WO1990012488A3 - Clone d'un virus arn a double brin applique a la production d'anticorps, etude du changement de structure semblable au retrovirus et production de proteines dans la levure - Google Patents
Clone d'un virus arn a double brin applique a la production d'anticorps, etude du changement de structure semblable au retrovirus et production de proteines dans la levure Download PDFInfo
- Publication number
- WO1990012488A3 WO1990012488A3 PCT/US1990/001717 US9001717W WO9012488A3 WO 1990012488 A3 WO1990012488 A3 WO 1990012488A3 US 9001717 W US9001717 W US 9001717W WO 9012488 A3 WO9012488 A3 WO 9012488A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- frameshifting
- production
- yeast
- double
- stranded rna
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/00022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Une molécule d'ADN de recombinaison est utile pour déterminer l'effet d'un agent sur le changement de structure translationnelle qui est dirigé par une séquence de nucléotides viraux comme moyen de régulation de l'expression de gènes viraux. Cette molécule d'ADN comprend un gène indicateur pour la détection du changement de structure pendant la translation et un segment ADN qui code la partie du génome ARN à double brin du virus L-A de la levure qui guide ou dirige le changement de structure de translation entre la structure de lecture pour la protéine de revêtement principal et la structure de lecture pour la polymérase ARN.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31121789A | 1989-04-05 | 1989-04-05 | |
US311,217 | 1989-04-05 | ||
US49236490A | 1990-03-09 | 1990-03-09 | |
US492,364 | 1990-03-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1990012488A2 WO1990012488A2 (fr) | 1990-11-01 |
WO1990012488A3 true WO1990012488A3 (fr) | 1990-11-29 |
Family
ID=26977785
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1990/001717 WO1990012488A2 (fr) | 1989-04-05 | 1990-04-04 | Clone d'un virus arn a double brin applique a la production d'anticorps, etude du changement de structure semblable au retrovirus et production de proteines dans la levure |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU5630590A (fr) |
WO (1) | WO1990012488A2 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9102939B2 (en) | 1997-12-23 | 2015-08-11 | The Carnegie Institution Of Washington | Genetic inhibition by double-stranded RNA |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ547283A (en) | 1998-03-20 | 2008-06-30 | Commw Scient Ind Res Org | Control of gene expression |
AUPP249298A0 (en) | 1998-03-20 | 1998-04-23 | Ag-Gene Australia Limited | Synthetic genes and genetic constructs comprising same I |
EP1147204A1 (fr) | 1999-01-28 | 2001-10-24 | Medical College Of Georgia Research Institute, Inc. | Composition et methode destinees a l'attenuation in vivo et in vitro de l'expression genique utilisant de l'arn double brin |
US6423885B1 (en) | 1999-08-13 | 2002-07-23 | Commonwealth Scientific And Industrial Research Organization (Csiro) | Methods for obtaining modified phenotypes in plant cells |
EP1229134A3 (fr) | 2001-01-31 | 2004-01-28 | Nucleonics, Inc | Utilisation de l'inhibition post-transcriptionnelle pour l'identification des séquences d'acides nucléiques qui modifient la fonction d'une cellule |
-
1990
- 1990-04-04 AU AU56305/90A patent/AU5630590A/en not_active Abandoned
- 1990-04-04 WO PCT/US1990/001717 patent/WO1990012488A2/fr unknown
Non-Patent Citations (9)
Title |
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CELL, Volume 35, issued December 1983, J.T. LIS et al.: "New heat shock puffs and beta-galactosidase activity resulting from transformation of drosophila with an hsp70-lacZ hybrid gene", pages 403-410. See entire article. * |
CELL, Volume 55, issued 18 November 1988, T. FUJIMURA et al.: "Gene overlap results in a viral protein having an RNA binding domain and a major coat protein domain", pp. 663-671. See entire article. * |
CELL, Volume 55, issued 23 December 1988, W. WILSON et al.: "HIV Expression Strategies Ribosomal frameshifting is directed by a short sequence in both mammalian and yeast systems", pp. 1159-1169. See entire document. * |
GenBank and UEMBL nucleotide sequence data bases. Sequence provided to GenBank data base on 08 September 1988 by R.B. WICKNER. (93% sequence homology with nucleotides 4041 to 4500 of the instant application). * |
J. BIOL. CHEM., Volume 264, No. 12, issued 25 April 1989, T. ICHO et al.: "The double-stranded RNA genome of yeast virus encodes its own putative RNA polymerase by fusing two open reading frames", pp. 6716-6723. See the entire document. * |
MOL. CELL. BIOL., Volume 4, Number 1, issued January 1984, D.J. THIELE et al.: "Multiple L double-stranded RNA species of Saccharomyces cerevisiae: evidence for separate encapsidation", pp. 92-100. See entire article. * |
NUCL. ACID. RES., Volume 13, Nunber 5, issued April 1985, J. BRUENN et al.: "Long internal inverted repeat in a yeast double-stranded RNA", pp. 1575-1591. See entire document. * |
PROC. NATL. ACAD. SCI. USA, Volume 85, issued June 1988, R. ESTEBAN et al.: "Site-specific binding of viral plus single-stranded RNA to replicase-containing open virus-like particles of yeast", pages 4411-4415. See entire article. * |
YEAST, Volume 4, special issue, issued 07 August 1988, W. WILSON et al.: "Human Immunodeficiency virus (HIV-1) gene expression: ribosomal frameshifting requires a short sequence and no secondary structure in yeast and mammalian systems", pp. S177. See the entire abstract. * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9102939B2 (en) | 1997-12-23 | 2015-08-11 | The Carnegie Institution Of Washington | Genetic inhibition by double-stranded RNA |
Also Published As
Publication number | Publication date |
---|---|
AU5630590A (en) | 1990-11-16 |
WO1990012488A2 (fr) | 1990-11-01 |
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