WO1992017384A1

WO1992017384A1 - Package of drug, method of making said package, and method of and device for feeding said package

Info

Publication number: WO1992017384A1
Application number: PCT/JP1992/000403
Authority: WO
Inventors: Daishiro Fujishima; Shinichiro Fujishima; Junichi Manabe
Original assignee: Daishiro Fujishima; Shinichiro Fujishima; Junichi Manabe
Priority date: 1991-04-01
Filing date: 1992-04-01
Publication date: 1992-10-15
Also published as: JP3092193B2; JPH04311437A; AU1560492A

Abstract

A package of drug for wrapping up such drug as generating or absorbing gas with a packaging material, which intends to provide a package of drug prevented from losing gas absorbing and generating capabilities of the drug contained therein, and, further, to provide a method and a device for feeding said package. The packaging material (1) comprises bonded laminates of an air-permeable material a to form the internal surface of the package and non-air-permeable packaging film L to form the outer surface, and is in such a structure that yarn-like or band-like body (10) is interposed between said air-permeable packaging material a and non-air-permeable packaging film L. A package A of drug of this invention is used as a package having functions to absorb oxygen and moisture in the ambient atmosphere and to emit sterilizing gas or fragrance to the outside as required by the drug F contained therein.

Description

Specification

Pharmaceutical package, method of manufacturing the same, method of supplying pharmaceutical package, and device for supplying the same

Technical field

The present invention relates to a medicine package that absorbs or generates gas, a method of manufacturing the same, a method of supplying a medicine package, and a supply device thereof.

Background art

Conventionally, it absorbs or absorbs gases such as oxygen absorbers such as iron powder and hydrosulfite, hygroscopic agents such as silica gel and quick lime (CaO), and ethanol generators in which ethanol is adsorbed to the filler. It is known that the generated medicine is packaged in a breathable packaging material. If any of these air-permeable packaging materials are left in the air as they are, the chemicals inside will react with oxygen or moisture in the air, or the gas generating agent enclosed in the air It has the characteristic that it dissipates in the water and gradually loses its effectiveness.

As described above, since such a drug package performs a gas absorption reaction and a gas generating action as it is, there is a remarkable difficulty in its storage and supply operation to a packaging container. In other words, it is necessary to store this package in a completely airtight sealed container, and to supply it to the package quickly. In particular, in the case of a conventional package, a large number of the packages are loaded in advance in an automatic supply device, and when the supply device attempts to sequentially and sequentially fill the packaging containers containing the articles, the package is required. Gas absorption capacity and gas generation capacity depend on the first and last In this case, a considerable difference occurs, and the package at the end has a significant loss of its gas absorbing ability and gas generating ability.

Disclosure of the invention

SUMMARY OF THE INVENTION The present invention solves the above-described problems encountered in conventional drug packages, and prevents the loss of gas absorption capacity and gas generation capacity of a drug enclosed therein, a method of manufacturing the same, and supply of the drug package. It is an object to provide a method and a supply device thereof.

The present inventors have conducted intensive studies to solve the above problems, and as a result, have completed the present invention.

That is, according to the present invention, there is provided a package in which an agent for generating or absorbing gas is wrapped with a packaging material, wherein the packaging material is a gas-permeable packaging material forming an inner surface and a non-breathable film forming an outer surface. A thread or a band is interposed between the breathable packaging material and the non-breathable film, and the thread or the belt is pulled above the outer surface of the non-breathable film. Accordingly, there is provided a medicine package A (1) in which the contact portion of the non-breathable film with the thread or the band is broken.

