WO1981002839A1 - Electrode device - Google Patents
Electrode device Download PDFInfo
- Publication number
- WO1981002839A1 WO1981002839A1 PCT/SE1981/000112 SE8100112W WO8102839A1 WO 1981002839 A1 WO1981002839 A1 WO 1981002839A1 SE 8100112 W SE8100112 W SE 8100112W WO 8102839 A1 WO8102839 A1 WO 8102839A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- electrode
- tube
- electrode unit
- unit
- cannula
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
Definitions
- This invention relates to an electrode device intended to be temporarily inserted into the body of a living being and essentially locally to treat biological body tissue therein and subsequently, upon completion of the treatment, to be removed, the said device incorporating an electrode unit introducable into the body tissue which it is intended to treat and a supply unit electrically insulated against other parts of the body for the supply of electricity from a voltage source to the said electrode unit.
- Various electrodes are already known, for example through the U.S. patents 4 103 690 and 3 348 548 and through the German patents 577 722, 651 428 and 1 143 937.
- Severe problems in the treatment of tissues also arise as a consequence of gas formation, dehydration and/or material deposition on the surfaces of the electrode.
- One of the objects of the present invention is to provide an electrode device which permits certain and exact insertion and retention as well as removal of the active electrode unit in a biological tissue without being moved out of position, for example in a tumour.
- a further object of the invention is to provide an electrode device with the aid of which gases generated at the surfaces of the electrode can be sucked out and liquid and/or medication can supplied to the tumour.
- Fig. 1 shows a cut-away view of an example of an embodiment of the electrode device according to the invention
- Fig. 2 shows a first stage in the introduction of the electrode device in the direction towards a tumour
- Fig. 3 shows the introduction of an aid, for example an anchoring device, in the tumour
- Fig. 4 shows the electrode device inserted with the aid of the anchoring device an'd a stiffening member, for example a cannula
- Fig. 5 shows the electrode device with the anchoring device and cannula removed.
- the electrode device is in the treatment position in the tumour and a three-way cock is connected to the supply unit for extraction of gas and/or introduction of liquid or medication.
- the embodiment of the electrode device shown in Fig. 1 comprises an electrode unit, manufactured for example of platinum and having a front section 1 with a pointed or narrowing cylindrical end 2 and one or more rear cylindrical rings 3, 3'. These parts have a diameter of approx. 1.9 mm.
- the electrode unit is shown here to consist of three parts to illustrate that electrode units with different axial lengths for tissue areas of different sizes can be built up from a standardized front section 1 and auxiliary rings 3, 3' since a large electrode surface is required in order to enable sufficiently large current intensities to pass through the tissu «e area to be treated within reasonable time.
- the front section 1 of the electrode unit which obviously can be used v/ithout auxiliary rings 3, 3', if for example a cancer tumour which is to be treated is of such a size that the length of the part 1 is sufficient, is attached by pressure to one end section of a supply unit 4 which in this case consists of a tube 4.
- This tube 4 is made pliable in order to be able to accompany movements in tissues and may be made for example of the plastic marketed under the trade mark Teflon.
- the rear rings 3 and 3' respectively are similarly attached by pressure to the tube 4.
- Attached to the inside of the cylindrical electrode section 1 are one or more electrical conductors 5, 6, 7, which are for example brazed or soldered. In the shown example, the conductors are three in number.
- the conductors 5-7 which in the same way as the electrode rings 1, 3, 3' are bright (blank) and thus uninsulated in the shown embodiment, are clamped between the cylindrical inner surfaces of the parts 3, 3' and the cylindrical jacket surface of the tube 4. By this means, good electrical contact is afforded between the electrical conductors 5-7 and the rings 3, 3'.
- the three conductors 5-7 are inserted into the interior of the tube 4 through a hole sited within the region for the ring 3', and are introduced via the interior of the tube 4 to, for example, one terminal 8, in the shown embodiment the positive terminal, of a direct voltage source 9.
- the second terminal of the latter is in this case connected to a second electrode 10 which is located at a suitable distance from the tube in a conductive medium in the body.
- medications such as cytostatics or antibiotics are desired in a high local concentration within a treatment area
- such medications can be attracted towards the electrical field of an electrode if the medication is imparted an electrical polarity which permits its electro-foretic attraction towards the electrode concerned.
- the medication can be administered in supply ducts, such as blood paths, gland paths, etc.
- the medication can also be administered via the electrod duct. If the same polarity is given to the electrode as to the medication, this is repelled in the tissue. If the opposite polarity is applied, the medication is rerained in the vicinity of the electrode.
