WO1990005540A1 - Anticorps monoclonaux specifiques d'antigenes tumoraux - Google Patents

Anticorps monoclonaux specifiques d'antigenes tumoraux Download PDF

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Publication number
WO1990005540A1
WO1990005540A1 PCT/US1989/005208 US8905208W WO9005540A1 WO 1990005540 A1 WO1990005540 A1 WO 1990005540A1 US 8905208 W US8905208 W US 8905208W WO 9005540 A1 WO9005540 A1 WO 9005540A1
Authority
WO
WIPO (PCT)
Prior art keywords
monoclonal antibody
hybridoma
cells
membrane component
tumor
Prior art date
Application number
PCT/US1989/005208
Other languages
English (en)
Inventor
Lee A. Henderson
Original Assignee
Administrators Of The Tulane Educational Fund
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Administrators Of The Tulane Educational Fund filed Critical Administrators Of The Tulane Educational Fund
Publication of WO1990005540A1 publication Critical patent/WO1990005540A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Anticorps moncoclonaux spécifiques de certaines tumeurs, reconnaissant les déterminants antigéniques d'un composant de membrane caractéristique du carcinoma spinocellulaire, et hybridome produisant ces anticorps. L'invention se rapporte également à un kit de diagnostic comprenant les anticorps spécifiques de certaines tumeurs, ainsi qu'à l'utilisation de ces anticorps pour déterminer la présence de cellules affectées par le carcinome spinocellulaire dans un échantillon biologique.
PCT/US1989/005208 1988-11-23 1989-11-22 Anticorps monoclonaux specifiques d'antigenes tumoraux WO1990005540A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27552688A 1988-11-23 1988-11-23
US275,526 1988-11-23

Publications (1)

Publication Number Publication Date
WO1990005540A1 true WO1990005540A1 (fr) 1990-05-31

Family

ID=23052688

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1989/005208 WO1990005540A1 (fr) 1988-11-23 1989-11-22 Anticorps monoclonaux specifiques d'antigenes tumoraux

Country Status (2)

Country Link
AU (1) AU4668889A (fr)
WO (1) WO1990005540A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5545532A (en) * 1993-02-05 1996-08-13 Epigen, Inc. Human carcinoma antigen (HCA), HCA antibodies, HCA immunoassays and methods of imaging
WO2004024767A1 (fr) * 2002-09-10 2004-03-25 Canag Diagnostics Ab Immuno-essais servant a effectuer la determination specifique d'isoformes de scca
EP1487877A2 (fr) * 2001-09-18 2004-12-22 Genentech, Inc. Compositions et procedes pour le diagnostic et le traitement des tumeurs

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4569788A (en) * 1983-05-18 1986-02-11 The United States Of America As Represented By The Department Of Health And Human Services Monoclonal antibodies against non small cell lung cancer
US4708862A (en) * 1983-02-22 1987-11-24 Xoma Corporation Radioimmuno detection of human cancers using anti-tumor monoclonal antibody

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708862A (en) * 1983-02-22 1987-11-24 Xoma Corporation Radioimmuno detection of human cancers using anti-tumor monoclonal antibody
US4569788A (en) * 1983-05-18 1986-02-11 The United States Of America As Represented By The Department Of Health And Human Services Monoclonal antibodies against non small cell lung cancer

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CANCER RESEARCH, Vol. 46, issued July 1986 (USA), KIMMEL et al.: "Altered Expression in Squamous Carcinoma Cells of an Orientation Restricted Epithelial Antigen Detected by Monoclonal Antibody A9", see pages 3614 to 3623. *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5545532A (en) * 1993-02-05 1996-08-13 Epigen, Inc. Human carcinoma antigen (HCA), HCA antibodies, HCA immunoassays and methods of imaging
US5693763A (en) * 1993-02-05 1997-12-02 Epigen, Inc. Antibodies to human carcinoma antigen
US5808005A (en) * 1993-02-05 1998-09-15 Epigen, Inc. Human carcinoma antigen
EP1487877A2 (fr) * 2001-09-18 2004-12-22 Genentech, Inc. Compositions et procedes pour le diagnostic et le traitement des tumeurs
EP1487877A4 (fr) * 2001-09-18 2005-08-24 Genentech Inc Compositions et procedes pour le diagnostic et le traitement des tumeurs
JP2009149604A (ja) * 2001-09-18 2009-07-09 Genentech Inc 腫瘍の診断及び治療のための組成物と方法
KR101008758B1 (ko) * 2001-09-18 2011-01-14 제넨테크, 인크. 종양의 진단 및 치료를 위한 방법 및 이를 위한 조성물
US7939268B2 (en) 2001-09-18 2011-05-10 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US7951546B2 (en) 2001-09-18 2011-05-31 Genetech, Inc. Compositions and methods for the diagnosis and treatment of tumor
WO2004024767A1 (fr) * 2002-09-10 2004-03-25 Canag Diagnostics Ab Immuno-essais servant a effectuer la determination specifique d'isoformes de scca

Also Published As

Publication number Publication date
AU4668889A (en) 1990-06-12

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