UY38883A - Anticuerpos contra el factor de las células madre, y métodos de uso de ellas - Google Patents

Anticuerpos contra el factor de las células madre, y métodos de uso de ellas

Info

Publication number
UY38883A
UY38883A UY0001038883A UY38883A UY38883A UY 38883 A UY38883 A UY 38883A UY 0001038883 A UY0001038883 A UY 0001038883A UY 38883 A UY38883 A UY 38883A UY 38883 A UY38883 A UY 38883A
Authority
UY
Uruguay
Prior art keywords
methods
stem cell
cell factor
antibodies
antibodies against
Prior art date
Application number
UY0001038883A
Other languages
English (en)
Spanish (es)
Inventor
Martin Phillips
Original Assignee
Opsidio Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Opsidio Llc filed Critical Opsidio Llc
Publication of UY38883A publication Critical patent/UY38883A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77Internalization into the cell
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
UY0001038883A 2019-09-16 2020-09-16 Anticuerpos contra el factor de las células madre, y métodos de uso de ellas UY38883A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201962900927P 2019-09-16 2019-09-16

Publications (1)

Publication Number Publication Date
UY38883A true UY38883A (es) 2021-04-30

Family

ID=74868426

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001038883A UY38883A (es) 2019-09-16 2020-09-16 Anticuerpos contra el factor de las células madre, y métodos de uso de ellas

Country Status (28)

Country Link
US (5) US20220324957A1 (https=)
EP (3) EP4031569B1 (https=)
JP (4) JP7698635B2 (https=)
KR (1) KR20220079561A (https=)
CN (2) CN118561997A (https=)
AR (1) AR119979A1 (https=)
AU (2) AU2020348295A1 (https=)
BR (1) BR112022004776A2 (https=)
CA (2) CA3154649A1 (https=)
CL (1) CL2022000633A1 (https=)
CO (1) CO2022003661A2 (https=)
DK (1) DK4031569T3 (https=)
DO (1) DOP2022000058A (https=)
EC (1) ECSP22022676A (https=)
ES (1) ES3053942T3 (https=)
FI (1) FI4031569T3 (https=)
IL (1) IL291385A (https=)
MX (1) MX2022003159A (https=)
PE (1) PE20230090A1 (https=)
PH (1) PH12022550647A1 (https=)
PL (1) PL4031569T3 (https=)
PT (1) PT4031569T (https=)
SA (1) SA522431966B1 (https=)
TW (2) TWI875812B (https=)
UA (1) UA129546C2 (https=)
UY (1) UY38883A (https=)
WO (2) WO2021055408A1 (https=)
ZA (1) ZA202203272B (https=)

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AU2019265019B2 (en) 2018-05-11 2025-11-06 Beam Therapeutics Inc. Methods of substituting pathogenic amino acids using programmable base editor systems
AU2020348295A1 (en) * 2019-09-16 2022-04-07 Insmed Incorporated Anti-stem cell factor antibodies and methods of use thereof
KR20250167153A (ko) * 2023-03-03 2025-11-28 셀덱스 쎄라퓨틱스, 인크. 항-줄기 세포 인자(scf) 및 항-흉선 기질 림포포이에틴(tslp) 항체, 및 이중특이적 구축물
WO2026079764A1 (ko) * 2024-10-10 2026-04-16 아주대학교산학협력단 마우스 scf를 중화하는 항체 및 이의 용도

