WO1994023027A3 - Gene vegetal specifiant la carboxylase du coenzyme a d'acetyle, et plantes transformees contenant ce gene - Google Patents

Gene vegetal specifiant la carboxylase du coenzyme a d'acetyle, et plantes transformees contenant ce gene Download PDF

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Publication number
WO1994023027A3
WO1994023027A3 PCT/GB1994/000653 GB9400653W WO9423027A3 WO 1994023027 A3 WO1994023027 A3 WO 1994023027A3 GB 9400653 W GB9400653 W GB 9400653W WO 9423027 A3 WO9423027 A3 WO 9423027A3
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WIPO (PCT)
Prior art keywords
acetyl coenzyme
carboxylase
transformed plants
plants containing
containing same
Prior art date
Application number
PCT/GB1994/000653
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English (en)
Other versions
WO1994023027A2 (fr
Inventor
Anthony Rysard Slabas
Keiran Michael Elborough
Simon William Jonathan Bright
Philip Antony Fentem
Original Assignee
Zeneca Ltd
Anthony Rysard Slabas
Keiran Michael Elborough
Simon William Jonathan Bright
Philip Antony Fentem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd, Anthony Rysard Slabas, Keiran Michael Elborough, Simon William Jonathan Bright, Philip Antony Fentem filed Critical Zeneca Ltd
Priority to AU64331/94A priority Critical patent/AU6433194A/en
Publication of WO1994023027A2 publication Critical patent/WO1994023027A2/fr
Publication of WO1994023027A3 publication Critical patent/WO1994023027A3/fr

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Des séquences d'ADN d'une carboxylase du coenzyme A d'acétyle ACCase issue de plantes sont insérées dans le génome de plantes avec une orientation sens ou antisens afin d'inhiber l'expression du produit génique du gène ACCase endogène, entraînant une réduction de la conversion du substrat de l'enzyme, le coenzyme A d'acétyle, en synthèse d'acide gras, laissant le substrat disponible pour une diversion dans d'autres processus de biosynthèse. On peut effectuer une telle diversion en munissant le génome d'une plante de gènes spécifiant la synthèse de polymères de polyhydroxyalcanoate.
PCT/GB1994/000653 1993-03-29 1994-03-29 Gene vegetal specifiant la carboxylase du coenzyme a d'acetyle, et plantes transformees contenant ce gene WO1994023027A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU64331/94A AU6433194A (en) 1993-03-29 1994-03-29 Plant gene specifying acetyl coenzyme a carboxylase and transformed plants containing same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939306490A GB9306490D0 (en) 1993-03-29 1993-03-29 Plant gene specifying acetyl,coenzyme a carboxylase and transformed plants containing same
GB9306490.5 1993-03-29

Publications (2)

Publication Number Publication Date
WO1994023027A2 WO1994023027A2 (fr) 1994-10-13
WO1994023027A3 true WO1994023027A3 (fr) 1995-05-26

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1994/000653 WO1994023027A2 (fr) 1993-03-29 1994-03-29 Gene vegetal specifiant la carboxylase du coenzyme a d'acetyle, et plantes transformees contenant ce gene

Country Status (3)

Country Link
AU (1) AU6433194A (fr)
GB (1) GB9306490D0 (fr)
WO (1) WO1994023027A2 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5245023A (en) 1987-06-29 1993-09-14 Massachusetts Institute Of Technology Method for producing novel polyester biopolymers
JP3696233B2 (ja) * 1991-07-19 2005-09-14 ミシガン、ステート、ユニバーシティー ポリヒドロキシアルカノエートを生産するトランスジェニック植物
US5610041A (en) * 1991-07-19 1997-03-11 Board Of Trustees Operating Michigan State University Processes for producing polyhydroxybutyrate and related polyhydroxyalkanoates in the plastids of higher plants
US5539092A (en) * 1992-10-02 1996-07-23 Arch Development Corporation Cyanobacterial and plant acetyl-CoA carboxylase
US6414222B1 (en) 1993-02-05 2002-07-02 Regents Of The University Of Minnesota Gene combinations for herbicide tolerance in corn
US6222099B1 (en) 1993-02-05 2001-04-24 Regents Of The University Of Minnesota Transgenic plants expressing maize acetyl COA carboxylase gene and method of altering oil content
US6069298A (en) * 1993-02-05 2000-05-30 Regents Of The University Of Minnesota Methods and an acetyl CoA carboxylase gene for conferring herbicide tolerance and an alteration in oil content of plants
EP0716707A1 (fr) * 1993-09-04 1996-06-19 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Promoteurs
WO1995029246A1 (fr) * 1994-04-21 1995-11-02 Zeneca Limited Gene vegetal specifiant l'acetyl-coenzyme a-carboxylase et plantes transformees contenant ce gene
US5925805A (en) * 1994-05-24 1999-07-20 Board Of Trustees Operating Michigan State University Methods of increasing oil content of seeds
US5962767A (en) * 1994-05-24 1999-10-05 Board Of Trustees Operating Michigan State University Structure and expression of an arabidopsis acetyl-coenzyme A carboxylase gene
CA2218139A1 (fr) * 1995-04-14 1996-10-17 Arch Development Corporation Compositions a base d'acetyl-coa carboxylase et procedes d'utilisation
US6083729A (en) * 1995-10-26 2000-07-04 Metabolix, Inc. Methods for isolating polyhydroxyalkanoates from plants
US6306636B1 (en) 1997-09-19 2001-10-23 Arch Development Corporation Nucleic acid segments encoding wheat acetyl-CoA carboxylase
EP1060250A1 (fr) * 1998-03-06 2000-12-20 Metabolix, Inc. Modification du metabolisme des acides gras dans des plantes
US6586658B1 (en) 1998-03-06 2003-07-01 Metabolix, Inc. Modification of fatty acid metabolism in plants
CN116121294A (zh) 2015-08-28 2023-05-16 密苏里大学管理者 通过改变乙酰-coa羧化酶的负调控因子来增加植物油含量
US11802286B2 (en) 2016-07-07 2023-10-31 The Curators Of The University Of Missouri Increasing plant oil content by improving activity of acetyl-CoA carboxylase
CN118127069A (zh) * 2024-04-01 2024-06-04 安阳工学院 GhBC1基因在调控植物种子粒重、宽度以及育种中的应用

