UY26908A1 - PROCESS FOR THE MANUFACTURE OF N - ARYL - ANTHRANILIC ACIDS AND THEIR DERIVATIVES - Google Patents
PROCESS FOR THE MANUFACTURE OF N - ARYL - ANTHRANILIC ACIDS AND THEIR DERIVATIVESInfo
- Publication number
- UY26908A1 UY26908A1 UY26908A UY26908A UY26908A1 UY 26908 A1 UY26908 A1 UY 26908A1 UY 26908 A UY26908 A UY 26908A UY 26908 A UY26908 A UY 26908A UY 26908 A1 UY26908 A1 UY 26908A1
- Authority
- UY
- Uruguay
- Prior art keywords
- aryl
- derivatives
- manufacture
- anthranilic acids
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/10—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/04—Formation of amino groups in compounds containing carboxyl groups
- C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
- C07C227/08—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid by reaction of ammonia or amines with acids containing functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Indole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
La presente invención se relaciona con un proceso para la preparación de ácidos N-arilantranílicos, y con un proceso para la preparación de esteres N-antranílicos, amidas, y esteres hidroxamicos.The present invention relates to a process for the preparation of N-arylanthranilic acids, and to a process for the preparation of N-anthranilyl esters, amides, and hydroxamic esters.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22820600P | 2000-08-25 | 2000-08-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY26908A1 true UY26908A1 (en) | 2001-11-30 |
Family
ID=22856235
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY26908A UY26908A1 (en) | 2000-08-25 | 2001-08-24 | PROCESS FOR THE MANUFACTURE OF N - ARYL - ANTHRANILIC ACIDS AND THEIR DERIVATIVES |
Country Status (31)
Country | Link |
---|---|
EP (1) | EP1313694A1 (en) |
JP (1) | JP2004507518A (en) |
KR (1) | KR20030059115A (en) |
CN (1) | CN1458921A (en) |
AP (1) | AP2001002249A0 (en) |
AR (1) | AR032175A1 (en) |
AU (1) | AU2001277044A1 (en) |
BG (1) | BG107635A (en) |
BR (1) | BR0113520A (en) |
CA (1) | CA2420003A1 (en) |
CZ (1) | CZ2003477A3 (en) |
DO (1) | DOP2001000238A (en) |
EA (1) | EA200300187A1 (en) |
GT (1) | GT200100174A (en) |
HN (1) | HN2001000216A (en) |
HU (1) | HUP0300828A2 (en) |
IL (1) | IL154507A0 (en) |
IS (1) | IS6724A (en) |
MA (1) | MA26949A1 (en) |
MX (1) | MXPA03001654A (en) |
NO (1) | NO20030844L (en) |
PA (1) | PA8526501A1 (en) |
PE (1) | PE20020393A1 (en) |
PL (1) | PL360699A1 (en) |
SK (1) | SK2072003A3 (en) |
SV (1) | SV2002000601A (en) |
TN (1) | TNSN01127A1 (en) |
UY (1) | UY26908A1 (en) |
WO (1) | WO2002018319A1 (en) |
YU (1) | YU14303A (en) |
ZA (1) | ZA200301182B (en) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3000810B1 (en) | 2002-03-13 | 2017-07-19 | Array Biopharma, Inc. | N3 alkylated benzimidazole derivative as mek inhibitor |
US7235537B2 (en) | 2002-03-13 | 2007-06-26 | Array Biopharma, Inc. | N3 alkylated benzimidazole derivatives as MEK inhibitors |
US7538120B2 (en) | 2003-09-03 | 2009-05-26 | Array Biopharma Inc. | Method of treating inflammatory diseases |
US7144907B2 (en) | 2003-09-03 | 2006-12-05 | Array Biopharma Inc. | Heterocyclic inhibitors of MEK and methods of use thereof |
RU2352558C2 (en) | 2003-10-21 | 2009-04-20 | Уорнер-Ламберт Компани Ллс | Polymorphic form of n-[(r)-2,3-dihydroxypropoxy]-3,4-difluoro-2-(2-fluoro-4-iodophenylamino)benzamide |
US7598383B2 (en) | 2003-11-19 | 2009-10-06 | Array Biopharma Inc. | Heterocyclic inhibitors of MEK and methods of use thereof |
