US9182398B2 - Methods and compositions for detecting fungi and mycotoxins - Google Patents

Methods and compositions for detecting fungi and mycotoxins Download PDF

Info

Publication number
US9182398B2
US9182398B2 US11/731,674 US73167407A US9182398B2 US 9182398 B2 US9182398 B2 US 9182398B2 US 73167407 A US73167407 A US 73167407A US 9182398 B2 US9182398 B2 US 9182398B2
Authority
US
United States
Prior art keywords
seq
mycotoxin
patient
primer
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active, expires
Application number
US11/731,674
Other languages
English (en)
Other versions
US20080014582A1 (en
Inventor
Dennis G. Hooper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rtl Purchaser LLC
Original Assignee
MEDICAL SERVICE CONSULTATION INTERNATIONAL LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39325071&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=US9182398(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by MEDICAL SERVICE CONSULTATION INTERNATIONAL LLC filed Critical MEDICAL SERVICE CONSULTATION INTERNATIONAL LLC
Priority to US11/731,674 priority Critical patent/US9182398B2/en
Assigned to MEDICAL SERVICE CONSULTATION INTERNATIONAL, LLC reassignment MEDICAL SERVICE CONSULTATION INTERNATIONAL, LLC ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: HOOPER, DENNIS G
Publication of US20080014582A1 publication Critical patent/US20080014582A1/en
Priority to US13/669,579 priority patent/US8628928B2/en
Priority to US13/827,441 priority patent/US20130183697A1/en
Priority to US14/256,269 priority patent/US9103829B2/en
Priority to US14/789,164 priority patent/US20150337396A1/en
Application granted granted Critical
Publication of US9182398B2 publication Critical patent/US9182398B2/en
Priority to US15/144,016 priority patent/US10274493B2/en
Priority to US15/635,807 priority patent/US10036748B2/en
Assigned to ADVATECT DIAGNOSTICS, LLC reassignment ADVATECT DIAGNOSTICS, LLC CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: MEDICAL SERVICE CONSULTATION INTERNATIONAL, L.L.C.
Priority to US16/007,504 priority patent/US20190101534A1/en
Priority to US16/116,032 priority patent/US20190101535A1/en
Priority to US16/361,720 priority patent/US20190277848A1/en
Priority to US18/049,993 priority patent/US20230194523A1/en
Assigned to RTL PURCHASER LLC reassignment RTL PURCHASER LLC ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ADVATECT DIAGNOSTICS, LLC
Active legal-status Critical Current
Adjusted expiration legal-status Critical

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56961—Plant cells or fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/142—Toxicological screening, e.g. expression profiles which identify toxicity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/10—Detection of antigens from microorganism in sample from host
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/26—Infectious diseases, e.g. generalised sepsis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Botany (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
US11/731,674 2006-04-01 2007-03-30 Methods and compositions for detecting fungi and mycotoxins Active 2028-11-20 US9182398B2 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
US11/731,674 US9182398B2 (en) 2006-04-01 2007-03-30 Methods and compositions for detecting fungi and mycotoxins
US13/669,579 US8628928B2 (en) 2006-04-01 2012-11-06 Methods and compositions for detecting fungi and mycotoxins
US13/827,441 US20130183697A1 (en) 2006-04-01 2013-03-14 Methods And Compositions For Detecting Fungi And Mycotoxins
US14/256,269 US9103829B2 (en) 2006-04-01 2014-04-18 Methods and compositions for detecting fungi and mycotoxins
US14/789,164 US20150337396A1 (en) 2006-04-01 2015-07-01 Method and compositions for detecting fungi and mycotoxins
US15/144,016 US10274493B2 (en) 2006-04-01 2016-05-02 Methods and compositions for detecting fungi and mycotoxins
US15/635,807 US10036748B2 (en) 2006-04-01 2017-06-28 Methods and compositions for detecting fungi and mycotoxins
US16/007,504 US20190101534A1 (en) 2006-04-01 2018-06-13 Methods and compositions for detecting fungi and mycotoxins
US16/116,032 US20190101535A1 (en) 2006-04-01 2018-08-29 Methods and compositions for detecting fungi and mycotoxins
US16/361,720 US20190277848A1 (en) 2006-04-01 2019-03-22 Methods and compositions for detecting fungi and mycotoxins
US18/049,993 US20230194523A1 (en) 2006-04-01 2022-10-26 Methods and compositions for detecting fungi and mycotoxins

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78775406P 2006-04-01 2006-04-01
US79097406P 2006-04-11 2006-04-11
US11/731,674 US9182398B2 (en) 2006-04-01 2007-03-30 Methods and compositions for detecting fungi and mycotoxins

