WO1991016087A1 - Procede et dispositif de detection de bulles de gaz dans des conduits remplis de liquide, notamment des conduits ou conteneurs tubulaires flexibles - Google Patents

Procede et dispositif de detection de bulles de gaz dans des conduits remplis de liquide, notamment des conduits ou conteneurs tubulaires flexibles Download PDF

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Publication number
WO1991016087A1
WO1991016087A1 PCT/EP1991/000760 EP9100760W WO9116087A1 WO 1991016087 A1 WO1991016087 A1 WO 1991016087A1 EP 9100760 W EP9100760 W EP 9100760W WO 9116087 A1 WO9116087 A1 WO 9116087A1
Authority
WO
WIPO (PCT)
Prior art keywords
line
transmitter
receiver
liquid
detection device
Prior art date
Application number
PCT/EP1991/000760
Other languages
German (de)
English (en)
Inventor
F. Baldo Veracchi
Original Assignee
Infurex Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Infurex Ag filed Critical Infurex Ag
Publication of WO1991016087A1 publication Critical patent/WO1991016087A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3626—Gas bubble detectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/02—Analysing fluids
    • G01N29/032—Analysing fluids by measuring attenuation of acoustic waves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/22—Details, e.g. general constructional or apparatus details
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/22—Details, e.g. general constructional or apparatus details
    • G01N29/222—Constructional or flow details for analysing fluids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3375—Acoustical, e.g. ultrasonic, measuring means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/01—Indexing codes associated with the measuring variable
    • G01N2291/015—Attenuation, scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/02—Indexing codes associated with the analysed material
    • G01N2291/024—Mixtures
    • G01N2291/02433—Gases in liquids, e.g. bubbles, foams
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/10—Number of transducers
    • G01N2291/105—Number of transducers two or more emitters, two or more receivers