- the tube 4 has an inner cylindrical duct which is largely equally as large as the cylindrical duct 11 in the front section of the electrode unit 1.
- a lug 23 for the end of the tube 4 By giving a lug 23 for the end of the tube 4, a slightly greater extent in the direction towards the centre than that corresponding to the wall thickness of the tube 4 in itself, an additional lug is obtained against which a cylindrical body or ball (not shown) connected with a stiff but pliable thin wire can be inserted in the tube 4 and act as a seal to close the opening in the end of the electrode unit 1 if necessary.
- a cannula with a diameter of approx. 1 mm may be introduced through the tube 4 and through this duct 11.
- the said cannula is provided with, for example, an obliquely ground off tip 13.
- the cannula 12 can be inserted into the position shown in Fig. 1, i.e. to a position beyond the end 2 of the electrode unit 1 and after insertion in the tissue together with the electrode unit will form a guide device for the electrode unit 1, 3. While the cannula 12 is being inserted in a tumour, it is possibly rotated around its longitudinal axis.
- a wireshaped anchoring device 14, 16, which in the embodiment example has a screw-shaped end section 14 which is terminated with a sharp point 15 is introducable into the cannula 12.
- the end of the anchoring device may instead be provided with other suitable means for improving the anchoring in and increasing the contact are against the tumour, for instance with hooks or barbs.
- the shell surface of the cannula 12 and/or the electrode unit 1 may be screw-shaped to facilitate introduction into and increase the contact surface against the tumour.
- the anchoring device designated by reference numeral 16 in Figs. 1 and 3 , extends throughout the entire cannula 12 and some way beyond the end of the cannula facing away from the tip 13 and is provided with a knob 17 by means of which the screw-shaped end section 14 can be rotated.
- the electrical conductors 5-7 emanate through a connector 18, for example in the form of a screw socket. In this position of the cannula socket 19 - see Fig. 2 - the cannula 12 is entirely inserted in the tube 4 and in the electrode unit 1 and protrudes beyond the electrode unit 1.
- Fig. 2-5 illustrate various stages in application of the electrode unit into a tumour 20 which is surrounded by body tissue 21.
- Fig. 2 shows how the electrode device has been passed through the body tissue 21 as far as the tumour 20 and the cannula 12 is here in its fully inserted position, whereupon the cannula socket 19 rests against the screw socket 18.
- the anchoring device 16 will be in such a position that its screw-shaped end 14 lies entirely retracted in the cannula 12.
- the anchoring device 16 is anchored by means of its tip 14, which may, for example, be screw-shaped, in the tumour 20.
- the tube 4 and the cannula 12 are retained in the position shown in Fig. 2 and the knob 17 - see Fig.
- the cannula socket 19 is passed inwards in the direction towards the tumour 20, whereby the cannula 12 and the electrode section 1 are moved in over the screw 14 and leave tumour cells in the threads of the latter - see Fig. 4.
- the anchoring device 16 serves as a guiding device for the cannula 12 and thus for the electrode unit, the cannula 12 also being rotatable during the movement in order to facilitate insertion.
- the electrode unit 1, 3, 3' is moved into the tumour 20 together with the cannula 12 and the cannula 12 serves during this movement as a support for the pliable supply unit 4 (the tube) and when the electrode unit 1, 3, 3' attached to the tube 4 reaches the intended position in the tumour 20, both the cannula 12 and the anchoring device 16 are withdrawn from the front section 1 of the electrode and out of the tube 4 with accompanying tumour material, which may be used to advantage for cytological check.
- the anchoring device 16 - either threaded or unthreaded - may in certain cases be used as a temporary electrode for local destruction of tissue around the anchoring device 16.
- the device is for example provided with a thin coating of electrical insulation, for example the plastic marketed under the trade mark Teflon, with the exception of the portion which is intended to be inserted into the tumour.
- Teflon the plastic marketed under the trade mark Teflon
- the anchoring device is then connected either to a suitably sited electrode for direct current treatment or to a large plate electrode applied to the surface of the body for application of high frequency alternating current.
- a cock 22 can now be inserted, as shown in Fig. 5, to the connector unit or the screw socket 18 in order to make possible, for example, the introduction of fluids or medication to the tumour 20 through the free duct in the tube 4 via perforations or holes (not shown) in this tube under the electrode units 1, 3, 3' and in or between the walls of the electrodes 1, 3, 3' and/or for removal of gas or fluid from the tumour 20.
- fluids or medication to the tumour 20 through the free duct in the tube 4 via perforations or holes (not shown) in this tube under the electrode units 1, 3, 3' and in or between the walls of the electrodes 1, 3, 3' and/or for removal of gas or fluid from the tumour 20.
