WO1990012568A1 - Device for controlled dosed feeding of active substances into an operative medium - Google Patents
Device for controlled dosed feeding of active substances into an operative medium Download PDFInfo
- Publication number
- WO1990012568A1 WO1990012568A1 PCT/SU1989/000109 SU8900109W WO9012568A1 WO 1990012568 A1 WO1990012568 A1 WO 1990012568A1 SU 8900109 W SU8900109 W SU 8900109W WO 9012568 A1 WO9012568 A1 WO 9012568A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cylindrical
- environment
- κορπusa
- active substances
- devices
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0068—Rumen, e.g. rumen bolus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/1407—Infusion of two or more substances
- A61M5/1409—Infusion of two or more substances in series, e.g. first substance passing through container holding second substance, e.g. reconstitution systems
Definitions
- a pill with a net spray ( ⁇ , ⁇ , 4326522), consisting of cylindrical capsules made from a biologically acceptable substance that is free from mixed substances. Cylindrical capsules are scattered 25 between the flexible, elastic elements of the body, which cause the ingestion of lively food to eat, which can lead to the loss of life-threatening food.
- a net spray ⁇ , ⁇ , 4326522
- Cylindrical capsules are scattered 25 between the flexible, elastic elements of the body, which cause the ingestion of lively food to eat, which can lead to the loss of life-threatening food.
- the ruminant 40 live interface is located along with the front of the unit, and inside - 2 - the stomach, due to the total flexibility, is subject to angle that is in the range of 75 up to 90 ° to the extent of the integral. This ensures that the device is kept in the mouth of the stomach for the entire period of its functioning.
- the housing is located on the ground floor, which is secured to the one side of the dining room and is open to the other side.
- stomach fluid for communication with a medium function.
- an active substance is discharged from the body through a direct connection with the body. This device does not allow the administration of small, immiscible, active substances.
- this device can cause damage to the stomach wall due to the large number of flexible devices located on an external device.
- the task posed is solved by the fact that in the device for the commercially available input of active substances in the environment
- a connector is located that separates the cylindrical housing into parts, which are sealed from the hostile environment.
- Each of the parts of the cylinder has a different body, there is at least one medium for the connection of the body with a medium function.
- garbage courses are connected between each other's teachings, - 3 - ⁇ s ⁇ y ⁇ e ⁇ endi ⁇ ulya ⁇ na ⁇ d ⁇ ln ⁇ y ⁇ si tsilind ⁇ iches ⁇ g ⁇ ⁇ usa and ⁇ aya us ⁇ an ⁇ vlena with v ⁇ zm ⁇ zhn ⁇ s ⁇ yu ⁇ azv ⁇ a chas- ⁇ ey tsilind ⁇ iches ⁇ g ⁇ ⁇ usa in m ⁇ men ⁇ ⁇ mescheniya tsilind ⁇ iches ⁇ g ⁇ ⁇ usa in s ⁇ edu ⁇ un ⁇ tsi ⁇ ni ⁇ vaniya ⁇ dn ⁇ y ⁇ n ⁇ si ⁇ eln ⁇ 5 d ⁇ ug ⁇ y in ⁇ l ⁇ s ⁇ s ⁇ i, ⁇ a ⁇ alleln ⁇ y ⁇ d ⁇ ln ⁇ y ⁇ si tsilind ⁇ iches ⁇ g ⁇ ⁇ usa.
- Tseles ⁇ b ⁇ azn ⁇ ch ⁇ by us ⁇ ys ⁇ v ⁇ byl ⁇ snabzhen ⁇ ⁇ men- necks me ⁇ e ⁇ dnim ⁇ i ⁇ sa ⁇ m of ⁇ as ⁇ v ⁇ im ⁇ g ⁇ ma ⁇ e ⁇ iala, ⁇ azme- schennym on the outer ⁇ ve ⁇ n ⁇ s ⁇ i tsilind ⁇ iches ⁇ g ⁇ ⁇ usa and 10 ude ⁇ zhivaschim chas ⁇ i tsilind ⁇ iches ⁇ g ⁇ ⁇ usa in s ⁇ b ⁇ ann ⁇ m s ⁇ s ⁇ yanii d ⁇ m ⁇ men ⁇ a ⁇ mescheniya tsilind ⁇ iches ⁇ g ⁇ ⁇ usa in s ⁇ edu ⁇ un ⁇ tsi ⁇ ni ⁇ vaniya.
- the parts of the cylindrical body be divided into a corner that is in the range of 10 to 15 90 °.
- the home appliance is located in the area, the front end is simple with a cylindrical housing.
