UY26167A1 - Hidroxiamidas de acidos 3 (arilsulfonilamino) tetrahidropiran-3-carboxilicos. - Google Patents
Hidroxiamidas de acidos 3 (arilsulfonilamino) tetrahidropiran-3-carboxilicos.Info
- Publication number
- UY26167A1 UY26167A1 UY26167A UY26167A UY26167A1 UY 26167 A1 UY26167 A1 UY 26167A1 UY 26167 A UY26167 A UY 26167A UY 26167 A UY26167 A UY 26167A UY 26167 A1 UY26167 A1 UY 26167A1
- Authority
- UY
- Uruguay
- Prior art keywords
- hydroxiamides
- tetrahydropiran
- arylsulfonylamine
- carboxylics
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/14—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
Abstract
Un compuesto de fórmula en la que R1, R2, R3 y Q son como se han definido antes, que es útil en el tratamiento de la artritis (incluyendo osteoartritis y artritis reumatoide), el cáncer y otras enfermedades. Además, los compuestos de la presente invención se pueden usar en terapia de combinación con fármacos antiinflamatorios no esteroideos (AiNE), inhibidores de la COX-2 y analgésicos convencionales, y en combinación con fármacos citotóxicos como adriamicina, daunomicina, cisplatino, etopósido, taxol, taxótero y otros alcaloides, como vincristina, en el tratamiento del cáncer.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13653099P | 1999-05-28 | 1999-05-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY26167A1 true UY26167A1 (es) | 2000-12-29 |
Family
ID=22473239
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY26167A UY26167A1 (es) | 1999-05-28 | 2000-05-26 | Hidroxiamidas de acidos 3 (arilsulfonilamino) tetrahidropiran-3-carboxilicos. |
Country Status (22)
Country | Link |
---|---|
US (1) | US6197810B1 (es) |
EP (1) | EP1181286B1 (es) |
JP (1) | JP3784645B2 (es) |
AT (1) | ATE254119T1 (es) |
AU (1) | AU4424000A (es) |
BR (1) | BR0011539A (es) |
CA (1) | CA2375524C (es) |
DE (1) | DE60006523T2 (es) |
DK (1) | DK1181286T3 (es) |
DZ (1) | DZ3046A1 (es) |
ES (1) | ES2208315T3 (es) |
GT (1) | GT200000079A (es) |
HN (1) | HN2000000074A (es) |
MA (1) | MA26738A1 (es) |
MX (1) | MXPA01012265A (es) |
PA (1) | PA8495901A1 (es) |
PE (1) | PE20010170A1 (es) |
PT (1) | PT1181286E (es) |
SV (1) | SV2001000086A (es) |
TN (1) | TNSN00111A1 (es) |
UY (1) | UY26167A1 (es) |
WO (1) | WO2000073295A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040122011A1 (en) * | 1998-12-23 | 2004-06-24 | Pharmacia Corporation | Method of using a COX-2 inhibitor and a TACE inhibitors as a combination therapy |
CZ20023145A3 (cs) | 2000-03-21 | 2003-01-15 | The Procter And Gamble Company | Heterocyklický postranní řetězec obsahující N-substituované inhibitory metaloproteas a farmaceutický přípravek s jejich obsahem |
CA2401728A1 (en) | 2000-03-21 | 2001-09-27 | The Procter & Gamble Company | Difluorobutyric acid metalloprotease inhibitors |
EP1265863A1 (en) * | 2000-03-21 | 2002-12-18 | The Procter & Gamble Company | Heterocyclic side chain containing metalloprotease inhibitors |
US7019376B2 (en) * | 2000-08-11 | 2006-03-28 | Reflectivity, Inc | Micromirror array device with a small pitch size |
US20030045449A1 (en) * | 2001-08-15 | 2003-03-06 | Pfizer, Inc. | Pharmaceutical combinations for the treatment of neurodegenerative diseases |
GB0319069D0 (en) * | 2003-08-14 | 2003-09-17 | Glaxo Group Ltd | Therapeutically useful compounds |
US20050058611A1 (en) * | 2003-08-22 | 2005-03-17 | L'oreal | Preventing and/or combating collagen fiber degradation induced under conditions of natural exposure to sunlight |
RS53941B1 (en) * | 2009-01-12 | 2015-08-31 | Pfizer Limited | SULFONAMID DERIVATIVES |
US9145407B2 (en) | 2010-07-09 | 2015-09-29 | Pfizer Limited | Sulfonamide compounds |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5455258A (en) * | 1993-01-06 | 1995-10-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