Further, according to the present invention, there is provided a package in which a gas generating or absorbing agent is wrapped with a packaging material, wherein the packaging material is a gas-permeable packaging material forming an inner surface and a non-breathable film forming an outer surface. A thread or a band is adhered to the outer surface of the air-impermeable film, and the thread or the band is pulled above the outer surface of the air-impermeable film to form the air-impermeable film. The present invention provides a pharmaceutical package A (2) which is capable of breaking a bonding portion of the conductive film with the thread or band. Furthermore, according to the present invention, there is provided a package in which a gas-generating or absorbing agent is wrapped with a packaging material, wherein the packaging material comprises a gas-permeable packaging material forming an inner surface and a gas-impermeable packaging material forming an outer surface. A fibrous body or a band attached to the outer surface or the inner surface of the non-breathable film, wherein the fibrous body or the band is adhered to the outer surface of the non-breathable film; A drug package A (3) is provided which is pulled upward to break the adhesive portion of the non-breathable film with the thread or band.

Furthermore, according to the present invention, when supplying a drug package for generating or absorbing gas to a predetermined location, the above-mentioned drug packages A (1) to A (3) are used as the drug package. A method for supplying a medicine package, comprising: pulling a thread or a band attached to a package above the outer surface of the air-impermeable film, breaking the air-impermeable film, and supplying the fractured film to a predetermined location. Is provided.

Still further, according to the present invention, a long strip-shaped body in which a large number of the pouch-shaped packaging bodies A (1) to A (3) for accommodating a medicine therein are sequentially connected to each pouch-shaped packaging body. An apparatus for cutting and supplying the drug package to a predetermined location, wherein the drug package is sequentially cut into small pouches and supplied to a predetermined location, and a thread or band attached to the drug package. A supply device for a medicine package, characterized in that the supply device has a mechanism for pulling a thread or a band, which pulls the filament upward from the outer surface of the air-impermeable film.

Furthermore, according to the present invention, there is provided a package in which a drug that absorbs or generates gas is packaged with a packaging material, wherein the packaging material is an air-permeable package forming an inner layer. Has a structure in which a non-breathable film forming an outer layer is bonded to the breathable surface of the packaging material, and the non-breathable film is peelably weakly bonded to the breathable surface of the breathable packaging material. A medicine package B that absorbs or generates gas is provided.

Furthermore, according to the present invention, when supplying a medicine package for absorbing or absorbing gas to a predetermined location, the medicine package B is used as the medicine package, and the non-permeable property of the package B is used. A method for supplying a medicine package, characterized in that the film is supplied to a predetermined location after the film is peeled off.

Furthermore, according to the present invention, a long band-shaped body in which a large number of the small bag-shaped packages B containing a medicine are accommodated therein is sequentially cut into each small bag-shaped package and supplied to a predetermined location. An automatic cutting / supplying mechanism for sequentially cutting the medicine package into small pouches and supplying the medicine package to predetermined locations, and a mechanism for taking off a non-breathable film for peeling off the non-breathable film of the medicine package. A supply device for a medicine package characterized by having the above is provided.

Further, according to the present invention, there is provided a method of manufacturing a medicine package B which absorbs or generates gas,

(i) supplying a breathable packaging material having a breathable surface portion and a non-breathable adhesive film between the crimping holes;

(ii) pressing a non-breathable adhesive film on the permeable surface of the packaging material between the compression rolls to cover the permeable surface of the packaging material with the non-breathable adhesive film;

(iii) using a packaging material whose air-permeable surface is covered with a non-air-permeable adhesive film as at least a part of a bag-making material, to form a bag having an opening; Process,

(iv) filling a drug that absorbs or generates gas through the opening of the bag;

