WO1992006375A1

WO1992006375A1 - Device for preparing suspension of excrement, and instrument and rod for picking excrement

Info

Publication number: WO1992006375A1
Application number: PCT/JP1991/001270
Authority: WO
Inventors: Kenjiro Mori; Takashi Tsuji; Makiko Setoh; Yuichi Inoue; Kaneo Miyamoto
Original assignee: Nitto Denko Corporation; Fujisawa Pharmaceutical Co., Ltd.
Priority date: 1990-09-29
Filing date: 1991-09-24
Publication date: 1992-04-16
Also published as: AU8632291A

Abstract

A device for preparing suspension of excrement provided with: an excrement containing vessel comprising a vessel proper to contain fluid for making excrement suspension, a first lid body disposed at an opening part of said vessel proper and internally having means for filtering excrement suspension, and a second lid body capable of tightly sealing the opening in the upper part of said first lid body; and an excrement picking rod, as an independent body, which can be contained in said containing vessel and having a plurality of grooves formed on the side thereof for picking and storing excrement. An instrument for picking excrement provided with an excrement picking rod having grooves formed in the side of the tip thereof for picking and storing excrement and an excrement wiper slidably fitted over the rod, and with the excrement picking vessel having a lid. By the use of an instrument for preparing excrement suspension, excrement picking instrument and rod of this invention, operations to pick excrement, prepare a specimen, and inspect the specimen are made easy and sanitary without the possibility of soiling inspector's hands with excrement or suspension thereof.

Description

Specification

Stool suspension preparation device, stool collection device and stool collection rod

"Technical field"

The present invention relates to tools used for collecting feces and preparing fecal suspensions in clinical tests, particularly for testing occult blood and viruses in feces, and is mainly used in the field of medicine. Things.

`` Background technology J

Feces, like urine, are suitable as non-invasive test samples and are commonly used as samples in some tests. Recently, fecal occult blood tests using immunological methods such as latex agglutination, EIA, and RIA have attracted attention as primary screening tests for gastrointestinal cancers such as colorectal cancer.

In this test, it is necessary to collect a predetermined amount of feces and then suspend the feces in a liquid such as saline. Conventionally, this work has been performed by the inspector, but unnecessarily bothering the inspector and causing problems in hygiene. For this reason, in recent years, the subject himself / herself can perform the process from quantitative collection of feces to preparation of the suspension in a relatively hygienic and simple manner, and a feces collection container or feces suspension preparation tool. Has been proposed (Japanese Utility Model Laid-Open No. 62-69160).

This stool collection container is composed of a container body capable of storing a liquid for suspending feces, and a lid. A single stool collection rod inserted into the container body is fixed to the lid, and at least one cutout, recess, or through hole is provided at the tip of the stool collection rod as a stool storage unit. Have been. When collecting feces, is it the container itself? After removing the lid, piercing the tip of the stool collection rod fixed to the lid into the stool, and then wiping off excess stool, a predetermined amount of stool is held in the stool container. Thereafter, the fecal suspension can be prepared by sealing the container body with a lid. That is, since the stool storage unit is immersed in the liquid in the container body, the stool held in the stool storage unit is easily suspended in the liquid in the container body by shaking the container body. . The suspension thus obtained is taken out of the container via a filter by making a hole in the tip of the lid or cutting off the tip, and is subjected to the inspection.

On the other hand, the stool collection container described in Japanese Utility Model Laid-Open Publication No. 185568/88 is used for the same purpose as the above-mentioned container, but a groove is formed on the bottom of the tip of the stool collection rod. This has the effect that when the sampling rod is pierced into feces, the feces can be collected reliably and without variation.

However, in the above-mentioned stool collection containers, when stool excessively attached to the tip of the stool collection rod is wiped off with toy paper or the like, a part of the stool stored in the groove when wiped off tightly. May be dug out, resulting in inaccurate inspection. In addition, the stool collection rod fixed to the lid may come off from the lid or be damaged when wiping it tightly.

Furthermore, it is difficult to collect a certain amount of stool at a time using a stool collection rod provided with a stool collection and storage groove on the side of the tip. The collection rod was wiped with a piece of paper to remove excess feces adhering to parts other than the grooves. O

However, this operation is not only troublesome for the inspector, but also poses a problem from the viewpoint of hygiene such as dirty hands during wiping.

In any case, conventional stool suspension preparation tools, stool collection tools, and stool collection rods are complicated in stool collection and examination operations, and the examiner's hands are stained with stool and its suspension. There is a problem in one or more of the following points:

A first object of the present invention is to provide a sanitary stool suspension preparation tool which is easy to perform stool collection and inspection, does not cause the examiner's hands to be stained with stool or its suspension, and It is.

