WO1992004864A1 - Dispositif de surveillance - Google Patents
Dispositif de surveillance Download PDFInfo
- Publication number
- WO1992004864A1 WO1992004864A1 PCT/GB1991/001660 GB9101660W WO9204864A1 WO 1992004864 A1 WO1992004864 A1 WO 1992004864A1 GB 9101660 W GB9101660 W GB 9101660W WO 9204864 A1 WO9204864 A1 WO 9204864A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- recess
- reduced pressure
- passage
- cap
- applying
- Prior art date
Links
- 238000012806 monitoring device Methods 0.000 title claims abstract description 20
- 238000007789 sealing Methods 0.000 claims abstract description 26
- 238000012544 monitoring process Methods 0.000 claims description 15
- 210000003754 fetus Anatomy 0.000 abstract description 16
- 230000001605 fetal effect Effects 0.000 abstract description 13
- 208000037805 labour Diseases 0.000 description 5
- 238000010276 construction Methods 0.000 description 3
- 230000003287 optical effect Effects 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 210000002458 fetal heart Anatomy 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 239000004677 Nylon Substances 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 210000003679 cervix uteri Anatomy 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 239000012777 electrically insulating material Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000004816 latex Substances 0.000 description 1
- 229920000126 latex Polymers 0.000 description 1
- 229920001684 low density polyethylene Polymers 0.000 description 1
- 239000004702 low-density polyethylene Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000008774 maternal effect Effects 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000004945 silicone rubber Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
- A61B5/28—Bioelectric electrodes therefor specially adapted for particular uses for electrocardiography [ECG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
- A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
- A61B5/4343—Pregnancy and labour monitoring, e.g. for labour onset detection
- A61B5/4362—Assessing foetal parameters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/251—Means for maintaining electrode contact with the body
- A61B5/252—Means for maintaining electrode contact with the body by suction
Definitions
- This invention relates to a monitoring device and is more particularly concerned with a monitoring device which is to be attached to a fetus for monitoring during labour, eg. for ECG (electrode cardiogram), CTG (cardio- tocography), blood-oxygen level or pH, such device including one or more monitoring elements eg sensors and/or electrodes which are maintained in monitoring contact with the fetus.
- ECG electrode cardiogram
- CTG cardio- tocography
- blood-oxygen level or pH such device including one or more monitoring elements eg sensors and/or electrodes which are maintained in monitoring contact with the fetus.
- the monitoring device of the present invention has been specifically designed to be used for fetal monitoring- it will be appreciated that the device can be used for other monitoring purposes.
- Non-invasive fetal monitoring devices are known per se wherein a body of the device is held against the fetal skin by suction.
- US Patent 4299232 discloses a fetal heart rate monitoring device wherein the body takes the form of a flexible cup which is introduced into the birth canal and initially sealed with the cervix without pressing, and then the device is slid sideways to contact the fetal head and finally pressed to create suction and to cause an electrode inside the flexible cup to pierce the fetal skin.
- Such an arrangement has the disadvantage that only a relatively limited degree of suction can be applied and there is a risk that the device will become inadvertently detached from the fetal head during labour.
- US Patent 4537197 discloses a fetal oxygen monitoring device including a suction cup to hold the distal ends of optical fibres against the fetal skin.
- the optical fibres are embedded in the wall of a flexible catheter whose distal end is connected to or integral with the suction cup and whose proximal end is connected to a suction syringe to enable a reduced pressure to be applied to the interior of the cup.
- the piston of the syringe has a catch to engage the cylinder so as to maintain the reduced pressure in the suction cup.
- the device body has connections for attachment to a vacuum source to enable a partial vacuum to be created within the body and to connect the device to a vent tube.
- a reduced pressure is continuously applied to the device body, with the vent tube creating a constant flow of air through the device to control the suction pressure and to prevent clogging of the vacuum line.
- This latter type of device is relatively expensive and complicated in that it requires both a vacuum tube and a vent tube to be connected with the device body continuously during use.
- a monitoring device comprising a body, a recess within the body, a sealing edge surrounding the recess and adapted to engage sealingly against a surface to which the device is to be secured in use, a passage in the body communicating with the recess, at least one monitoring element carried by the body, and means for applying a reduced pressure to the passage,.and thereby to the recess, so as to secure the body in use to the surface with said at least one monitoring element in a predetermined position relative to said surface, characterized in that the means for applying reduced pressure is detachable from the body, and in that means are provided for sealing said passage so as to enable a reduced pressure to be maintained in the recess in use after detachment of the reduced pressure applying means.
