CA1027112A - Process for isolation of dipeptide esters - Google Patents

Process for isolation of dipeptide esters

Info

Publication number
CA1027112A
CA1027112A CA193,344A CA193344A CA1027112A CA 1027112 A CA1027112 A CA 1027112A CA 193344 A CA193344 A CA 193344A CA 1027112 A CA1027112 A CA 1027112A
Authority
CA
Canada
Prior art keywords
isolation
dipeptide esters
dipeptide
esters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA193,344A
Other languages
French (fr)
Other versions
CA193344S (en
Inventor
Willard M. Hoehn
Joseph F. Zawadzki
Walter G. Farkas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle and Co of Canada Ltd
Original Assignee
GD Searle and Co of Canada Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle and Co of Canada Ltd filed Critical GD Searle and Co of Canada Ltd
Priority to US05/485,972 priority Critical patent/US4017472A/en
Application granted granted Critical
Publication of CA1027112A publication Critical patent/CA1027112A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
CA193,344A 1973-03-05 1974-02-25 Process for isolation of dipeptide esters Expired CA1027112A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US05/485,972 US4017472A (en) 1973-03-05 1974-07-05 Process for isolation of aspartyl dipeptide esters

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33792773A 1973-03-05 1973-03-05

Publications (1)

Publication Number Publication Date
CA1027112A true CA1027112A (en) 1978-02-28

Family

ID=23322619

Family Applications (1)

Application Number Title Priority Date Filing Date
CA193,344A Expired CA1027112A (en) 1973-03-05 1974-02-25 Process for isolation of dipeptide esters

Country Status (5)

Country Link
JP (1) JPS49117445A (en)
CA (1) CA1027112A (en)
CH (1) CH599124A5 (en)
DE (1) DE2410203A1 (en)
GB (1) GB1435481A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5646850A (en) * 1979-09-27 1981-04-28 Ajinomoto Co Inc Method for reductive elimination of protecting group
JPS59227849A (en) * 1983-06-08 1984-12-21 Ajinomoto Co Inc Crystallization and separation of l-alpha-aspartyl-l- phenylalaninemethyl ester
JP2979761B2 (en) * 1991-05-23 1999-11-15 味の素株式会社 Method for producing α-L-aspartyl-L-phenylalanine methyl ester hydrochloride

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5140069B1 (en) * 1971-07-09 1976-11-01

Also Published As

Publication number Publication date
GB1435481A (en) 1976-05-12
CH599124A5 (en) 1978-05-12
DE2410203A1 (en) 1974-09-12
JPS49117445A (en) 1974-11-09

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