A second object of the present invention is to provide a stool collection rod and a stool collection tool that can easily collect and store a fixed amount of stool and are also preferable in terms of hygiene.

"Disclosure of the invention"

As a result of repeated studies to achieve the above object, the present inventors have found that a stool storage container or a stool suspension preparation tool having a specific structure is adopted, and that a stool collection rod is fixed to the lid. It has been found that the above-mentioned first object can be achieved by being separated from each other.

Further, a stool wiping tool is slidably fitted to a stool collection rod provided with a stool collection / storage groove on the side surface of the distal end portion. It has been found that the second purpose can be achieved by using the stool collection container together. The present invention has been completed based on the above-described new findings.First, the feces suspension preparation device of the present invention uses a liquid for feces suspension. A container body to be accommodated, a first lid provided at an opening of the container body, and a means for filtering a stool suspension therein; and a first lid provided at an upper portion of the first lid. Feces storage container comprising a second lid body capable of sealing the opening, and a feather feces as a separate body capable of being stored in the feces storage container and having a plurality of grooves on the side for collecting and storing feces. It has a sampling rod.

Second, the stool collection rod of the present invention is a stool collection rod provided with a groove for collecting and storing stool on the side surface of the tip, and the stool wiping tool is slidably fitted. It is a feature. Furthermore, the above-mentioned stool collection rod can provide a more suitable stool collection tool by using a stool collection container having a lid in combination.

Furthermore, by combining the feces suspension preparation device of the first invention with the feces collection rod or the feces collection device of the second invention, a more convenient feces collection device can be provided.

"Brief description of the drawings"

Fig. 1 is a cross-sectional view showing an example of a stool storage container constituting a stool suspension preparation device of the present invention, and Fig. 2 is a stool collection rod constituting a stool suspension preparation device of the present invention. FIG. 2 shows a perspective view showing one example. FIG. 3 is a perspective view of the stool collection rod of the present invention. FIG. 4 is a side view showing a state in which the lid of the stool collection container constituting the stool collection tool of the present invention is opened. FIG. 5 is a perspective view showing an example of a fecal wipe.

A · · · Feces storage container

1 · ■ · Container body

2. 1st lid

3-· '' Second lid 4 Filter

5 Liquid for fecal suspension

6 Stool collection rod

7 groove

8 Fecal wipe

9 Stool collection container

1 0 Container body

1 1

1 2 Hinge

1 3 Tab

1 4 Break

"Detailed description of the invention j

The stool collection tool of the present invention will be described more specifically with reference to the drawings. FIG. 1 is a cross-sectional view showing an example of a stool storage container constituting a stool suspension preparation tool of the present invention. The feces storage container A has a container body 1, a first lid 2, and a second lid 3.

The first lid 2 is screwed into the upper opening of the container body 1 and mounted in a liquid-tight manner. As the means for attaching the first lid 2, any means such as the above-mentioned screwing, crowning, fitting, and fixing can be arbitrarily adopted. Inside the first cover body 2 filters 4 such as a sponge or filter paper is provided as a means for filtering the stool suspension, a nozzle-shaped or openings in the ^upper: are provided. The second lid 3 is screwed into a nozzle-shaped opening provided on the top of the first lid 2 and is mounted in a liquid-tight manner. Using the same means as the mounting means it can.

The container body 1 contains a liquid 5 for feces suspension such as physiological saline or various buffers.

As the material of the container body 1, for the container body 1, a soft plastic material such as polyethylene or polypropylene is preferable. For the first lid 2 and the second lid 3, a relatively hard plastic material is preferably used.

FIG. 2 is a perspective view showing an example of a stool collection rod constituting the stool suspension preparation tool of the present invention.

The stool collection rod 6 is provided with a plurality of grooves 7 at the tip end for holding the stool after collecting the stool, and is preferably an elongated spatula-shaped so that the stool can be stored in the container from the opening of the container body 1. . The grooves can be provided in any shape. The width and depth of the groove are not particularly limited, but the width is 0.1 to 1.0 mm and the width of the groove is deep so that when storing excess feces, the stool stored in the groove cannot be wiped off. It is preferable that the thickness is in the range of 0.5 to 1.0, and the bottom of the groove is preferably formed in a round shape so as to easily dissolve feces.

