WO1992021358A1 - Liniment - Google Patents

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Publication number
WO1992021358A1
WO1992021358A1 PCT/EP1992/001236 EP9201236W WO9221358A1 WO 1992021358 A1 WO1992021358 A1 WO 1992021358A1 EP 9201236 W EP9201236 W EP 9201236W WO 9221358 A1 WO9221358 A1 WO 9221358A1
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WO
WIPO (PCT)
Prior art keywords
toning agent
camphor
myrrh
oil
agent according
Prior art date
Application number
PCT/EP1992/001236
Other languages
German (de)
French (fr)
Inventor
Marianne Seiler
Original Assignee
Marianne Seiler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marianne Seiler filed Critical Marianne Seiler
Publication of WO1992021358A1 publication Critical patent/WO1992021358A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238—Saposhnikovia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/52—Juglandaceae (Walnut family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon

Definitions

  • the invention relates to a toning agent for topical application on a purely vegetable basis.
  • medicinal healing ointments which, from natural fats (of animal or vegetable origin), alcohol, bee honey, yeast (all types), the active substances aloe, manna, rhubarb, citron, camphor, gentian, myrrh, Saffron, boar root, senna leaves, angelica, Venetian theriac, fragrances and possibly enzymes and hormones.
  • GB-C-22 28 411 discloses the use of myrrh in conjunction with edible acids in ointments.
  • the object of the present invention is to provide a toning agent with very fast, residue-free absorption into the skin.
  • the above-mentioned object is achieved by a toning agent for topical application, in particular in the case of contusions, distortions, hematomas, periostitis, sciatica syndrome and lumbago, consisting of
  • the toning agent according to the invention is suitable for use in the care of the skin in the case of sports injuries such as bruises, strains, bruising or inflammation and irritation of the periosteum. In particular, it can also be used to revitalize and promote blood flow to the skin or limbs.
  • a particular area of application is intervertebral disc problems such as sciatica and lumbago as well as general skin care after sporting activities with a positive influence on the muscles.
  • the toning agent according to the invention can also be used as a massage oil.
  • the vegetable oils of the toning agent are selected from peanut oil, jojoba oil, avocado oil, almond oil, olive oil, walnut oil and hazelnut oil.
  • peanut oil is particularly preferred.
  • camphor or camphor oils are commercially available in a variety of forms.
  • camphor is preferably used in the form of camphor alcohol. According to the German Medicinal Products Book DAB 9, this is an aqueous solution of 1 part camphor, 9 parts ethanol (90%) and 2 parts water.
  • Myrrh is preferably used according to the invention in the form of myrrh tincture, containing 1 part of powdered myrrh and 5 parts of ethanol (90%), produced by maceration, according to DAB 9.
  • the task of the edible acids in the toning agent is to avoid fat residues of the agent and to improve the skin-friendliness.
  • Preferred edible acids of the present invention are selected from citric acid, tartaric acid, malic acid and acetic acid.
  • the acid can also be introduced in the form of fruit vinegar or fruit acid, for example.
  • Citric acid is preferably used directly in the form of lemon juice, which is obtained by squeezing lemons. In particular, the natural ingredients of the lemon, especially its vitamins, are incorporated into the toning agent.
  • composition of the individual components is less critical, it is advisable to follow the basic recipe for a balanced composition, in particular for very quick absorption in the skin without residues.
  • the toning agent is preferably composed of
  • camphor in the form of camphor alcohol
  • myrrh in the form of myrrh doors
  • 25 to 35 parts by weight of edible acid in the form of lemon juice 20 to 30 parts by weight of camphor in the form of camphor alcohol, 10 to 30 parts by weight of myrrh in the form of myrrh doors and 25 to 35 parts by weight of edible acid in the form of lemon juice.
  • the agents are to be shaken well and applied thinly as required.

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention concerns a liniment for topical application, in particular for contusions, sprains, haematomas, periostitis, ischial syndrome and lumbago. It contains: (a) plant oils; (b) camphor; (c) myrrh; (d) at least one fruit acid, or a mixture of such acids. The liniment is absorbed rapidly by the skin and leaves no residue.