- the means for applying reduced pressure may comprise a piston and suction tube device, the suction tube being detachably connected with said passage.
- the passage defines the suction tube and the piston itself defines the means for sealing the passage as well as for applying the reduced pressure, the piston being moveable by a mechanism, for example a piston rod and guide tube which are detachable, such arrangement being as described in my British Patent Application No. 9020983.4 filed on 26 September 1990 from which the present application claims priority and in respect of which the disclosure is incorporated herein by reference, as is the disclosure in my British Patent Application No. 9025758.5 filed 27th November 1990.
- valve means in the passage provides the means for sealing the latter.
- valve means is preferably a pressure-responsive valve closure member adapted to close when a higher negative pressure exists in the recess than in the reduced pressure applying means.
- the body of the monitoring device normally takes the form of a suction cap.
- the sealing edge is preferably smooth and convexly curved and, more preferably, merges with the main part of the outer periphery of the body through the intermediary of a shallow annular concave region.
- the sealing edge may alternatively, or preferably additionally, merge smoothly with the inner recess via a convex region which merges smoothly with an inner concave region.
- Such concave region(s) is/are found to reduce the amount of negative pressure required to keep the body in place in use.
- the suction tube may comprise an elongate tube which has a vent orifice intermediate its ends arranged so that the tube is vented when the piston has been moved a predetermined distance in a suction-applying direction.
- the valve means it is preferred to arrange for the valve means to close automatically as a result of the differential pressure applied thereacross when the piston has moved past the vent hole in the suction-applying direction.
- Said at least one monitoring element may be provided in the region of the sealing edge and, more particularly, may define at least part of the sealing edge. However, it is within the scope of the present invention, and may be preferable in some cases, for said at least one monitoring element to be disposed on the outside of the body, ie away from the area of negative pressure.
- abutment means In the case where the surface against which the body is to seal is a flexible surface, eg fetal tissue, it is preferred for abutment means to be provided within the recess for limiting deformation of the surface into the recess.
- FIG. 1 is a top plan view of part of a monitoring device according to the present invention
- Fig. 2 is an axial section of the part shown in Fig. 1,
- Fig. 3 is an underneath plan view of the part shown in Fig. 1,
- Fig. 4 is an axial section through another part of the monitoring device.
- Figs. 5a, 5b and 5c are sections showing the positions in which the valve disk illustrated in Fig. 2 can adopt under various conditions.
- the part of the monitoring device illustrated therein is that which is intended to be anchored to the presenting part of the fetus (usually the fetal head) to secure a CTG pick-up electrode thereto for monitoring of the fetus during labour.
- the device comprises a body in the form of an electrode cap 10 moulded from an electrically insulating material (eg PVC) and including an internal electrode 12 for CTG monitoring.
- the electrode 12 is formed of an electrically conductive material (eg stainless steel) and has an insulated electrical lead 13 connected thereto for transmitting signals from the electrode to remote analysis equipment (also not shown).
- the lead 13 has a stainless steel collar 13a thereon which acts as a reference electrode for contact with the maternal tissue and which is connected via its own lead (also not shown) to the analysis equipment.
- the cap 10 and electrode 12 together define an annular, smooth, convexly curved sealing edge 14 surrounding a recess 16 within the cap 10 and electrode 12.
- the majority of the external peripheral surface of the cap 10 is convexly curved but is formed with a shallow annular concave region 17 at its junction with the sealing edge 14.
- the sealing edge 14 merges smoothly with the inner surface of the recess 16 which has an annular undercut region 19.
- the region 19 is smooth and concavely curved.
- the surface of the cap 10 presented away from the recess 16 includes a circular boss 18 with surrounding annular groove 20 having an annular sealing washer 21 therein formed of a suitable material such as latex.
- the boss 18 is hollow and is provided with an outer end wall 22 having a plurality (in this embodiment, three) of holes 24 therein which are spaced apart across the diameter thereof.
- the interior of the boss 18 opens into the recess 16 but is closed by a moulded resin insert 26 which is sealingly secured in position.
- the insert 26 has an axial passage 28 therethrough with cross-passages 30 extending radially therefrom to the outer periphery of the insert 26.
- valve chamber 32 in which is disposed a valve disk 34 formed, in this embodiment, of a filled silicone rubber.
- the diameter of the disk 34 is about three quarters that of the chamber 32 and so is less than that of the chamber 32 but large enough to cover axial passage 28.
