UY35921A - Necrostatina-1 y derivados como retardadores de la degeneración axonal - Google Patents

Necrostatina-1 y derivados como retardadores de la degeneración axonal

Info

Publication number
UY35921A
UY35921A UY0001035921A UY35921A UY35921A UY 35921 A UY35921 A UY 35921A UY 0001035921 A UY0001035921 A UY 0001035921A UY 35921 A UY35921 A UY 35921A UY 35921 A UY35921 A UY 35921A
Authority
UY
Uruguay
Prior art keywords
necrostatin
retainers
derivatives
axonal degeneration
useful
Prior art date
Application number
UY0001035921A
Other languages
English (en)
Inventor
Washington Nicolás Martínez Alarcón
Felipe Alfredo Court Goldsmith
Original Assignee
Pontificia Universidad Católica De Chile
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pontificia Universidad Católica De Chile filed Critical Pontificia Universidad Católica De Chile
Publication of UY35921A publication Critical patent/UY35921A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

Se describen la Necrostatina-1 y compuestos derivados de dicha molécula o sus sales farmacéuticamente aceptables útiles para tratar enfermedades de degeneración axonal. También se divulgan métodos terapéuticos útiles apra tratamientos médicos.
UY0001035921A 2013-12-30 2014-12-24 Necrostatina-1 y derivados como retardadores de la degeneración axonal UY35921A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CL2013003785A CL2013003785A1 (es) 2013-12-30 2013-12-30 Uso de necrostatina-1 para el tratamiento de la degeneracion axonal inducida por daños agudos y cronicos

Publications (1)

Publication Number Publication Date
UY35921A true UY35921A (es) 2015-06-30

Family

ID=53492873

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001035921A UY35921A (es) 2013-12-30 2014-12-24 Necrostatina-1 y derivados como retardadores de la degeneración axonal

Country Status (4)

Country Link
AR (1) AR098778A1 (es)
CL (1) CL2013003785A1 (es)
UY (1) UY35921A (es)
WO (1) WO2015100511A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11382889B2 (en) 2018-04-19 2022-07-12 Institut D'investigació Biomèdica De Bellvitge (Idibell) NRF2 activators for the prevention and/or treatment of axonal degeneration

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8324262B2 (en) * 2005-12-20 2012-12-04 The Brigham And Women's Hospital, Inc. Tricyclic necrostatin compounds
EP2773341A2 (en) * 2011-10-21 2014-09-10 Massachusetts Eye & Ear Infirmary Compositions comprising necrosis inhibitors, such as necrostatins, alone or in combination, for promoting axon regeneration and nerve function, thereby treating cns disorders

Also Published As

Publication number Publication date
AR098778A1 (es) 2016-06-15
WO2015100511A1 (es) 2015-07-09
CL2013003785A1 (es) 2014-07-11

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Legal Events

Date Code Title Description
104 Application deemed to be withdrawn (no substantive examination fee paid)

Effective date: 20201204