WO1994000602A1 - Procede et dispositif de detection et de quantification de substances dans des liquides organiques - Google Patents

Procede et dispositif de detection et de quantification de substances dans des liquides organiques Download PDF

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Publication number
WO1994000602A1
WO1994000602A1 PCT/US1993/006131 US9306131W WO9400602A1 WO 1994000602 A1 WO1994000602 A1 WO 1994000602A1 US 9306131 W US9306131 W US 9306131W WO 9400602 A1 WO9400602 A1 WO 9400602A1
Authority
WO
WIPO (PCT)
Prior art keywords
fluorescence
analyte
donor
sensor
acceptor
Prior art date
Application number
PCT/US1993/006131
Other languages
English (en)
Inventor
William L. Chick
David E. Wolf
Richard A. Cardullo
Original Assignee
Sensor Technologies, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sensor Technologies, Inc. filed Critical Sensor Technologies, Inc.
Priority to EP93916805A priority Critical patent/EP0649476A4/fr
Publication of WO1994000602A1 publication Critical patent/WO1994000602A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

Procédé et dispositif servant à détecter in vivo la présence d'un analyte chez un individu. Un détecteur comprenant un réactif à fluorescence est mis en communication avec les liquides organiques de l'individu susceptible de contenir l'analyte, de façon qu'il ne puisse pas sortir de l'épiderme de l'individu une fois qu'il est positionné. Le détecteur est conçu pour retenir le réactif à fluorescence tout en permettant à l'analyte de se diffuser vers l'intérieur et vers l'extérieur dudit détecteur. On éclaire le détecteur intradermiquement et on mesure la fluorescence émise par le réactif et associée à la présence de l'analyte.
PCT/US1993/006131 1992-06-29 1993-06-28 Procede et dispositif de detection et de quantification de substances dans des liquides organiques WO1994000602A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP93916805A EP0649476A4 (fr) 1992-06-29 1993-06-28 Procede et dispositif de detection et de quantification de substances dans des liquides organiques.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90572992A 1992-06-29 1992-06-29
US07/905,729 1992-06-29

Publications (1)

Publication Number Publication Date
WO1994000602A1 true WO1994000602A1 (fr) 1994-01-06

Family

ID=25421368

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1993/006131 WO1994000602A1 (fr) 1992-06-29 1993-06-28 Procede et dispositif de detection et de quantification de substances dans des liquides organiques

Country Status (2)

Country Link
EP (1) EP0649476A4 (fr)
WO (1) WO1994000602A1 (fr)

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998007364A1 (fr) * 1996-08-16 1998-02-26 Roche Diagnostics Gmbh Systeme de controle pour la prise reguliere d'un medicament
WO1998055869A1 (fr) * 1997-06-04 1998-12-10 Sensor Technologies, Inc. Procede et dispositif de detection ou d'evaluation de composes contenant des glucides
WO2000002048A1 (fr) * 1998-07-03 2000-01-13 Torsana Diabetes Diagnostics A/S DETECTEUR OPTIQUE PERMETTANT LA MESURE D'ANALYTES $i(IN SITU)
EP0987985A1 (fr) * 1997-06-05 2000-03-29 Kairos Scientific Inc. Etalonnage du transfert d'energie de resonance par fluorescence en microscopie
US6136274A (en) * 1996-10-07 2000-10-24 Irori Matrices with memories in automated drug discovery and units therefor
US6625479B1 (en) 1998-07-03 2003-09-23 Torsana Diabetes Diagnostics A/S Optical sensor for in situ measurement of analytes
USRE38525E1 (en) 1998-07-03 2004-06-08 Torsana Diabetes Diagnostics A/S Optical sensor for in situ measurement of analytes
WO2009015870A1 (fr) 2007-08-01 2009-02-05 Roche Diagnostics Gmbh Procédé et dispositif pour déterminer la concentration d'un analyte par mesure de la fluorescence
US7619072B2 (en) 2003-11-21 2009-11-17 Uws Ventures Limited Purification method for recombinant glucose binding protein
US8180421B2 (en) 2007-12-12 2012-05-15 Kimberly-Clark Worldwide, Inc. Resonance energy transfer based detection of nosocomial infection
WO2012104411A1 (fr) * 2011-02-03 2012-08-09 Institut National De La Sante Et De La Recherche Medicale (Inserm) Marquage des lipoprotéines, procédés pour suivre le transport/l'évolution des lipoprotéines et pour dépister les troubles dyslipidémiques
CN102939539A (zh) * 2010-02-19 2013-02-20 灯船医药有限公司 皮下葡萄糖传感器
EP2620507A1 (fr) 2012-01-25 2013-07-31 Roche Diagnostics GmbH Procédé pour l'évaluation de la qualité d'un élément de test
US9037205B2 (en) 2011-06-30 2015-05-19 Glusense, Ltd Implantable optical glucose sensing
DE102005056310B4 (de) * 2005-11-25 2017-02-02 Drägerwerk AG & Co. KGaA Verfahren und Vorrichtung zur Überwachung von Infusionen
CN109490274A (zh) * 2019-01-04 2019-03-19 齐鲁工业大学 一种用于研究酶在皮革中单向传质的实验装置及使用方法
US10575765B2 (en) 2014-10-13 2020-03-03 Glusense Ltd. Analyte-sensing device
US10871487B2 (en) 2016-04-20 2020-12-22 Glusense Ltd. FRET-based glucose-detection molecules

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4330299A (en) * 1981-03-09 1982-05-18 Evreka, Inc. Article and method for measuring glucose level in body fluids
US4401122A (en) * 1979-08-02 1983-08-30 Children's Hospital Medical Center Cutaneous methods of measuring body substances
US5143066A (en) * 1990-05-08 1992-09-01 University Of Pittsburgh Optical fiber sensors for continuous monitoring of biochemicals and related method