Definitions

  • Liquid-filled lines especially flexible, tubular lines or containers
  • the invention relates to a method and a device for detecting gas bubbles in lines filled with liquid, such as, in particular, flexible lines or tubular containers as used, for example, in medical technology.
  • air detection devices are provided which work on a photoelectric basis.
  • a method and a device according to the preamble of claims 1 and 11 is known from US-A-4,607,520.
  • large numbers of signal or energy surges are sent through the liquid in the line to be examined. If, for example, an air bubble contained in the liquid to be examined passes the detection device of the known device, no received signal is recorded.
  • the disadvantage of the generic method and the generic device is that mechanical stress is placed on the liquid to be examined, which, for example in the case of blood, leads to an increased risk of hemolysis.
  • investigations carried out within the scope of the invention have shown that the measuring sections of the generic device tend to instability, which in turn can lead to incorrect measurements and the like.
  • a transmission pulse of a certain height and duration is triggered and a reception pulse of a certain height and within a certain time is expected.
  • This dynamic process enables the distinction to be made as to whether the line is filled with liquid or not, or whether only the outer walls of the line are moist, which, if the received pulse is of the same magnitude, results in a response time which starts later.
  • the detection of a gas bubble takes place in that the transmission pulse is more weakened when a gas bubble is present than when the line is completely filled with liquid.
  • a single pulse of high energy and defined form is sent from one side of the line and for the duration of a certain window, which is coordinated with the duration of the transmission pulse, on the other side of the line receive.
  • One of the particular advantages of the method according to the invention is that it offers the possibility of distinguishing gas bubbles of different sizes, so that gas bubbles of unobjectionable size can pass through, while gas bubbles of a size relevant to the respective application, for example trigger an alarm or block the line to interrupt the liquid flow.
  • the frequency of the transmission pulse should expediently be adapted to the delivery rate, which simplifies the detection of the bubble length without mechanical stress on the medium carried in the line.
  • the response time to the emitted pulses is related to the respective flow rate of the liquid to be examined. If two spaced measuring sections are provided, the bubble length is determined by first determining the simultaneous response of both measuring sections for a certain period of time, which in other words means that there is a bubble of a length which is at least the distance between the two Corresponds to measuring distances. Therefore, depending on the application, the distance between the two measuring sections can advantageously be adapted to the respective conditions and needs, so that a critical minimum bubble length can be set by the distance between the measuring sections, in the presence of which, for example, an alarm is triggered or the line is blocked.
  • the absolute bubble length can be determined by determining two time spans, the first of which indicates the time during which both measuring sections respond to the presence of a bubble, and the second Time period indicates the time that elapses after the first measuring section, as seen in the direction of flow, is deactivated, until the time at which the gas bubble leaves the second measuring section, so that it no longer emits display signals.
  • the absolute bubble length can then be determined from the sum of the first and second time span in connection with the determined flow velocity, which in many cases represents a known variable.
  • the method according to the invention can carry out a bubble count, the sequential excitation of both measurement sections indicating that the respective bubble or bubbles have actually passed both measurement points, whereas a bubble which oscillates in the line section between the measurement points or measurement sections, is not registered in the count.
  • a particularly preferred mode of generation for the transmit and receive pulses is acoustic signals, the particular advantage of the individual pulse generation being that mechanical stress on the liquid to be examined is avoided, as would otherwise be the case, for example, by permanent sonication, particularly at low levels Flow rates would be expected. Moreover, the acoustic individual pulse generation has the advantage that the measuring sections are very stable, which helps to avoid triggering false alarms.
  • the device according to the invention it is advantageously possible, owing to the arrangement of the transmitter and the receiver on opposite sides of the line and the support of the transceiver on the outer surface of the line, to send out individual pulses of the previously described type and while the duration of a predeterminable reception window to be received and evaluated.
  • the device according to the invention therefore provides the same advantages as the method according to the invention.
  • the device according to the invention By selecting the distance between the " transmitter and receiver, it is also possible in the device according to the invention to deform the line, which preferably consists of flexible compressible material, at the measuring points in such a way that the distance between the transmitter and receiver is smaller , as the dimension of the line in the relaxed state. This results in a reduction in the travel distance for the sensor designal, which contributes the advantages described above enables the detection and evaluation of the existing conditions.
  • the deformation of the line advantageously results in a pair of opposing, essentially parallel and planar contact surfaces, the width of which is preferably greater than the width of the transmitter and receiver.
  • the correct setting of the width of the transmitter and receiver relative to the line ensures that a bypass is created when the line surface is moist, but the path of which is significantly longer than the path through the inside of the line, so that a correspondingly received signal, possibly same signal level and shape, but is only received after a significantly longer response time.
  • the detection device of the device according to the invention can have two transmitting / receiving devices, the spacing of which along the longitudinal axis of the line can be adjusted depending on the application and boundary conditions.
  • the detection device can have two transmitting / receiving devices, the spacing of which along the longitudinal axis of the line can be adjusted depending on the application and boundary conditions.
  • the device according to the invention preferably has an acoustic detection device with acoustic transmitter / receiver units which emit individual acoustic signals, the signal shape and level of which can be set according to the principles of the method according to the invention. In this case, signal reception and evaluation also take place according to the principles explained above.
  • FIG. 1 is a schematically highly simplified illustration of a longitudinal section through a line which is provided with an air bubble detection device according to the invention
  • Fig. 2 is a representation corresponding to FIG. 1
  • Fig. 4 shows a receive pulse when the line is empty
  • FIG. 5 shows the representation of a receive pulse when the line is filled.
  • 1 shows a device 1 according to the invention for detecting gas bubbles in a liquid which is guided in a line 2.
  • the line 2 can in principle be part of a device or device from all the technical or medical fields in which gas bubbles can occur in flowing liquids and in which the occurrence of such gas bubbles can lead to complications, so that detection is required ⁇ is.
