WO1988007368A3 - Composition medicamenteuse pour le traitement et la prevention de maladies dues a une cytotoxicite a mediation cellulaire, renfermant au moins un derive de la pyridine comme principe actif - Google Patents

Composition medicamenteuse pour le traitement et la prevention de maladies dues a une cytotoxicite a mediation cellulaire, renfermant au moins un derive de la pyridine comme principe actif Download PDF

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Publication number
WO1988007368A3
WO1988007368A3 PCT/FR1988/000158 FR8800158W WO8807368A3 WO 1988007368 A3 WO1988007368 A3 WO 1988007368A3 FR 8800158 W FR8800158 W FR 8800158W WO 8807368 A3 WO8807368 A3 WO 8807368A3
Authority
WO
WIPO (PCT)
Prior art keywords
treating
active principle
incorporating
preventing diseases
cytotoxicity
Prior art date
Application number
PCT/FR1988/000158
Other languages
English (en)
Other versions
WO1988007368A2 (fr
Inventor
Laurent Degos
Gerard Tobelem
Original Assignee
Laurent Degos
Gerard Tobelem
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laurent Degos, Gerard Tobelem, Inst Nat Sante Rech Med filed Critical Laurent Degos
Publication of WO1988007368A2 publication Critical patent/WO1988007368A2/fr
Publication of WO1988007368A3 publication Critical patent/WO1988007368A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Cette composition renferme, à titre de principe actif, au moins un composé choisi parmi les dérivés de thiéno-pyridine représentés par la formule générale (I); elle est destinée au traitement et à la prévention de maladies autoimmunes, y compris les maladies rhumatismales, des rejets de greffes allogéniques et de la maladie du greffon contre l'hôte, ainsi que des cytolyses après infection par les micro-organismes. X = O ou S; R1 = H; alkyle; alcoxy; phényle ou benzyle éventuellement substitué; alpha-naphtyle ou thiényle; R2 = H, Hal., hydroxy, alkyle ou alcoxy, nitro, amino, phényle ou alcoxycarbonyle; n = 0 ou un nombre entier allant de 1 à 15; R3, R4 = H, Hal., alkyle, nitro, amino.
PCT/FR1988/000158 1987-03-26 1988-03-25 Composition medicamenteuse pour le traitement et la prevention de maladies dues a une cytotoxicite a mediation cellulaire, renfermant au moins un derive de la pyridine comme principe actif WO1988007368A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR87/04241 1987-03-26
FR8704241A FR2612777A1 (fr) 1987-03-26 1987-03-26 Composition medicamenteuse pour le traitement et la prevention de maladies dues a une cytotoxicite a mediation cellulaire, renfermant au moins un derive de la pyridine comme principe actif

Publications (2)

Publication Number Publication Date
WO1988007368A2 WO1988007368A2 (fr) 1988-10-06
WO1988007368A3 true WO1988007368A3 (fr) 1988-11-03

Family

ID=9349464

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1988/000158 WO1988007368A2 (fr) 1987-03-26 1988-03-25 Composition medicamenteuse pour le traitement et la prevention de maladies dues a une cytotoxicite a mediation cellulaire, renfermant au moins un derive de la pyridine comme principe actif

Country Status (3)

Country Link
AU (1) AU1575688A (fr)
FR (1) FR2612777A1 (fr)
WO (1) WO1988007368A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL81352A (en) * 1986-01-27 1990-11-05 Colgate Palmolive Co Detergent softener compositions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2012161A (en) * 1978-01-06 1979-07-25 Sopharma Sa Anti-cancer and cancer metastasis preventing agent
FR2461496A2 (fr) * 1979-07-17 1981-02-06 Sanofi Sa Derives pyridiniques et leur application therapeutique

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2336932A2 (fr) * 1973-02-01 1977-07-29 Centre Etd Ind Pharma Derives pyridiniques, leur preparation et leurs applications
FR2345150A2 (fr) * 1975-08-06 1977-10-21 Centre Etd Ind Pharma Nouveaux derives de la thienopyridine, et leur application
FR2215948B1 (fr) * 1973-02-01 1976-05-14 Centre Etd Ind Pharma
IT8222600A0 (it) * 1982-07-28 1982-07-28 Pietro Tommaso Tessitore Nuovi idrossibenzensolfonati della 5-(o-clorobenzil)-4,5,6,7-tetraidro tieno parentesi quadra aperta 3,2-c parentesi quadra chiusa piridina.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2012161A (en) * 1978-01-06 1979-07-25 Sopharma Sa Anti-cancer and cancer metastasis preventing agent
FR2461496A2 (fr) * 1979-07-17 1981-02-06 Sanofi Sa Derives pyridiniques et leur application therapeutique

Also Published As

Publication number Publication date
FR2612777A1 (fr) 1988-09-30
WO1988007368A2 (fr) 1988-10-06
AU1575688A (en) 1988-11-02

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