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342789A (en) 1989-12-14 1994-08-30 Sensor Technologies, Inc. Method and device for detecting and quantifying glucose in body fluids
EP0447949A1 (fr) * 1990-03-22 1991-09-25 F. Hoffmann-La Roche Ag Détecteur optique d'oxygène
US5246867A (en) * 1992-01-17 1993-09-21 University Of Maryland At Baltimore Determination and quantification of saccharides by luminescence lifetimes and energy transfer

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4401122A (en) * 1979-08-02 1983-08-30 Children's Hospital Medical Center Cutaneous methods of measuring body substances
US4330299A (en) * 1981-03-09 1982-05-18 Evreka, Inc. Article and method for measuring glucose level in body fluids
US5143066A (en) * 1990-05-08 1992-09-01 University Of Pittsburgh Optical fiber sensors for continuous monitoring of biochemicals and related method

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Proceedings of the National Academy of Sciences, United States of America, Volume 85, Number 23, issued December 1988, R.A. CARDULLO et al., "Detection of Nucleic Acid Hybridization by Nonradioactive Fluorescence Resonance Energy Transfer", pages 8790-8794, see entire document. *
Rapid Detection and Identification of Infectious Agents", issued 1985, M.J. HELLER et al., "Chemiluminscent and Fluorescent Probes for DNA Hybridization Systems", pages 245-256, see entire document. *
See also references of EP0649476A1 *
Talanta, Volume 35, Number 2, issued 1988, D. MEADOWS et al., "Fiber-Optic Bisensors Based on Fluorescence Energy Transfer", pages 145-150, see entire document. *

Cited By (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998007364A1 (fr) * 1996-08-16 1998-02-26 Roche Diagnostics Gmbh Systeme de controle pour la prise reguliere d'un medicament
US6136274A (en) * 1996-10-07 2000-10-24 Irori Matrices with memories in automated drug discovery and units therefor
WO1998055869A1 (fr) * 1997-06-04 1998-12-10 Sensor Technologies, Inc. Procede et dispositif de detection ou d'evaluation de composes contenant des glucides
US6232130B1 (en) 1997-06-04 2001-05-15 Sensor Technologies, Inc. Method for detecting or quantifying carbohydrate containing compounds
EP0987985A1 (fr) * 1997-06-05 2000-03-29 Kairos Scientific Inc. Etalonnage du transfert d'energie de resonance par fluorescence en microscopie
EP0987985A4 (fr) * 1997-06-05 2009-04-29 Kairos Scient Inc Etalonnage du transfert d'energie de resonance par fluorescence en microscopie
US6163714A (en) * 1998-07-03 2000-12-19 Torsana Diabetes Diagnostics A/S Optical sensor for in situ measurement of analytes
US6625479B1 (en) 1998-07-03 2003-09-23 Torsana Diabetes Diagnostics A/S Optical sensor for in situ measurement of analytes
USRE38525E1 (en) 1998-07-03 2004-06-08 Torsana Diabetes Diagnostics A/S Optical sensor for in situ measurement of analytes
EP1542014A1 (fr) * 1998-07-03 2005-06-15 Precisense A/S Capteur optique pour la mesure in situ d'analytes
WO2000002048A1 (fr) * 1998-07-03 2000-01-13 Torsana Diabetes Diagnostics A/S DETECTEUR OPTIQUE PERMETTANT LA MESURE D'ANALYTES $i(IN SITU)
US7619072B2 (en) 2003-11-21 2009-11-17 Uws Ventures Limited Purification method for recombinant glucose binding protein
DE102005056310B4 (de) * 2005-11-25 2017-02-02 Drägerwerk AG & Co. KGaA Verfahren und Vorrichtung zur Überwachung von Infusionen
WO2009015870A1 (fr) 2007-08-01 2009-02-05 Roche Diagnostics Gmbh Procédé et dispositif pour déterminer la concentration d'un analyte par mesure de la fluorescence
US8180421B2 (en) 2007-12-12 2012-05-15 Kimberly-Clark Worldwide, Inc. Resonance energy transfer based detection of nosocomial infection
CN102939539A (zh) * 2010-02-19 2013-02-20 灯船医药有限公司 皮下葡萄糖传感器
WO2012104411A1 (fr) * 2011-02-03 2012-08-09 Institut National De La Sante Et De La Recherche Medicale (Inserm) Marquage des lipoprotéines, procédés pour suivre le transport/l'évolution des lipoprotéines et pour dépister les troubles dyslipidémiques
US9037205B2 (en) 2011-06-30 2015-05-19 Glusense, Ltd Implantable optical glucose sensing
EP2620507A1 (fr) 2012-01-25 2013-07-31 Roche Diagnostics GmbH Procédé pour l'évaluation de la qualité d'un élément de test
WO2013110453A1 (fr) 2012-01-25 2013-08-01 Roche Diagnostics Gmbh Procédé pour l'évaluation de la qualité d'un élément de test
US10575765B2 (en) 2014-10-13 2020-03-03 Glusense Ltd. Analyte-sensing device
US10871487B2 (en) 2016-04-20 2020-12-22 Glusense Ltd. FRET-based glucose-detection molecules
CN109490274A (zh) * 2019-01-04 2019-03-19 齐鲁工业大学 一种用于研究酶在皮革中单向传质的实验装置及使用方法

Also Published As

Publication number Publication date
EP0649476A1 (fr) 1995-04-26
EP0649476A4 (fr) 1997-05-07

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