By the way, in the case of a fecal test, unlike in the case of a blood test or urine test, the test substance is not always uniformly distributed in the feces. It may be preferable to collect them. In response to such a request, if there is only one stool collection stick, it is necessary to pierce several places, but one stab fills the stool collection section, and then separates the stool collection rod into feces. There is a problem that stool cannot be collected even if it pierces the area. Therefore, in the stool suspension preparation device of the present invention,

In order to reliably and quantitatively collect the required amount of feces from several places, it is preferable to use at least two of them, and the same applies to the feces collection rod shown in Fig. 3 below.

As the material of the fecal collection rod 6, for example, a hard plastic such as polystyrene or ABS resin, a metal, glass, or wood is used.

The fecal collection rod 6 is a separate body, but the separate body means a state in which it is not fixed to the feces storage container A. However, it may be detachably attached to the feces storage container A by an appropriate means.

The stool suspension preparation tool, stool collection tool, and stool collection rod of the present invention are specifically used as follows.

A predetermined amount of the liquid for feces suspension 5 is put into the container body 1 of the feces storage container A, the opening of which is closed with the first lid 2, and the nozzle-shaped opening at the tip of the first lid 2. The feces storage container A is handed to the subject with the container closed with the second lid 3. At this time, a fecal collection stick 6 (preferably two or more) is also handed to the subject. The subject who has received the stool collection rod 6 and the stool collection container A first pierces the tip of the first stool collection rod 6 into his / her stool and rubs the groove 7 against the stool. As a result, feces are stored in the groove 7. Next, excess feces adhering to portions other than the groove 7 are wiped off with a toy paper or the like, and the feces of the volume of the groove 7 are quantitatively held at the tip of the fecal sampling rod 6. Next, stool is collected from another part of the stool in the same manner as described above using the second stool collection rod 6. Next, the feces collection rods 6 from which feces have been collected are inserted by opening the first lid 2 of the feces storage container A, and the first lid 2 closes the container body 1.

Next, the stool storage container A is delivered to the inspector by mail or other means from the subject with the stool collection rod 6 inserted, but since the stool storage container A is sealed in a liquid-tight manner, it is hygienic. It can be delivered in a safe state.

The inspector who has received the fecal collection container A gently shakes the container body, and suspends and dissolves the feces contained in the groove 7 of the feces collection rod 6 in the feces suspension liquid 5.

Next, the examiner opens the second lid 3 of the stool storage container A and presses the side of the stool storage container A in which the stool collection rod 6 is inserted to take out the liquid in which the stool is suspended. At this time, the fecal suspension in the container body 1 passes through a filter 14 provided inside the first lid 2, and insoluble components are filtered off. At this time, if the opening at the tip of the first lid 2 is formed as a drip orifice, the amount of fecal suspension to be taken out can be adjusted by adjusting the diameter of the drip. The suspension can be easily removed. In addition, the inspector does not stain his or her hands with feces or its solution after receiving feces collection container A.

FIG. 3 is a perspective view showing another embodiment of the stool collection rod of the present invention, and FIG. 4 is a side view showing a state where the lid of the stool collection container constituting the stool collection tool of the present invention is opened. FIG. 5 is a perspective view showing an example of a fecal wipe.

The feces collection rod 6 shown in Fig. 3 is the feces collection container shown in Fig. 4. After collecting the stool from 9, a groove 7 for storing the stool is provided on the side of the tip, and a stool wiping tool 8 for wiping off excess stool attached to parts other than the groove 7. Movably fitted o

The stool wiping tool 8 is made of a flexible plastic such as urethane resin, polyethylene resin, or vinyl chloride resin, or a material such as foam, paper, or non-woven cloth, and the stool collection rod 6 can be inserted therein. A cut 14 is provided, and the feces collection rod 6 is slidably fitted to the feces collection rod 6 by inserting the feces collection rod 6 into the cut 14.

The stool wiping device 8 is preferably sized to be stored in the stool collection container 9, and its shape is not particularly limited. In addition, depending on the material of the feces wiping device 8, the cuts 14 may be holes through which the feces collection rod 6 is inserted.

The feces wiping tool 8 is slidably fitted to the stool collection rod 6, but when used, the stool wiping tool 8 is fitted at the tip of the stool collection rod 6 from the tip with the groove 7 on the side. The stool wiping tool 8 is set so as to enter inside the container body 10 of the stool collection container 9.

The stool collection container 9 has a container body 10 and a lid 11, the container body 10 and the lid 11 are connected by a hinge 12, and the lid 11 has a tab 1 3 for easy opening and closing. Is provided. The container body 10 and the lid 11 may be separated separately, and a known stool collection container 9 is used.

Next, how to use the stool collection device shown in Figs. 3 to 5 will be explained. First, the examiner opens the lid 11 of the stool collection container 9 containing the stool of the subject, and inserts a tip 7 having a groove 7 on the side of the stool collection rod 6. Scrub the feces, or pierce the feces and draw a circle to collect and store the feces in the groove 7.