- That surface of the insert 26 which is presented to the valve chamber 32 defines a valve seat against which the valve disk 34 is sealingly engageable.
- the hollow boss 18 with holes 24 therethrough, the valve chamber 32 and the insert 26 with passages 28 and 30 therein together, in effect, define a passage in the body of the monitoring device, such passage communicating with the recess 16.
- the valve disk 34 and upper surface of the insert 26 together define in effect a means for sealing such passage.
- the monitoring device further includes an elongate guide tube 36 of circular cross-section with a diameter and wall thickness such that its lower end (as viewed in Fig. 4) is a close but detachable fit within the annular groove 20 in cap 10.
- a piston 38 Disposed within the guide tube 36 is a piston 38 fitted with an 0-ring seal 40 which seals against the internal surface of the guide tube 36.
- the piston 38 is carried by a piston shaft 42 which extends throughout and projects from the upper end (not shown) of the guide tube 36.
- the piston shaft is hollow, but it may be solid if desired.
- the guide tube 36 is formed of nylon to provide a degree of rigidity with some flexibility, and is slightly curved (not shown) over a distal end region thereof to facilitate introduction into the birth canal.
- the piston 38 is formed of PVC, whilst the piston shaft 42 is formed of low density polyethylene and is more flexible than the guide tube 36. This is to make the assembly easy to handle.
- the wall of the guide tube 36 has a vent hole 44 therethrough at a location which is spaced from the lower end of the guide tube 36 by a distance sufficient to give the required degree of suction within the recess 16 as will be described hereinafter.
- the part of the monitoring device described and illustrated with reference to Figs.1 to 3 above is engaged with and supported by the guide tube 36 with the lower (or distal) end of the latter frictionally engaged in the annular groove 20 and sealed against the washer 21 therein.
- Temporary securing of the guide tube 36 to the cap 10 is further assisted by clipping the electrode leads 13 temporarily in a suitably shaped retaining notch 52 in a handle 54 at the proximal end of the piston rod 42.
- an axial recess may be provided in the outer surface of the guide tube 36 to receive the leads 13, or a separate tube (also not shown) may be provided for containing the leads.
- the guide tube 36 can then be used to introduce the cap 10 into the birth canal so as to bring the sealing edge 14 directly into contact with the tissue 50 (see Fig. 2) of the presenting part of the fetus, which will normally be the fetal head.
- the leads 13 are then disengaged from the notch 52 and, whilst holding the cap 10 in position using the tube 36, and with the piston 38 in a forward position (as shown in Fig. 4), the piston shaft 42 is then pulled back using the handle 54.
- This exerts a reduced pressure within the lower end of the guide tube 36 which causes the valve disk 34 to move from its rest position (Fig. 5a) into an opened position (Fig. 5b) which allows a reduced pressure to be applied to the chamber 16.
- Fig. 2 This causes the fetal tissue 50 to be drawn into the recess 16 and to seal effectively against the sealing edge 14 as shown in Fig. 2 where it will be seen that the fetal tissue 50 is pulled partially up into the recess 16 to enter the concave region 19 thereof. Undue stretching of the fetal tissue 50 and complete filling of the recess 16 is prevented by reason of engagement of the tissue against the lower surface of the insert 26 (as viewed in Fig. 2). Once the fetal tissue 50 has been partially drawn into the recess 16, an oede atous response (swelling with fluid) occurs and this fills the cup to the required extent.
- the cross passages 30 allow a negative pressure to be distributed over a large area of fetal tisssue 50 and ensures that a good electrical contact is maintained with the electrode 12.
- the cap 10 can be removed by carefully pressing a small region of the fetal tissue 50 away from the sealing edge 12 to relieve the reduced pressure within the recess 16. It will be appreciated that the provision of the holes 24 across the diameter of the wall 20 of the boss 18 ensures that the valve disk 34 can never completely seal the holes 24 whilst suction is being applied (as shown in Fig. 5b).
- the use of the electrode 12 to form part of the sealing edge 14 ensures that there is always an effective contact maintained between the electrode 12 and the fetal tissue 50 whilst the device is in use.
- the monitoring device is used for CTG purposes.
- the electrode 12 can be used mutatis mutandis for other purposes if desired.
- more than one electrode may be provided and that each of such electrodes may have portioned defining part of the sealing edge 14.
- further electrodes may be provided externally of the cap 10.
- the cap 10 may also be used to support any other type of sensor, for example, for pH or oxygen monitoring simply by providing appropriate sensors within the recess 16 or outside the cap 10.