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JP2657113B2 (ja) * 1989-10-16 1997-09-24 アムジエン・インコーポレーテツド 幹細胞因子
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GB8928874D0 (en) 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
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US5911988A (en) 1995-04-28 1999-06-15 Bayer Corporation Method for treating asthma using SCF antibody
JP3583214B2 (ja) 1995-12-01 2004-11-04 株式会社ニチレイ ヒトscfに対するモノクローナル抗体
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AR037756A1 (es) * 2001-12-17 2004-12-01 Bayer Corp Anticuerpo que inhibe la actividad del factor de las celulas precursoras y su uso para el tratamiento del asma.
US7902338B2 (en) 2003-07-31 2011-03-08 Immunomedics, Inc. Anti-CD19 antibodies
PL1691837T3 (pl) 2003-12-10 2012-11-30 Squibb & Sons Llc IP-10 przeciwciała i ich zastosowanie
US7611707B2 (en) 2004-04-29 2009-11-03 Otsuka Pharmaceutical Co., Ltd. Glycoprotein VI antibodies and methods thereof
WO2006002064A2 (en) 2004-06-14 2006-01-05 Aerovance, Inc. Antibody inhibiting stem cell factor activity and use for treatment of asthma
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US20110189093A1 (en) 2008-04-14 2011-08-04 Proscan Rx Pharma Prostate specific membrane antigen antibodies and antigen binding fragments
AU2012205718B2 (en) 2011-01-10 2017-07-06 The Regents Of The University Of Michigan Stem cell factor inhibitor
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KR101384360B1 (ko) 2012-05-04 2014-04-14 아주대학교산학협력단 Scf 또는 이의 수용체를 억제하는 물질을 포함하는 혈관 투과성 관련 질환의 치료 또는 예방용 조성물
NZ630363A (en) 2012-07-25 2018-09-28 Celldex Therapeutics Inc Anti-kit antibodies and uses thereof
US10927153B1 (en) 2015-05-20 2021-02-23 University Of South Florida Synthetic plasmodium antigens, compositions, and uses thereof
KR102438650B1 (ko) * 2015-08-19 2022-08-31 화이자 인코포레이티드 조직 인자 경로 억제제 항체 및 그의 용도
KR20170022409A (ko) 2015-08-20 2017-03-02 주식회사 와이바이오로직스 Scf 특이적 항체
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Also Published As

Publication number Publication date
US20220324957A1 (en) 2022-10-13
BR112022004776A2 (pt) 2022-06-21
EP4031176A4 (en) 2023-11-29
CL2022000633A1 (es) 2022-11-11
CA3154649A1 (en) 2021-03-25
FI4031569T3 (fi) 2025-11-14
AU2020351138A1 (en) 2022-03-31
EP4031176A1 (en) 2022-07-27
JP7717687B2 (ja) 2025-08-04
PT4031569T (pt) 2025-11-12
JP7698635B2 (ja) 2025-06-25
UA129546C2 (uk) 2025-05-28
US20230019680A1 (en) 2023-01-19
EP4031569B1 (en) 2025-08-20
EP4031569A4 (en) 2023-10-18
WO2021055408A1 (en) 2021-03-25
JP2025165991A (ja) 2025-11-05
IL291385A (en) 2022-05-01
CN114729036B (zh) 2024-07-02
WO2021055409A1 (en) 2021-03-25
US20210079084A1 (en) 2021-03-18
EP4650367A3 (en) 2026-03-04
ES3053942T3 (en) 2026-01-28
TW202523696A (zh) 2025-06-16
PL4031569T3 (pl) 2026-02-16
PH12022550647A1 (en) 2023-03-27
CA3154648A1 (en) 2021-03-25
US12410246B2 (en) 2025-09-09
JP2022547733A (ja) 2022-11-15
MX2022003159A (es) 2022-04-07
US11939373B2 (en) 2024-03-26
CN114729036A (zh) 2022-07-08
PE20230090A1 (es) 2023-01-16
TWI875812B (zh) 2025-03-11
EP4031569A1 (en) 2022-07-27
AU2020348295A1 (en) 2022-04-07
CO2022003661A2 (es) 2022-04-08
DOP2022000058A (es) 2022-08-31
ECSP22022676A (es) 2022-05-31
DK4031569T3 (da) 2025-11-17
JP2025125563A (ja) 2025-08-27
US20220340655A1 (en) 2022-10-27
TW202124434A (zh) 2021-07-01
SA522431966B1 (ar) 2025-05-18
AR119979A1 (es) 2022-01-26
ZA202203272B (en) 2022-12-21
CN118561997A (zh) 2024-08-30
JP2022548646A (ja) 2022-11-21
KR20220079561A (ko) 2022-06-13
US20240076367A1 (en) 2024-03-07
EP4650367A2 (en) 2025-11-19

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Effective date: 20260126