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US13/669,579 Continuation US8628928B2 (en) 2006-04-01 2012-11-06 Methods and compositions for detecting fungi and mycotoxins

Publications (2)

Publication Number Publication Date
US20080014582A1 US20080014582A1 (en) 2008-01-17
US9182398B2 true US9182398B2 (en) 2015-11-10

Family

ID=39325071

Family Applications (11)

Application Number Title Priority Date Filing Date
US11/731,674 Active 2028-11-20 US9182398B2 (en) 2006-04-01 2007-03-30 Methods and compositions for detecting fungi and mycotoxins
US13/669,579 Active US8628928B2 (en) 2006-04-01 2012-11-06 Methods and compositions for detecting fungi and mycotoxins
US13/827,441 Abandoned US20130183697A1 (en) 2006-04-01 2013-03-14 Methods And Compositions For Detecting Fungi And Mycotoxins
US14/256,269 Active US9103829B2 (en) 2006-04-01 2014-04-18 Methods and compositions for detecting fungi and mycotoxins
US14/789,164 Abandoned US20150337396A1 (en) 2006-04-01 2015-07-01 Method and compositions for detecting fungi and mycotoxins
US15/144,016 Active US10274493B2 (en) 2006-04-01 2016-05-02 Methods and compositions for detecting fungi and mycotoxins
US15/635,807 Active US10036748B2 (en) 2006-04-01 2017-06-28 Methods and compositions for detecting fungi and mycotoxins
US16/007,504 Abandoned US20190101534A1 (en) 2006-04-01 2018-06-13 Methods and compositions for detecting fungi and mycotoxins
US16/116,032 Abandoned US20190101535A1 (en) 2006-04-01 2018-08-29 Methods and compositions for detecting fungi and mycotoxins
US16/361,720 Abandoned US20190277848A1 (en) 2006-04-01 2019-03-22 Methods and compositions for detecting fungi and mycotoxins
US18/049,993 Pending US20230194523A1 (en) 2006-04-01 2022-10-26 Methods and compositions for detecting fungi and mycotoxins

Family Applications After (10)

Application Number Title Priority Date Filing Date
US13/669,579 Active US8628928B2 (en) 2006-04-01 2012-11-06 Methods and compositions for detecting fungi and mycotoxins
US13/827,441 Abandoned US20130183697A1 (en) 2006-04-01 2013-03-14 Methods And Compositions For Detecting Fungi And Mycotoxins
US14/256,269 Active US9103829B2 (en) 2006-04-01 2014-04-18 Methods and compositions for detecting fungi and mycotoxins
US14/789,164 Abandoned US20150337396A1 (en) 2006-04-01 2015-07-01 Method and compositions for detecting fungi and mycotoxins
US15/144,016 Active US10274493B2 (en) 2006-04-01 2016-05-02 Methods and compositions for detecting fungi and mycotoxins
US15/635,807 Active US10036748B2 (en) 2006-04-01 2017-06-28 Methods and compositions for detecting fungi and mycotoxins
US16/007,504 Abandoned US20190101534A1 (en) 2006-04-01 2018-06-13 Methods and compositions for detecting fungi and mycotoxins
US16/116,032 Abandoned US20190101535A1 (en) 2006-04-01 2018-08-29 Methods and compositions for detecting fungi and mycotoxins
US16/361,720 Abandoned US20190277848A1 (en) 2006-04-01 2019-03-22 Methods and compositions for detecting fungi and mycotoxins
US18/049,993 Pending US20230194523A1 (en) 2006-04-01 2022-10-26 Methods and compositions for detecting fungi and mycotoxins

Country Status (2)

Country Link
US (11) US9182398B2 (fr)
WO (1) WO2008051285A2 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10030278B2 (en) 2008-08-22 2018-07-24 Advatect Diagnostics, Llc Methods and compositions for identifying yeast
US10036748B2 (en) 2006-04-01 2018-07-31 Advatect Diagnostics, Llc Methods and compositions for detecting fungi and mycotoxins
US10443106B2 (en) 2009-10-08 2019-10-15 Advatect Diagnostics, Llc Methods and compositions for identifying sulfur and iron modifying bacteria