DK0977733T3 (da) | 1997-02-03 | 2003-11-24 | Pfizer Prod Inc | Arylsulfonylaminohydroxamsyrederivater |
PA8469501A1 (es) * | 1998-04-10 | 2000-09-29 | Pfizer Prod Inc | Hidroxamidas del acido (4-arilsulfonilamino)-tetrahidropiran-4-carboxilico |
-
2000
- 2000-05-15 CA CA002375524A patent/CA2375524C/en not_active Expired - Fee Related
- 2000-05-15 EP EP00925520A patent/EP1181286B1/en not_active Expired - Lifetime
- 2000-05-15 DE DE60006523T patent/DE60006523T2/de not_active Expired - Fee Related
- 2000-05-15 HN HN2000000074A patent/HN2000000074A/es unknown
- 2000-05-15 MX MXPA01012265A patent/MXPA01012265A/es active IP Right Grant
- 2000-05-15 WO PCT/IB2000/000647 patent/WO2000073295A1/en active IP Right Grant
- 2000-05-15 BR BR0011539-8A patent/BR0011539A/pt not_active IP Right Cessation
- 2000-05-15 AT AT00925520T patent/ATE254119T1/de not_active IP Right Cessation
- 2000-05-15 ES ES00925520T patent/ES2208315T3/es not_active Expired - Lifetime
- 2000-05-15 PT PT00925520T patent/PT1181286E/pt unknown
- 2000-05-15 JP JP2000621361A patent/JP3784645B2/ja not_active Expired - Fee Related
- 2000-05-15 AU AU44240/00A patent/AU4424000A/en not_active Abandoned
- 2000-05-15 DK DK00925520T patent/DK1181286T3/da active
- 2000-05-19 PA PA20008495901A patent/PA8495901A1/es unknown
- 2000-05-24 MA MA25988A patent/MA26738A1/fr unknown
- 2000-05-24 TN TNTNSN00111A patent/TNSN00111A1/fr unknown
- 2000-05-24 DZ DZ000090A patent/DZ3046A1/xx active
- 2000-05-25 GT GT200000079A patent/GT200000079A/es unknown
- 2000-05-26 SV SV2000000086A patent/SV2001000086A/es not_active Application Discontinuation
- 2000-05-26 US US09/579,059 patent/US6197810B1/en not_active Expired - Fee Related
- 2000-05-26 PE PE2000000507A patent/PE20010170A1/es not_active Application Discontinuation
- 2000-05-26 UY UY26167A patent/UY26167A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
PA8495901A1 (es) | 2002-08-26 |
ES2208315T3 (es) | 2004-06-16 |
CA2375524C (en) | 2006-11-28 |
SV2001000086A (es) | 2001-11-08 |
PE20010170A1 (es) | 2001-02-27 |
WO2000073295A1 (en) | 2000-12-07 |
HN2000000074A (es) | 2001-02-02 |
EP1181286B1 (en) | 2003-11-12 |
ATE254119T1 (de) | 2003-11-15 |
BR0011539A (pt) | 2002-02-26 |
DK1181286T3 (da) | 2004-02-16 |
AU4424000A (en) | 2000-12-18 |
JP3784645B2 (ja) | 2006-06-14 |
GT200000079A (es) | 2001-11-16 |
PT1181286E (pt) | 2004-02-27 |
EP1181286A1 (en) | 2002-02-27 |
CA2375524A1 (en) | 2000-12-07 |
DE60006523D1 (de) | 2003-12-18 |
TNSN00111A1 (fr) | 2002-05-30 |
JP2003500485A (ja) | 2003-01-07 |
MXPA01012265A (es) | 2002-07-30 |
US6197810B1 (en) | 2001-03-06 |
DE60006523T2 (de) | 2004-08-12 |
MA26738A1 (fr) | 2004-12-20 |
DZ3046A1 (fr) | 2004-03-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR9912944A (pt) | Inibidores de tace | |
YU5201A (sh) | Derivati hidroksipipekolathidroksamske kiseline kao inhibitori mmp | |
TR200002951T2 (tr) | (4-Arilsülfonilamino)-tetrahidropiran-4-karboksilik asit hidroksamitler | |
MY121754A (en) | Arylsulfonylamino hydroxamic acid derivatives | |
YU37499A (sh) | Derivati arilsulfonil hidroksamske kiseline | |
NO990821L (no) | Arylsulfonylamino-hydroksaminsyre-derivater | |
CA2277100A1 (en) | Cyclic sulfone derivatives | |
CA2260898A1 (en) | Phosphinate based inhibitors of matrix metalloproteases | |
UY26167A1 (es) | Hidroxiamidas de acidos 3 (arilsulfonilamino) tetrahidropiran-3-carboxilicos. | |
UY26169A1 (es) | Hidroxiamidas de ácidos 3-(arilsulfonilamino)- tetrahidrofuran-3-carboxílicos | |
ECSP003494A (es) | Hidroxiamidas de acidos 3- ( arilsulfonilamino)-tetrahidropiran-3-carboxilicos |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
109 | Application deemed to be withdrawn |
Effective date: 20101201 |