UY30817A1 - Produccion y uso de variantes no nativas del dominio 2 de bikunina de placenta humana disenada mediante evolucion molecular dirigida - Google Patents

Produccion y uso de variantes no nativas del dominio 2 de bikunina de placenta humana disenada mediante evolucion molecular dirigida

Info

Publication number
UY30817A1
UY30817A1 UY30817A UY30817A UY30817A1 UY 30817 A1 UY30817 A1 UY 30817A1 UY 30817 A UY30817 A UY 30817A UY 30817 A UY30817 A UY 30817A UY 30817 A1 UY30817 A1 UY 30817A1
Authority
UY
Uruguay
Prior art keywords
domain
production
bikunina
designed
human placenta
Prior art date
Application number
UY30817A
Other languages
English (en)
Inventor
Haxel Harrenga
Dr Juergen Franz
Dr Frank Dittmer
Dr Felix Oehme
Dr Heiner Apeler
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39167588&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY30817(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Publication of UY30817A1 publication Critical patent/UY30817A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invencion se refiere a variantes novedosas del dominio 2 de la bikunina de placenta humana con niveles de expresion mejorados y propiedades inhibidoras de la serina proteasa favorables y su produccion y uso .
UY30817A 2006-12-22 2007-12-20 Produccion y uso de variantes no nativas del dominio 2 de bikunina de placenta humana disenada mediante evolucion molecular dirigida UY30817A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06026812 2006-12-22

Publications (1)

Publication Number Publication Date
UY30817A1 true UY30817A1 (es) 2008-07-31

Family

ID=39167588

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30817A UY30817A1 (es) 2006-12-22 2007-12-20 Produccion y uso de variantes no nativas del dominio 2 de bikunina de placenta humana disenada mediante evolucion molecular dirigida

Country Status (6)

Country Link
AR (1) AR064615A1 (es)
CL (1) CL2007003810A1 (es)
PE (1) PE20081847A1 (es)
TW (1) TW200848425A (es)
UY (1) UY30817A1 (es)
WO (1) WO2008086858A1 (es)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19725014A1 (de) * 1997-06-13 1998-12-17 Bayer Ag Aprotininvarianten mit verbesserten Eigenschaften und Bikunine von Aprotininvarianten

Also Published As

Publication number Publication date
CL2007003810A1 (es) 2008-07-18
WO2008086858A1 (en) 2008-07-24
TW200848425A (en) 2008-12-16
AR064615A1 (es) 2009-04-15
PE20081847A1 (es) 2009-01-11

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20170803