UY29495A1 - ANTIBODIES AGAINST MYOSTATIN - Google Patents

ANTIBODIES AGAINST MYOSTATIN

Info

Publication number
UY29495A1
UY29495A1 UY29495A UY29495A UY29495A1 UY 29495 A1 UY29495 A1 UY 29495A1 UY 29495 A UY29495 A UY 29495A UY 29495 A UY29495 A UY 29495A UY 29495 A1 UY29495 A1 UY 29495A1
Authority
UY
Uruguay
Prior art keywords
myostatin
antibodies
human
human anti
nucleic acid
Prior art date
Application number
UY29495A
Other languages
Spanish (es)
Inventor
Larry L Green
Eva Rose Chin
Chikwendu Ibebunjo
Philip Albert Krasney
Junming Yie
Joseph Zachwieja
Original Assignee
Pfizer
Amgen Fremont Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer, Amgen Fremont Inc filed Critical Pfizer
Priority to UY29495A priority Critical patent/UY29495A1/en
Publication of UY29495A1 publication Critical patent/UY29495A1/en

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  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La invención se relaciona a anticuerpos humanos y porciones de unión al antígeno de los mismos, que se unen a miostatina para inhibir la miostatina; a anticuerpos anti-miostatina humanos; a anticuerpos que son quiméricos, biespecíficos, derivatizados; a cadenas pesada y liviana aisladas de inmunoglobulinas derivadas de anticuerpos anti-miostatina humanos; y a las moléculas de ácido nucleico que codifican dichas inmunoglobulinas. Se describen métodos para elaborar los anticuerpos anti-miostatina humanos; composiciones que los comprenden; y métodos de diagnóstico y tratamiento. La invención también provee métodos para una terapia génica humana y se relaciona con animales o plantas transgénicas que comprenden las moléculas de ácido nucleico de la presente invención.The invention relates to human antibodies and antigen binding portions thereof, which bind to myostatin to inhibit myostatin; to human anti-myostatin antibodies; to antibodies that are chimeric, bispecific, derivatized; to heavy and light chains isolated from immunoglobulins derived from human anti-myostatin antibodies; and to the nucleic acid molecules encoding said immunoglobulins. Methods for making human anti-myostatin antibodies are described; compositions that comprise them; and diagnostic and treatment methods. The invention also provides methods for human gene therapy and relates to transgenic animals or plants comprising the nucleic acid molecules of the present invention.

UY29495A 2006-04-24 2006-04-24 ANTIBODIES AGAINST MYOSTATIN UY29495A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
UY29495A UY29495A1 (en) 2006-04-24 2006-04-24 ANTIBODIES AGAINST MYOSTATIN

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
UY29495A UY29495A1 (en) 2006-04-24 2006-04-24 ANTIBODIES AGAINST MYOSTATIN

Publications (1)

Publication Number Publication Date
UY29495A1 true UY29495A1 (en) 2006-11-30

Family

ID=38813165

Family Applications (1)

Application Number Title Priority Date Filing Date
UY29495A UY29495A1 (en) 2006-04-24 2006-04-24 ANTIBODIES AGAINST MYOSTATIN

Country Status (1)

Country Link
UY (1) UY29495A1 (en)

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Legal Events

Date Code Title Description
DESI Application deemed to be withdrawn

Effective date: 20120426