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100075322A1 (en) * 2008-08-22 2010-03-25 Hooper Dennis G Methods and Compositions for Identifying Mycotoxins and Fungal Species
EP2465945A1 (fr) * 2010-12-17 2012-06-20 F. Hoffmann-La Roche AG Matrice générique pour acides nucléiques de contrôle
ITMO20110109A1 (it) * 2011-05-11 2012-11-12 Generon S R L Metodo per l'analisi di aflatossine nel latte e nei derivati del latte
US8956821B2 (en) 2013-02-06 2015-02-17 Medical Service Consultation International, Llc Methods and compositions for detecting Aspergillus terreus, Aspergillus niger, and mycotoxins
US9658136B2 (en) * 2014-04-18 2017-05-23 Sue Price Mycotoxin sample-collecting kit and method
EP3257951A3 (fr) 2016-06-17 2018-03-14 AdvaTect Diagnostics, LLC Procédés et compositions pour identifier et quantifier l'adn fongique
US20210293813A1 (en) * 2020-03-18 2021-09-23 Waters Technologies Corporation High throughput affinity sample preparation for mycotoxin analysis
CN113293225B (zh) * 2021-06-29 2024-04-02 江南大学 一种能特异性识别曲霉属、青霉属和镰刀菌属的引物探针组合及其应用
CN113684303A (zh) * 2021-09-09 2021-11-23 三只松鼠股份有限公司 一种用于检测坚果中霉菌的引物组合、试剂盒及坚果中产霉菌毒素真菌种类的检测方法
CN117568509A (zh) * 2023-11-17 2024-02-20 厦门飞朔生物技术有限公司 一种基于微滴数字pcr技术检测曲霉、青霉和镰刀菌的引物探针组合及应用

Citations (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4744981A (en) 1985-10-17 1988-05-17 Neorx Corporation Trichothecene antibody conjugates
US4772551A (en) 1985-12-26 1988-09-20 Neogen Corporation Method and test kit for detecting a trichothecene using novel monoclonal antibodies
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US5261394A (en) 1991-09-30 1993-11-16 Triangle Research And Development Corporation Percussive aid for the treatment of chronic lung disease
US5426027A (en) 1993-05-20 1995-06-20 The Government Of The United States Of America As Represented By The Secretary Nucleic acid probes and methods for detecting Candida DNA cells in blood
WO1996021741A1 (fr) 1995-01-13 1996-07-18 Chiron Diagnostics Corporation Sondes d'acide nucleique pour la detection et l'identification de champignons
US5776694A (en) 1990-10-19 1998-07-07 Becton Dickinson Company Diagnostic kits useful for selectively detecting microorganisms in samples
WO1998050584A2 (fr) 1997-05-02 1998-11-12 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, c/o Centers for Disease Control and Prevention, Technology Transfer Offic Acides nucleiques pour la detection du genre aspergillus et autres champignons filamenteux
US6210345B1 (en) 1999-10-04 2001-04-03 American Biosystems, Inc. Outcome measuring airway resistance diagnostic system
US20010004813A1 (en) 1999-05-28 2001-06-28 Hedman David E. System and method for removing harmful organic substances from an enclosure
US6268222B1 (en) 1998-01-22 2001-07-31 Luminex Corporation Microparticles attached to nanoparticles labeled with flourescent dye
WO2001054653A1 (fr) 2000-01-28 2001-08-02 Merck Patent Gmbh Formulation galenique
US6345025B1 (en) 1993-04-12 2002-02-05 Olympus Optical Co., Ltd. Apparatus for recording and/or reproducing information and/or from optical information record disk
US6362008B1 (en) 1997-12-23 2002-03-26 Barbara A. Kohn Generic signalling mechanism for detection of analytes
EP1215282A1 (fr) * 1999-09-07 2002-06-19 Kyowa Medex Co., Ltd. Procede de detection de mycotoxines de trichothecene et leur reactif
US20030054356A1 (en) 2000-09-21 2003-03-20 Jacobson James W. Multiple reporter read-out for bioassays
US20030203412A1 (en) * 2002-04-26 2003-10-30 Aristo Vojdani Immunoassay for detection of antibodies for molds and mycotoxins
US20040023207A1 (en) 2002-07-31 2004-02-05 Hanan Polansky Assays for drug discovery based on microcompetition with a foreign polynucleotide
US6696304B1 (en) * 1999-02-24 2004-02-24 Luminex Corporation Particulate solid phase immobilized protein quantitation
US6699670B2 (en) 2001-03-01 2004-03-02 The Johns Hopkins University Quantitative assay for the simultaneous detection and speciation of bacterial infections
WO2004054359A2 (fr) 2002-12-13 2004-07-01 A.M.C. Chemical S.L. Biopesticide et formulations
US20040170981A1 (en) 2003-02-10 2004-09-02 Mckenney Keith Real-time polymerase chain reaction using large target amplicons
US6846631B2 (en) 2001-09-24 2005-01-25 Syngenta Participations Ag Detection of Fusarium species infecting corn using the polymerase chain reaction
US6872523B1 (en) 2000-05-30 2005-03-29 The Board Of Regents Of The University Of Nebraska Materials and methods for molecular detection of clinically relevant pathogenic fungal species
US20050176023A1 (en) 2003-08-01 2005-08-11 Dynal Biotech Inc. Self-hybridizing multiple target nucleic acid probes and methods of use
WO2007023461A2 (fr) 2005-08-26 2007-03-01 Philips Intellectual Property & Standards Gmbh Methode de detection de micro-organismes et de marqueurs de resistance aux antibiotiques et oligonucléotides d'acides nucleiques a cet effet
US20080014582A1 (en) 2006-04-01 2008-01-17 Hooper Dennis G Methods and compositions for detecting fungi and mycotoxins
US20080108905A1 (en) 2002-09-20 2008-05-08 Cprx, Llc System for sensing, diagnosing and treating physiological conditions and methods
US7384622B2 (en) 2004-08-31 2008-06-10 National Institute Of Advanced Industrial Science And Technology Zeolite nano-crystal suspension, zeolite nano-crystal production method, zeolite nano-crystal suspension production method, and zeolite thin film
US20100068718A1 (en) 2008-08-22 2010-03-18 Hooper Dennis G Methods and Compositions for Identifying Yeast
US20100075322A1 (en) 2008-08-22 2010-03-25 Hooper Dennis G Methods and Compositions for Identifying Mycotoxins and Fungal Species
US20100129821A1 (en) 2008-11-26 2010-05-27 Fred Hutchinson Cancer Research Center Broad range pcr-based compositions and methods for the detection and identification of fungal pathogens
US20110104684A1 (en) 2009-10-08 2011-05-05 Hooper Dennis G Methods and Compositions for Identifying Sulfur and Iron Modifying Bacteria
US20140221504A1 (en) 2013-02-06 2014-08-07 Medical Service Consultation International Llc Methods And Compositions For Detecting Aspergillus Terreus, Aspergillus Niger, And Mycotoxins

