WO1994011505A1 - Polypeptides specifiques de pars planitis - Google Patents

Polypeptides specifiques de pars planitis Download PDF

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Publication number
WO1994011505A1
WO1994011505A1 PCT/US1993/010825 US9310825W WO9411505A1 WO 1994011505 A1 WO1994011505 A1 WO 1994011505A1 US 9310825 W US9310825 W US 9310825W WO 9411505 A1 WO9411505 A1 WO 9411505A1
Authority
WO
WIPO (PCT)
Prior art keywords
antibody
sequence
cells
expression vector
cell
Prior art date
Application number
PCT/US1993/010825
Other languages
English (en)
Inventor
Nalini S. Bora
Henry J. Kaplan
Original Assignee
Washington University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Washington University filed Critical Washington University
Priority to AU58963/94A priority Critical patent/AU5896394A/en
Publication of WO1994011505A1 publication Critical patent/WO1994011505A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Nouvelle protéine circulante spécifique de pars planitis, appelée P-36, présentant une masse moléculaire d'approximativement 36 kilodaltons. On a cloné le gène d'ADNc codant la P-36, et on a déterminé le nucléotide ansi que des séquences d'acides aminés déduites. L'invention concerne également des vecteurs et des systèmes d'expression de la P-36 recombinée. En outre, l'invention concerne des anticorps contre la P-36 ainsi que leur usage dans des immunodosages de la protéine, et un procédé de diagnostic de pars planitis chez un patient par détermination de la présence de la P-36 dans la circulation sanguine.
PCT/US1993/010825 1992-11-10 1993-11-10 Polypeptides specifiques de pars planitis WO1994011505A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU58963/94A AU5896394A (en) 1992-11-10 1993-11-10 Pars planitis specific polypeptides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97770992A 1992-11-10 1992-11-10
US07/977,709 1992-11-10

Publications (1)

Publication Number Publication Date
WO1994011505A1 true WO1994011505A1 (fr) 1994-05-26

Family

ID=25525435

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1993/010825 WO1994011505A1 (fr) 1992-11-10 1993-11-10 Polypeptides specifiques de pars planitis

Country Status (2)

Country Link
AU (1) AU5896394A (fr)
WO (1) WO1994011505A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5795872A (en) * 1995-09-19 1998-08-18 Pharmadigm, Inc. DNA construct for immunization
US5834235A (en) * 1996-06-21 1998-11-10 Health Research, Incorporated Inferferon-α-induced protein
US7531504B2 (en) * 1998-08-03 2009-05-12 University Of Maryland, Baltimore Pharmaceutical composition and method for inhibiting gastrointestinal inflammation

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
E. HARLOW et al., "Antibodies, a Laboratory Manual", published 1988, by COLD SPRING HARBOR LABORATORY (COLD SPRING HARBOR), see pages 553-612. *
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Volume 32, No. 4, issued March 1991, N.S. BORA et al., "Identification of a Novel Circulating Protein (P-35) in Patients with Pars Planitis", page 940, Abstract No. 1335-73. *
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Volume 33, No. 4, issued 15 March 1992, J.B. FLEISCHMAN et al., "P-36. A Novel Circulating Protein; its Identification and Correlation with Active Pars Planitis", page 930, Abstract No. 1190-5. *
J. SAMBROOK et al., "Molecular Cloning, a Laboratory Manual", published 1989, by COLD SPRING HARBOR LABORATORY, see pages 11.1-11.61, 16.1-16.81 and 17.1-17.44. *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5795872A (en) * 1995-09-19 1998-08-18 Pharmadigm, Inc. DNA construct for immunization
US5834235A (en) * 1996-06-21 1998-11-10 Health Research, Incorporated Inferferon-α-induced protein
US6060279A (en) * 1996-06-21 2000-05-09 Health Research, Incorporated Interferon-α-induced protein
US7531504B2 (en) * 1998-08-03 2009-05-12 University Of Maryland, Baltimore Pharmaceutical composition and method for inhibiting gastrointestinal inflammation

Also Published As

Publication number Publication date
AU5896394A (en) 1994-06-08

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