  • the occurrence of gas bubbles in the medical field is particularly problematic, for example in the case of arterial or venous infusion, since even the smallest amounts can lead to considerable damage to the patient and even death.
  • the use of the device according to the invention is not restricted to the medical field, so that the line 2 can in principle be any type of preferably flexible and tubular line or container.
  • the device 1 according to the invention has a detection device which is arranged outside the line 2 and which, for example, has two transmitting / receiving devices 3 and 4 which are arranged at a preselectable distance from one another along the longitudinal axis L of the line 2.
  • the transmitting / receiving device 3 forms a first measuring section
  • the transmitting / receiving device 4 represents a second measuring section.
  • the detection device of the device 1 also has the usually required energy sources, a pulse generator, an alarm device and evaluation and display units, which are schematically symbolized by block 5 in FIG. 1.
  • a schematically simplified shut-off device 6, which is arranged downstream of the second measuring section 4 in the flow direction F, is provided, which can comprise, for example, two shut-off swords 7 and 8, which If necessary, completely close line 2.
  • the shut-off device 6 can be part of the detection device and can be controlled as a function of the detection of air bubbles in the line 2 and can therefore be actuated to shut off the line 2.
  • each transmitting / receiving device 3, 4 has a transmitter 9 or 10 and a receiver 11 or 12 arranged opposite it.
  • the transmitting / receiving devices 3 and 4 are acoustic measuring sections which emit individual pulses of a defined shape and height and, with their receivers 11 and 12, these due to the presence or absence of gas bubbles receive more or less weakened signals according to a predetermined reception window.
  • the transmitters 9, 10 and receivers 11, 12 are each arranged on opposite sides of the line 2, as can be seen from FIG. 1 and from the individual illustration of FIG. 2.
  • Transmitter 9, 10 and receiver 11, 12 lie on the outer surface of line 2 and press them together at the measuring points in the manner shown in FIGS. 1 and 2.
  • support wall regions 13 and 14 (FIG. 2) are formed which are essentially flat and are aligned parallel to one another. From FIG. 2, which is representative of both transmission / reception devices 3, 4, it is clear that this results in a compression of line 2, which "means the distance between the transmitter and receiver of the respective transmission / reception device 3 , 4 reduced in comparison to the dimension of the line when not compressed.
  • FIG. 2 further clarifies that the width of the transmitter and receiver is less than the width of the support wall areas 13, 14. This ensures that A pulse must pass through the outer wall of the line 2 via a bypass, which corresponds to the curved edge areas 15 and 16, respectively, which is considerably longer than the direct path between the transmitter and receiver perpendicular to the support wall areas 13 and 14.
  • the transmitter 9 has a membrane 17 and a piezo disk 18 which is connected to the membrane 17. This arrangement can e.g. be positioned on the line 2 by means of a suitable base body.
  • the transmitter 9 can be connected to a high-voltage pulse generator, not shown in FIG. 2.
  • the receiver 11 is constructed in a corresponding manner.
  • two acoustic earth / reception devices 3 and 4 are formed, which can be operated according to the principles of the inventive method explained at the beginning.
  • FIGS. 3-5 The type of generation of the transmit / receive pulses is illustrated in FIGS. 3-5, FIG. 4 illustrating a receive pulse when the line is empty, while FIG. 5 shows the receive pulse when the line is full.
  • the dashed lines here show that it is also possible to send out only a part of a previously generated total pulse (which can be cut with respect to its shape, height and duration, so to speak) as a transmission pulse.
  • the detection device of the device 1 according to the invention also has a bubble counting device and a determination device for the bubble length, which are also symbolized by block 5.
  • the length of a bubble passing line 2 in the direction of arrow F is to be determined, a determination is first made through the first measuring section 3 and, after the bubble has reached the measuring section 4, so that both measuring sections 3 and 4 open address the presence of a blister.
  • the time during which both measuring sections 3 and 4 respond is registered as the first time period.
  • the first measuring section 3 is deactivated, that is to say the bubble has left the measuring section 3, there is a time count which determines a second time period during which the second measuring section 4 still indicates the presence of the bubble.
  • the absolute bubble length can then be determined from the sum of the first and second time periods determined in this way and the usually known flow velocity.
  • a critical minimum size can be set by selecting the distance between the measuring sections 3 and 4, when detected, for example, an alarm in block 5 or a shut-off of the line by the shut-off device 6 can be triggered.
  • This alarm and shut-off is particularly important in the medical field, for example when an infusion is carried out and the air is detected shortly before the line 2 enters the patient, so that an immediate shut-off can take place if a critical bubble size occurs or number has been determined.
  • the device according to the invention thus has the advantage that both quantitative and qualitative detection of gas bubbles in lines filled with liquid is possible.
  • a critical bubble length can also be determined by setting a critical number of pulses. For this, z. B. the critical pulse number depending on the respective flow rate is set on a scaled switch. Then this setting is compared by comparison with the determined number of pulses. If this is below the set number of pulses, the bubble length is tolerable; in the opposite case, the line is alarmed or blocked.
  • Particularly preferred embodiments of the invention are listed under items 1-20:
  • Method according to one of the items 4-6 in which, for counting individual bubbles of a size which is smaller than the distance between the measuring points, it is determined whether the two measuring points sequentially detect the presence of a bubble, and that the bubble passage are counted by the signals representing the second measuring point. 8. The method according to any one of items 1-7, in which an alarm is triggered as a function of adjustable maximum values for bubble number and bubble size if at least one of these maximum values is exceeded.
  • a detection device arranged outside the line (2) with at least one transmitting / receiving device (3, 4) which has a transmitter (9 or 10) and a receiver (11 or 12),
  • the transmitter (9, 10) is arranged on one side of the line (2) and the receiver (11, 12) on the other diametrically opposite side of the line (2),
  • the detection device is designed as a single pulse detection device.
  • the detection device has two transmitting / receiving devices (3, 4) which are arranged at a selectable distance from one another along the longitudinal axis (L) of the line (2).
  • the detection device further comprises a device for determining the absolute bubble length, which relates the response time to the flow velocity (F) of the fluid carried in the line.
  • the detection device further comprises an alarm device.
  • a shut-off device (6) is provided which, in the event of an alarm, depending on the detection of bubbles of critical size or number, the line (2) for blocking the Fluid flow blocks.
  • the transmitting / receiving device (3, 4) are designed as acoustic air detectors.
  • the device according to item 19 in which the transmitters (9, 10) and receivers (11, 12) are provided with piezo elements for generating the transmit pulses or receive pulses.

