-11-16 Cilag Gmbh International Articulation drive arrangements for surgical systems
US11779683B2 (en) 2019-04-08 2023-10-10 Loubert S. Suddaby Extended release immunomodulatory implant to facilitate bone morphogenesis
US11369473B2 (en) 2019-04-08 2022-06-28 Loubert S. Suddaby Extended release immunomodulatory implant to facilitate bone morphogenesis
US11648009B2 (en) 2019-04-30 2023-05-16 Cilag Gmbh International Rotatable jaw tip for a surgical instrument
US11253254B2 (en) 2019-04-30 2022-02-22 Cilag Gmbh International Shaft rotation actuator on a surgical instrument
US11426251B2 (en) 2019-04-30 2022-08-30 Cilag Gmbh International Articulation directional lights on a surgical instrument
US11432816B2 (en) 2019-04-30 2022-09-06 Cilag Gmbh International Articulation pin for a surgical instrument
US11471157B2 (en) 2019-04-30 2022-10-18 Cilag Gmbh International Articulation control mapping for a surgical instrument
US11903581B2 (en) 2019-04-30 2024-02-20 Cilag Gmbh International Methods for stapling tissue using a surgical instrument
US11452528B2 (en) 2019-04-30 2022-09-27 Cilag Gmbh International Articulation actuators for a surgical instrument
US11298132B2 (en) 2019-06-28 2022-04-12 Cilag GmbH Inlernational Staple cartridge including a honeycomb extension
US11350938B2 (en) 2019-06-28 2022-06-07 Cilag Gmbh International Surgical instrument comprising an aligned rfid sensor
US11051807B2 (en) 2019-06-28 2021-07-06 Cilag Gmbh International Packaging assembly including a particulate trap
US11679066B2 (en) 2019-06-28 2023-06-20 The Procter & Gamble Company Dissolvable solid fibrous articles containing anionic surfactants
US11660163B2 (en) 2019-06-28 2023-05-30 Cilag Gmbh International Surgical system with RFID tags for updating motor assembly parameters
US11426167B2 (en) 2019-06-28 2022-08-30 Cilag Gmbh International Mechanisms for proper anvil attachment surgical stapling head assembly
US11684434B2 (en) 2019-06-28 2023-06-27 Cilag Gmbh International Surgical RFID assemblies for instrument operational setting control
US11478241B2 (en) 2019-06-28 2022-10-25 Cilag Gmbh International Staple cartridge including projections
US11553971B2 (en) 2019-06-28 2023-01-17 Cilag Gmbh International Surgical RFID assemblies for display and communication
US11771419B2 (en) 2019-06-28 2023-10-03 Cilag Gmbh International Packaging for a replaceable component of a surgical stapling system
US11246678B2 (en) 2019-06-28 2022-02-15 Cilag Gmbh International Surgical stapling system having a frangible RFID tag
US11497492B2 (en) 2019-06-28 2022-11-15 Cilag Gmbh International Surgical instrument including an articulation lock
US11627959B2 (en) 2019-06-28 2023-04-18 Cilag Gmbh International Surgical instruments including manual and powered system lockouts
US11638587B2 (en) 2019-06-28 2023-05-02 Cilag Gmbh International RFID identification systems for surgical instruments
US11464601B2 (en) 2019-06-28 2022-10-11 Cilag Gmbh International Surgical instrument comprising an RFID system for tracking a movable component
US11224497B2 (en) 2019-06-28 2022-01-18 Cilag Gmbh International Surgical systems with multiple RFID tags
US11259803B2 (en) 2019-06-28 2022-03-01 Cilag Gmbh International Surgical stapling system having an information encryption protocol
US11298127B2 (en) 2019-06-28 2022-04-12 Cilag GmbH Interational Surgical stapling system having a lockout mechanism for an incompatible cartridge
US11523822B2 (en) 2019-06-28 2022-12-13 Cilag Gmbh International Battery pack including a circuit interrupter
US11291451B2 (en) 2019-06-28 2022-04-05 Cilag Gmbh International Surgical instrument with battery compatibility verification functionality
US11399837B2 (en) 2019-06-28 2022-08-02 Cilag Gmbh International Mechanisms for motor control adjustments of a motorized surgical instrument
US11219455B2 (en) 2019-06-28 2022-01-11 Cilag Gmbh International Surgical instrument including a lockout key
US11376098B2 (en) 2019-06-28 2022-07-05 Cilag Gmbh International Surgical instrument system comprising an RFID system
EP3993757A1 (en) 2019-07-03 2022-05-11 The Procter & Gamble Company Fibrous structures containing cationic surfactants and soluble acids
US11135336B2 (en) 2019-09-30 2021-10-05 L'oreal Thin-film vehicles that stabilize highly reactive active ingredients
USD939359S1 (en) 2019-10-01 2021-12-28 The Procter And Gamble Plaza Packaging for a single dose personal care product
MX2022002875A (en) 2019-10-14 2022-03-25 Procter & Gamble Biodegradable and/or home compostable sachet containing a solid article.