Description

Tonisierendes Mittel  Toning agent
Die Erfindung betrifft ein tonisierendes Mittel zur topischen Anwendung auf rein pflanzlicher Basis. The invention relates to a toning agent for topical application on a purely vegetable basis.
Die Wirkung von Campher als Depot-Anaieptikuin. Desinfiziens und zur Lokalreizung ist- bekannt. Kyrrhenöle werden aus dem an der Luft getrockneten Saft mehrerer Arten der Gattung Commiphora gewonnen und dienen in der Parfümerie zur Erzielung orientalischer Noten in Parfumkompositionen. The effect of camphor as a depot anaieptic. Disinfectants and local irritation are known. Kyrrhen oils are obtained from the air-dried juice of several species of the Commiphora genus and are used in perfumery to achieve oriental notes in perfume compositions.
Aus der DE-A-21 50 297 sind medizinische Heilsalben bekannt, die aus natürlichen Fetten (tierischer oder pflanzlicher Herkunft) Alkohol, Bienenhonig, Hefe (aller Arten), den Wirkstoffen Aloe, Manna, Rhabarber, Zitwer, Kampfer, Enzian, Myrrhe, Safran, Eberwurz, Sennesblätter, Angelika, venezianischer Theriak, Riechstoffen und ggf. Enzymen und Hormonen bestehen. Aus GB-C-22 28 411 ist die Verwendung von Myrrhe in Verbindung mit Genußsäuren in Salben bekannt. From DE-A-21 50 297 medicinal healing ointments are known which, from natural fats (of animal or vegetable origin), alcohol, bee honey, yeast (all types), the active substances aloe, manna, rhubarb, citron, camphor, gentian, myrrh, Saffron, boar root, senna leaves, angelica, Venetian theriac, fragrances and possibly enzymes and hormones. GB-C-22 28 411 discloses the use of myrrh in conjunction with edible acids in ointments.
Die Aufgabe der vorliegenden Erfindung besteht in der Bereitstellung eines tonsierenden Mittels mit sehr schneller, rückstandsfreier Aufnahme in die Haut. Die vorstehend genannte Aufgabe wird gelöst durch ein tonisierendes Mittel zur topischen Anwendung insbesondere bei Kontusionen, Distorsionen, Hämatomen, Periostitis, Ischias-Syndro und Lumbago, bestehend aus The object of the present invention is to provide a toning agent with very fast, residue-free absorption into the skin. The above-mentioned object is achieved by a toning agent for topical application, in particular in the case of contusions, distortions, hematomas, periostitis, sciatica syndrome and lumbago, consisting of
(a) pflanzlichen Ölen,  (a) vegetable oils,
(b) Campher,  (b) camphor,
(c) Myrrhe und  (c) myrrh and
(d) wenigstens eine oder Gemische von Genußsäuren.  (d) at least one or mixtures of edible acids.
Das erfindungsgemäße tonisierende Mittel ist zur Anwendung zur Pflege der Haut bei Sportverletzungen wie Prellungen, Zerrungen, Blutergüssen oder Knochenhautentzündungen und -reizungen geeignet. Es kann insbesondere auch zur Belebung und Förderung der Durchblutung der Haut oder Gliedmaßen eingesetzt werden. Ein besonderes Anwendungsgebiet sind Bandscheibenprobleme wie Ischias und Hexenschuß sowie die allgemeine Hautpflege nach sportlicher Betätigung mit einem positiven Einfluß auf die Muskulatur. So kann das erfindungsgemäße tonisierende Mittel auch als Massageöl eingesetzt werden. The toning agent according to the invention is suitable for use in the care of the skin in the case of sports injuries such as bruises, strains, bruising or inflammation and irritation of the periosteum. In particular, it can also be used to revitalize and promote blood flow to the skin or limbs. A particular area of application is intervertebral disc problems such as sciatica and lumbago as well as general skin care after sporting activities with a positive influence on the muscles. Thus, the toning agent according to the invention can also be used as a massage oil.
In einer besonderen Ausführungsform der vorliegenden Erfindung sind die pflanzlichen Öle des tonisierenden Mittels ausgewählt aus Erdnußöl, Jojobaöl, Avocadoöl, Mandelöl, Olivenöl, Walnußδl und Haselnußöl. Besonders bevorzugt im Sinne der vorliegenden Erfindung ist Erdnußöl. In a particular embodiment of the present invention, the vegetable oils of the toning agent are selected from peanut oil, jojoba oil, avocado oil, almond oil, olive oil, walnut oil and hazelnut oil. For the purposes of the present invention, peanut oil is particularly preferred.