(V) a step of sealing the opening of the bag filled with the drug

The present invention provides a method for producing a medicine package which absorbs or generates a gas comprising: The agents in the present invention are gas-absorbing or gas-producing. Gas-absorbing substances are substances that have the ability to adsorb or absorb oxygen, moisture, odor, carbon dioxide, or harmful gases (eg, hydrogen sulfide, sulfur dioxide, etc.) that are undesirable for storage. Ari, various conventionally known substances are included. For example, these include various oxygen absorbers such as iron powder and hydrosulfite for deoxygenation, silica gel, zeolite, activated clay, phosphorus pentoxide, and calcium oxide for dehumidification or drying. , Potassium oxide, aluminum oxide, anhydrous calcium sulfate, magnesium oxide, magnesium hydroxide, sodium hydroxide, calcium chloride, etc. For deodorization, activated carbon, zeolite, activated clay, bentonite, diatomaceous earth , Ion-exchange resins, etc., and also alkaline substances such as sodium hydroxide, calcium hydroxide, magnesium hydroxide, calcium oxide, etc. to adsorb acid gases such as hydrogen sulfide, sulfur dioxide, and gas carbonate. Hydroxides and oxides of metals such as magnesium oxide, ethylene gas absorption For, there is such Zeorai door. Gas-producing substances are substances that generate gases that are preferable for preservation of goods, and substances that have a bactericidal / bacteriostatic effect, for example, ethanol, substances containing chlorine dioxide (stabilized chlorine dioxide, chlorite, etc.). Salt solution, etc.), chlorine-containing substances (hypochlorite and its solution, chlorinated water, etc.) And sorbic acid in ethanol, isothiocyanate or a solution thereof, and hinokitiol or a solution thereof.

In the present invention, when the gas-absorbing or gas-generating agent is a liquid, the liquid may be impregnated with a porous substance, encapsulated using a resin, or the like, and may be a solid state that is easy to handle. And wrapped in packaging material. Examples of the porous substance include activated carbon, silica, alumina, zeolite, and diatomaceous earth. If the gas-absorbing or gas-generating agent is a solid, it should be packaged as it is or mixed with a filler. Examples of the breathable packaging material used in the present invention include paper, nonwoven fabric, perforated plastic film, laminated adhesive of perforated plastic film and paper / nonwoven fabric, and a film having only a part of its surface formed on a gas permeable surface. Any of the well-known ones can be used. In addition, it is preferable that a heat-sealing resin layer is formed on the back surface of this packaging material to be used as a heat-sealing packaging material.

As the non-breathable film, various plastic films are used in addition to metal films such as aluminum foil and copper foil. The non-breathable film is provided with a pressure-sensitive adhesive layer on its back surface in advance, and is used as an adhesive film.

BRIEF DESCRIPTION OF THE FIGURES

FIG. 1 is an explanatory sectional view of a medicine package A of the present invention.

FIG. 2 is a perspective view of the medicine package A of the present invention.

FIG. 3 shows an explanatory sectional view of one embodiment of the packaging material.

FIG. 4 shows an explanatory sectional view of another embodiment of the packaging material. FIG. 5 is an explanatory sectional view of another embodiment of the medicine package A of the present invention.

FIG. 6 is an explanatory sectional view of still another embodiment of the medicine package A of the present invention.

FIG. 7 shows an explanatory sectional view of still another embodiment of the medicine package A of the present invention.

FIG. 8 shows a front view of a long package in which small bag-like packages P are continuously connected in a belt shape.

FIG. 9 shows a sectional view of the package P in FIG.

FIG. 10 is an explanatory view of an apparatus system for cutting and supplying a long package in which a small bag-shaped package P is continuously connected in a strip shape to a small bag package.

FIG. 11 (a) is an explanatory cross-sectional view of a drug package of the present invention in which a gas permeable surface part a ′ of a gas permeable packaging material a is covered with a non-air permeable film L to form a packaging material 1. FIG. 12 to FIG. 14 show modifications thereof.

BEST MODE FOR CARRYING OUT THE INVENTION

Next, an embodiment of the medicine package of the present invention will be described with reference to the drawings.

FIG. 1 shows a packaging material 1 formed by laminating and bonding a non-breathable film L via a filament 10 on a breathable packaging material a formed entirely as a breathable surface a ′. FIG. 3 is an explanatory cross-sectional view of a package body enclosing a drug F by using the method shown in FIG. In FIG. 1, reference numeral 2 denotes a seal portion.

FIG. 2 is a perspective view of the medicine package, and FIG. 3 is an explanatory sectional view of the packaging material 1.

