WO1990013634A3 - Enzymes et leur utilisation pour la detection des drogues - Google Patents
Enzymes et leur utilisation pour la detection des drogues Download PDFInfo
- Publication number
- WO1990013634A3 WO1990013634A3 PCT/GB1990/000727 GB9000727W WO9013634A3 WO 1990013634 A3 WO1990013634 A3 WO 1990013634A3 GB 9000727 W GB9000727 W GB 9000727W WO 9013634 A3 WO9013634 A3 WO 9013634A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- enzymes
- morphine
- drug detection
- amce
- mdh
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/004—Enzyme electrodes mediator-assisted
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP90907336A EP0471740B1 (fr) | 1989-05-12 | 1990-05-11 | Enzymes et leur utilisation pour la detection des drogues |
US07/784,445 US5298414A (en) | 1989-05-12 | 1990-05-11 | Detection of morphine using morphine dehydrogenase |
DE69021564T DE69021564T2 (de) | 1989-05-12 | 1990-05-11 | Enzyme und deren verwendung zum nachweis von drogen. |
CA002055442A CA2055442C (fr) | 1989-05-12 | 1990-05-11 | Enzymes et leur utilisation dans la detection des drogues |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8910958.1 | 1989-05-12 | ||
GB898910958A GB8910958D0 (en) | 1989-05-12 | 1989-05-12 | Assay |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1990013634A2 WO1990013634A2 (fr) | 1990-11-15 |
WO1990013634A3 true WO1990013634A3 (fr) | 1991-05-16 |
Family
ID=10656644
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB1990/000727 WO1990013634A2 (fr) | 1989-05-12 | 1990-05-11 | Enzymes et leur utilisation pour la detection des drogues |
Country Status (9)
Country | Link |
---|---|
US (2) | US5298414A (fr) |
EP (1) | EP0471740B1 (fr) |
JP (1) | JP3045540B2 (fr) |
AU (1) | AU643687B2 (fr) |
CA (1) | CA2055442C (fr) |
DE (1) | DE69021564T2 (fr) |
GB (2) | GB8910958D0 (fr) |
HU (1) | HUT59959A (fr) |
WO (1) | WO1990013634A2 (fr) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9115765D0 (en) * | 1991-07-22 | 1991-09-04 | Britt Adrian J | Bacterial enzyme for cocaine detection |
US5846708A (en) * | 1991-11-19 | 1998-12-08 | Massachusetts Institiute Of Technology | Optical and electrical methods and apparatus for molecule detection |
GB9213524D0 (en) * | 1992-06-25 | 1992-08-12 | Macfarlan Smith Ltd | Biocatalysis in the synthesis of analgesic and antitussive compounds |
GB9622516D0 (en) | 1996-10-29 | 1997-01-08 | Univ Cambridge Tech | Enzymic cofactor cycling |
US6225074B1 (en) * | 1997-08-18 | 2001-05-01 | Dennis Wright | Direct chloramphenicol acetyl transferase assay |
WO2000057166A1 (fr) * | 1999-03-19 | 2000-09-28 | Sapporo Immuno Diagnostic Laboratory | Procede d'analyse de substrat et biocapteur |
AU2000267324A1 (en) * | 2000-08-28 | 2002-03-13 | Sapporo Immuno Diagnostic Laboratory | Method for determination of substrate and biosensor |
US20040096927A1 (en) * | 2000-09-13 | 2004-05-20 | Chittock Roger Steward | Method for the detection and measurement of biomass |
PL208060B1 (pl) * | 2001-01-09 | 2011-03-31 | Lonza Ag | Nowe mikroorganizmy Rhodococcus sp., ekstrakty enzymów wyodrębniane z tych mikroorganizmów, hydrataza nitrylowa wytwarzana przez te mikroorganizmy oraz mikrobiologiczny sposób wytwarzania amidów, jak również zastosowania tych mikroorganizmów |
US8975063B2 (en) | 2006-10-19 | 2015-03-10 | California Institute Of Technology | Compositions and methods for producing benzylisoquinoline alkaloids |
WO2013016379A1 (fr) * | 2011-07-27 | 2013-01-31 | Agamatrix, Inc. | Réactifs pour bandelettes réactives électrochimique |
EP3865580A1 (fr) * | 2013-03-15 | 2021-08-18 | The Board of Trustees of the Leland Stanford Junior University | Alcaloïdes de benzylisoquinoline (bia) produisant des microbes et leurs procédés de fabrication et d'utilisation |
CN105829541B (zh) | 2013-11-04 | 2022-08-12 | 小利兰·斯坦福大学托管委员会 | 产生苄基异喹啉生物碱(bia)前体的微生物以及制备和使用所述前体的方法 |