- the product is located in the flat area, at a 25-sided, integral, cylindrical outlet.
- the cylindrical housing is removable with a one-piece connector and the adapter is two-part cylindrical, and it is 90 ° apart. 30 It is advisable that the cylindrical housing is made with a two-piece connector and a cutting adapter is divided by a half, and it is 60 ° apart.
- cylindrical housing is 35 and is removable with the housing that allows for separation of the cylindrical part and the
- This device for the use of it for the treatment and the enjoyment of civils makes it possible to increase the weight gain for two times a day.
- Fig. 2 is a device for the sale of active substances, otherwise it may be disposed of.
- Fig. 3 depicts a general view of the device for the commercially available use of active materials in the event of an overstatement of the device;
- Fig. 4 depicts devices for the commercially available input of active substances, which is transverse to the cut-off line KU-KU in Fig. 3;
- Fig. 5 depicts a general view of the device for the commercially available input of active substances in a working environment.
- Fig. 6 depicts a general view of the device of the other party to the commercially available input of active broadcasts into the assembled system.
- FIG. 7 depicts a general view of the device for the commercially available input of active substances in the case of an output of an atherosclerosis
- Fig. 8 depicts a general view of the device for the commercially available input of active substances, apart from the fact that they are free to use, apart from the
- Part 3 of body I contains active substance 7 in the form of a compilation with a suitable matrix 8 or in its pure form. 3 every part of 3 cases I have either one and the same active substance 7, or more, for example, in the other 3 ⁇ -
- an anthelmintic drug-tyvidine is placed, and in another part 3 an antibiotic is placed - a vetterin.
- U I have a functional environment.
- ⁇ ⁇ ab ⁇ chem s ⁇ s ⁇ yanii us ⁇ ys ⁇ v ⁇ for ⁇ n ⁇ li ⁇ uem ⁇ g ⁇ d ⁇ zi ⁇ vann ⁇ g ⁇ vv ⁇ - yes a ⁇ ivny ⁇ vesches ⁇ v ⁇ e ⁇ b ⁇ e ⁇ ae ⁇ ⁇ a ⁇ uyu ⁇ mu, ⁇ aya ⁇ bes- ⁇ echivae ⁇ ude ⁇ zhanie ⁇ ns ⁇ u ⁇ tsii in zhelud ⁇ e zhiv ⁇ ny ⁇ , ⁇ ichem chas ⁇ i 3 ( ⁇ ig.Z) ⁇ usa I ⁇ ien ⁇ i ⁇ vany ⁇ n ⁇ si ⁇ eln ⁇ d ⁇ ug
- Part 3 of building I has been supplied with a total of 9, which by dividing the internal volume of each part of 3 building I by part 10. This allows you to enter an active
- Part 1 in addition to 10 part 3, is inactive - only 7 are available.
- Page 10 of your friend and friend. Box 9 is reserved for the internal walls of Part 3 and placed in
- the size of the device is intended for the introduction into the stomach of animals that are limited in size of the esophagus. An optimal number of 3 parts of I is exactly four. If the device will enter the stomach
- Part 3 of the Part 3 - 8 - sa I desirably have a corner in the range of 10 to 90 °. At an angle of 10 °, there is no need to hold the device, for example, in the stomach, it is lively for the entire time that the active substances 7 enter the environment.
- ⁇ - IU ⁇ g ⁇ not ⁇ bes ⁇ echivav ⁇ sya ude ⁇ zhaniv us ⁇ ys ⁇ va, na ⁇ ime ⁇ in zhelud ⁇ e zhiv ⁇ n ⁇ g ⁇ , all v ⁇ emya vv ⁇ da a ⁇ ivny ⁇ vesches ⁇ v 7
- Actual material 7 may be housed inside the compartment I and without the primary matrix 8, but in the form of a bulk, compressed or fused mass.
- part 3 (fig. ⁇ ) of the chamber I is connected to the other
- a complete version of the housing I is plug-in with parts 3, which are unbundled in one of the other areas, in addition to a large external drive,
- the device In the event that the device is disposed of in an environment where liquid from the medium through the operation of 6 is empty, it is disposed of in the case of a medium of 7, which is housed in a medium of 8.
- part 3 of each part 3 is included in the medium of activity four: tividine, the pain.