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3940598A1 (de) 1989-12-08 1991-06-13 Behringwerke Ag Toxoplasma gondii-antigene, ihre herstellung und ihre verwendung
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4835100A (en) * 1986-10-31 1989-05-30 Neogen Corporation Method and test kit for detecting an aflatoxin B1 and G1 using novel monoclonal antibodies
CA2172963C (fr) 1993-09-29 2007-09-11 Reuben Matalon Gene de l'aspartoacylase, proteine, et procedes de depistage de mutations associees a la maladie de canavan
US5922855A (en) 1993-12-17 1999-07-13 Oregon Health Sciences University Mammalian DNA mismatch repair genes MLH1 and PMS1
US5707802A (en) 1995-01-13 1998-01-13 Ciba Corning Diagnostics Corp. Nucleic acid probes for the detection and identification of fungi
US6218529B1 (en) 1995-07-31 2001-04-17 Urocor, Inc. Biomarkers and targets for diagnosis, prognosis and management of prostate, breast and bladder cancer
DE69737125T3 (de) 1996-10-31 2015-02-26 Human Genome Sciences, Inc. Streptococcus pneumoniae-Antigene und Impfstoffe
WO1999020752A1 (fr) 1997-10-21 1999-04-29 The University Court Of The University Of Glasgow JMY QUI EST UN COACTIVATEUR DE p300/CBP, ACIDE NUCLEIQUE CODANT JMY ET LEURS UTILISATIONS
US20040166492A1 (en) 2002-02-05 2004-08-26 Engel Stacia R. Quantitative detection of dekkera and saccharomyces
DE60333035D1 (de) 2002-12-23 2010-07-29 Vical Inc Impfstoffe gegen infektionen mit dem humanen zytomegalivirus auf grundlage von codonoptimierten polynukleotiden
US20050233314A1 (en) 2003-06-30 2005-10-20 National Health Research Institutes Sensitive and quantitative detection of pathogens by real-time nested PCR
PE20060789A1 (es) 2004-10-22 2006-08-10 Biosigma Sa Cepa de bacteria wenelen dsm 16786 y proceso de lixiviacion basado en la inoculacion de dicha cepa
US8497113B2 (en) 2006-02-06 2013-07-30 Jx Nippon Mining & Metals Corporation Chloride ion-resistant sulfur-oxidizing bacteria
JP5077984B2 (ja) 2006-06-29 2012-11-21 独立行政法人産業技術総合研究所 穀類又はナッツ類の流通過程におけるマイコトキシン汚染を予測する方法
CZ302670B6 (cs) 2009-04-21 2011-08-24 Masarykova Univerzita Zpusob diagnostiky invazivní aspergilózy a oligonukleotidy pro použití pri tomto zpusobu
MY153040A (en) 2009-08-27 2014-12-31 Alltech Inc Synthetic mycotoxin adsorbents and methods of making and utilizing the same
WO2014197607A1 (fr) 2013-06-05 2014-12-11 The Regents Of The University Of California Détection de maladies transmises par les tiques
IL227374B (en) 2013-07-08 2018-11-29 Michael Schlosser Aids for providing acupuncture treatment and other healing procedures
CA2998873A1 (fr) 2015-09-17 2017-03-23 Advatect Diagnostics, Llc Procedes et compositions pour detecter des mycotoxines

