WO1986007537A3 - Compositions pharmaceutiques contenant des azanaphtalenes - Google Patents

Compositions pharmaceutiques contenant des azanaphtalenes

Info

Publication number
WO1986007537A3
WO1986007537A3 PCT/US1986/001298 US8601298W WO8607537A3 WO 1986007537 A3 WO1986007537 A3 WO 1986007537A3 US 8601298 W US8601298 W US 8601298W WO 8607537 A3 WO8607537 A3 WO 8607537A3
Authority
WO
WIPO (PCT)
Prior art keywords
azanaphthalenes
pharmaceutical compositions
compositions containing
formula
azanaphtalenes
Prior art date
Application number
PCT/US1986/001298
Other languages
English (en)
Other versions
WO1986007537A2 (fr
Inventor
Sidney Randall Smith
Marvin Ira Siegel
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/808,404 external-priority patent/US4945095A/en
Priority claimed from US06/839,308 external-priority patent/US4666922A/en
Priority claimed from US06/871,691 external-priority patent/US4801589A/en
Application filed by Schering Corp filed Critical Schering Corp
Priority to AT86904018T priority Critical patent/ATE51150T1/de
Priority to DE8686904018T priority patent/DE3669656D1/de
Priority to JP61503480A priority patent/JPH0676322B2/ja
Publication of WO1986007537A2 publication Critical patent/WO1986007537A2/fr
Publication of WO1986007537A3 publication Critical patent/WO1986007537A3/fr
Priority to SG925/92A priority patent/SG92592G/en
Priority to HK93592A priority patent/HK93592A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Utilisation d'azanaphtalènes pour préparer des médicaments permettant de supprimer la réaction du système immunitaire. Ces azanaphtalènes ont la formule Ia, Ib ou Ic où Ac a la formule A'c ou A''c.
PCT/US1986/001298 1985-06-18 1986-06-18 Compositions pharmaceutiques contenant des azanaphtalenes WO1986007537A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AT86904018T ATE51150T1 (de) 1985-06-18 1986-06-18 Azanaphthalene enthaltende arzneimittelzusammensetzungen.
DE8686904018T DE3669656D1 (de) 1985-06-18 1986-06-18 Azanaphthalene enthaltende arzneimittelzusammensetzungen.
JP61503480A JPH0676322B2 (ja) 1985-06-18 1986-06-18 アザナフタレン含有医薬組成物
SG925/92A SG92592G (en) 1985-06-18 1992-09-11 Pharmaceutical compositions containing azanaphthalenes
HK93592A HK93592A (en) 1985-06-18 1992-11-26 Pharmaceutical compositions containing azanaphthalenes

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US74614985A 1985-06-18 1985-06-18
US746,149 1985-06-18
US808,404 1985-12-12
US06/808,404 US4945095A (en) 1985-12-12 1985-12-12 Method for suppressing the immune response
US839,308 1986-03-13
US06/839,308 US4666922A (en) 1985-06-18 1986-03-13 Method for modulating the immune response
US871,691 1986-06-12
US06/871,691 US4801589A (en) 1986-06-12 1986-06-12 Method for suppressing the immune response

Publications (2)

Publication Number Publication Date
WO1986007537A2 WO1986007537A2 (fr) 1986-12-31
WO1986007537A3 true WO1986007537A3 (fr) 1987-03-26

Family

ID=27505636

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1986/001298 WO1986007537A2 (fr) 1985-06-18 1986-06-18 Compositions pharmaceutiques contenant des azanaphtalenes

Country Status (6)

Country Link
EP (1) EP0228416B1 (fr)
JP (1) JPH0676322B2 (fr)
CA (1) CA1261754A (fr)
DE (1) DE3669656D1 (fr)
SG (1) SG92592G (fr)
WO (1) WO1986007537A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1309658C (fr) * 1986-12-05 1992-11-03 David J. Blythin Compositions pharmaceutiques pour le traitement des maladies hyperproliferatives de la peau
US5350755A (en) * 1986-12-05 1994-09-27 Schering Corporation Compounds and methods for treating hyperproliferative skin disease
GB0614471D0 (en) 2006-07-20 2006-08-30 Syngenta Ltd Herbicidal Compounds
JP4495201B2 (ja) 2007-10-10 2010-06-30 シャープ株式会社 画像処理装置、画像形成装置、画像処理方法、画像処理プログラムおよび画像処理プログラムを記録する記録媒体
CN114163446B (zh) * 2021-12-16 2023-11-21 中山大学 一种喹啉酮骨架的pde4抑制剂及其制备方法与应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0127135A2 (fr) * 1983-05-31 1984-12-05 Schering Corporation Dérivés condensés tricycliques de naphtyridinone et pyridone et les thiones correspondantes
EP0144996A2 (fr) * 1983-12-14 1985-06-19 Schering Corporation Dérivés substitués de spiro pyridine, compositions pharmaceutiques les contenant et procédés pour leur préparation et compositions
EP0092786B1 (fr) * 1982-04-26 1987-01-07 Schering Corporation Dérivés de la 1,8-naphtyridine et de la 1,5,8-azanaphtyridine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5854152B2 (ja) * 1976-03-25 1983-12-02 久光製薬株式会社 新規なナフチリジン誘導体