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Anesthesiology (AREA)
  • Acoustics & Sound (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)

Abstract

Un procédé et un dispositif (1) permettent de détecter des bulles de gaz dans des conduits (2) flexibles remplis de liquide. Des émetteurs/récepteurs (3, 4) sont agencés des deux côtés du conduit (2) et émettent des impulsions individuelles ayant des hauteur et forme déterminées qui sont attendues, pendant une période déterminée sous forme d'impulsions de réception ayant des hauteur et forme déterminées, par les récepteurs correspondants (11, 12).
PCT/EP1991/000760 1990-04-26 1991-04-19 Procede et dispositif de detection de bulles de gaz dans des conduits remplis de liquide, notamment des conduits ou conteneurs tubulaires flexibles WO1991016087A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4013402A DE4013402C2 (de) 1990-04-26 1990-04-26 Verfahren und Vorrichtung zur Erkennung von Gasblasen in einer mit Flüssigkeit gefüllten Leitung, insbesondere einer flexiblen, schlauchförmigen Leitung oder einem Container
DEP4013402.4 1990-04-26

Publications (1)

Publication Number Publication Date
WO1991016087A1 true WO1991016087A1 (fr) 1991-10-31

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WO (1) WO1991016087A1 (fr)

Cited By (30)

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WO1993015397A1 (fr) * 1992-01-23 1993-08-05 Cobe Laboratories, Inc. Procede et appareil de detection de bulles d'air dans des tubes
WO1994027142A1 (fr) * 1993-05-19 1994-11-24 Flueh Gerd Procede et dispositif de reconnaissance de corps etrangers dans des denrees alimentaires visqueuses ou fluides contenant des substances en morceaux
WO1996021151A1 (fr) * 1995-01-05 1996-07-11 Debiotech S.A. Dispositif de controle de l'ecoulement d'un liquide dans une conduite tubulaire et notamment dans une pompe peristaltique
EP0778465A1 (fr) * 1995-12-06 1997-06-11 Kodak Limited Détecteur de bulles
US6142008A (en) * 1998-06-12 2000-11-07 Abbott Laboratories Air bubble sensor
US6231320B1 (en) 1998-06-12 2001-05-15 Abbott Laboratories Drug infusion pumping cassette latching mechanism
US8801656B2 (en) 2012-10-29 2014-08-12 Hospira, Inc. Fluid flow passage to improve air-in-line detection
US9995611B2 (en) 2012-03-30 2018-06-12 Icu Medical, Inc. Air detection system and method for detecting air in a pump of an infusion system
US10022498B2 (en) 2011-12-16 2018-07-17 Icu Medical, Inc. System for monitoring and delivering medication to a patient and method of using the same to minimize the risks associated with automated therapy
US10046112B2 (en) 2013-05-24 2018-08-14 Icu Medical, Inc. Multi-sensor infusion system for detecting air or an occlusion in the infusion system
US10143795B2 (en) 2014-08-18 2018-12-04 Icu Medical, Inc. Intravenous pole integrated power, control, and communication system and method for an infusion pump
US10166328B2 (en) 2013-05-29 2019-01-01 Icu Medical, Inc. Infusion system which utilizes one or more sensors and additional information to make an air determination regarding the infusion system
US10342917B2 (en) 2014-02-28 2019-07-09 Icu Medical, Inc. Infusion system and method which utilizes dual wavelength optical air-in-line detection
US10430761B2 (en) 2011-08-19 2019-10-01 Icu Medical, Inc. Systems and methods for a graphical interface including a graphical representation of medical data
US10463788B2 (en) 2012-07-31 2019-11-05 Icu Medical, Inc. Patient care system for critical medications
US10596316B2 (en) 2013-05-29 2020-03-24 Icu Medical, Inc. Infusion system and method of use which prevents over-saturation of an analog-to-digital converter
US10635784B2 (en) 2007-12-18 2020-04-28 Icu Medical, Inc. User interface improvements for medical devices
US10656894B2 (en) 2017-12-27 2020-05-19 Icu Medical, Inc. Synchronized display of screen content on networked devices
US10850024B2 (en) 2015-03-02 2020-12-01 Icu Medical, Inc. Infusion system, device, and method having advanced infusion features
US10918787B2 (en) 2015-05-26 2021-02-16 Icu Medical, Inc. Disposable infusion fluid delivery device for programmable large volume drug delivery
US11135360B1 (en) 2020-12-07 2021-10-05 Icu Medical, Inc. Concurrent infusion with common line auto flush
USD939079S1 (en) 2019-08-22 2021-12-21 Icu Medical, Inc. Infusion pump
US11213619B2 (en) 2013-11-11 2022-01-04 Icu Medical, Inc. Thermal management system and method for medical devices
US11246985B2 (en) 2016-05-13 2022-02-15 Icu Medical, Inc. Infusion pump system and method with common line auto flush
US11278671B2 (en) 2019-12-04 2022-03-22 Icu Medical, Inc. Infusion pump with safety sequence keypad
US11324888B2 (en) 2016-06-10 2022-05-10 Icu Medical, Inc. Acoustic flow sensor for continuous medication flow measurements and feedback control of infusion
US11344668B2 (en) 2014-12-19 2022-05-31 Icu Medical, Inc. Infusion system with concurrent TPN/insulin infusion
US11344673B2 (en) 2014-05-29 2022-05-31 Icu Medical, Inc. Infusion system and pump with configurable closed loop delivery rate catch-up
WO2023057218A1 (fr) * 2021-10-08 2023-04-13 Endress+Hauser Flowtec Ag Procédé de distinction entre la présence d'un corps étranger ou d'une bulle de gaz dans un milieu, et système correspondant
US11883361B2 (en) 2020-07-21 2024-01-30 Icu Medical, Inc. Fluid transfer devices and methods of use