- physiological sodium chloride solution may be introduced in order to increase the conductivity of the tumour 20 around the electrode unit. It is also possible for example to introduce cell poison.
- the cannula 12 which for example is made of stainless steel, should have a good fit against the electrode unit 1 and against the inside of the tube 4 but must slide easily in order to be insertable into and removable from the electrode unit 1 and the tube 4 without any greater effort.
- the anchoring device 16, which for example is made of stainless steel, has a good fit in the .cannula 12.
- the above described anchoring device 16 is made of rigid metal wire but it is also possible to use a flexible material, for instance spirally wound metal wire.
- a design is obtained which is soft, pliable and flexible and thus able to accompany tissue movements, for instance muscle movements, respiratory movements, etc. and can be introduced, for example, into a curved gall passage without being broken.
- the electrical conductors 5-7 are shown to run inside the tube 4 but they may obviously instead be -embedded in the wall of the tube A .
- the invention is primarily intended for treatment of cancer tumours in the human body but is naturally also usable in animal bodies and may similarly be used to treat other disease conditions in tissues.
Abstract
An electrode device for treatment of biological tissue comprising an electrode unit (1, 3, 3') and a supply unit (4) electrically insulated against the surrounds for sup ply of electricity from a voltage source to the said electrode unit (1, 3, 3'). The supply unit (4) is designed pliable and contains at least one duct for one or a plurality of electrical conductors (5-7) and for transport and guidance of aids (12-15, etc.) to and from the electrode unit (1, 3, 3').
Description
ELECTRODE DEVICE
This invention relates to an electrode device intended to be temporarily inserted into the body of a living being and essentially locally to treat biological body tissue therein and subsequently, upon completion of the treatment, to be removed, the said device incorporating an electrode unit introducable into the body tissue which it is intended to treat and a supply unit electrically insulated against other parts of the body for the supply of electricity from a voltage source to the said electrode unit. Various electrodes are already known, for example through the U.S. patents 4 103 690 and 3 348 548 and through the German patents 577 722, 651 428 and 1 143 937.
Known electrode designs for the treatment of biological tissue are unsuitable for several reasons. In order, for example, to treat a tumour with direct current, the electrode which is to be inserted in the tumour and which is arranged to electrically interact with a secondary electrode which is located outside the tumour must be localized with great precision in the centre of the tumour. With prior art electrodes, it is very difficult to achieve exact positioning and retention of the electrode in the tumour. One of the reasons for this is that the tissue and the tumour may move, for instance as a consequence of the respiratory motions of the patient. Moreover, the tumour, where the point of the electrode reaches to and is to be inserted into the tumour, may slide aside in surrounding softer tissue. This means that repeated attempts frequently have to be made in order for an acceptable positioning of the tumour to be obtained.
Severe problems in the treatment of tissues also arise as a consequence of gas formation, dehydration and/or material deposition on the surfaces of the electrode.
One of the objects of the present invention is to provide an electrode device which permits certain and exact insertion and retention as well as removal of the active electrode unit in a biological tissue without being moved out of position, for example in a tumour. A further object of the invention is to provide an electrode
device with the aid of which gases generated at the surfaces of the electrode can be sucked out and liquid and/or medication can supplied to the tumour.
These and other objects are obtained at the electrode device specified in the descriptive preamble according to the present invention in that said device is given the features as are evident from the characterizing clause of the accompanying Claim 1.
Other essential features of the present invention are evident from the accompanying claims. One embodiment of the invention is described below and with reference to the accompanying drawings, wherein Fig. 1 shows a cut-away view of an example of an embodiment of the electrode device according to the invention, Fig. 2 shows a first stage in the introduction of the electrode device in the direction towards a tumour, Fig. 3 shows the introduction of an aid, for example an anchoring device, in the tumour, Fig. 4 shows the electrode device inserted with the aid of the anchoring device an'd a stiffening member, for example a cannula, and Fig. 5 shows the electrode device with the anchoring device and cannula removed. According to Fig. 5, the electrode device is in the treatment position in the tumour and a three-way cock is connected to the supply unit for extraction of gas and/or introduction of liquid or medication.
The embodiment of the electrode device shown in Fig. 1 comprises an electrode unit, manufactured for example of platinum and having a front section 1 with a pointed or narrowing cylindrical end 2 and one or more rear cylindrical rings 3, 3'. These parts have a diameter of approx. 1.9 mm. The electrode unit is shown here to consist of three parts to illustrate that electrode units with different axial lengths for tissue areas of different sizes can be built up from a standardized front section 1 and auxiliary rings 3, 3' since a large electrode surface is required in order to enable sufficiently large current intensities to pass through the tissu «e area to be treated within reasonable time.