2 and 3, reference numeral 10 denotes a filament. Also, in Figure 3, · A indicates a breathable material, L indicates a non-breathable film, and C indicates an adhesive layer.

In this package, when the filament 10 is pulled upward, the non-breathable film L is broken at the filament portion due to the tension of the filament 10, and the non-breathable film L is broken by the fracture. The broken part becomes a part having air permeability, and the inside of the package communicates with the outside atmosphere of the package. As a result, the medicine F inside the package becomes free from the external atmosphere. It can react with chemical components (eg, oxygen, moisture, carbon dioxide, odor, etc.) and can diffuse chemical components (eg, germicidal gas, odor, etc.) into its external atmosphere. become.

In order to facilitate the breaking of the air-impermeable film L, the air-impermeable film L is made of a material that is easily torn in the same direction as the length of the filament, for example, a thin film stretched in the same direction as the filament. Preferably, it is a plastic film. In addition, the filament 10 is made of a material having poor adhesiveness, such as polypropylene, Teflon, or nylon, so that the breathable packaging material a does not break and the peeling from the adhesive layer C is facilitated. It is preferably formed of such a material as described above, and it is also preferable that the surface thereof is previously coated with a release agent. Further, it is also preferable to adjust the adhesive force of the adhesive layer C relatively weakly.

FIG. 4 is an explanatory cross-sectional view of a modified example of the packaging material 1 of the medicine package, in which the band 10 is adhered to a part of the outer surface of the air-impermeable film L. In this medicine package, when the belt 10 is pulled upward, the non-breathable film L is broken and peeled at the bonding portion with the belt due to the tension. In this packaging material 1, the gap between the band 10 and the impermeable film L The adhesive strength is set to be larger than the adhesive strength between the non-breathable film L and the breathable packaging material a, and is set so as to cause the material breakage of the non-breathable film. The non-breathable film L is preferably a thin plastic film that is easy to tear in the same direction as the length direction of the strip 10. FIGS. 5 and 6 illustrate another embodiment of the drug package. It is a cross-sectional view. In this package, the gas-permeable packaging material a and the air-impermeable film L are adhered only at the peripheral portion thereof, not at the intermediate portion thereof, and a gap S exists between the two. In the case of FIG. 5, the band 10 is adhered to the inner surface of the non-permeable film L, and in the case of FIG. 6, the band 10 is adhered to the outer surface of the non-permeable film. .

FIG. 7 shows still another embodiment of the medicine package, wherein the gas-permeable packaging material a is formed as a gas-permeable surface a ′ with only a part of its surface, and has a non-gas-permeable body 10 having a band 10 thereon. It has a structure in which the conductive film L is laminated and bonded. In this case, the air permeable packaging material a can be formed, for example, by forming a large number of pores on a predetermined surface of a non-air permeable film such as a plastic film or an aluminum foil film.

Fig. 8 and Fig. 9 show the use of an automatic feeder to form small bag-shaped packages P that are used to continuously fill drug packages P into bags or containers containing food, etc. The explanatory view of the long strip-shaped package 14 thus obtained is shown. In these figures, as shown in FIG. 4, the packaging material 1 is formed of a non-breathable film L having an outer surface having a band 10 and an inner surface thereof is formed of a breathable packaging material a, as shown in FIG. 3 shows the sealing surface of packaging material 1. When the package P is supplied (distributed) using an automatic distribution machine, the package P is adhered to the surface of the air-impermeable film L. The strip 10 is continuously peeled off from its surface together with a part of the air-impermeable film, and then cut sequentially at the sealing surface 3 and each cut package P is sequentially cut into bags or containers. throw into.

FIG. 10 is an explanatory view of an apparatus system for cutting each small bag-shaped package P from a long strip-shaped package 14 using an automatic feeding machine and supplying the cut package P to a predetermined location.