WO2015171839A1 (fr) * | 2014-05-08 | 2015-11-12 | South Dakota Board Of Regents | Dosage chimique pour vérifier la quantité et la qualité des dérivés de lactone de sesquiterpène |
CN107614688B (zh) | 2015-05-04 | 2023-02-28 | 小利兰·斯坦福大学托管委员会 | 产生苄基异喹啉生物碱(bia)前体的微生物及其制备和使用方法 |
DK3294865T3 (da) | 2015-05-08 | 2023-05-08 | Univ Leland Stanford Junior | Fremgangsmåder til fremstilling af epimeraser og benzylisoquinolinalkaloider |
GB2579940B (en) | 2017-08-03 | 2022-11-30 | Antheia Inc | Engineered benzylisoquinoline alkaloid epimerases and methods of producing benzylisoquinoline alkaloids |
US11773422B2 (en) * | 2019-08-16 | 2023-10-03 | Microsoft Technology Licensing, Llc | Regulation of polymerase using cofactor oxidation states |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH628009A5 (de) * | 1977-07-26 | 1982-02-15 | Hoffmann La Roche | Verfahren zur herstellung von optisch aktiven alpha-hydroxycarbonsaeuren. |
DK269987A (da) * | 1986-06-03 | 1987-12-04 | Hoffmann La Roche | Enzym og fremgangsmaade til fremstilling deraf |
US4876200A (en) * | 1986-07-08 | 1989-10-24 | Shell Oil Company | New strains of pseudomonas putida |
-
1989
- 1989-05-12 GB GB898910958A patent/GB8910958D0/en active Pending
-
1990
- 1990-05-11 AU AU56478/90A patent/AU643687B2/en not_active Ceased
- 1990-05-11 JP JP2507403A patent/JP3045540B2/ja not_active Expired - Fee Related
- 1990-05-11 CA CA002055442A patent/CA2055442C/fr not_active Expired - Lifetime
- 1990-05-11 WO PCT/GB1990/000727 patent/WO1990013634A2/fr active IP Right Grant
- 1990-05-11 HU HU904408A patent/HUT59959A/hu unknown
- 1990-05-11 DE DE69021564T patent/DE69021564T2/de not_active Expired - Fee Related
- 1990-05-11 US US07/784,445 patent/US5298414A/en not_active Expired - Fee Related
- 1990-05-11 EP EP90907336A patent/EP0471740B1/fr not_active Expired - Lifetime
- 1990-05-11 GB GB9010561A patent/GB2231332B/en not_active Expired - Fee Related
-
1994
- 1994-01-19 US US08/183,307 patent/US5387515A/en not_active Expired - Lifetime
Non-Patent Citations (7)
Title |
---|
Chemical Abstracts, vol. 100, no. 3, 16 January 1984, (Columbus, Ohio, US), R. Ammon et al.: "Determining heroin esterase in serum", see page 4 * |
Chemical Abstracts, vol. 110, no. 5, 30 January 1989, (Columbus, Ohio, US), F. Crespi et al.: "Cerebral "heroin esterases": a component of the pharmacological activity of heroin?", see page 8 * |
Chemical Abstracts, vol. 84, no. 5, 2 February 1976, (Columbus, Ohio, US), P. Liras et al.: "Enzymic transformation of morphine by hydrozysteroid dehydrogenase from pseudomonas testosteroni", see page 167 * |
Chemical Abstracts, vol. 85, no. 3, 19 July 1976, (Columbus, Ohio, US), D.A. Smith et al.: "Identification of an arylesterase as the enzyme hydrolyzing diacetylmorphine (heroin) in human plasma", see page 8 * |
Chemical Abstracts, vol. 89, no. 3, 17 July 1978, (Columbus, Ohio, US), V. Jhaveri: "Purification of morphine transforming enzyme from pseudomonas testoseroni", see page 236 * |
Chemical Abstracts, vol. 99, no. 19, 7 November 1983, (Columbus, Ohio, US), J.A. Owen et al.: "Diacetylmorphine (heroin) hydrolases in human blood", see page 15 * |
See also references of EP0471740A1 * |
Also Published As
Publication number | Publication date |
---|---|
EP0471740B1 (fr) | 1995-08-09 |
HU904408D0 (en) | 1992-01-28 |
CA2055442C (fr) | 1999-06-15 |
GB8910958D0 (en) | 1989-06-28 |
EP0471740A1 (fr) | 1992-02-26 |
DE69021564T2 (de) | 1996-01-18 |
GB9010561D0 (en) | 1990-07-04 |
AU5647890A (en) | 1990-11-29 |
JP3045540B2 (ja) | 2000-05-29 |
US5298414A (en) | 1994-03-29 |
GB2231332A (en) | 1990-11-14 |
HUT59959A (en) | 1992-07-28 |
GB2231332B (en) | 1993-04-21 |
CA2055442A1 (fr) | 1990-11-13 |
US5387515A (en) | 1995-02-07 |
DE69021564D1 (de) | 1995-09-14 |
JPH05504252A (ja) | 1993-07-08 |
WO1990013634A2 (fr) | 1990-11-15 |
AU643687B2 (en) | 1993-11-25 |
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