The front section 1 of the electrode unit, which obviously can be used v/ithout auxiliary rings 3, 3', if for example a cancer tumour which is to be treated is of such a size that the length of the part 1 is sufficient, is attached by pressure to one end section of a
supply unit 4 which in this case consists of a tube 4. This tube 4 is made pliable in order to be able to accompany movements in tissues and may be made for example of the plastic marketed under the trade mark Teflon. The rear rings 3 and 3' respectively are similarly attached by pressure to the tube 4. Attached to the inside of the cylindrical electrode section 1 are one or more electrical conductors 5, 6, 7, which are for example brazed or soldered. In the shown example, the conductors are three in number. The conductors 5-7 which in the same way as the electrode rings 1, 3, 3' are bright (blank) and thus uninsulated in the shown embodiment, are clamped between the cylindrical inner surfaces of the parts 3, 3' and the cylindrical jacket surface of the tube 4. By this means, good electrical contact is afforded between the electrical conductors 5-7 and the rings 3, 3'. The three conductors 5-7 are inserted into the interior of the tube 4 through a hole sited within the region for the ring 3', and are introduced via the interior of the tube 4 to, for example, one terminal 8, in the shown embodiment the positive terminal, of a direct voltage source 9. The second terminal of the latter is in this case connected to a second electrode 10 which is located at a suitable distance from the tube in a conductive medium in the body.
We have thus been able to show that the walls of the blood vessels function as insulators around a conductive medium - the blood plasma. Since a tumour is supplied by th.e surrounding blood vessels, a closed electrical circuit is obtained by this means, with the blood vessels acting as mutually parallel electric conductors. Other conductive media in the body may nevertheless be used, for example tissue fluid, brain fluid, gall fluid, urine, gland secretion, etc.
When an electrode which is inserted in a tumour acts as a positive electrode, a powerful emission of protones is obtained upon decomposition of water, resulting in the tissue becoming highly acidic and in destruction of the tumour close to the electrode. Tumour cells possess negative surplus charges and are therefore retained by the positive electrode. At the same time, gas - for example chlorine gas and oxygen gas - is generated at the positive electrode and the gases deposit themselves on the surface of the electrode, thus impeding the process. Further biological effects in the electrical field have been
revealed and consist of electro-osmosis, electroforetic transports, accumulation of white blood corpuscles around the anode and extended formation of blood clots in the capillaries around the anode, all factors contributing to the treatment.
If medications such as cytostatics or antibiotics are desired in a high local concentration within a treatment area, such medications can be attracted towards the electrical field of an electrode if the medication is imparted an electrical polarity which permits its electro-foretic attraction towards the electrode concerned. In this case, the medication can be administered in supply ducts, such as blood paths, gland paths, etc. By means of the present invention, the medication can also be administered via the electrod duct. If the same polarity is given to the electrode as to the medication, this is repelled in the tissue. If the opposite polarity is applied, the medication is rerained in the vicinity of the electrode.
The tube 4 has an inner cylindrical duct which is largely equally as large as the cylindrical duct 11 in the front section of the electrode unit 1. By giving a lug 23 for the end of the tube 4, a slightly greater extent in the direction towards the centre than that corresponding to the wall thickness of the tube 4 in itself, an additional lug is obtained against which a cylindrical body or ball (not shown) connected with a stiff but pliable thin wire can be inserted in the tube 4 and act as a seal to close the opening in the end of the electrode unit 1 if necessary. A cannula with a diameter of approx. 1 mm may be introduced through the tube 4 and through this duct 11. The said cannula is provided with, for example, an obliquely ground off tip 13. The cannula 12 can be inserted into the position shown in Fig. 1, i.e. to a position beyond the end 2 of the electrode unit 1 and after insertion in the tissue together with the electrode unit will form a guide device for the electrode unit 1, 3. While the cannula 12 is being inserted in a tumour, it is possibly rotated around its longitudinal axis. A wireshaped anchoring device 14, 16, which in the embodiment example has a screw-shaped end section 14 which is terminated with a sharp point 15 is introducable into the cannula 12. The end of the anchoring device may instead be provided with other suitable means for improving the anchoring in and
increasing the contact are against the tumour, for instance with hooks or barbs.
As an alternative or a complement, the shell surface of the cannula 12 and/or the electrode unit 1 may be screw-shaped to facilitate introduction into and increase the contact surface against the tumour.