The long band-shaped package 14 is supplied to the automatic feeder 15, but prior to the supply, the band 10 bonded to the surface of the packaging material 1 of the package 14 is rotated by the rotating roll 1. The surface of the package 14 is peeled off by the tension between the package 8 and the package 14. In the stripping of the strip 10, as described above, the portion of the non-breathable film L forming the surface of the packaging material 1 that adheres to the strip 10 is also simultaneously peeled off, and rotated together with the strip 10. It is wound on roll 18. The tension for peeling the strip 14 can be formed by using the torque of the rotating roll installed in the automatic feeder 15 (that is, the force pulling the package 14 downward). 18 can be rotated with a constant force and formed by utilizing the torque at that time. When the belt 10 is peeled off using the torque of the rotating roll installed in the automatic feeder 15, the torque of the rotating roll 18 does not need to be large, and Any size may be used as long as it is necessary to wind the strip 10 wound. As the automatic feeder 15, any package can be used as long as it can take the package 14 into the device and cut it at the sealing surface 3 of the package 14. For example, an automatic distribution machine (KD_700, KD900) manufactured by Mitsuhashi Manufacturing Co., Ltd. can be used.

The pouch-shaped package P obtained by cutting with the automatic feeder 15 is It is supplied to a predetermined place by 16.

In the medicine package A of the present invention, since the outer surface of the packaging material for packing the medicine is formed of a non-breathable film, the inside and outside of the package are substantially shut off. Therefore, the outside air does not enter into the package, and the inside of the medicine vapor does not escape to the outside. Loss is prevented.

When the package A of the present invention is used, the filament or band attached to the package A is pulled over the surface of the package, and the non-breathable film forming the outer surface of the packaging material is broken. Communication between the inside and the outside of the body can be established, whereby gas absorption and gas generation by the encapsulated drug are started.

The package A of the present invention is widely used in various fields, particularly in the food field, by utilizing the action of a drug enclosed therein, but the package A of the present invention has an outer surface as described above. As long as the formed non-breathable film is not broken by the thread or band, it can stably hold the drug encapsulated inside, so it is extremely excellent in handling, storage and supply. It is. By using a combination of a long strip to which the pouch-shaped package of the present invention is connected and an automatic feeder, the pouch-shaped package is continuously formed, and this is placed at a predetermined location, for example, food. And so on. When such an automatic feeding machine is used, even if the automatic feeding machine is stopped halfway, the long strip-shaped package does not break the non-breathable film on its surface through the thread or the strip. Automatic feeding machine because consumption of chemicals does not occur Has the advantage that it can be stopped arbitrarily and for a long time as needed. When using a conventional package whose surface is formed of a breathable packaging material, if the automatic feeder is stopped for a long time, a large amount of the drug will be consumed. However, in the case of the present invention, there is no such disadvantage.

Next, an embodiment of the package B of the present invention will be described with reference to the drawings.

Fig. 11 (a) shows a packaging material formed by laminating and adhering a non-breathable film L on the entire surface of a gas-permeable packaging material a formed entirely as a gas-permeable surface. FIG. 2 shows a cross-sectional explanatory view of a package in which a medicine F is packaged. In FIG. 11A, reference numeral 2 denotes a seal portion. FIG. 11 (b) shows an explanatory sectional view of the packaging material 1.

In the present invention, the adhesive between the breathable packaging material a and the non-breathable film L is releasably adhered, and if necessary, the non-breathable film L is peeled off from the surface of the breathable packaging material a. Can be. For this purpose, an adhesive between the packaging material a and the air-impermeable film L having a low adhesive strength or a removable adhesive (for example, “AS— In addition, a release agent can be applied in advance to the surface of the air-permeable packaging material a to facilitate the peeling. By providing a pressure-sensitive adhesive layer on the back surface of L in advance, the air-permeable packaging material a and the non-air-permeable film L can be easily bonded.

FIG. 12 (a) is an explanatory cross-sectional view of a medicine package formed using the breathable packaging material 1 shown in FIG. 12 (b). Packaging material used for this medicine package 1 is, as shown in FIG. 12 (b), the air-permeable packaging material a having an air-permeable surface part a ′ substantially along the center vertical direction to the right of the longitudinal center line. This is formed by pressing non-breathable film L against a ′. This packaging material 1 is folded around its center line to form a bag, and the bag is filled with a drug and sealed to obtain a drug package having the structure shown in FIG. 4 (a). be able to.