Patent Citations (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4906452A (en) 1985-10-17 1990-03-06 Neorx Corporation Trichothecene conjugates and methods of use
US4744981A (en) 1985-10-17 1988-05-17 Neorx Corporation Trichothecene antibody conjugates
US4772551A (en) 1985-12-26 1988-09-20 Neogen Corporation Method and test kit for detecting a trichothecene using novel monoclonal antibodies
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US5776694A (en) 1990-10-19 1998-07-07 Becton Dickinson Company Diagnostic kits useful for selectively detecting microorganisms in samples
US5261394A (en) 1991-09-30 1993-11-16 Triangle Research And Development Corporation Percussive aid for the treatment of chronic lung disease
US6345025B1 (en) 1993-04-12 2002-02-05 Olympus Optical Co., Ltd. Apparatus for recording and/or reproducing information and/or from optical information record disk
US5426027A (en) 1993-05-20 1995-06-20 The Government Of The United States Of America As Represented By The Secretary Nucleic acid probes and methods for detecting Candida DNA cells in blood
WO1996021741A1 (fr) 1995-01-13 1996-07-18 Chiron Diagnostics Corporation Sondes d'acide nucleique pour la detection et l'identification de champignons
US6372430B1 (en) 1997-05-02 2002-04-16 The United States Of America As Represented By The Department Of Health And Human Services Nucleic acids for detecting Aspergillus species and other filamentous fungi
US20030129600A1 (en) 1997-05-02 2003-07-10 Dept. Of Health & Human Ser., C/O Ctr. For Disease Control & Prevention, Ofc. Of Technology Transfer Nucleic acids for detecting Aspergillus species and other filamentous fungi
WO1998050584A2 (fr) 1997-05-02 1998-11-12 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, c/o Centers for Disease Control and Prevention, Technology Transfer Offic Acides nucleiques pour la detection du genre aspergillus et autres champignons filamenteux
US6362008B1 (en) 1997-12-23 2002-03-26 Barbara A. Kohn Generic signalling mechanism for detection of analytes
US6268222B1 (en) 1998-01-22 2001-07-31 Luminex Corporation Microparticles attached to nanoparticles labeled with flourescent dye
US6696304B1 (en) * 1999-02-24 2004-02-24 Luminex Corporation Particulate solid phase immobilized protein quantitation
US20010004813A1 (en) 1999-05-28 2001-06-28 Hedman David E. System and method for removing harmful organic substances from an enclosure
EP1215282A1 (fr) * 1999-09-07 2002-06-19 Kyowa Medex Co., Ltd. Procede de detection de mycotoxines de trichothecene et leur reactif
US6210345B1 (en) 1999-10-04 2001-04-03 American Biosystems, Inc. Outcome measuring airway resistance diagnostic system
WO2001054653A1 (fr) 2000-01-28 2001-08-02 Merck Patent Gmbh Formulation galenique
US6872523B1 (en) 2000-05-30 2005-03-29 The Board Of Regents Of The University Of Nebraska Materials and methods for molecular detection of clinically relevant pathogenic fungal species
US20030054356A1 (en) 2000-09-21 2003-03-20 Jacobson James W. Multiple reporter read-out for bioassays
US6699670B2 (en) 2001-03-01 2004-03-02 The Johns Hopkins University Quantitative assay for the simultaneous detection and speciation of bacterial infections