US7732616B2 (en) | 2003-11-19 | 2010-06-08 | Array Biopharma Inc. | Dihydropyridine and dihydropyridazine derivatives as inhibitors of MEK and methods of use thereof |
US7517994B2 (en) | 2003-11-19 | 2009-04-14 | Array Biopharma Inc. | Heterocyclic inhibitors of MEK and methods of use thereof |
KR101223914B1 (en) | 2003-11-21 | 2013-01-18 | 어레이 바이오파마 인크. | Akt protein kinase inhibitors |
UA89035C2 (en) * | 2003-12-03 | 2009-12-25 | Лео Фарма А/С | Hydroxamic acid esters and pharmaceutical use thereof |
EP1877379B1 (en) | 2005-04-13 | 2013-01-16 | Astex Therapeutics Limited | Hydroxybenzamide derivatives and their use as inhibitors of hsp90 |
CN102942522A (en) | 2005-05-18 | 2013-02-27 | 阵列生物制药公司 | Heterocyclic inhibitors of mek and methods of use thereof |
US7754725B2 (en) | 2006-03-01 | 2010-07-13 | Astex Therapeutics Ltd. | Dihydroxyphenyl isoindolymethanones |
EP2049500B1 (en) | 2006-07-06 | 2011-09-07 | Array Biopharma, Inc. | Cyclopenta [d] pyrimidines as akt protein kinase inhibitors |
WO2008006025A1 (en) | 2006-07-06 | 2008-01-10 | Array Biopharma Inc. | Dihydrofuro pyrimidines as akt protein kinase inhibitors |
JP5231411B2 (en) | 2006-07-06 | 2013-07-10 | アレイ バイオファーマ、インコーポレイテッド | Dihydrothienopyrimidines as AKT protein kinase inhibitors |
US8063050B2 (en) | 2006-07-06 | 2011-11-22 | Array Biopharma Inc. | Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
EP2073807A1 (en) | 2006-10-12 | 2009-07-01 | Astex Therapeutics Limited | Pharmaceutical combinations |
WO2008044027A2 (en) | 2006-10-12 | 2008-04-17 | Astex Therapeutics Limited | Pharmaceutical compounds having hsp90 inhibitory or modulating activity |
GB0620259D0 (en) | 2006-10-12 | 2006-11-22 | Astex Therapeutics Ltd | Pharmaceutical compounds |
EP2073804B1 (en) | 2006-10-12 | 2017-09-13 | Astex Therapeutics Limited | Hydroxy-substituted benzoic acid amide compounds for use in the treatment of pain |
US8916552B2 (en) | 2006-10-12 | 2014-12-23 | Astex Therapeutics Limited | Pharmaceutical combinations |
US8277807B2 (en) | 2006-10-12 | 2012-10-02 | Astex Therapeutics Limited | Pharmaceutical combinations |
US9409886B2 (en) | 2007-07-05 | 2016-08-09 | Array Biopharma Inc. | Pyrimidyl cyclopentanes as AKT protein kinase inhibitors |
SI2173723T1 (en) | 2007-07-05 | 2011-12-30 | Array Biopharma Inc | Pyrimidyl cyclopentanes as akt protein kinase inhibitors |
RU2486181C2 (en) | 2007-07-05 | 2013-06-27 | Эррэй Биофарма Инк. | Pyrimidyl cyclopentanes as akt/protein kinase inhibitors |
US8846683B2 (en) | 2007-07-05 | 2014-09-30 | Array Biopharma, Inc. | Pyrimidyl cyclopentanes as Akt protein kinase inhibitors |
KR101624753B1 (en) | 2008-01-09 | 2016-05-26 | 어레이 바이오파마 인크. | Hydroxylated pyrimidyl cyclopentanes as akt protein kinase inhibitors |
ES2401685T3 (en) | 2008-01-09 | 2013-04-23 | Array Biopharma, Inc. | Hydroxylated pyrimidyl cyclopentane as an AKT protein kinase inhibitor |
GB0806527D0 (en) | 2008-04-11 | 2008-05-14 | Astex Therapeutics Ltd | Pharmaceutical compounds |
CN101985428B (en) * | 2009-07-29 | 2014-02-12 | 杭州民生药业有限公司 | O-anilino benzoic acid derivatives or pharmaceutically acceptable salts thereof as well as preparation method and application thereof |
WO2011101599A1 (en) * | 2010-02-19 | 2011-08-25 | Centre National De La Recherche Scientifique | Method for preparing chemical compounds of interest by aromatic nucleophilic substitution |
CA2789373A1 (en) * | 2010-02-19 | 2011-08-25 | Centre National De La Recherche Scientifique | Process for preparing chemical compounds of interest by nucleophilic aromatic substitution of aromatic carboxylic acid derivatives supporting at least one electro-attractive group |
ES2620644T3 (en) | 2011-04-01 | 2017-06-29 | Genentech, Inc. | Combinations of AKT inhibitor compounds and chemotherapeutic agents, and methods of use |
MX2013011333A (en) | 2011-04-01 | 2014-04-16 | Genentech Inc | Combinations of akt and mek inhibitor compounds, and methods of use. |
MY186549A (en) * | 2012-10-12 | 2021-07-26 | Exelixis Inc | Novel process for making compounds for use in the treatment of cancer |
CN112745237B (en) * | 2019-10-29 | 2023-06-20 | 中国科学院上海药物研究所 | 2-arylamine compound and preparation method and application thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3138636A (en) * | 1960-06-23 | 1964-06-23 | Parke Davis & Co | Anthranilic acid derivatives |
US6251943B1 (en) * | 1997-02-28 | 2001-06-26 | Warner-Lambert Company | Method of treating or preventing septic shock by administering a MEK inhibitor |
CA2290509A1 (en) * | 1997-07-01 | 1999-01-14 | Warner-Lambert Company | 2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as mek inhibitors |
WO1999001426A1 (en) * | 1997-07-01 | 1999-01-14 | Warner-Lambert Company | 4-bromo or 4-iodo phenylamino benzhydroxamic acid derivatives and their use as mek inhibitors |
CA2348236A1 (en) * | 1999-01-13 | 2000-07-20 | Stephen Douglas Barrett | 4-arylamino, 4-aryloxy, and 4-arylthio diarylamines and derivatives thereof as selective mek inhibitors |
KR20010108521A (en) * | 1999-04-21 | 2001-12-07 | 로즈 암스트롱, 크리스틴 에이. 트러트웨인 | Method for Making 2-(N-phenylamino)benzoic Acids |
-
2001
- 2001-07-20 PL PL36069901A patent/PL360699A1/en unknown
- 2001-07-20 WO PCT/US2001/022948 patent/WO2002018319A1/en not_active Application Discontinuation
- 2001-07-20 AP APAP/P/2001/002249A patent/AP2001002249A0/en unknown
- 2001-07-20 EA EA200300187A patent/EA200300187A1/en unknown
- 2001-07-20 HU HU0300828A patent/HUP0300828A2/en unknown
- 2001-07-20 BR BR0113520-1A patent/BR0113520A/en not_active Application Discontinuation
- 2001-07-20 IL IL15450701A patent/IL154507A0/en unknown
- 2001-07-20 KR KR10-2003-7002675A patent/KR20030059115A/en not_active Application Discontinuation
- 2001-07-20 YU YU14303A patent/YU14303A/en unknown
- 2001-07-20 CA CA002420003A patent/CA2420003A1/en not_active Abandoned
- 2001-07-20 CN CN01815869A patent/CN1458921A/en active Pending
- 2001-07-20 MX MXPA03001654A patent/MXPA03001654A/en unknown
- 2001-07-20 EP EP01954824A patent/EP1313694A1/en not_active Withdrawn
- 2001-07-20 CZ CZ2003477A patent/CZ2003477A3/en unknown
- 2001-07-20 SK SK207-2003A patent/SK2072003A3/en unknown
- 2001-07-20 JP JP2002523437A patent/JP2004507518A/en active Pending
- 2001-07-20 AU AU2001277044A patent/AU2001277044A1/en not_active Abandoned
- 2001-08-15 SV SV2001000601A patent/SV2002000601A/en not_active Application Discontinuation
- 2001-08-22 TN TNTNSN01127A patent/TNSN01127A1/en unknown
- 2001-08-23 PA PA20018526501A patent/PA8526501A1/en unknown
- 2001-08-24 AR ARP010104047A patent/AR032175A1/en unknown
- 2001-08-24 UY UY26908A patent/UY26908A1/en not_active Application Discontinuation
- 2001-08-24 GT GT200100174A patent/GT200100174A/en unknown
- 2001-08-24 PE PE2001000853A patent/PE20020393A1/en not_active Application Discontinuation
- 2001-08-24 DO DO2001000238A patent/DOP2001000238A/en unknown
- 2001-09-26 HN HN2001000216A patent/HN2001000216A/en unknown
-
2003
- 2003-02-12 ZA ZA200301182A patent/ZA200301182B/en unknown