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0092786B1 (fr) * 1982-04-26 1987-01-07 Schering Corporation Dérivés de la 1,8-naphtyridine et de la 1,5,8-azanaphtyridine
EP0127135A2 (fr) * 1983-05-31 1984-12-05 Schering Corporation Dérivés condensés tricycliques de naphtyridinone et pyridone et les thiones correspondantes
EP0144996A2 (fr) * 1983-12-14 1985-06-19 Schering Corporation Dérivés substitués de spiro pyridine, compositions pharmaceutiques les contenant et procédés pour leur préparation et compositions

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, Volume 88, No. 15, 10 April 1978, (Columbus, Ohio, US), see page 570, Abstract 105298y, & JP, A, 77116495 (Hisamitsu Pharmaceutical Co. Inc.) 29-09-1977 cited in the application *
Goodman and Gilman's : "The Pharmacological Basis of Therapeutics", 7th edition 1985, MacMillan Publishing Company, (New York, US), pages 674-676, see pages 674-676 *

Also Published As

Publication number Publication date
CA1261754A (fr) 1989-09-26
JPS63500100A (ja) 1988-01-14
SG92592G (en) 1992-12-04
WO1986007537A2 (fr) 1986-12-31
JPH0676322B2 (ja) 1994-09-28
DE3669656D1 (de) 1990-04-26
EP0228416B1 (fr) 1990-03-21
EP0228416A1 (fr) 1987-07-15

Similar Documents

Publication Publication Date Title
EG17753A (en) Novel pharmacological compounds
HU895334D0 (en) Process for the preparation of nasal pharmaceutical compositions
IL77762A (en) 11beta-phenyl gonane derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL78858A0 (en) Imidazole analogs of mevalonolactone and derivatives thereof,their preparation and pharmaceutical compositions containing them
IL78079A0 (en) Sulphonylaminoethyl compounds,their preparation and pharmaceutical compositions containing them
IE870772L (en) Steroids
AU1578688A (en) Pharmaceutical composition, for oral administration, designed to attenuate the effects of beta-lactamines
PH23778A (en) Labdan compounds,pharmaceutical compositions and use
MY101784A (en) Novel pharmacological compounds
ZA877414B (en) New imidazo-benzoxazinones,the preparation thereof and pharmaceutical compositions containing these compounds
GB8613284D0 (en) Nasal pharmaceutical compositions
AU568920B2 (en) Pharmaceutical compositions of 3,4-dihydroisoquinolinium salts
DE3161216D1 (en) Use of 3,3'-azo-bis-(6-hydroxy benzoic acid) as a drug and pharmaceutical compositions containing the same
EP0255415A3 (en) Use of phenylethanolamines for the preparation of medicaments acting on gastrointestinal troubles
NZ220950A (en) 1,4-dihydro-4-oxo-quinoline-3-carboxylic acid derivatives and pharmaceutical compositions containing such compounds
IL79163A0 (en) 1,8-bridged 4-quinolone-3-carboxylic acids,their preparation,medicaments containing them and their use for the preparation of medicaments
WO1986007537A3 (fr) Compositions pharmaceutiques contenant des azanaphtalenes
IL91862A0 (en) Pharmaceutical compositions containing certain saccharides,some such novel compounds and their preparation
ES8802063A1 (es) Un procedimiento para la preparacion de nuevos compuestos poliprenilicos
DE3664036D1 (en) (1-phenylmethyl-5-hydroxy-1h-indazol-3-yl)-oxyacetic acid and salts thereof for use as a medicament, and pharmaceutical compositions containing them
PT83231A (en) Process for the preparation of gem-dihalo-1,8-diamino-4-aza-octanes and of pharmaceutical compositions containing the same
AU589781B2 (en) New derivatives of 4-phenyl-4-oxo-2-butenoic acid, their preparation process, their use as medicaments and the compositions containing them
IL78963A0 (en) N-phenyl-1-piperazine carboxamidines and related compounds,their preparation and pharmaceutical compositions containing them
IL78687A0 (en) Acylaminomethyl-penem compounds,their preparation and pharmaceutical compositions containing them
IL75166A (en) 2-substituted spiro(1,3-oxathiolane-5,3-quinuclidine)derivatives,their preparation and pharmaceutical compositions containing them and 3-hydroxy-3-mercaptomethylquinuclidine as intermidiate therefor

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): JP

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH DE FR GB IT LU NL SE

WWE Wipo information: entry into national phase

Ref document number: 1986904018

Country of ref document: EP

AK Designated states

Kind code of ref document: A3

Designated state(s): JP

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH DE FR GB IT LU NL SE

WWP Wipo information: published in national office

Ref document number: 1986904018

Country of ref document: EP

WWG Wipo information: grant in national office

Ref document number: 1986904018

Country of ref document: EP