Next, the stool collection rod 6 is sandwiched between the container body 10 and the lid 11 of the stool collection container 9.

At this time, the part from the tip having the groove 7 on the side surface of the feces sampling rod 6 to the feces wiping tool 8 is inside the container body 10 of the feces sampling container 9. When the fecal collection stick 6 is pulled while holding the lid 11, the fecal wiper 8 slides in the direction of the groove 7, and wipes off excess feces attached to parts other than the groove 7, and finally the container. Drops into body 10. Further, pull the feces collection rod 6 and take out the feces collection rod 6 containing a certain amount of feces in the groove 7.

The stool collection container 9 containing the dropped stool wiping tool 8 is disposed of after sterilization.

In this way, the feces collected in the groove 7 of the feces collection rod 6 by the feces collection tool were prepared as a fecal suspension in the wing feces storage container A shown in Fig. 1 as described above. Is done.

By using the stool suspension preparation tool, stool collection tool and stool collection rod of the present invention, the operations of stool collection, sample preparation, and examination are easy, and the examiner's hands may be stained with stool or its suspension. No hygiene.

Further, according to the stool collection rod in which the stool wiping tool is slidably fitted, after the stool is collected in the groove at the tip of the stool collection rod, the stool wiping tool is inserted from the tip having a groove on the side surface. A simple operation of sandwiching the stool collection rod into the stool collection container between the container body and the lid of the stool collection container, and pulling the stool collection rod while holding down the lid. Wipe off excess feces attached to Feces can be collected. It is hygienic because it does not stain the hands. Experimental example 1

Three types of fecal collection rods with a width of 0.5 mm, a depth of 0.7 mm, and a width of 0 mm, a depth of 0.7 ram, and a width of 0 mm and a depth of 0.3 mm The stool was collected using, and the weight of the collected stool per two sampling rods was measured.

Table 1 shows the results.

Table 1 Groove width (ram) 0.5 1.0 1.0

Groove depth (mm) 0.7 0.7 0.3

(if depth) ratio 0.71 1.43 3.33

No. 1 6.6 10.0 3, 1

No. 2 6.6 11.4 2.2

No. 3 6.0 10.1 1.8

No. 4 6.8 9, 5 3.7

No. 5 6.6 13.0 2.3

No. 6 7.2 9.2 2.3

No. 7 6.8 10.7 3.0

No. 8 6.2 9.0 1.9

Average amount (mg) 6.6 10.4 2.5

C. V (%) 5.6 12.8 26.1 Experimental example 2

Using one or two stool collection rods of the present invention containing three grooves with a width of 0.5 mra and a groove depth of 0.7 mm, 76 cases of stool from colorectal cancer patients were collected. The stool was placed in the stool storage container of the invention (2 ml of 0.1 mol / L-glycine buffer (0.9% —NaCl, pH 8.2)). The stool was suspended and dissolved.

A 1% latex reagent consisting of polystyrene latex (0.3 μm particle size) sensitized with anti-human hemoglobin antibody, 25 H Ά Ά, and the feces lysate 100 ^ ^ mixed on an agglutination test plate After 3 minutes, the aggregation image was observed. If aggregation was observed, it was determined to be positive, and if not, it was determined to be negative. The results are shown in Table 2.

Table 2 2 sampling rods 1 sampling rod Positive 50 cases • 4 1 case Negative 2 6 cases 3 5 cases Total 7 6 cases 7 6 cases

Claims

The scope of the claims

1. A container body for storing a liquid for fecal suspension, a first lid provided at an opening of the container body, and provided with a means for filtering the fecal suspension therein, A stool storage container comprising a second lid capable of sealing an opening provided at the upper part of the first lid, and a plurality of grooves for stool collection and storage which can be stored in the stool storage container and on the side surface A feces suspension preparation tool provided with a separate feces collection rod provided.

2. A preparation for preparing a fecal suspension according to claim 1, comprising at least two fecal sampling rods.

3. The stool suspension preparation tool according to claim 1, wherein a stool wiping tool is slidably fitted on the stool collection rod.

4. The stool suspension preparation device according to claim 3, comprising a stool collection container having a lid.

5. A stool collection rod provided with a groove for collecting and storing stool on the side surface of the distal end, wherein a stool wiping tool is slidably fitted.

6. A stool collection rod provided with a stool collection and storage groove on the side of the tip, and a stool having a stool collection rod and a stool, which is characterized in that the stool wiping tool is slidably fitted. A stool tool equipped with a collection container.