CN114727933B (en) 2019-11-20 2024-03-08 宝洁公司 Porous dissolvable solid structure
WO2021113211A1 (en) 2019-12-01 2021-06-10 The Procter & Gamble Company Hair conditioner compositions with a preservation system containing sodium benzoate and glycols and/or glyceryl esters
US11844520B2 (en) 2019-12-19 2023-12-19 Cilag Gmbh International Staple cartridge comprising driver retention members
US11529137B2 (en) 2019-12-19 2022-12-20 Cilag Gmbh International Staple cartridge comprising driver retention members
US11911032B2 (en) 2019-12-19 2024-02-27 Cilag Gmbh International Staple cartridge comprising a seating cam
US11931033B2 (en) 2019-12-19 2024-03-19 Cilag Gmbh International Staple cartridge comprising a latch lockout
US11576672B2 (en) 2019-12-19 2023-02-14 Cilag Gmbh International Surgical instrument comprising a closure system including a closure member and an opening member driven by a drive screw
US11607219B2 (en) 2019-12-19 2023-03-21 Cilag Gmbh International Staple cartridge comprising a detachable tissue cutting knife
US11304696B2 (en) 2019-12-19 2022-04-19 Cilag Gmbh International Surgical instrument comprising a powered articulation system
US11701111B2 (en) 2019-12-19 2023-07-18 Cilag Gmbh International Method for operating a surgical stapling instrument
US11234698B2 (en) 2019-12-19 2022-02-01 Cilag Gmbh International Stapling system comprising a clamp lockout and a firing lockout
US11559304B2 (en) 2019-12-19 2023-01-24 Cilag Gmbh International Surgical instrument comprising a rapid closure mechanism
US11504122B2 (en) 2019-12-19 2022-11-22 Cilag Gmbh International Surgical instrument comprising a nested firing member
US11464512B2 (en) 2019-12-19 2022-10-11 Cilag Gmbh International Staple cartridge comprising a curved deck surface
US11291447B2 (en) 2019-12-19 2022-04-05 Cilag Gmbh International Stapling instrument comprising independent jaw closing and staple firing systems
US11529139B2 (en) 2019-12-19 2022-12-20 Cilag Gmbh International Motor driven surgical instrument
US11446029B2 (en) 2019-12-19 2022-09-20 Cilag Gmbh International Staple cartridge comprising projections extending from a curved deck surface
USD962050S1 (en) 2020-03-20 2022-08-30 The Procter And Gamble Company Primary package for a solid, single dose beauty care composition
USD941051S1 (en) 2020-03-20 2022-01-18 The Procter And Gamble Company Shower hanger
USD967421S1 (en) 2020-06-02 2022-10-18 Cilag Gmbh International Staple cartridge
USD976401S1 (en) 2020-06-02 2023-01-24 Cilag Gmbh International Staple cartridge
USD966512S1 (en) 2020-06-02 2022-10-11 Cilag Gmbh International Staple cartridge
USD975851S1 (en) 2020-06-02 2023-01-17 Cilag Gmbh International Staple cartridge
USD975850S1 (en) 2020-06-02 2023-01-17 Cilag Gmbh International Staple cartridge
USD975278S1 (en) 2020-06-02 2023-01-10 Cilag Gmbh International Staple cartridge
USD974560S1 (en) 2020-06-02 2023-01-03 Cilag Gmbh International Staple cartridge
USD965440S1 (en) 2020-06-29 2022-10-04 The Procter And Gamble Company Package
US11737748B2 (en) 2020-07-28 2023-08-29 Cilag Gmbh International Surgical instruments with double spherical articulation joints with pivotable links
JP2023534686A (en) 2020-07-31 2023-08-10 ザ プロクター アンド ギャンブル カンパニー Water-soluble fiber pouch containing prills for hair care
CN116456957A (en) 2020-08-11 2023-07-18 宝洁公司 Low viscosity hair conditioner compositions containing valine ester ethane sulfonate of brassinolide
EP4196234A1 (en) 2020-08-11 2023-06-21 The Procter & Gamble Company Clean rinse hair conditioner compositions containing brassicyl valinate esylate
JP2023537339A (en) 2020-08-11 2023-08-31 ザ プロクター アンド ギャンブル カンパニー Moisturizing hair conditioner composition containing brassy silver esylate
CA3191875A1 (en) 2020-09-10 2022-03-17 Ian-Ling Lim Dissolvable solid article containing anti-bacterial actives
US11617577B2 (en) 2020-10-29 2023-04-04 Cilag Gmbh International Surgical instrument comprising a sensor configured to sense whether an articulation drive of the surgical instrument is actuatable
USD980425S1 (en) 2020-10-29 2023-03-07 Cilag Gmbh International Surgical instrument assembly
USD1013170S1 (en) 2020-10-29 2024-01-30 Cilag Gmbh International Surgical instrument assembly