Campher bzw. Campheröle sind in vielfältiger Form im Handel. Bevorzugterweise wird im Sinne der vorliegenden Erfindung Campher in Form von Campherspiritus eingesetzt. Hierbei handelt es sich nach dem Deutschen Arzneimittelbuch DAB 9 um eine wäßrige Lösung aus 1 Teil Campher, 9 Teilen Ethanol (90 %) und 2 Teilen Wasser. Camphor or camphor oils are commercially available in a variety of forms. For the purposes of the present invention, camphor is preferably used in the form of camphor alcohol. According to the German Medicinal Products Book DAB 9, this is an aqueous solution of 1 part camphor, 9 parts ethanol (90%) and 2 parts water.
Myrrhe wird vorzugsweise erfindungsgemäß in Form von Myrrhentinktur, enthaltend nach DAB 9 1 Teil pulverisierte Myrrhe und 5 Teile Ethanol (90 %), hergestellt durch Mazeration, eingesetzt. Die Aufgabe der Genußsäuren in dem tonisierenden Mittel besteht darin, Fettrückstände des Mittels zu vermeiden und die Hautfreundlichkeit zu verbessern. Bevorzugte Genußsäuren der vorliegenden Erfindung sind ausgewählt aus Zitronensäure, Weinsäure, Äpfelsäure und Essigsäure. Die Säure kann beispielsweise auch in Form von Obstessig oder Obstsäure eingebracht werden. Bevorzugt wird Zitronensäure direkt in Form von Zitronensaft eingesetzt, der durch Auspressen von Zitronen erhalten wird. Hierbei werden insbesondere die natürlichen Bestandteile der Zitrone, vor allem deren Vitamine, mit in das tonisierende Mittel eingebracht. Myrrh is preferably used according to the invention in the form of myrrh tincture, containing 1 part of powdered myrrh and 5 parts of ethanol (90%), produced by maceration, according to DAB 9. The task of the edible acids in the toning agent is to avoid fat residues of the agent and to improve the skin-friendliness. Preferred edible acids of the present invention are selected from citric acid, tartaric acid, malic acid and acetic acid. The acid can also be introduced in the form of fruit vinegar or fruit acid, for example. Citric acid is preferably used directly in the form of lemon juice, which is obtained by squeezing lemons. In particular, the natural ingredients of the lemon, especially its vitamins, are incorporated into the toning agent.
Obwohl die genaue Zusammenstellung der einzelnen Bestandteile weniger kritisch ist, empfiehlt sich zur ausgewogenen Zusammensetzung, insbesondere zur sehr schnellen Aufnahme in der Haut ohne Rückstände, die Einhaltung der nachfolgenden Grundrezeptur. Although the exact composition of the individual components is less critical, it is advisable to follow the basic recipe for a balanced composition, in particular for very quick absorption in the skin without residues.
Demgemäß besteht das tonisierende Mittel vorzugsweise aus Accordingly, the toning agent is preferably composed of
20 bis 30 Gew.-Teilen pflanzlichen Ölen,  20 to 30 parts by weight of vegetable oils,
20 bis 30 Gew.-Teilen Campher in Form von Campherspiritus, 10 bis 30 Gew.-Teilen Myrrhe in Form von Myrrhetinktu'r und 25 bis 35 Gew.-Teilen Genußsäure in Form von Zitronensaft.  20 to 30 parts by weight of camphor in the form of camphor alcohol, 10 to 30 parts by weight of myrrh in the form of myrrh doors and 25 to 35 parts by weight of edible acid in the form of lemon juice.
Zur topischen Anwendung sind die Mittel gut zu schütteln und, je nach Bedarf, dünn aufzutragen. For topical application, the agents are to be shaken well and applied thinly as required.
Beispiel example
Ein tonisierendes Mittel, hergestellt aus A toning agent made from
275 ml Ernußöl,  275 ml nut oil,
275 ml Campherspiritus (DAB 9),  275 ml camphor alcohol (DAB 9),
150 ml Myrrhetinktur (DAB 9) und  150 ml myrrh tincture (DAB 9) and
300 ml Zitronensaft  300 ml lemon juice
wurde im Verlauf von 4 Wochen täglich nach allgemeiner sportlicher Betätigung zur Behandlung einer Oberschenkelzerrung, Knöchelverstauchung und Muskelschmerzen eingesetzt. Die eingetretene Wirkung zeigte sich in einem allgemeinen Wohlbefinden und Linderung des Schmerzzustandes. was used daily for 4 weeks after general physical activity to treat a thigh strain, ankle sprain and muscle pain. The effects that came about were shown in a general well-being and relief of the pain.