US6846631B2 (en) 2001-09-24 2005-01-25 Syngenta Participations Ag Detection of Fusarium species infecting corn using the polymerase chain reaction
US20030203412A1 (en) * 2002-04-26 2003-10-30 Aristo Vojdani Immunoassay for detection of antibodies for molds and mycotoxins
US20040023207A1 (en) 2002-07-31 2004-02-05 Hanan Polansky Assays for drug discovery based on microcompetition with a foreign polynucleotide
US20080108905A1 (en) 2002-09-20 2008-05-08 Cprx, Llc System for sensing, diagnosing and treating physiological conditions and methods
WO2004054359A2 (fr) 2002-12-13 2004-07-01 A.M.C. Chemical S.L. Biopesticide et formulations
US20040170981A1 (en) 2003-02-10 2004-09-02 Mckenney Keith Real-time polymerase chain reaction using large target amplicons
US20050176023A1 (en) 2003-08-01 2005-08-11 Dynal Biotech Inc. Self-hybridizing multiple target nucleic acid probes and methods of use
US7384622B2 (en) 2004-08-31 2008-06-10 National Institute Of Advanced Industrial Science And Technology Zeolite nano-crystal suspension, zeolite nano-crystal production method, zeolite nano-crystal suspension production method, and zeolite thin film
WO2007023461A2 (fr) 2005-08-26 2007-03-01 Philips Intellectual Property & Standards Gmbh Methode de detection de micro-organismes et de marqueurs de resistance aux antibiotiques et oligonucléotides d'acides nucleiques a cet effet
US20130059307A1 (en) 2006-04-01 2013-03-07 Medical Service Consultation International, Llc Methods And Compositions For Detecting Fungi And Mycotoxins
US20080014582A1 (en) 2006-04-01 2008-01-17 Hooper Dennis G Methods and compositions for detecting fungi and mycotoxins
WO2008051285A2 (fr) 2006-04-01 2008-05-02 Medical Service Consultation International, Llc Procédés et compositions de détection de champignons et de mycotoxines
US20140342927A1 (en) 2006-04-01 2014-11-20 Medical Service Consultation International Llc Methods and compositions for detecting fungi and mycotoxins
US8628928B2 (en) 2006-04-01 2014-01-14 Medical Service Consultation International, Llc Methods and compositions for detecting fungi and mycotoxins
US20130183697A1 (en) 2006-04-01 2013-07-18 Medical Service Consultation International Llc Methods And Compositions For Detecting Fungi And Mycotoxins
US20100068718A1 (en) 2008-08-22 2010-03-18 Hooper Dennis G Methods and Compositions for Identifying Yeast
US20100075322A1 (en) 2008-08-22 2010-03-25 Hooper Dennis G Methods and Compositions for Identifying Mycotoxins and Fungal Species
US20100129821A1 (en) 2008-11-26 2010-05-27 Fred Hutchinson Cancer Research Center Broad range pcr-based compositions and methods for the detection and identification of fungal pathogens
US20110104684A1 (en) 2009-10-08 2011-05-05 Hooper Dennis G Methods and Compositions for Identifying Sulfur and Iron Modifying Bacteria
US8962251B2 (en) 2009-10-08 2015-02-24 Medical Service Consultation International, Llc Methods and compositions for identifying sulfur and iron modifying bacteria
US20140221504A1 (en) 2013-02-06 2014-08-07 Medical Service Consultation International Llc Methods And Compositions For Detecting Aspergillus Terreus, Aspergillus Niger, And Mycotoxins
US8956821B2 (en) 2013-02-06 2015-02-17 Medical Service Consultation International, Llc Methods and compositions for detecting Aspergillus terreus, Aspergillus niger, and mycotoxins