The anchoring device, designated by reference numeral 16 in Figs. 1 and 3 , extends throughout the entire cannula 12 and some way beyond the end of the cannula facing away from the tip 13 and is provided with a knob 17 by means of which the screw-shaped end section 14 can be rotated. The electrical conductors 5-7 emanate through a connector 18, for example in the form of a screw socket. In this position of the cannula socket 19 - see Fig. 2 - the cannula 12 is entirely inserted in the tube 4 and in the electrode unit 1 and protrudes beyond the electrode unit 1.
Fig. 2-5 illustrate various stages in application of the electrode unit into a tumour 20 which is surrounded by body tissue 21.
Fig. 2 shows how the electrode device has been passed through the body tissue 21 as far as the tumour 20 and the cannula 12 is here in its fully inserted position, whereupon the cannula socket 19 rests against the screw socket 18. When the tip of the cannula 12 has reached as far as the tumour 20, the anchoring device 16 will be in such a position that its screw-shaped end 14 lies entirely retracted in the cannula 12. In the next stage, the anchoring device 16 is anchored by means of its tip 14, which may, for example, be screw-shaped, in the tumour 20. For this purpose, the tube 4 and the cannula 12 are retained in the position shown in Fig. 2 and the knob 17 - see Fig. 3 - is turned in the entry direction of the screw-shaped tip 14 under light axial pressure. The tip 15 of the crew 14 first reaches the occasionally relatively hard tumour tissue and easily penetrates the surface of the rumour without essentially disturbing the position of the tumour 20. As the knob 17 continues to be turned, the screw 14 is drilled into the tumour 20, forming a reliable anchorage for the entire electrode device - see Fig. 3. When the screw has reached its intended position in the tumour 20 - something which in certain cases
may require repeated attempts - which position may, for example, be checked by X-ray fluoroscopy, the cannula socket 19 is passed inwards in the direction towards the tumour 20, whereby the cannula 12 and the electrode section 1 are moved in over the screw 14 and leave tumour cells in the threads of the latter - see Fig. 4. In this position, the anchoring device 16 serves as a guiding device for the cannula 12 and thus for the electrode unit, the cannula 12 also being rotatable during the movement in order to facilitate insertion. The electrode unit 1, 3, 3' is moved into the tumour 20 together with the cannula 12 and the cannula 12 serves during this movement as a support for the pliable supply unit 4 (the tube) and when the electrode unit 1, 3, 3' attached to the tube 4 reaches the intended position in the tumour 20, both the cannula 12 and the anchoring device 16 are withdrawn from the front section 1 of the electrode and out of the tube 4 with accompanying tumour material, which may be used to advantage for cytological check.
The anchoring device 16 - either threaded or unthreaded - may in certain cases be used as a temporary electrode for local destruction of tissue around the anchoring device 16. In this case, the device is for example provided with a thin coating of electrical insulation, for example the plastic marketed under the trade mark Teflon, with the exception of the portion which is intended to be inserted into the tumour. The anchoring device is then connected either to a suitably sited electrode for direct current treatment or to a large plate electrode applied to the surface of the body for application of high frequency alternating current. When heat develops around the non-isolated part of the anchoring device in the tumour, local tissue destruction is accomplished which has a therapeutical effect and gives a lengthwise extending tissue cavity, into which, for example, the cannula 12 and the electrode unit 1, 3, 3' can thus be more easily inserted.
At this juncture, a cock 22 can now be inserted, as shown in Fig. 5, to the connector unit or the screw socket 18 in order to make possible, for example, the introduction of fluids or medication to the tumour 20 through the free duct in the tube 4 via perforations or holes (not shown) in this tube under the electrode units 1, 3, 3' and
in or between the walls of the electrodes 1, 3, 3' and/or for removal of gas or fluid from the tumour 20. For example, physiological sodium chloride solution may be introduced in order to increase the conductivity of the tumour 20 around the electrode unit. It is also possible for example to introduce cell poison.
The cannula 12, which for example is made of stainless steel, should have a good fit against the electrode unit 1 and against the inside of the tube 4 but must slide easily in order to be insertable into and removable from the electrode unit 1 and the tube 4 without any greater effort. The anchoring device 16, which for example is made of stainless steel, has a good fit in the .cannula 12.
The above described anchoring device 16 is made of rigid metal wire but it is also possible to use a flexible material, for instance spirally wound metal wire. Through the elaboration of the electrode device, a design is obtained which is soft, pliable and flexible and thus able to accompany tissue movements, for instance muscle movements, respiratory movements, etc. and can be introduced, for example, into a curved gall passage without being broken.
In the drawings, the electrical conductors 5-7 are shown to run inside the tube 4 but they may obviously instead be -embedded in the wall of the tube A .
The invention is primarily intended for treatment of cancer tumours in the human body but is naturally also usable in animal bodies and may similarly be used to treat other disease conditions in tissues.
Claims
1. An electrode device designed to be temporarily introduced into the body of a living being and essentially locally to treat biological body tissue therein and to be subsequently removed upon completion of the treatment, the said device comprising an electrode unit (1, 3, 3'), introducable into the body tissue which is intended to be treated and a supply unit (4) insulated electrically against other body parts for supply of electricity from a voltage source (9) to the said electrode unit (1, 3, 3'), c h a r a c t e r i z e d in that the said insulated supply unit (4) is elaborated pliably and contains at least one duct, the length of which is so adapted that the duct emanates both in the said electrode unit (1, 3, 3') and outside the body and which is so adapted in size that it incorporates not only a space which is electrically insulated against such parts of the body which are not intended to be treated for one or a plurality of electrical conductors (5-7) for excitation of the electrode unit (1, 3, 3') but also a space limited against those parts of the body which are not intended to be treated but open or openable towards the body tissue which it is intended to treat for transport and/or guidance to and from the treatment point of aids for temporary stiffening of the pliable supply unit (4), to facilitate introduction and anchoring of the electrode unit (1, 3, 3') in the intended position in the body, sampling of body tissue, supplementary treatment of the body tissue and/or removal of residual products from the treatment site.
2. An electrode device according to Claim 1, c h a r a c t e r i z e d in that the said spaces coincide, in that the supply unit (4) is elaborated as a tube and in that the said electric conductors (5-7) run in the tube (4).
3. An electrode device according to Claim 2, . c h a r a c t e r i z e d in that the said electrode unit (1, 3, 3') is provided in its end facing away from the said tube (4) with an opening which is preferably located as an axial elongation of the mouth of the tube (4) in the electrode unit (1, 3, 3').
4. An electrode device according to Claim 3, c h a r a c t e r i z e d in that the electrode unit (1, 3, 3') in the said end is elaborated narrowingly (2), viewed in the direction of the electrode unit (1, 3, 3') away from the tube (4).
5. An electrode device according to Claim 3 or Claim 4, c h a r a c t e r i z e d in that the electrode unit (1, 3, 3') contains or surrounds a portion of one end of the tube (4) and in that the wall of the tube (4) within that portion of its one end which is contained or surrounded by the electrode unit (1, 3, 3') is provided with holes which are arranged to provide fluid and gas communication between the interior of the tube (4) and the outer surface of the tube (4) and of which at least one hole also serves to introduce the said electric conductors (5-7) to contact with the electrode unit (1, 3, 3').
6. An electrode device according to Claim 5, c h a r a c t e r i z e d in that the hole in the wall of the tube (4) for the electric conductors (5-7) is located at such a distance from one end of the tube (4) that a number of electrode units (1, 3, 3') can be attached to the tube (4) and electrically contact the said electrical conductors (5-7) and in that the said electrode units (1, 3. 3') are so mutually adapted and/or provided with such holes or slots that fluid and gas communication is obtained between the outer surfaces of the said electrode units (1, 3, 3') and the outer surface of the tube (4).
7. An electrode device according ti Claim 6, c h a r a c t e r i z e d in that the aggregate length of the insulated supply unit (4) and the electrode unit (1, 3, 3') and the opening of the said closed space are so adapted in relation to the length and outside dimensions of a cannula (12) serving as a stiffening body that the cannula (12) can be inserted into the said closed space and protrude beyond the portion of the electrode unit situated furthest away from the said duct and in that the said cannula (12) in itself or a device (14, 16) movable in the said cannula (12) is elaborated as an anchoring device, which is arranged to be inserted into and anchored in relation to a biological tissue, into which at least the electrode unit (1, 3, 3') is to be inserted, and in that the electrode device is arranged to be movable relative to the cannula (12) and/or the said unit (14, 16).
8. An electrode device according to Claim 7, c h a r a c t e r i z e d in that the electrode unit (1, 3, 3'), the cannula (12) and/or the anchoring device (14) are elaborated with barbs, screw shape or similar irregularities to increase the contact surface.
9. An electrode device according to any of Claims 2-8, c h a r a c t e r i z e d in that the other end of the tube (4) is furnished with a connector (18).
10. An electrode device according to any of Claims 2-9, c h a r a c t e r i z e d in that the electrode unit (1) is provided with an inner stop lug (23).