Fig. 13 shows a breathable packaging material a with a breathable surface a 'in the center, formed using two pieces of packaging material formed by pressing a non-breathable film on the breathable surface a'. The explanatory sectional view of the completed medicine package is shown.

Fig. 14 shows the use of a non-breathable packaging material b and a packaging material formed by pressing a non-breathable film over the entire surface of a breathable packaging material a formed entirely on the breathable surface part a '. The explanatory sectional view of the formed medicine package is shown.

Fig. 15 shows the use of an automatic filling machine to form a strip-shaped package in which each package P used to continuously fill a drug package P into a bag or container containing food is connected in a strip. FIG. In FIG. 15, as shown in FIG. 12 (b), the packaging material 1 is formed of a gas-permeable packaging material a to which a non-breathable film L is pressed. 3 indicates the sealing surface of the packaging material 1. When the package P is filled using an automatic filling machine, the air-impermeable film L is continuously peeled off from the surface, and is sequentially cut at the sealing surface 3, and each cut package P is cut. In a bag or container. As a device for cutting each small bag-shaped package P from a long band-shaped package using an automatic feeder and supplying it to a predetermined location, the device system shown in relation to the aforementioned package A is used. be able to. Next, a method for producing the medicine package B of the present invention will be described with reference to the drawings.

In FIG. 16, 21 is a winding roll of the non-breathable adhesive film L, 22 is a winding roll of the breathable wrapping material a, 23, 24 are pressure rolls, and 25 is an inner roll. Show.

In order to carry out the method of the present invention, first, the air-impermeable film L from the roll 21 and the air-permeable packaging material a from the roll 22 are re-pressed by the guide roll 25 to the pressure-bonded rolls 23 and 2. And a non-breathable adhesive film is pressed onto the breathable surface of the breathable packaging material a. In this compression bonding step, the air-permeable packaging material a is converted into a non-air-permeable material as a whole because the air-permeable surface of the air-permeable packaging material is laminated with the air-impermeable film. From between the pressure bonding rolls 23 and 24, the packaging material 1 whose entire surface is formed to be air-impermeable is taken up and wound on a roll. FIG. 17 is a perspective view of one embodiment of the roll-wrapped packaging material 1.

In the present invention, the packaging material 1 obtained as described above, which is entirely impermeable, is used as at least a part of the bag-making material, and is formed into a bag having an opening. After filling the medicine that absorbs or generates the gas through the opening as described above, the opening of the bag body is sealed to obtain a medicine package B.

The step of forming the above-described packaging material into a bag having an opening, the step of filling the bag with a drug, and the step of sealing the opening of the bag filled with the drug are all well-known steps. These series of steps can be continuously performed using a conventional automatic filling machine.

Claims

The scope of the claims

(1) A package in which a gas-generating or absorbing agent is wrapped in a packaging material, wherein the packaging material is a laminated adhesive between a gas-permeable packaging material forming an inner surface and a non-breathable film forming an external surface. A thread or a band is interposed between the air-permeable packaging material and the air-impermeable film, and the thread or the band is pulled above the outer surface of the air-impermeable film to thereby form the air-impermeable material. A pharmaceutical package which breaks a contact portion of a conductive film with a thread or a band.

(2) A packaging material containing a gas-generating or absorbing agent as a packaging material, wherein the packaging material is a laminate of a gas-permeable packaging material forming an inner surface and a non-breathable film forming an external surface. A thread or a band is adhered to the outer surface of the non-breathable material, and the thread or the band is pulled above the outer surface of the non-breathable film. A drug package which breaks a bonding portion between the thread and the band in the drug package.

