UY30679A1 - Derivados hidrazona como inhibidores de quinasa - Google Patents

Derivados hidrazona como inhibidores de quinasa

Info

Publication number
UY30679A1
UY30679A1 UY30679A UY30679A UY30679A1 UY 30679 A1 UY30679 A1 UY 30679A1 UY 30679 A UY30679 A UY 30679A UY 30679 A UY30679 A UY 30679A UY 30679 A1 UY30679 A1 UY 30679A1
Authority
UY
Uruguay
Prior art keywords
hydrazone derivatives
inhibitors
quinasa
quinasa inhibitors
formula
Prior art date
Application number
UY30679A
Other languages
English (en)
Inventor
Gouzhang Xu
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of UY30679A1 publication Critical patent/UY30679A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invencion está dirigida a nuevos compuestos pirimidina bicíclicos de Formula (I) o a una forma o composicion de ésta como inhibidotes de ATP-protein quinasa, donde los sustituyentes en cada lado del enlace doble iminometilo en la Formula (I) puede estar en la configuracion E o Z; y donde R1, R2, R3 y R4 son tal como se definen aquí.
UY30679A 2006-10-31 2007-10-31 Derivados hidrazona como inhibidores de quinasa UY30679A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85572106P 2006-10-31 2006-10-31

Publications (1)

Publication Number Publication Date
UY30679A1 true UY30679A1 (es) 2008-05-02

Family

ID=39344583

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30679A UY30679A1 (es) 2006-10-31 2007-10-31 Derivados hidrazona como inhibidores de quinasa

Country Status (7)

Country Link
US (1) US7893064B2 (es)
AR (1) AR063761A1 (es)
CL (1) CL2007003164A1 (es)
PE (1) PE20081156A1 (es)
TW (1) TW200827350A (es)
UY (1) UY30679A1 (es)
WO (1) WO2008054633A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2287149A1 (en) * 2009-08-20 2011-02-23 Max-Delbrück-Centrum Für Molekulare Medizin Enhancers of protein degradation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9800569D0 (en) * 1998-01-12 1998-03-11 Glaxo Group Ltd Heterocyclic compounds
FR2840898B1 (fr) * 2002-06-14 2004-08-27 Aventis Pharma Sa Derives hydrazide ou hydrazone de l'acide hexahydropyridazine-3-carboxylique, chimiotheques et compositions pharmaceutiques les contenant, utilisation comme medicaments, et procede de preparation

Also Published As

Publication number Publication date
WO2008054633A1 (en) 2008-05-08
TW200827350A (en) 2008-07-01
PE20081156A1 (es) 2008-08-15
CL2007003164A1 (es) 2008-07-11
US20080114004A1 (en) 2008-05-15
US7893064B2 (en) 2011-02-22
AR063761A1 (es) 2009-02-18

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