Claims

P a t e n t a n s p r ü c h e Patent claims
1. Tonisierendes Mittel zur topischen Anwendung insbesondere bei Kontusionen, Distorsionen, Hämatomen, Periostitis, IschiasSyndrom und Lumbago, bestehend aus 1. Toning agent for topical use, in particular in the case of contusions, distortions, hematomas, periostitis, sciatica syndrome and lumbago, consisting of
(a) pflanzlichen Ölen,  (a) vegetable oils,
(b) Campher,  (b) camphor,
(c) Myrrhe und  (c) myrrh and
(d) wenigstens eine oder Gemische von Genußsäuren.  (d) at least one or mixtures of edible acids.
2. Tonisierendes Mittel nach Anspruch 1, dadurch gekennzeichnet, daß die pflanzlichen Öle ausgewählt sind aus Erdnußöl, Jojobaöl, Avocadoöl, Mandelöl, Olivenöl, Walnußöl und Haselnußöl. 2. Toning agent according to claim 1, characterized in that the vegetable oils are selected from peanut oil, jojoba oil, avocado oil, almond oil, olive oil, walnut oil and hazelnut oil.
3. Tonisierendes Mittel nach Anspruch 1 oder 2, enthaltend Campher in Form von Campherspiritus. 3. Toning agent according to claim 1 or 2, containing camphor in the form of camphor alcohol.
4. Tonisierendes Mittel nach einem oder mehreren der Ansprüche 1 bis 3, enthalten Myrrhe in Form von Myrrhetinktur. 4. Toning agent according to one or more of claims 1 to 3, contain myrrh in the form of myrrh tincture.
5. Tonisierendes Mittel nach einem oder mehreren der Ansprüche 1 bis 4, dadurch gekennzeichnet, daß die Genußsäuren ausgewählt sind aus Zitronensäure, Weinsäure, Äpfelsäure und Essigsäure. 5. Toning agent according to one or more of claims 1 to 4, characterized in that the edible acids are selected from citric acid, tartaric acid, malic acid and acetic acid.
6. Tonisierendes Mittel nach Anspruch 5, enthaltend Zitronensäure in Form von Zitronensaft. 6. Toning agent according to claim 5, containing citric acid in the form of lemon juice.
7. Tonisierendes Mittel nach einem oder mehreren der Ansprüche 1 bis 6, bestehend aus 7. Toning agent according to one or more of claims 1 to 6, consisting of
20 bis 30 Gew.-Teile pflanzlichen Ölen,  20 to 30 parts by weight of vegetable oils,
20 bis 30 Gew.-Teile Campher in Form von Campherspiritus , 20 to 30 parts by weight of camphor in the form of camphor alcohol,
10 bis 30 Gew . -Teile Myrrhe in Form von Myrrhetinktur und10 to 30 wt. Parts of myrrh in the form of myrrh tincture and
25 bis 35 Gew.-Teile Genußsäure in Form von Zitronensaft. 25 to 35 parts by weight of edible acid in the form of lemon juice.
PCT/EP1992/001236 1991-06-04 1992-06-04 Liniment WO1992021358A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19914118240 DE4118240C2 (en) 1991-06-04 1991-06-04 Toning agent
DEP4118240.5 1991-06-04

Publications (1)

Publication Number Publication Date
WO1992021358A1 true WO1992021358A1 (en) 1992-12-10

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AU (1) AU1918792A (en)
DE (1) DE4118240C2 (en)
WO (1) WO1992021358A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP928A (en) * 1995-12-14 2001-01-15 Novelos Therapeutics Inc Cytokine and hemopoietic factor endogenous production enhancer and methods of use thereof.

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2150297A1 (en) * 1971-10-08 1973-04-12 Edeltraud Otto Cosmetic ointment - made entirely of naturally occuring materials
DE2353386A1 (en) * 1973-10-25 1975-05-07 Helmut Mueller Rheumatism and lumbago treatment compsn. - contg. formic acid, camphor, ammonia, turpentine, templin oil, anisol, ether, olive oil and soap
US4592912A (en) * 1983-10-31 1986-06-03 Harriet Nickolaus Ache and pain relieving and preventing composition
US4883664A (en) * 1987-06-29 1989-11-28 Mary Sharkey Medicinal salve
WO1991004010A1 (en) * 1989-09-12 1991-04-04 Ivy Jeffery W An external analgesic lotion and method of making

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8904139D0 (en) * 1989-02-23 1989-04-05 Joanides Margarita A cosmetic composition

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2150297A1 (en) * 1971-10-08 1973-04-12 Edeltraud Otto Cosmetic ointment - made entirely of naturally occuring materials
DE2353386A1 (en) * 1973-10-25 1975-05-07 Helmut Mueller Rheumatism and lumbago treatment compsn. - contg. formic acid, camphor, ammonia, turpentine, templin oil, anisol, ether, olive oil and soap
US4592912A (en) * 1983-10-31 1986-06-03 Harriet Nickolaus Ache and pain relieving and preventing composition
US4883664A (en) * 1987-06-29 1989-11-28 Mary Sharkey Medicinal salve
WO1991004010A1 (en) * 1989-09-12 1991-04-04 Ivy Jeffery W An external analgesic lotion and method of making

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP928A (en) * 1995-12-14 2001-01-15 Novelos Therapeutics Inc Cytokine and hemopoietic factor endogenous production enhancer and methods of use thereof.

Also Published As

Publication number Publication date
DE4118240C2 (en) 1997-08-14
DE4118240A1 (en) 1992-12-10
AU1918792A (en) 1993-01-08

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