Non-Patent Citations (48)

* Cited by examiner, † Cited by third party
Title
Ahern, The Scientist, 1995; 20(15):1-9.
Andersson et al., Appl Environ Microbiol, 1997, 63(2): 387-393.
Bata et al., Appl Environ Microbiol, Mar. 1985, 49(3): 678-681.
Bennett et al., "Mycotoxins," Clin. Microbiol. Rev., 2003; 16(3):497-516.
Bialek et al., "PCR based identification and discrimination of agents of mucomycosis and aspergillosis in paraffin wax embedded tissue," J. Clin. Pathol., 2005; 58:1180-1184.
Brasel at el., Archives of Environmental Health: An international Journal, Jun. 2004, 59(6): 317-323.
Brasel et al, "Detection of airborne Stachybotrys chartarum macrocyclic trichothecene mycotoxins on particulates smaller than conidia," Applied and Environmental Microbiology, 2005; 71:114-122.
Brasel et al., (Archives of Environmental Health: An International Journal. Jun. 2004. vol. 59(6):317-323). *
Brasilerio et al., "Genetic variability within Fusarium solani specie as revealed by PCR-fingerprinting based on pcr markers," Brazilian Journal of Microbiology, 2004, 35: 205-210.
Chen et al., Identification of Medically Important Yeasts Using PCR-Based Detection of DNA Sequence Polymorphisms in the Internal Transcribed Spacer 2 Region of the rRNA Genes, Journal of Clinical Microbiology, Jun. 2000, p. 2302-2310 (9 pages).
Cruz-Perez et al., Detection and quantitation of Aspergillus fumigatus in pure culture using polymerase chain reaction, Molecular and Cellular Probes, 2001; 15:81-88.
De Aguirre et al., Journal of Clinical Microbiology, 2004, 42(8): 3495-3504.
De Vries et al. "Aspergillus vadensis, a new species of the group of black Aspergilli," Antoine Van Leeuwenhoek, 2005; 87(3): 195-203.
Ferns, "Evaluation of the role of real-time PCR in the diagnosis of invasive aspergillosis," Leukemia & Lymphoma, 2006; 41(1): 15-20.
Fontelo et al., (Applied and Environmental Microbio. 1983. vol. 45(2): 640-643). *
Fox et al., "Detection of Aspergillus fumigatus mycotoxins: immunogen synthesis and immunoassay development," Journal of Microbiological Methods, 2004; 6+: 221-230.
GenBank AF 138287 [online] Apr. 11, 2000 [retrieved Sep. 20, 2014] retrieved from http://www.ncbi.nlm.nih.gov/nuccore/af138287.
GenBank AF138288 [online] Apr. 11, 2000 [retrieved on Feb. 23, 2012] retrieved from http://www.ncbi.nlm.nih.gov/nuccore/af138288.
Gregory et al., Toxicology Pathol., 2004, 32: 26-34.
Groopman et al., (P.N.A.S. 1984. vol. 81, pp. 7728-7731). *
Haugland et al., "Identification of putative sequence specific PCR primers for detection of the toxigenic fungal species Stachybotrys chartarum," Mol Cell Probes, Dec. 1998, 12(6): 387-96.
Henry et al., Identification of Aspergillus Species Using Internal Transcribed Spacer Regions 1 and 2, Journal of Clinical Microbiology, Apr. 2000, p. 1510-1515 (6 pages).
Hinrikson et al., Journal of Clinical Microbiology, 2005, 43(5): 2092-2103.
International Search Report and the Written Opinion of the International Searching Authority dated Oct. 17, 2008 filed in related International Application No. PCT/US07/0824921, filed Mar. 30, 2007 (21 pages).
Kierek-Jaszcuk et al., (Food and Agricultural Immunology. 1995. vol. 7(3):243-252). *
Koster et al., A Geographically Diverse Set of Isolates Indicates Two Phylogenetic Lineages Within Strachybotrys Chartarum, Can. J. Bot. 81: 633-643, 2003 (10 pages).
Lee et al., (J. Assoc. Off. Anal. Chem. vol. 1989. 72. No. 2: 345-348). *
Lee et al., J. Agric. Food Chem., 1990, 38: 444-448.
Lewis et al., "Detection of gliotoxin in experimental and human aspergillosis," Infection and Immunity; 2005; 73(1): 635-637.
Llobet-Brossa et al., Aquatic Microbial Ecol, 2002, 29: 211-226.
Mackay et al., "Real-time PCR in the microbiology laboratory," Clin. Microbiol. Infect, 2004, 10: 190-212.
McCormick et al., Toxins, 2011, 3: 802-814.
Nielsen et al., "Yeast populations associated with Ghanaian cocoa fermentations analyzed using denaturing gradient gel electrophoresis (DGGE)," Yeast; 2005; 22:271-284.
Niesters, et al., Rapid, Polymerase Chain Reaction-Based Identification Assays for Candida Species, Journal of Clinical Microbiology, Apr. 1993, p. 904-910 (7 pages).
QuantiTox Kit from EviroLogix (Jul. 12, 2004).
Quatrini et al., Hydrometallurgy, 2006, 83: 263-272.
Spiess et al., "Development of a LightCycler PCR assay for detection and qualification of Aspergillus fumigatus DNA in clinical samples from neutropenic patients," Journal of Clinical Microbiology, 2003; 41(5): 1811-1818.
Stack et al., "Nonribosomal peptide synthesis in Apergillus fumigates and other fungi," Microbiology, 2007; 153(5): 1297-1306.
Suga et al., "Phylogenetic analysis of the phytopathogenic fungus Fusarium solani cased on the rDNA-ITS region," Mycological Research, 2000, 104(10): 1175-1183.
U.S. Appl. No. 14/590,151, unpublished.
U.S. Appl. No. 14/590,173, unpublished.
Vetro (PhD. Thesis: Development of sensitive immunodiagnostics for determination of toxic residues (mycotoxins, drugs) in biological fluids and animal feeds. 2002). *
Wei et al., Anal Biochem., Feb. 1987, 160(2): 399-408.
Willinger et al., Journal of Clinical Microbiology, 2003, 41(2): 581-585.
Wulf-Durand et al., Appl. Environ. Microbiol., 1997, 63(7): 2944-2948.
Yamanaka, Biochemistry and Environmental Biology: Chemolitho-autotrophic Bacteria, 2008, pp. 7-9.
Zinkevich et al., FEMS Microbiology Ecology, 2000, 34: 147-155.
Zorgani et al,., "Detection pyrogenic toxin of Staphylococcus aureus in sudden infant death syndrome," FEMS Immunology and Medical Microbiology, 1999; 25: 103-108.