(3) A package in which a gas-generating or absorbing agent is wrapped with a packaging material, the packaging material comprising a gas-permeable packaging material forming an inner surface and a non-breathable film forming an outer surface. A thread or a band is adhered to the outer or inner surface of the air-impermeable film, and the thread or the band is pulled above the outer surface of the air-impermeable film. A drug package which breaks an adhesive portion of the non-breathable film with the thread or band.

(4) The air-permeable packaging material is a perforated plastic film. 92/17384 ^ib Drug package of any of 1-3.

(5) The pharmaceutical package according to any one of claims 1 to 4, wherein the breathable packaging material is paper or nonwoven fabric.

(6) The pharmaceutical package according to any one of claims 1 to 4, wherein the breathable packaging material is a paper or a nonwoven fabric having a perforated plastic film adhered to the back surface.

(7) The pharmaceutical package according to claim 5 or 6, wherein the paper or nonwoven fabric is subjected to a water-repellent and / or oil-repellent treatment.

(8) The drug package according to any one of claims 1 to 7, wherein the non-breathable film is a plastic film or an aluminum foil.

(9) The pharmaceutical package according to any one of claims 1 to 8, wherein the thread or the band is made of plastic or metal. ·

(10) The drug package according to any one of claims 1 to 9, wherein the package is a long strip having a structure in which a large number of small bag-shaped packages accommodating a drug are connected.

(11) When supplying a drug package that generates or absorbs gas to a predetermined location, any one of the claims 1 to 10 is used as the drug package and attached to the package. A method for supplying a medicine package, comprising: pulling a thread-like body or a band-like body above the outer surface of the non-breathable packaging material 3 to break the non-breathable film and then supplying the broken piece to a predetermined location.

(1 2) An apparatus for sequentially cutting the medicine package of claim 10 into small bags and supplying the bag to a predetermined location, wherein the medicine package is automatically cut into small bags and supplied to a predetermined location. A cutting and feeding mechanism; and a filament which pulls a filament or a band attached to the medicine package upward from an outer surface of the air-impermeable film. Alternatively, a supply device for a medicine package, which has a belt take-off mechanism. .

(13) A package in which a drug that absorbs or generates gas is packaged with a packaging material, wherein the packaging material is formed by laminating a non-breathable film forming an outer layer on a breathable surface of a breathable packaging material forming an inner layer. A gas-absorbing or generating medicine package, characterized in that the gas-impermeable film has a closed structure, and the non-permeable film is peelably weakly adhered to a gas-permeable surface of a gas-permeable packaging material.

(14) The drug package according to claim 13, wherein the package is a long strip having a structure in which a large number of small bag-shaped packages each containing a drug are continuously connected.

(15) When supplying a medicine package for generating or absorbing gas to a predetermined location, the medicine package described in claim 14 is used, and the non-breathable material adhered to the package is used. A method for supplying a medicine package, comprising supplying a predetermined location after peeling off a film.

(16) An apparatus for sequentially cutting the medicine package of claim 14 into small pouches and supplying the medicine package to each small bag, and automatically cutting the medicine package into each small bag and supplying the medicine package to a predetermined place. An apparatus for supplying a medicine package, comprising: a cutting supply mechanism; and a mechanism for taking off a non-breathable film that peels off the non-breathable film on the surface of the medicine package.

(17) In a method of manufacturing a medicine package that absorbs or generates gas,

(i) a step of supplying a gas-permeable packaging material having a gas-permeable surface portion and a non-gas-permeable adhesive film between the pressure rolls;

(ii) between the pressure rolls, the air-permeable surface of the packaging material a Compressing a gas-permeable adhesive film to cover the gas-permeable surface of the packaging material with the air-impermeable pressure-sensitive adhesive film;

(iii) a step of forming a bag having an opening by using a packaging material in which the air-permeable surface is covered with a non-air-permeable adhesive film as a bag-making material;

(iv) a step of filling a gas absorbing or generating agent through the opening of the bag;

(V) a step of sealing the opening of the bag filled with the drug

A method for producing a pharmaceutical package which absorbs or generates a gas comprising: