UY30875A1 - Derivados de pirrolopiridina-2-carboxamidas, su preparacion y su aplicacion en terapéutica - Google Patents

Derivados de pirrolopiridina-2-carboxamidas, su preparacion y su aplicacion en terapéutica

Info

Publication number
UY30875A1
UY30875A1 UY30875A UY30875A UY30875A1 UY 30875 A1 UY30875 A1 UY 30875A1 UY 30875 A UY30875 A UY 30875A UY 30875 A UY30875 A UY 30875A UY 30875 A1 UY30875 A1 UY 30875A1
Authority
UY
Uruguay
Prior art keywords
therapeutics
preparation
pirrolopiridina
carboxamidas
derivatives
Prior art date
Application number
UY30875A
Other languages
English (en)
Inventor
Malanda Andre
Yannick Evanno
Laurent Dubois
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of UY30875A1 publication Critical patent/UY30875A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Psychiatry (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La invencion se refiere a compuestos derivados de pirrolopiridina-2-carboxamidas de la formula general (I), en estado de base o de sal de adicion a un ácido, así como en estado de hidrato o de solvato donde los sustituyentes son tales como se han especificado en la memoria descriptiva y en las reivindicaciones. Se divulgan procedimientos de preparacion. Los compuestos presentan una actividad antagonista in vitro e in vivo para los receptores de tipo TRPV1 (o VR1) y son utiles en terapéutica.
UY30875A 2007-01-19 2008-01-18 Derivados de pirrolopiridina-2-carboxamidas, su preparacion y su aplicacion en terapéutica UY30875A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0700356A FR2911605B1 (fr) 2007-01-19 2007-01-19 Derives de pyrrolopyridine-2-carbowamides, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
UY30875A1 true UY30875A1 (es) 2008-09-02

Family

ID=38457983

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30875A UY30875A1 (es) 2007-01-19 2008-01-18 Derivados de pirrolopiridina-2-carboxamidas, su preparacion y su aplicacion en terapéutica

Country Status (18)

Country Link
US (1) US8044066B2 (es)
EP (1) EP2106401B1 (es)
JP (1) JP5264772B2 (es)
AR (1) AR064936A1 (es)
AT (1) ATE549339T1 (es)
CL (1) CL2008000128A1 (es)
CY (1) CY1112855T1 (es)
DK (1) DK2106401T3 (es)
ES (1) ES2384289T3 (es)
FR (1) FR2911605B1 (es)
HR (1) HRP20120496T1 (es)
PE (1) PE20081701A1 (es)
PL (1) PL2106401T3 (es)
PT (1) PT2106401E (es)
SI (1) SI2106401T1 (es)
TW (1) TW200836726A (es)
UY (1) UY30875A1 (es)
WO (1) WO2008107543A2 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2926554B1 (fr) 2008-01-22 2010-03-12 Sanofi Aventis Derives de carboxamides azabicycliques, leur preparation et leur application en therapeutique
FR2926556B1 (fr) * 2008-01-22 2010-02-19 Sanofi Aventis Derives de carboxamides n-azabicycliques, leur preparation et leur application en therapeutique
TWI501967B (zh) * 2010-12-16 2015-10-01 Janssen R&D Ireland 作為呼吸道融合病毒抗病毒劑之氮雜吲哚類
US20210253772A1 (en) 2020-02-18 2021-08-19 Covestro Llc Polyoxazolidinone compositions

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2468544A1 (en) 2001-12-10 2003-06-19 Amgen Inc. Vanilloid receptor ligands
TW200403223A (en) 2002-02-15 2004-03-01 Glaxo Group Ltd Novel compounds
BRPI0410445B1 (pt) 2003-05-21 2017-11-28 Prosidion Limited Pyrrolopyridine-2-carboxylic acid amide inhibitor compound of glycogen phosphorylase, pharmaceutical composition comprising the same, process for its production and intermediate compounds
US7544803B2 (en) * 2004-01-23 2009-06-09 Amgen Inc. Vanilloid receptor ligands and their use in treatments
GB0403819D0 (en) * 2004-02-20 2004-03-24 Merck Sharp & Dohme New compounds
US20090298745A1 (en) 2004-12-02 2009-12-03 Gerard Hugh Thomas Treatment of Diabetes with Glycogen Phosphorylase Inhibitors
CA2598273A1 (en) 2005-02-17 2006-08-24 Merck & Co., Inc. Method of treating atherosclerosis, dyslipidemias and related conditions
FR2888847B1 (fr) * 2005-07-22 2007-08-31 Sanofi Aventis Sa Derives de n-(heteriaryl)-1-heteorarylalkyl-1h-indole-2- carboxamides, leur preparation et application en therapeutique
FR2888848B1 (fr) * 2005-07-22 2007-09-28 Sanofi Aventis Sa Derives de n-(arylalkyl)-1h-pyrrrolopyridine-2-carboxamides, leur preparation et leur application en therapeutique
FR2897061B1 (fr) * 2006-02-03 2010-09-03 Sanofi Aventis Derives de n-heteroaryl-carboxamides tricycliques contenant un motif benzimidazole, leur preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
AR064936A1 (es) 2009-05-06
SI2106401T1 (sl) 2012-07-31
JP2010516661A (ja) 2010-05-20
ES2384289T3 (es) 2012-07-03
US20090298865A1 (en) 2009-12-03
CL2008000128A1 (es) 2008-05-23
WO2008107543A3 (fr) 2008-12-24
CY1112855T1 (el) 2016-02-10
TW200836726A (en) 2008-09-16
PT2106401E (pt) 2012-06-18
FR2911605A1 (fr) 2008-07-25
JP5264772B2 (ja) 2013-08-14
EP2106401B1 (fr) 2012-03-14
ATE549339T1 (de) 2012-03-15
PE20081701A1 (es) 2008-12-31
FR2911605B1 (fr) 2009-04-17
PL2106401T3 (pl) 2012-08-31
US8044066B2 (en) 2011-10-25
WO2008107543A2 (fr) 2008-09-12
EP2106401A2 (fr) 2009-10-07
DK2106401T3 (da) 2012-07-02
HRP20120496T1 (hr) 2012-07-31

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