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10036748B2 (en) 2006-04-01 2018-07-31 Advatect Diagnostics, Llc Methods and compositions for detecting fungi and mycotoxins
US10274493B2 (en) 2006-04-01 2019-04-30 Advatect Diagnostics, Llc Methods and compositions for detecting fungi and mycotoxins
US10030278B2 (en) 2008-08-22 2018-07-24 Advatect Diagnostics, Llc Methods and compositions for identifying yeast
US10793920B2 (en) 2008-08-22 2020-10-06 Mycodart, Inc. Methods and compositions for identifying yeast
US10443106B2 (en) 2009-10-08 2019-10-15 Advatect Diagnostics, Llc Methods and compositions for identifying sulfur and iron modifying bacteria

Also Published As

Publication number Publication date
US20190101535A1 (en) 2019-04-04
US20130183697A1 (en) 2013-07-18
US20150337396A1 (en) 2015-11-26
US20190101534A1 (en) 2019-04-04
US20190277848A1 (en) 2019-09-12
US9103829B2 (en) 2015-08-11
US20140342927A1 (en) 2014-11-20
US20160313329A1 (en) 2016-10-27
WO2008051285A2 (fr) 2008-05-02
US20230194523A1 (en) 2023-06-22
US10274493B2 (en) 2019-04-30
US20080014582A1 (en) 2008-01-17
US20130059307A1 (en) 2013-03-07
US8628928B2 (en) 2014-01-14
WO2008051285A3 (fr) 2009-04-02
US10036748B2 (en) 2018-07-31
US20170336410A1 (en) 2017-11-23

Similar Documents

Publication Publication Date Title
US20230194523A1 (en) Methods and compositions for detecting fungi and mycotoxins
US20220170931A1 (en) Methods and compositions for detecting mycotoxins
US20100075322A1 (en) Methods and Compositions for Identifying Mycotoxins and Fungal Species
US10793920B2 (en) Methods and compositions for identifying yeast
US9150934B2 (en) Methods and compositions for detecting Aspergillus terreus, Aspergillus niger, and mycotoxins
Mendonca et al. Fungal infections diagnosis–past, present and future
WO2008122310A1 (fr) Procédé de détection d'un analyte dans une matrice biologique
Vabret et al. Comparison of three non-nested RT-PCR for the detection of influenza A viruses
US20200299788A1 (en) Methods and compositions for identifying and quantifying microbial dna
US20120107809A1 (en) Method for simultaneously detecting histoplasma capsulatum and paracoccidioides brasiliensis

Legal Events

Date Code Title Description
AS Assignment

Owner name: MEDICAL SERVICE CONSULTATION INTERNATIONAL, LLC, T

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:HOOPER, DENNIS G;REEL/FRAME:019542/0409

Effective date: 20070424

STCF Information on status: patent grant

Free format text: PATENTED CASE

CC Certificate of correction
AS Assignment

Owner name: ADVATECT DIAGNOSTICS, LLC, TEXAS

Free format text: CHANGE OF NAME;ASSIGNOR:MEDICAL SERVICE CONSULTATION INTERNATIONAL, L.L.C.;REEL/FRAME:043026/0923

Effective date: 20170417

MAFP Maintenance fee payment

Free format text: PAYMENT OF MAINTENANCE FEE, 4TH YR, SMALL ENTITY (ORIGINAL EVENT CODE: M2551); ENTITY STATUS OF PATENT OWNER: SMALL ENTITY

Year of fee payment: 4

FEPP Fee payment procedure

Free format text: MAINTENANCE FEE REMINDER MAILED (ORIGINAL EVENT CODE: REM.); ENTITY STATUS OF PATENT OWNER: SMALL ENTITY

FEPP Fee payment procedure

Free format text: 7.5 YR SURCHARGE - LATE PMT W/IN 6 MO, SMALL ENTITY (ORIGINAL EVENT CODE: M2555); ENTITY STATUS OF PATENT OWNER: SMALL ENTITY

MAFP Maintenance fee payment

Free format text: PAYMENT OF MAINTENANCE FEE, 8TH YR, SMALL ENTITY (ORIGINAL EVENT CODE: M2552); ENTITY STATUS OF PATENT OWNER: SMALL ENTITY

Year of fee payment: 8

AS Assignment

Owner name: RTL PURCHASER LLC, WASHINGTON

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:ADVATECT DIAGNOSTICS, LLC;REEL/FRAME:066874/0772

Effective date: 20240318