US11534259B2 (en) 2020-10-29 2022-12-27 Cilag Gmbh International Surgical instrument comprising an articulation indicator
US11717289B2 (en) 2020-10-29 2023-08-08 Cilag Gmbh International Surgical instrument comprising an indicator which indicates that an articulation drive is actuatable
US11844518B2 (en) 2020-10-29 2023-12-19 Cilag Gmbh International Method for operating a surgical instrument
US11452526B2 (en) 2020-10-29 2022-09-27 Cilag Gmbh International Surgical instrument comprising a staged voltage regulation start-up system
US11896217B2 (en) 2020-10-29 2024-02-13 Cilag Gmbh International Surgical instrument comprising an articulation lock
US11779330B2 (en) 2020-10-29 2023-10-10 Cilag Gmbh International Surgical instrument comprising a jaw alignment system
US11517390B2 (en) 2020-10-29 2022-12-06 Cilag Gmbh International Surgical instrument comprising a limited travel switch
US11931025B2 (en) 2020-10-29 2024-03-19 Cilag Gmbh International Surgical instrument comprising a releasable closure drive lock
CN116568266A (en) 2020-12-01 2023-08-08 宝洁公司 Aqueous hair conditioner composition containing dissolved anti-dandruff active
US11678882B2 (en) 2020-12-02 2023-06-20 Cilag Gmbh International Surgical instruments with interactive features to remedy incidental sled movements
US11890010B2 (en) 2020-12-02 2024-02-06 Cllag GmbH International Dual-sided reinforced reload for surgical instruments
US11653915B2 (en) 2020-12-02 2023-05-23 Cilag Gmbh International Surgical instruments with sled location detection and adjustment features
US11737751B2 (en) 2020-12-02 2023-08-29 Cilag Gmbh International Devices and methods of managing energy dissipated within sterile barriers of surgical instrument housings
US11744581B2 (en) 2020-12-02 2023-09-05 Cilag Gmbh International Powered surgical instruments with multi-phase tissue treatment
US11849943B2 (en) 2020-12-02 2023-12-26 Cilag Gmbh International Surgical instrument with cartridge release mechanisms
US11627960B2 (en) 2020-12-02 2023-04-18 Cilag Gmbh International Powered surgical instruments with smart reload with separately attachable exteriorly mounted wiring connections
US11653920B2 (en) 2020-12-02 2023-05-23 Cilag Gmbh International Powered surgical instruments with communication interfaces through sterile barrier
US11944296B2 (en) 2020-12-02 2024-04-02 Cilag Gmbh International Powered surgical instruments with external connectors
US11950779B2 (en) 2021-02-26 2024-04-09 Cilag Gmbh International Method of powering and communicating with a staple cartridge
US11980362B2 (en) 2021-02-26 2024-05-14 Cilag Gmbh International Surgical instrument system comprising a power transfer coil
US11793514B2 (en) 2021-02-26 2023-10-24 Cilag Gmbh International Staple cartridge comprising sensor array which may be embedded in cartridge body
US11701113B2 (en) 2021-02-26 2023-07-18 Cilag Gmbh International Stapling instrument comprising a separate power antenna and a data transfer antenna
US11749877B2 (en) 2021-02-26 2023-09-05 Cilag Gmbh International Stapling instrument comprising a signal antenna
US11730473B2 (en) 2021-02-26 2023-08-22 Cilag Gmbh International Monitoring of manufacturing life-cycle
US11812964B2 (en) 2021-02-26 2023-11-14 Cilag Gmbh International Staple cartridge comprising a power management circuit
US11723657B2 (en) 2021-02-26 2023-08-15 Cilag Gmbh International Adjustable communication based on available bandwidth and power capacity
US11950777B2 (en) 2021-02-26 2024-04-09 Cilag Gmbh International Staple cartridge comprising an information access control system
US11751869B2 (en) 2021-02-26 2023-09-12 Cilag Gmbh International Monitoring of multiple sensors over time to detect moving characteristics of tissue
US11744583B2 (en) 2021-02-26 2023-09-05 Cilag Gmbh International Distal communication array to tune frequency of RF systems
US11696757B2 (en) 2021-02-26 2023-07-11 Cilag Gmbh International Monitoring of internal systems to detect and track cartridge motion status
US11925349B2 (en) 2021-02-26 2024-03-12 Cilag Gmbh International Adjustment to transfer parameters to improve available power
US11826042B2 (en) 2021-03-22 2023-11-28 Cilag Gmbh International Surgical instrument comprising a firing drive including a selectable leverage mechanism