- 20 ⁇ case ⁇ gda ⁇ dna Part 3 ( ⁇ ig.8) ⁇ azdelena ⁇ e ⁇ eg ⁇ d ⁇ y 9 two ⁇ se ⁇ a 10, and Part 3 d ⁇ ugaya ⁇ azdelena ⁇ e ⁇ eg ⁇ d ⁇ y 9 ⁇ i ⁇ se ⁇ a 10 us ⁇ ys ⁇ v ⁇ ⁇ zv ⁇ lyae ⁇ d ⁇ - zi ⁇ vash ⁇ vv ⁇ di ⁇ ⁇ dn ⁇ v ⁇ emenn ⁇ ⁇ ya ⁇ a ⁇ ivny ⁇ vesches ⁇ v 7: vi ⁇ a ⁇ e ⁇ in, ⁇ l ⁇ id na ⁇ iya , zinc sulfate, tyvidine, glucose 25.
- Deliberate use of the drug can be used as a therapeutic antihelmintic device for the treatment of and is free of vegetative fatigue.
- the invention may be used in medicine, in general, and in medical thought.
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/SU1989/000109 WO1990012568A1 (en) | 1989-04-21 | 1989-04-21 | Device for controlled dosed feeding of active substances into an operative medium |
EP19890909905 EP0425672A4 (en) | 1989-04-21 | 1989-04-21 | Device for controlled dosed feeding of active substances into an operative medium |
FI906329A FI906329A0 (fi) | 1989-04-21 | 1990-12-20 | Anordning foer kontrollerad uppmaett frigoering av aktiva substanser i ett funktionellt medium. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/SU1989/000109 WO1990012568A1 (en) | 1989-04-21 | 1989-04-21 | Device for controlled dosed feeding of active substances into an operative medium |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1990012568A1 true WO1990012568A1 (en) | 1990-11-01 |
Family
ID=21617455
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/SU1989/000109 WO1990012568A1 (en) | 1989-04-21 | 1989-04-21 | Device for controlled dosed feeding of active substances into an operative medium |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0425672A4 (ru) |
FI (1) | FI906329A0 (ru) |
WO (1) | WO1990012568A1 (ru) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3732865A (en) * | 1971-01-13 | 1973-05-15 | Alza Corp | Osmotic dispenser |
US4416659A (en) * | 1981-11-09 | 1983-11-22 | Eli Lilly And Company | Sustained release capsule for ruminants |
US4608048A (en) * | 1984-12-06 | 1986-08-26 | Alza Corporation | Dispensing device with drug delivery patterns |
US4612008A (en) * | 1983-05-11 | 1986-09-16 | Alza Corporation | Osmotic device with dual thermodynamic activity |
SU1484280A3 (ru) * | 1984-05-31 | 1989-05-30 | Эли Лилли Энд Компани (Фирма) | Устройство длительного действи дл выделени лекарственного препарата в рубец жвачных животных |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU588828B2 (en) * | 1984-09-14 | 1989-09-28 | Commonwealth Scientific And Industrial Research Organisation | Controlled release capsule |
DE3680024D1 (de) * | 1985-05-10 | 1991-08-08 | Merck & Co Inc | Abgabesystem fuer arzneimittel, das waehrend einer kontrollierten zeitspanne im magen zurueckgehalten werden kann. |
AU591297B2 (en) * | 1986-07-15 | 1989-11-30 | Pitman-Moore Australia Limited | Intra-ruminal depot |
-
1989
- 1989-04-21 EP EP19890909905 patent/EP0425672A4/de not_active Withdrawn
- 1989-04-21 WO PCT/SU1989/000109 patent/WO1990012568A1/ru not_active Application Discontinuation
-
1990
- 1990-12-20 FI FI906329A patent/FI906329A0/fi not_active IP Right Cessation
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3732865A (en) * | 1971-01-13 | 1973-05-15 | Alza Corp | Osmotic dispenser |
US4416659A (en) * | 1981-11-09 | 1983-11-22 | Eli Lilly And Company | Sustained release capsule for ruminants |
US4612008A (en) * | 1983-05-11 | 1986-09-16 | Alza Corporation | Osmotic device with dual thermodynamic activity |
SU1484280A3 (ru) * | 1984-05-31 | 1989-05-30 | Эли Лилли Энд Компани (Фирма) | Устройство длительного действи дл выделени лекарственного препарата в рубец жвачных животных |
US4608048A (en) * | 1984-12-06 | 1986-08-26 | Alza Corporation | Dispensing device with drug delivery patterns |
Non-Patent Citations (1)
Title |
---|
See also references of EP0425672A4 * |
Also Published As
Publication number | Publication date |
---|---|
EP0425672A4 (en) | 1991-10-16 |
EP0425672A1 (de) | 1991-05-08 |
FI906329A0 (fi) | 1990-12-20 |
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