- the distal end of the guide tube 36 engages in the groove 20 and extends rearwardly substantially axially of the cap 10.
- the guide tube 36 is connected with the cap 10 through the intermediary of a small adapter body which fits over part of the rear of the cap 10 and has an internal sleeve which loosely engages in the groove 20.
- the adapter body has an external, rearwardly presented recess by means of which finger pressure can be applied to ensure flush engagement of the cap 10 with the fetal tissue and to facilitate steadying of the cap 10 during fitting.
- the adapter body also has a passage therein which communicates with the holes 30 and which extends rearwardly and laterally of the adapter body to pass through an external circular boss which extends rearwardly at an angle, of about 45 degrees relative to the axis of the cap 10.
- the guide tube 36 frictionally engages over this boss and so extends in a direction which more easily permits a finger to be inserted to press the cap 10 into position without bending the guide tube 36 during fitting of the cap 10. Finger pressure on the adapter body can be continued in order to hold the cap 10 in the correct position whilst reduced pressure is being applied.
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Gynecology & Obstetrics (AREA)
- Pediatric Medicine (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Cardiology (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
Un dispositif de surveillance f÷tale comprend une coiffe (10) pourvue d'une électrode interne (12) et d'un évidement (16). Un bord d'étanchéité (14) qui se plaque, de façon étanche, contre le tissu f÷tal (50), lorsqu'on utilise le dispositif, est créé par la coiffe (10) et l'électrode (12). On applique une pression réduite à l'intérieur de l'évidement (16) au moyen d'un dispositif à piston (38, 40) et cylindre (36), par des orifices (24), une chambre de soupape (32), un passage (28) et des passages transversaux (30). Une tête de soupape (34) obture le passage (28) pour maintenir l'étanchéité de l'évidement (16), pendant l'utilisation et après le retrait du dispositif à piston et cylindre.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909020983A GB9020983D0 (en) | 1990-09-26 | 1990-09-26 | Fetal monitor suction probe |
GB9020983.4 | 1990-09-26 | ||
GB909025758A GB9025758D0 (en) | 1990-09-26 | 1990-11-27 | Fetal monitor suction probe |
GB9025758.5 | 1990-11-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1992004864A1 true WO1992004864A1 (fr) | 1992-04-02 |
Family
ID=26297712
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB1991/001660 WO1992004864A1 (fr) | 1990-09-26 | 1991-09-26 | Dispositif de surveillance |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU8653291A (fr) |
WO (1) | WO1992004864A1 (fr) |
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0676170A1 (fr) * | 1994-04-04 | 1995-10-11 | Graphic Controls Corporation | Sonde à foetus noninvasiblée |
US5833622A (en) * | 1994-04-04 | 1998-11-10 | Graphic Controls Corporation | Non-invasive fetal probe having improved mechanical and electrical properties |
US7794474B2 (en) | 1996-08-22 | 2010-09-14 | The Trustees Of Columbia University In The City Of New York | Endovascular flexible stapling device |
US7914527B2 (en) | 2003-03-27 | 2011-03-29 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US7922716B2 (en) | 2003-03-27 | 2011-04-12 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of anatomic tissue defects |
US7972330B2 (en) | 2003-03-27 | 2011-07-05 | Terumo Kabushiki Kaisha | Methods and apparatus for closing a layered tissue defect |
US8021362B2 (en) | 2003-03-27 | 2011-09-20 | Terumo Kabushiki Kaisha | Methods and apparatus for closing a layered tissue defect |
US8038672B2 (en) | 2003-03-27 | 2011-10-18 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US8052678B2 (en) | 2003-03-27 | 2011-11-08 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US8057469B2 (en) | 2003-03-27 | 2011-11-15 | Terumo Kabushiki Kaisha | Methods and apparatus for treatment of patent foramen ovale |
US8109274B2 (en) | 2005-04-11 | 2012-02-07 | Terumo Kabushiki Kaisha | Methods and electrode apparatus to achieve a closure of a layered tissue defect |
US8133221B2 (en) | 2004-06-21 | 2012-03-13 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of anatomic tissue defects |
