UY35159A - UK-2 BIOSYNTHETIC GEN AND METHOD FOR IMPROVING THE PRODUCTIVITY OF UK-2 USING SUCH GEN - Google Patents
UK-2 BIOSYNTHETIC GEN AND METHOD FOR IMPROVING THE PRODUCTIVITY OF UK-2 USING SUCH GENInfo
- Publication number
- UY35159A UY35159A UY0001035159A UY35159A UY35159A UY 35159 A UY35159 A UY 35159A UY 0001035159 A UY0001035159 A UY 0001035159A UY 35159 A UY35159 A UY 35159A UY 35159 A UY35159 A UY 35159A
- Authority
- UY
- Uruguay
- Prior art keywords
- gen
- biosynthetic
- productivity
- cluster
- improving
- Prior art date
Links
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Método de producción de UK-2 a bajo costo. En el ADN genómico del Streptoverticillium sp. 3-7, que produce UK-2, se identificó una región que es un racimo de genes biosintéticos UK-2. Mediante hibridación, se aisló ADNs en la región, que se usó para preparar una cepa con genes interrumpidos. Se transformó el Streptoverticillium sp. 3-7 mediante un vector que contiene el racimo de genes biosintéticos UK-2 aislados, logrando mejorar su productividad entre 10 y 60 veces o más, en comparación con la de la cepa parenteral. Cada célula de los transformantes poseen 2 copias del racimo de genes biosintéticos de UK-2.UK-2 production method at low cost. In the genomic DNA of Streptoverticillium sp. 3-7, which produces UK-2, a region that is a cluster of UK-2 biosynthetic genes was identified. By hybridization, DNAs were isolated in the region, which was used to prepare a strain with interrupted genes. Streptoverticillium sp. 3-7 using a vector containing the cluster of isolated UK-2 biosynthetic genes, managing to improve their productivity between 10 and 60 times or more, compared to that of the parenteral strain. Each cell of the transformants possess 2 copies of the cluster of biosynthetic genes of UK-2.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
UY0001035159A UY35159A (en) | 2013-11-29 | 2013-11-29 | UK-2 BIOSYNTHETIC GEN AND METHOD FOR IMPROVING THE PRODUCTIVITY OF UK-2 USING SUCH GEN |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
UY0001035159A UY35159A (en) | 2013-11-29 | 2013-11-29 | UK-2 BIOSYNTHETIC GEN AND METHOD FOR IMPROVING THE PRODUCTIVITY OF UK-2 USING SUCH GEN |
Publications (1)
Publication Number | Publication Date |
---|---|
UY35159A true UY35159A (en) | 2015-05-29 |
Family
ID=53491696
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY0001035159A UY35159A (en) | 2013-11-29 | 2013-11-29 | UK-2 BIOSYNTHETIC GEN AND METHOD FOR IMPROVING THE PRODUCTIVITY OF UK-2 USING SUCH GEN |
Country Status (1)
Country | Link |
---|---|
UY (1) | UY35159A (en) |
-
2013
- 2013-11-29 UY UY0001035159A patent/UY35159A/en not_active Application Discontinuation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
104 | Application deemed to be withdrawn (no substantive examination fee paid) |
Effective date: 20201204 |