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0255378A2 (fr) * 1986-07-31 1988-02-03 Calgene, Inc. Régulation de transcription spécifique pour des graines
EP0469810A1 (fr) * 1990-07-30 1992-02-05 Iowa State University Research Foundation, Inc. Polypeptide et gène de acétyl-CoA carboxylase de plantes
US5162602A (en) * 1988-11-10 1992-11-10 Regents Of The University Of Minnesota Corn plants tolerant to sethoxydim and haloxyfop herbicides
WO1993011243A1 (fr) * 1991-11-28 1993-06-10 Ici Australia Operations Proprietary Limited CLONES D'ADN CODANT POUR LA CARBOXYLASE CoA D'ACETYLE DE MAIS
WO1994008016A1 (fr) * 1992-10-02 1994-04-14 Arch Development Corporation ACETYL-CoA CARBOXYLASE VEGETALE ET CYANOBACTERIENNE
WO1994017188A2 (fr) * 1993-01-22 1994-08-04 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Gene acetyl-coa-carboxylase

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0255378A2 (fr) * 1986-07-31 1988-02-03 Calgene, Inc. Régulation de transcription spécifique pour des graines
US5162602A (en) * 1988-11-10 1992-11-10 Regents Of The University Of Minnesota Corn plants tolerant to sethoxydim and haloxyfop herbicides
EP0469810A1 (fr) * 1990-07-30 1992-02-05 Iowa State University Research Foundation, Inc. Polypeptide et gène de acétyl-CoA carboxylase de plantes
WO1993011243A1 (fr) * 1991-11-28 1993-06-10 Ici Australia Operations Proprietary Limited CLONES D'ADN CODANT POUR LA CARBOXYLASE CoA D'ACETYLE DE MAIS
WO1994008016A1 (fr) * 1992-10-02 1994-04-14 Arch Development Corporation ACETYL-CoA CARBOXYLASE VEGETALE ET CYANOBACTERIENNE
WO1994017188A2 (fr) * 1993-01-22 1994-08-04 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Gene acetyl-coa-carboxylase

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
ARCH. BIOCHEM. BIOPHYS., vol. 203, no. 1, 1980, pages 90 - 100 *
BIOLOGICAL ABSTRACTS, vol. 71, 1981, Philadelphia, PA, US; abstract no. 5758, EGIN-BUEHLER, B., ET AL.: "Comparison of acetyl coenzyme A carboxylases (EC 6.4.1.2) from parsley (Petroselinum hortense) cell cultures and wheat germ" *
BIOLOGICAL ABSTRACTS, vol. 80, Philadelphia, PA, US; abstract no. 99052, SLABAS, A.R., ET AL.: "Rapid purification of a high-molecular-weight subunit polypeptide form of rape Brassica-napus cultivar jet-neuf seed acetyl coenzyme A carboxylase" *
ELBOROUGH, K.M., ET AL.: "Regulation of primary storage products of oil seeds by manipulating the levels of the genes involved in lipid metabolism on plant acetyl CoA carboxylase", J. CELL BIOCHEM. SUPPL., vol. 18A, 1994 *
ELBOROUGH, K.M., ET AL.: "Studies on wheat acetyl CoA carboxylase and the cloning of a partial cDNA", PLANT MOLECULAR BIOLOGY., vol. 24, no. 1, January 1994 (1994-01-01), DORDRECHT, THE NETHERLANDS., pages 21 - 34 *
KEYSTONE SYMPOSIUM ON IMPROVED CROP AND PLANT PRODUCTS THROUGH BIOTECHNOLOGY, HELD, JAN. 9-16, 1994. *
LI,S.J., ET AL.: "Putative zinc finger protein encoded by a conserved chloroplast gene is very likely a subunit of a biotin-dependant carboxylase", PLANT MOLECULAR BIOLOGY, vol. 20, 1992, pages 759 - 761 *
PLANT SCIENCE, vol. 39, no. 3, 1985, pages 177 - 182 *
SCHULTE, W., ET AL.: "Strategies for the isolation of genes involved in de-novo fatty acid biosynthesis", J. CELL. BIOCHEM. SUPPL., vol. 16F, 1992, pages 227 *

Also Published As

Publication number Publication date
WO1994023027A2 (fr) 1994-10-13
GB9306490D0 (en) 1993-05-19
AU6433194A (en) 1994-10-24

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