UY32479A - Procedimiento para la preparación de ramelteon - Google Patents

Procedimiento para la preparación de ramelteon

Info

Publication number
UY32479A
UY32479A UY0001032479A UY32479A UY32479A UY 32479 A UY32479 A UY 32479A UY 0001032479 A UY0001032479 A UY 0001032479A UY 32479 A UY32479 A UY 32479A UY 32479 A UY32479 A UY 32479A
Authority
UY
Uruguay
Prior art keywords
ramelteon
preparation procedure
propionamide
indene
furan
Prior art date
Application number
UY0001032479A
Other languages
English (en)
Inventor
Lenna Roberto
Ghidoli Cristina
Panza Luigi
Original Assignee
Ind Chimica S R L Italian Ltd Liability Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ind Chimica S R L Italian Ltd Liability Company filed Critical Ind Chimica S R L Italian Ltd Liability Company
Publication of UY32479A publication Critical patent/UY32479A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)

Abstract

Se describe un procedimiento para preparar en escala industrial N -[2 - (8S) - 1,6,7,8-tetrahidro - 2H - indeno[5,4 - b]furan - 8 - il]etil]propionamida, ramelteon, que tiene la estructura que se ilustra a continuación:
UY0001032479A 2009-03-10 2010-03-08 Procedimiento para la preparación de ramelteon UY32479A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IT2009/000088 WO2010103553A1 (en) 2009-03-10 2009-03-10 Process for the preparation of ramelteon

Publications (1)

Publication Number Publication Date
UY32479A true UY32479A (es) 2010-08-31

Family

ID=40791226

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001032479A UY32479A (es) 2009-03-10 2010-03-08 Procedimiento para la preparación de ramelteon

Country Status (7)

Country Link
US (1) US8242291B2 (es)
EP (1) EP2406242B1 (es)
JP (1) JP5587350B2 (es)
AR (1) AR075515A1 (es)
CA (1) CA2754802A1 (es)
UY (1) UY32479A (es)
WO (1) WO2010103553A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012035303A2 (en) * 2010-09-17 2012-03-22 Cipla Limited Et Al A novel process for synthesis of ramelteon, and key intermediates for the synthesis of ramelteon
CN103664849B (zh) * 2012-08-31 2017-03-29 上海阳帆医药科技有限公司 制备2‑(1,6,7,8‑四氢‑2H‑茚并[5,4‑b]呋喃‑8‑亚基乙胺的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1199304A1 (en) * 1997-03-05 2002-04-24 Takeda Chemical Industries, Ltd. Bicyclic compounds and pharmaceutical composition containing tricyclic compound for treating or preventing sleep disorders
DE69713294T3 (de) * 1996-03-08 2009-01-15 Takeda Pharmaceutical Co. Ltd. Tricyclische Verbindungen mit Bindungsaffinität für Melatoninrezeptoren, deren Herstellung und Verwendung
TWI400220B (zh) 2004-09-13 2013-07-01 Takeda Pharmaceutical 光活性胺衍生物的製法
WO2009106966A1 (en) * 2008-02-28 2009-09-03 Medichem, S.A. Process for preparing ramelteon.

Also Published As

Publication number Publication date
US20100234622A1 (en) 2010-09-16
JP2012520291A (ja) 2012-09-06
WO2010103553A1 (en) 2010-09-16
JP5587350B2 (ja) 2014-09-10
CA2754802A1 (en) 2010-09-16
EP2406242B1 (en) 2013-06-05
US8242291B2 (en) 2012-08-14
EP2406242A1 (en) 2012-01-18
AR075515A1 (es) 2011-04-06

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Legal Events

Date Code Title Description
104 Application deemed to be withdrawn (no substantive examination fee paid)

Effective date: 20110812