USB485972I5 - - Google Patents

Info

Publication number
USB485972I5
USB485972I5 US48597274A USB485972I5 US B485972 I5 USB485972 I5 US B485972I5 US 48597274 A US48597274 A US 48597274A US B485972 I5 USB485972 I5 US B485972I5
Authority
US
United States
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA193,344A external-priority patent/CA1027112A/en
Application filed filed Critical
Priority to US05/485,972 priority Critical patent/US4017472A/en
Publication of USB485972I5 publication Critical patent/USB485972I5/en
Application granted granted Critical
Publication of US4017472A publication Critical patent/US4017472A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60—Two oxygen atoms, e.g. succinic anhydride
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/801—Peptide sweetners

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
US05/485,972 1973-03-05 1974-07-05 Process for isolation of aspartyl dipeptide esters Expired - Lifetime US4017472A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US05/485,972 US4017472A (en) 1973-03-05 1974-07-05 Process for isolation of aspartyl dipeptide esters

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US33792773A 1973-03-05 1973-03-05
CA193344 1974-02-25
CA193,344A CA1027112A (en) 1973-03-05 1974-02-25 Process for isolation of dipeptide esters
US05/485,972 US4017472A (en) 1973-03-05 1974-07-05 Process for isolation of aspartyl dipeptide esters

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US33792773A Continuation-In-Part 1973-03-05 1973-03-05

Publications (2)

Publication Number Publication Date
USB485972I5 true USB485972I5 (it) 1976-03-23
US4017472A US4017472A (en) 1977-04-12

Family

ID=27163325

Family Applications (1)

Application Number Title Priority Date Filing Date
US05/485,972 Expired - Lifetime US4017472A (en) 1973-03-05 1974-07-05 Process for isolation of aspartyl dipeptide esters

Country Status (1)

Country Link
US (1) US4017472A (it)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0128694A2 (en) * 1983-06-08 1984-12-19 Ajinomoto Co., Inc. Method of separating alpha-L-aspartyl-L-phenylalanine methyl ester through crystallization

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5535059A (en) * 1978-09-05 1980-03-11 Ajinomoto Co Inc Preparation of lower alkyl ester of alpha-l-aspartyl-l- phenylalanine
JPS5646850A (en) * 1979-09-27 1981-04-28 Ajinomoto Co Inc Method for reductive elimination of protecting group
FR2516077A1 (fr) * 1981-11-06 1983-05-13 Human Pharm Sa Laboratoires Procede de preparation de l'ester-methylique de l'a-aspartyl phenylalanine
JPS61148198A (ja) * 1984-12-22 1986-07-05 Ajinomoto Co Inc 新規トリペプチド化合物および甘味剤
US4600532A (en) * 1984-12-28 1986-07-15 The Salk Institute Biotechnology/Industrial Associates, Inc. Process and composition for amino-terminal, α-aspartyl and α-glutamyl dipeptides and dipeptide esters
JPH0680074B2 (ja) * 1985-07-01 1994-10-12 味の素株式会社 Ｎ―ホルミル―Ｌ―α―アスパルチル―Ｌ―フェニルアラニンの製法
US5055399A (en) * 1985-01-15 1991-10-08 Genentech, Inc. Enzymatic synthesis of alpha-L-aspartyl-L-phenyalanine lower alkyl esters
JPH11130794A (ja) * 1997-10-23 1999-05-18 Ajinomoto Co Inc アスパルテーム誘導体の精製方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2040473A1 (it) * 1969-04-30 1971-01-22 Ajinomoto Kk
DE2107411A1 (de) * 1970-02-21 1971-08-26 Beecham Group Ltd , Brentford, Middlesex (Großbritannien) Verfahren zur Herstellung von alpha Asparagmylrest enthaltenden Dipeptiden
US3678026A (en) * 1969-12-30 1972-07-18 Ajinomoto Kk Method of purifying lower alkyl esters of {60 -l-aspartyl-l-phenylalanine
US3695898A (en) * 1970-03-25 1972-10-03 Squibb & Sons Inc Sweetening compositions containing saccharin and dipeptides

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2040473A1 (it) * 1969-04-30 1971-01-22 Ajinomoto Kk
US3678026A (en) * 1969-12-30 1972-07-18 Ajinomoto Kk Method of purifying lower alkyl esters of {60 -l-aspartyl-l-phenylalanine
DE2107411A1 (de) * 1970-02-21 1971-08-26 Beecham Group Ltd , Brentford, Middlesex (Großbritannien) Verfahren zur Herstellung von alpha Asparagmylrest enthaltenden Dipeptiden
US3695898A (en) * 1970-03-25 1972-10-03 Squibb & Sons Inc Sweetening compositions containing saccharin and dipeptides

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0128694A2 (en) * 1983-06-08 1984-12-19 Ajinomoto Co., Inc. Method of separating alpha-L-aspartyl-L-phenylalanine methyl ester through crystallization
EP0128694A3 (en) * 1983-06-08 1986-11-26 Ajinomoto Co., Inc. Method of separating alpha-l-aspartyl-l-phenylalanine methyl ester through crystallization

Also Published As

Publication number Publication date
US4017472A (en) 1977-04-12

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Legal Events

Date Code Title Description
AS Assignment

Owner name: NUTRASWEET COMPANY THE

Free format text: CHANGE OF NAME;ASSIGNORS:G. D. SEARLE & CO. (CHANGED TO);NUTRASWEET COMPANY (CHANGED TO);REEL/FRAME:004616/0882

Effective date: 19860519