CN102961128A (zh) * | 2012-10-28 | 2013-03-13 | 思澜科技(成都)有限公司 | 一种医用体表电极 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2580628A (en) * | 1950-07-12 | 1952-01-01 | Bowen & Company Inc | Suction electrode |
FR1139191A (fr) * | 1955-01-17 | 1957-06-26 | Ateliers Mecaniques De Pont Su | Dispositif d'électrodes pour le massage et l'électrothérapie |
US4217908A (en) * | 1978-10-16 | 1980-08-19 | Bernard B. Staver | Vector lead apparatus and methods of constructing and utilizing same |
DE8907755U1 (de) * | 1989-06-24 | 1989-09-14 | Metronic Electronic GmbH, 7210 Rottweil | Elektromedizinische Saugelektrode |
-
1991
- 1991-09-26 AU AU86532/91A patent/AU8653291A/en not_active Abandoned
- 1991-09-26 WO PCT/GB1991/001660 patent/WO1992004864A1/fr active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2580628A (en) * | 1950-07-12 | 1952-01-01 | Bowen & Company Inc | Suction electrode |
FR1139191A (fr) * | 1955-01-17 | 1957-06-26 | Ateliers Mecaniques De Pont Su | Dispositif d'électrodes pour le massage et l'électrothérapie |
US4217908A (en) * | 1978-10-16 | 1980-08-19 | Bernard B. Staver | Vector lead apparatus and methods of constructing and utilizing same |
DE8907755U1 (de) * | 1989-06-24 | 1989-09-14 | Metronic Electronic GmbH, 7210 Rottweil | Elektromedizinische Saugelektrode |
Cited By (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0676170A1 (fr) * | 1994-04-04 | 1995-10-11 | Graphic Controls Corporation | Sonde à foetus noninvasiblée |
US5474065A (en) * | 1994-04-04 | 1995-12-12 | Graphic Controls Corporation | Non-invasive fetal probe |
US5665477A (en) * | 1994-04-04 | 1997-09-09 | Graphic Controls Corporation | Hydrogel adhesive for attaching medical device to patient |
US5833622A (en) * | 1994-04-04 | 1998-11-10 | Graphic Controls Corporation | Non-invasive fetal probe having improved mechanical and electrical properties |
US7794474B2 (en) | 1996-08-22 | 2010-09-14 | The Trustees Of Columbia University In The City Of New York | Endovascular flexible stapling device |
US9468437B2 (en) | 1996-08-22 | 2016-10-18 | The Trustees Of Columbia University In The City Of New York | Endovascular flexible stapling device |
US8167905B2 (en) | 1996-08-22 | 2012-05-01 | The Trustees Of Columbia University In The City Of New York | Endovascular flexible stapling device |
US8048110B2 (en) | 1996-08-22 | 2011-11-01 | The Trustees Of Columbia University In The City Of New York | Endovascular flexible stapling device |
US8038669B2 (en) | 2003-03-27 | 2011-10-18 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US8070747B2 (en) | 2003-03-27 | 2011-12-06 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US8038673B2 (en) | 2003-03-27 | 2011-10-18 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US8038671B2 (en) | 2003-03-27 | 2011-10-18 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US8021362B2 (en) | 2003-03-27 | 2011-09-20 | Terumo Kabushiki Kaisha | Methods and apparatus for closing a layered tissue defect |
US7972330B2 (en) | 2003-03-27 | 2011-07-05 | Terumo Kabushiki Kaisha | Methods and apparatus for closing a layered tissue defect |
US8052678B2 (en) | 2003-03-27 | 2011-11-08 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US8057469B2 (en) | 2003-03-27 | 2011-11-15 | Terumo Kabushiki Kaisha | Methods and apparatus for treatment of patent foramen ovale |
US8066701B2 (en) | 2003-03-27 | 2011-11-29 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US8038672B2 (en) | 2003-03-27 | 2011-10-18 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US8075554B2 (en) | 2003-03-27 | 2011-12-13 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US7914527B2 (en) | 2003-03-27 | 2011-03-29 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of patent foramen ovale |
US8852181B2 (en) | 2003-03-27 | 2014-10-07 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of anatomic tissue defects |
US7922716B2 (en) | 2003-03-27 | 2011-04-12 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of anatomic tissue defects |
US8133221B2 (en) | 2004-06-21 | 2012-03-13 | Terumo Kabushiki Kaisha | Energy based devices and methods for treatment of anatomic tissue defects |
US8109274B2 (en) | 2005-04-11 | 2012-02-07 | Terumo Kabushiki Kaisha | Methods and electrode apparatus to achieve a closure of a layered tissue defect |
CN102961128A (zh) * | 2012-10-28 | 2013-03-13 | 思澜科技(成都)有限公司 | 一种医用体表电极 |
Also Published As
Publication number | Publication date |
---|---|
AU8653291A (en) | 1992-04-15 |
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