US11826012B2 (en) 2021-03-22 2023-11-28 Cilag Gmbh International Stapling instrument comprising a pulsed motor-driven firing rack
US11759202B2 (en) 2021-03-22 2023-09-19 Cilag Gmbh International Staple cartridge comprising an implantable layer
US11806011B2 (en) 2021-03-22 2023-11-07 Cilag Gmbh International Stapling instrument comprising tissue compression systems
US11717291B2 (en) 2021-03-22 2023-08-08 Cilag Gmbh International Staple cartridge comprising staples configured to apply different tissue compression
US11737749B2 (en) 2021-03-22 2023-08-29 Cilag Gmbh International Surgical stapling instrument comprising a retraction system
US11723658B2 (en) 2021-03-22 2023-08-15 Cilag Gmbh International Staple cartridge comprising a firing lockout
US11896219B2 (en) 2021-03-24 2024-02-13 Cilag Gmbh International Mating features between drivers and underside of a cartridge deck
US11896218B2 (en) 2021-03-24 2024-02-13 Cilag Gmbh International Method of using a powered stapling device
US11744603B2 (en) 2021-03-24 2023-09-05 Cilag Gmbh International Multi-axis pivot joints for surgical instruments and methods for manufacturing same
US11903582B2 (en) 2021-03-24 2024-02-20 Cilag Gmbh International Leveraging surfaces for cartridge installation
US11857183B2 (en) 2021-03-24 2024-01-02 Cilag Gmbh International Stapling assembly components having metal substrates and plastic bodies
US11793516B2 (en) 2021-03-24 2023-10-24 Cilag Gmbh International Surgical staple cartridge comprising longitudinal support beam
US11849944B2 (en) 2021-03-24 2023-12-26 Cilag Gmbh International Drivers for fastener cartridge assemblies having rotary drive screws
US11944336B2 (en) 2021-03-24 2024-04-02 Cilag Gmbh International Joint arrangements for multi-planar alignment and support of operational drive shafts in articulatable surgical instruments
US11786243B2 (en) 2021-03-24 2023-10-17 Cilag Gmbh International Firing members having flexible portions for adapting to a load during a surgical firing stroke
US11832816B2 (en) 2021-03-24 2023-12-05 Cilag Gmbh International Surgical stapling assembly comprising nonplanar staples and planar staples
US11786239B2 (en) 2021-03-24 2023-10-17 Cilag Gmbh International Surgical instrument articulation joint arrangements comprising multiple moving linkage features
US11849945B2 (en) 2021-03-24 2023-12-26 Cilag Gmbh International Rotary-driven surgical stapling assembly comprising eccentrically driven firing member
US20220378426A1 (en) 2021-05-28 2022-12-01 Cilag Gmbh International Stapling instrument comprising a mounted shaft orientation sensor
US11877745B2 (en) 2021-10-18 2024-01-23 Cilag Gmbh International Surgical stapling assembly having longitudinally-repeating staple leg clusters
US11980363B2 (en) 2021-10-18 2024-05-14 Cilag Gmbh International Row-to-row staple array variations
US11957337B2 (en) 2021-10-18 2024-04-16 Cilag Gmbh International Surgical stapling assembly with offset ramped drive surfaces
US11937816B2 (en) 2021-10-28 2024-03-26 Cilag Gmbh International Electrical lead arrangements for surgical instruments

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4002173A (en) * 1974-07-23 1977-01-11 International Paper Company Diester crosslinked polyglucan hydrogels and reticulated sponges thereof
US4333461A (en) * 1979-12-17 1982-06-08 Colgate-Palmolive Company Borated polysaccharide absorbents and absorbent products
US5118673A (en) * 1982-05-07 1992-06-02 Carrington Laboratories, Inc. Uses of aloe products
US4851224A (en) * 1986-06-05 1989-07-25 Carrington Laboratories, Inc. Process for preparation of aloe products
US5106616A (en) * 1988-01-14 1992-04-21 Carrington Laboratories, Inc. Administration of acemannan
SE8501022L (en) * 1985-03-01 1986-09-02 Pharmacia Ab FORMAT CREATES AND PROCEDURES FOR ITS PREPARATION
WO1987000052A1 (en) * 1985-06-28 1987-01-15 Carrington Laboratories, Inc. Processes for preparation of aloe products, products produced thereby and compositions thereof
US5079018A (en) * 1989-08-14 1992-01-07 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
EP0625894A1 (en) * 1991-10-09 1994-11-30 LecTec Corporation Aqueous gel wound dressing and package
GB9209327D0 (en) * 1992-04-30 1992-06-17 Johnson & Johnson Medical Freeze-dried pad

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