11. An electrode device according to Claim 10, c h a r a c t e r i z e d in that one end of the tube (4) is arranged to be stopped by the said stop lug (23) in the interior of the electrode unit (1) and in that the said stop lug (23) has an extent which in the direction towards the centre of the electrode unit (1) exceeds the wall thickness of the tube (4) in the same direction, whereby apart from a stop for the tube (4) an additional stop is also obtained against which, for example, a ball or cylinder equipped with a wire can be made to rest to form a seal.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE8181900930T DE3168107D1 (en) | 1980-04-11 | 1981-04-10 | Electrode device |
DK534181A DK151612C (en) | 1980-04-11 | 1981-12-01 | electrode |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8002772 | 1980-04-11 | ||
SE8002772A SE422885B (en) | 1980-04-11 | 1980-04-11 | The electrode device |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1981002839A1 true WO1981002839A1 (en) | 1981-10-15 |
Family
ID=20340731
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/SE1981/000112 WO1981002839A1 (en) | 1980-04-11 | 1981-04-10 | Electrode device |
Country Status (7)
Country | Link |
---|---|
US (1) | US4572214A (en) |
EP (1) | EP0056801B1 (en) |
JP (1) | JPS57500630A (en) |
AU (1) | AU547735B2 (en) |
DK (1) | DK151612C (en) |
SE (1) | SE422885B (en) |
WO (1) | WO1981002839A1 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0316995A1 (en) * | 1987-11-13 | 1989-05-24 | Björn Nordenström | Electrode device intended to be introduced into the body of a living being |
EP0361762A2 (en) * | 1988-09-22 | 1990-04-04 | Med Institute, Inc. | Apparatus for treating tissue |
US6656918B2 (en) * | 1995-08-03 | 2003-12-02 | Johns Hopkins University School Of Medicine | Prophylactic and therapeutic treatment of the ductal epithelium of a mammary gland for cancer |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
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SE455920B (en) * | 1986-01-29 | 1988-08-22 | Hans Wiksell | TUMOR HYPERTERMY TREATMENT DEVICE |
US4989601A (en) * | 1988-05-02 | 1991-02-05 | Medical Engineering & Development Institute, Inc. | Method, apparatus, and substance for treating tissue having neoplastic cells |
US4920978A (en) * | 1988-08-31 | 1990-05-01 | Triangle Research And Development Corporation | Method and apparatus for the endoscopic treatment of deep tumors using RF hyperthermia |
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US7720549B2 (en) * | 2004-04-06 | 2010-05-18 | Oncostim, Inc. | Partially implantable system for the electrical treatment of abnormal tissue growth |
US20050222646A1 (en) * | 2004-04-06 | 2005-10-06 | Kai Kroll | Method and device for treating cancer with modified output electrical therapy |
RU2007143298A (en) | 2005-04-22 | 2009-05-27 | Экпойнт Медикал Инк. (Us) | THERAPEUTIC TREATMENT OF DC FABRIC |
US7879034B2 (en) | 2006-03-02 | 2011-02-01 | Arthrocare Corporation | Internally located return electrode electrosurgical apparatus, system and method |
US10736689B2 (en) | 2008-08-20 | 2020-08-11 | Prostacare Pty Ltd | Low-corrosion electrode for treating tissue |
US20100114110A1 (en) * | 2008-10-30 | 2010-05-06 | Arthrocare Corporation | Intervertebral disc access assembly |
US8979838B2 (en) | 2010-05-24 | 2015-03-17 | Arthrocare Corporation | Symmetric switching electrode method and related system |
US20150025350A1 (en) * | 2013-07-19 | 2015-01-22 | Biotronik Se & Co. Kg | Electrode With Guide Tunnel for a Cannula, and Kit Comprising Electrode and Cannula |
KR20190001355U (en) | 2017-11-27 | 2019-06-07 | 프로스타캐어 피티와이 엘티디 | An apparatus and a method for the treatment of a prostatic disease |
US11224474B2 (en) | 2018-02-28 | 2022-01-18 | Prostacare Pty Ltd | System for managing high impedance changes in a non-thermal ablation system for BPH |
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DE577722C (en) * | 1931-12-12 | 1933-06-03 | Pierre Denis Bernard | Electrode for electrotherapeutic dental treatment |
DE651428C (en) * | 1935-12-13 | 1937-10-13 | Koch & Sterzel Akt Ges | Electrode for electro-medical purposes, preferably coagulation electrode, for connection to a high-frequency apparatus |