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DE4435594C2 (de) * 1994-10-05 1996-08-14 Hans Rattay Verfahren zum Detektieren von insbesondere Gas in flüssigen Medien transportierenden Leitungen und Vorrichtung zur Durchführung des Verfahrens
FI104447B (fi) 1998-07-10 2000-01-31 Valmet Automation Inc Menetelmä ja mittalaite nestemäisen aineen kaasupitoisuuden mittaamiseksi
ITTO20011222A1 (it) 2001-12-27 2003-06-27 Gambro Lundia Ab Apparecchiatura per il controllo di flusso sanguigno in un circuito-extracorporeo di sangue.
ITMI20020359A1 (it) 2002-02-22 2003-08-22 Gambro Lundia Ab Metodo di controllo dell'operativita' di un organo di interdizione del flusso e dispositivo di arresto del flusso per un circuito extracorpo
JP4443957B2 (ja) 2003-04-28 2010-03-31 株式会社根本杏林堂 漏出検出装置および方法
DE102005025515A1 (de) 2005-06-03 2006-12-07 Fresenius Medical Care Deutschland Gmbh Verfahren und Vorrichtung zum Überwachen einer strömenden Flüssigkeit auf das Vorhandensein von Luft
EP1770379A1 (fr) * 2005-09-29 2007-04-04 JohnsonDiversey, Inc. Dispositif et mèthode pour détecter la présence d'un gaz dans un écoulement de liquide
DE102006045452B4 (de) 2006-09-26 2009-04-02 Fresenius Medical Care Deutschland Gmbh Verfahren und Vorrichtung zur Erkennung von Luft in einem Flüssigkeitssystem, insbesondere in einem extrakorporalen Blutkreislauf einer Blutbehandlungsvorrichtung
DE102009007806B4 (de) 2009-02-06 2014-06-05 Fresenius Medical Care Deutschland Gmbh Vorrichtung zur Schwingungsanregung wenigstens eines Abschnitts einer Gefäßzugangseinrichtung zu deren Überwachung
JP6856995B2 (ja) * 2016-09-15 2021-04-14 株式会社ジェイ・エム・エス 超音波センサヘッド及び該超音波センサヘッドを備える超音波検出器

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