WO1989007656A3 - Essais et controles cliniques, compositions pharmaceutiques de traitement de maladies autoimmunitaires - Google Patents
Essais et controles cliniques, compositions pharmaceutiques de traitement de maladies autoimmunitaires Download PDFInfo
- Publication number
- WO1989007656A3 WO1989007656A3 PCT/GB1989/000140 GB8900140W WO8907656A3 WO 1989007656 A3 WO1989007656 A3 WO 1989007656A3 GB 8900140 W GB8900140 W GB 8900140W WO 8907656 A3 WO8907656 A3 WO 8907656A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- treatment
- auto
- immune diseases
- disclosed
- monitoring
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
- C12Q2334/70—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases the product, e.g. phenol, naphthol being diazotised in situ, e.g. with Fast Red
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
On a découvert que l'activité de l'estérase de la sérine est impliquée dans un grand nombre d'états cliniques. Un test rapide de dépistage de l'activité de l'estérase de la sérine comprend a) la fixation de l'échantillon à examiner, par exemple dans de la formaline; et b) la mise en contact de l'échantillon fixé avec une solution contenant de l'ester de N-alpha benzyloxycarbonyl-L-lysinethiobenzyle et un chromogène (par exemple Bleu Rapide BB). Ce test sert d'indicateur de diagnostic ou de contrôle de l'évolution d'un traitement thérapeutique. Techniques de traitement de maladies, en particulier de maladies autoimmunitaires.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888803109A GB8803109D0 (en) | 1988-02-11 | 1988-02-11 | Improvements in/relating to clinical testing monitoring & pharmaceutical compositions for treatment of auto-immune diseases |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1989007656A2 WO1989007656A2 (fr) | 1989-08-24 |
WO1989007656A3 true WO1989007656A3 (fr) | 1989-09-21 |
Family
ID=10631489
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB1989/000140 WO1989007656A2 (fr) | 1988-02-11 | 1989-02-13 | Essais et controles cliniques, compositions pharmaceutiques de traitement de maladies autoimmunitaires |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0330358A3 (fr) |
JP (1) | JPH02503058A (fr) |
AU (1) | AU3065789A (fr) |
GB (1) | GB8803109D0 (fr) |
WO (1) | WO1989007656A2 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69028126T2 (de) * | 1989-01-30 | 1997-01-23 | Loesche Walter J | Festephasentest zum Nachweis der periodentalen Krankheit in einem subgingivalem Fleck |
US10539487B2 (en) | 2010-03-04 | 2020-01-21 | Ventana Medical Systems, Inc. | Systems and methods for monitoring tissue sample processing |
CA2788664C (fr) | 2010-03-04 | 2023-04-11 | Ventana Medical Systems, Inc. | Systeme de traitement pour traiter des echantillons a l'aide d'energie acoustique |
US10126216B2 (en) | 2011-02-17 | 2018-11-13 | Ventana Medical Systems, Inc. | Method for tissue sample fixation |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4166825A (en) * | 1978-08-17 | 1979-09-04 | Abbott Laboratories | Chromogenic substrates |
FR2531453A1 (fr) * | 1982-08-03 | 1984-02-10 | Torii & Co Ltd | Procede pour determiner l'activite des enzymes |
EP0157362A2 (fr) * | 1984-04-06 | 1985-10-09 | Miles Inc. | Esters chromogènes d'aminoacides et peptides, procédé pour leur préparation, utilisation de ces composés pour procédés analytiques ainsi comme agents pour marquer enzymes estérolytiques et/ou protéolytiques |
EP0185335A2 (fr) * | 1984-12-21 | 1986-06-25 | Roche Diagnostics GmbH | Procédé pour la détermination d'une allergie et pour la détermination spécifique d'allergène responsable de l'allergie |
EP0254000A1 (fr) * | 1986-06-16 | 1988-01-27 | Miles Inc. | Détection rapide de N-gonorrhée sans culture |
-
1988
- 1988-02-11 GB GB888803109A patent/GB8803109D0/en active Pending
-
1989
- 1989-02-13 EP EP89301357A patent/EP0330358A3/fr not_active Withdrawn
- 1989-02-13 AU AU30657/89A patent/AU3065789A/en not_active Abandoned
- 1989-02-13 JP JP1502349A patent/JPH02503058A/ja active Pending
- 1989-02-13 WO PCT/GB1989/000140 patent/WO1989007656A2/fr unknown
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4166825A (en) * | 1978-08-17 | 1979-09-04 | Abbott Laboratories | Chromogenic substrates |
FR2531453A1 (fr) * | 1982-08-03 | 1984-02-10 | Torii & Co Ltd | Procede pour determiner l'activite des enzymes |
EP0157362A2 (fr) * | 1984-04-06 | 1985-10-09 | Miles Inc. | Esters chromogènes d'aminoacides et peptides, procédé pour leur préparation, utilisation de ces composés pour procédés analytiques ainsi comme agents pour marquer enzymes estérolytiques et/ou protéolytiques |
EP0185335A2 (fr) * | 1984-12-21 | 1986-06-25 | Roche Diagnostics GmbH | Procédé pour la détermination d'une allergie et pour la détermination spécifique d'allergène responsable de l'allergie |
EP0254000A1 (fr) * | 1986-06-16 | 1988-01-27 | Miles Inc. | Détection rapide de N-gonorrhée sans culture |
Also Published As
Publication number | Publication date |
---|---|
GB8803109D0 (en) | 1988-03-09 |
AU3065789A (en) | 1989-09-06 |
EP0330358A2 (fr) | 1989-08-30 |
WO1989007656A2 (fr) | 1989-08-24 |
EP0330358A3 (fr) | 1989-12-06 |
JPH02503058A (ja) | 1990-09-27 |
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