DE1143937B (en) * | 1960-07-01 | 1963-02-21 | Mikrowellen Ges M B H Deutsche | Arrangement for the therapeutic treatment of tumors with microwaves |
US4103690A (en) * | 1977-03-21 | 1978-08-01 | Cordis Corporation | Self-suturing cardiac pacer lead |
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US3411507A (en) * | 1964-04-01 | 1968-11-19 | Medtronic Inc | Method of gastrointestinal stimulation with electrical pulses |
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JPS4421596Y1 (en) * | 1965-09-16 | 1969-09-12 | ||
US3769984A (en) * | 1971-03-11 | 1973-11-06 | Sherwood Medical Ind Inc | Pacing catheter with frictional fit lead attachment |
US3737579A (en) * | 1971-04-19 | 1973-06-05 | Medtronic Inc | Body tissue electrode and device for screwing the electrode into body tissue |
DE2324658B2 (en) * | 1973-05-16 | 1977-06-30 | Richard Wolf Gmbh, 7134 Knittlingen | PROBE FOR COAGULATING BODY TISSUE |
US3952742A (en) * | 1974-06-12 | 1976-04-27 | Taylor Duane F | Needle-carried, transthoracic, cannula-type cardiac resuscitation instrument |
US3974834A (en) * | 1975-04-23 | 1976-08-17 | Medtronic, Inc. | Body-implantable lead |
US4044774A (en) * | 1976-02-23 | 1977-08-30 | Medtronic, Inc. | Percutaneously inserted spinal cord stimulation lead |
CA1109746A (en) * | 1976-05-10 | 1981-09-29 | Shelby M. Baylis | Biopsy apparatus and methods of constructing and utilizing same |
JPS5383384A (en) * | 1976-12-28 | 1978-07-22 | Seiko Instr & Electronics | Lead for heart pacemaker |
-
1980
- 1980-04-11 SE SE8002772A patent/SE422885B/en not_active IP Right Cessation
-
1981
- 1981-04-10 EP EP81900930A patent/EP0056801B1/en not_active Expired
- 1981-04-10 AU AU70309/81A patent/AU547735B2/en not_active Ceased
- 1981-04-10 JP JP56501242A patent/JPS57500630A/ja active Pending
- 1981-04-10 WO PCT/SE1981/000112 patent/WO1981002839A1/en active IP Right Grant
- 1981-04-10 US US06/328,581 patent/US4572214A/en not_active Expired - Fee Related
- 1981-12-01 DK DK534181A patent/DK151612C/en not_active IP Right Cessation
Patent Citations (4)
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DE577722C (en) * | 1931-12-12 | 1933-06-03 | Pierre Denis Bernard | Electrode for electrotherapeutic dental treatment |
DE651428C (en) * | 1935-12-13 | 1937-10-13 | Koch & Sterzel Akt Ges | Electrode for electro-medical purposes, preferably coagulation electrode, for connection to a high-frequency apparatus |
DE1143937B (en) * | 1960-07-01 | 1963-02-21 | Mikrowellen Ges M B H Deutsche | Arrangement for the therapeutic treatment of tumors with microwaves |
US4103690A (en) * | 1977-03-21 | 1978-08-01 | Cordis Corporation | Self-suturing cardiac pacer lead |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0316995A1 (en) * | 1987-11-13 | 1989-05-24 | Björn Nordenström | Electrode device intended to be introduced into the body of a living being |
US4974595A (en) * | 1987-11-13 | 1990-12-04 | Nordenstroem Bjoern | Electrode device intended to be introduced into the body of a living being |
EP0361762A2 (en) * | 1988-09-22 | 1990-04-04 | Med Institute, Inc. | Apparatus for treating tissue |
EP0361762A3 (en) * | 1988-09-22 | 1992-01-08 | Med Institute, Inc. | Apparatus for treating tissue |
US6656918B2 (en) * | 1995-08-03 | 2003-12-02 | Johns Hopkins University School Of Medicine | Prophylactic and therapeutic treatment of the ductal epithelium of a mammary gland for cancer |
US7196070B2 (en) | 1995-08-03 | 2007-03-27 | Johns Hopkins University School Of Medicine | Prophylactic and therapeutic treatment of the ductal epithelium of a mammary gland for cancer |
Also Published As
Publication number | Publication date |
---|---|
DK151612C (en) | 1988-07-11 |
DK534181A (en) | 1981-12-01 |
AU7030981A (en) | 1981-10-26 |
JPS57500630A (en) | 1982-04-15 |
DK151612B (en) | 1987-12-21 |
EP0056801A1 (en) | 1982-08-04 |
AU547735B2 (en) | 1985-10-31 |
SE422885B (en) | 1982-04-05 |
EP0056801B1 (en) | 1985-01-09 |
US4572214A (en) | 1986-02-25 |
SE8002772L (en) | 1981-10-12 |
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