- 2003-02-20 IS IS6724A patent/IS6724A/en unknown
- 2003-02-24 NO NO20030844A patent/NO20030844L/en not_active Application Discontinuation
- 2003-03-13 BG BG107635A patent/BG107635A/en unknown
- 2003-03-14 MA MA27069A patent/MA26949A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP1313694A1 (en) | 2003-05-28 |
NO20030844D0 (en) | 2003-02-24 |
ZA200301182B (en) | 2004-05-12 |
CN1458921A (en) | 2003-11-26 |
PL360699A1 (en) | 2004-09-20 |
PA8526501A1 (en) | 2002-07-30 |
SK2072003A3 (en) | 2004-01-08 |
WO2002018319A1 (en) | 2002-03-07 |
EA200300187A1 (en) | 2003-08-28 |
MXPA03001654A (en) | 2004-09-10 |
DOP2001000238A (en) | 2003-01-31 |
CZ2003477A3 (en) | 2003-10-15 |
JP2004507518A (en) | 2004-03-11 |
HN2001000216A (en) | 2002-05-22 |
YU14303A (en) | 2006-08-17 |
SV2002000601A (en) | 2002-04-03 |
GT200100174A (en) | 2002-07-18 |
BR0113520A (en) | 2003-06-24 |
AU2001277044A1 (en) | 2002-03-13 |
PE20020393A1 (en) | 2002-05-09 |
CA2420003A1 (en) | 2002-03-07 |
BG107635A (en) | 2004-09-30 |
MA26949A1 (en) | 2004-12-20 |
IS6724A (en) | 2003-02-20 |
IL154507A0 (en) | 2003-09-17 |
AP2001002249A0 (en) | 2001-09-30 |
NO20030844L (en) | 2003-02-25 |
KR20030059115A (en) | 2003-07-07 |
TNSN01127A1 (en) | 2005-11-10 |
AR032175A1 (en) | 2003-10-29 |
HUP0300828A2 (en) | 2003-09-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
UY26908A1 (en) | PROCESS FOR THE MANUFACTURE OF N - ARYL - ANTHRANILIC ACIDS AND THEIR DERIVATIVES | |
ECSP095220A (en) | DERIVATIVES OF N-FENIL-2-PIRIMIDIN-AMINA | |
HN1999000072A (en) | STABILIZED PHARMACEUTICAL PREPARATIONS FOR GABA PENTINA AND PROCESS FOR PREPARING IT. | |
HN1998000020A (en) | ARILSULFONYL HYDROXAMIC ACID DERIVATIVES. | |
BR0112584A (en) | oxygenated esters of 4-iodophenylamino benzhydroxamic acids | |
BR0115482A (en) | Improved sacralose composition and process for its preparation | |
BR0013885A (en) | Perfected tablets | |
TR200003315T2 (en) | New pharmaceutical composition suitable for emergency use and its preparation method | |
CU22953A3 (en) | PROCEDURE FOR THE PREPARATION OF 8-METOXYCHINOLONCARBOXYLIC ACIDS | |
DE60038560D1 (en) | Process for the fermentative production of L-arginine | |
CY1105526T1 (en) | SYNTHESIS PROCEDURE AND INTERMEDIATES OF PYRIDIN-2-YL-METHYNAMINE | |
JO2249B1 (en) | Synthesis of 3,6-dialkyl-5,6-dihdro-4-hydroxy-2h-pyran-2-one | |
BR0212772A (en) | Process for the preparation of repaglinide | |
BR0212390A (en) | Process for the preparation of cilastatin | |
NO20023276L (en) | Methods of Preparation of Betulinic Acid | |
ATE365036T1 (en) | CREATINESTER PRONUTRIENT COMPOUNDS AND FORMULATIONS | |
EA200100129A1 (en) | METHOD OF OBTAINING HYDROXYMETHYLBYTHEBUTANE ACID | |
AR028078A1 (en) | PROCESS FOR THE PRODUCTION OF ENZYME GRRNULES | |
DE60141311D1 (en) | Process for the production of diaphragms | |
NO20014885D0 (en) | Process for the preparation of an amide compound | |
PT1001929E (en) | PROCESS FOR THE MANUFACTURE OF 3-CYANO-2,4-DIHALOGENE-5-FLUOROBENZOIC ACIDS | |
DE50114758D1 (en) | PROCESS FOR THE PRODUCTION OF INDOLES | |
BRPI0113727B8 (en) | PROCESS FOR THE PRODUCTION OF HALO-4-PHENOXYQUINOLINES. | |
DE50102835D1 (en) | METHOD FOR THE PRODUCTION OF DINITRODIAZAALKANES AND INTERMEDIATE PRODUCTS THEREFOR | |
PT1025081E (en) | S- (4-BIPHENYL) -THESULFURIC ACIDS AND ITS SALTS, PROCESS FOR THE PREPARATION AND PREPARATION OF 4-MERCAPTOBYPHENYLS. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
109 | Application deemed to be withdrawn |
Effective date: 20141001 |