US8863998B2 - Liquid dispensing device - Google Patents

Liquid dispensing device Download PDF

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Publication number
US8863998B2
US8863998B2 US13/418,159 US201213418159A US8863998B2 US 8863998 B2 US8863998 B2 US 8863998B2 US 201213418159 A US201213418159 A US 201213418159A US 8863998 B2 US8863998 B2 US 8863998B2
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United States
Prior art keywords
wall
valve
fastener
tubular wall
tubular
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Active
Application number
US13/418,159
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English (en)
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US20120223106A1 (en
Inventor
Gaetan Painchaud
Guillaume Grevin
Thierry Decock
Xavier Julia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nemera la Verpilliere SAS
Original Assignee
Rexam Healthcare La Verpilliere SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Assigned to REXAM HEALTHCARE LA VERPILLIERE reassignment REXAM HEALTHCARE LA VERPILLIERE ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: DECOCK, THIERRY, GREVIN, GUILLAUME, JULIA, XAVIER, PAINCHAUD, GAETAN
Publication of US20120223106A1 publication Critical patent/US20120223106A1/en
Assigned to CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH, AS AGENT reassignment CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH, AS AGENT FIRST LIEN PATENT SECURITY AGREEMENT Assignors: NEMERA LA VERPILLIERE SAS (FORMERLY KNOWN AS REXAM HEALTHCARE LA VERPILLIERE SAS)
Assigned to CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH, AS AGENT reassignment CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH, AS AGENT SECOND LIEN PATENT SECURITY AGREEMENT Assignors: NEMERA LA VERPILLIERE SAS (FORMERLY KNOWN AS REXAM HEALTHCARE LA VERPILLIERE SAS)
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Publication of US8863998B2 publication Critical patent/US8863998B2/en
Assigned to NEMERA LA VERPILLIERE SAS (F/K/A REXAM HEALTHCARE LA VERPILLIERE SAS) reassignment NEMERA LA VERPILLIERE SAS (F/K/A REXAM HEALTHCARE LA VERPILLIERE SAS) RELEASE OF SECURITY INTEREST IN INTELLECTUAL PROPERTY COLLATERAL AT REEL/FRAME NO. 33500/0061 Assignors: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
Assigned to NEMERA LA VERPILLIERE SAS (F/K/A REXAM HEALTHCARE LA VERPILLIERE SAS) reassignment NEMERA LA VERPILLIERE SAS (F/K/A REXAM HEALTHCARE LA VERPILLIERE SAS) RELEASE OF SECURITY INTEREST IN INTELLECTUAL PROPERTY COLLATERAL AT REEL/FRAME NO. 33500/0069 Assignors: CREDIT SUISSE AG, CAYMAN ISLANDS BRANCH
Assigned to NEMERA LA VERPILLIERE reassignment NEMERA LA VERPILLIERE CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). Assignors: REXAM HEALTHCARE LA VERPILLIERE
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Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00—Closures with filling and discharging, or with discharging, devices
    • B65D47/04—Closures with discharging devices other than pumps
    • B65D47/20—Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge
    • B65D47/2018—Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure
    • B65D47/2031—Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure the element being formed by a slit, narrow opening or constrictable spout, the size of the outlet passage being able to be varied by increasing or decreasing the pressure
    • B05B11/0021—
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0037—Containers
    • B05B11/0039—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means
    • B05B11/0044—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means
    • B05B11/00444—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means with provision for filtering or cleaning the air flow drawn into the container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00—Closures with filling and discharging, or with discharging, devices
    • B65D47/04—Closures with discharging devices other than pumps
    • B65D47/20—Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge
    • B65D47/2018—Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure
    • B65D47/2056—Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure lift valve type
    • B65D47/2081—Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure lift valve type in which the deformation raises or lowers the valve port
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining

Definitions

  • the invention relates to the field of dispensing liquid in the form of drops, in particular in the field of pharmaceuticals, e.g. a liquid for eyedrops or eardrops.
  • Document U.S. Pat. No. 5,154,325 discloses a liquid dispenser device including an elastomer diaphragm forming a valve member that is disposed between a support and a housing that are mounted on the container.
  • the diaphragm includes a peripheral annular bead and it is held on the device by pinching the bead between the top surface of the support and the bottom surface of the housing. The diaphragm is thus held in the device by being pinched along the axial direction of the device.
  • a drawback of that type of assembly lies in the fact that when the user squeezes the container in order to expel liquid, the liquid exerts pressure on the diaphragm in the axial direction in order to open it, and such pressure may give rise to liquid leaking at the periphery of the diaphragm. This risk of leaks is made that much more probable when the parts present dimensions or relative positions that might vary as a result of manufacturing tolerances.
  • the presence of a leak from the device is troublesome, particularly if the liquid does not include any preservative, since the liquid is then to be found at non-desirable locations in the device and that encourages bacteria to develop, which can consequently contaminate the liquid.
  • a particular object of the present invention is to provide a dispenser device in which sterility is improved.
  • the invention provides in particular a liquid dispenser device including a valve comprising:
  • the inner and outer tubular walls are arranged in such a manner that they apply radial compression to the fastener wall of the valve, i.e. they press against both sides of the fastener wall in the radial direction, corresponding to the direction that is perpendicular to the axis of the tubular walls, this radial compression serving to seal the valve.
  • the dispenser device in the valve fastener zone, has three concentric tubes, possibly short in length, the inner tube corresponding to the inner tubular wall, the intermediate tube corresponding to the fastener wall of the valve, and the outer tube corresponding to the outer tubular wall.
  • These tubes all have the same axis corresponding to the axis of the dispenser device, this axis generally being an axis of revolution of the device, in particular of the container, corresponding to the direction in which liquid leaves the valve member.
  • the diameter of the inner tubular wall is slightly greater than the diameter of the fastener wall that in turn is slightly greater than the diameter of the outer tubular wall.
  • valve is less than when the valve is fastened by clamping in the axial direction, which corresponds generally to the direction in which the fastener elements are assembled together, and which tends to cause the fastener elements to move and thus to give rise to leaks. It can be understood that the proposed configuration generates less stress on the fastener elements and thus provides better sealing, so the device is more sterile and operates well.
  • the proposed device requires less accuracy for the dimensions of the fastener elements. Pinching via tubes guarantees good sealing even if the relative positions of the components vary a little in the axial direction as a result of manufacturing tolerances or of positioning tolerances during assembly in the axial direction.
  • the outer or inner tubular wall may advantageously constitute a wall for centering the valve, thereby facilitating assembly thereof.
  • tubular walls is advantageous in terms of compactness.
  • the axial position of the fastener zone may be more situated in the downstream direction of the dispenser device, e.g. on either side of the valvemember-forming portion, thus making it possible to reduce the diameter of the dispenser endpiece.
  • sealing is exerted by tubular walls serves to increase the area of the compression exerted by the fastener elements, thereby providing better sealing.
  • the proposed device is very useful when it is desired to dispense a liquid that does not include any preservative. With a liquid of this type, it is necessary to ensure that sealing is particularly reliable.
  • the device may also include one or more of the following characteristics.
  • the outer tubular wall is carried by a support mounted on the container.
  • the support includes a valve seat that is substantially in the form of a disk, being delimited by the outer tubular wall.
  • This outer tubular wall preferably projects from the distal face of the disk (from its face that is closer to the liquid dispenser end).
  • the support presents the general shape of a circular tray with its tubular portion constituting an edge of height that is sufficient to be sandwiched between the inner and outer tubular walls.
  • the valve seat further includes a cylindrical central portion having its distal end forming a bearing surface for the valvemember-forming portion of the valve when in the liquid-blocking configuration. Also preferably, this central portion projects from the distal face of the disk.
  • the valve includes a screen delimited at its periphery by the fastener wall.
  • the valve also includes a cylindrical central portion that projects from the screen and that has its distal end constituting the valvemember-forming portion of the valve.
  • the valve has a shape that is complementary to a support portion.
  • the inner tubular wall is carried by a housing that is mounted on the container, covering the valve at least in part.
  • the housing preferably includes a central orifice through which the distal end of the valve passes.
  • the housing includes a groove defined by the inner tubular wall, a bottom wall, and an outer shell, this groove sandwiching the fastener wall of the valve together with the outer tubular wall.
  • the device includes snap-fastener means for snap-fastening the housing on the support.
  • the snap-fastening is preferably performed in the axial direction, i.e. the parts are moved towards each other in the axial direction in order to snap-fasten them together.
  • the snap-fastener means for snap-fastening are configured in such a manner that snap-fastening also corresponds to permanently fastening the valve by pinching between the inner tubular wall and the outer tubular wall.
  • valvemember-forming portion of the valve and the fastener edge of the valve are made of elastomer material.
  • the valve includes a rigid portion, preferably acting as a bearing surface for a spring.
  • the invention also provides a method of assembling the device, the method comprising the following successive steps:
  • FIG. 1 is a section view of a dispenser device in an embodiment
  • FIGS. 2 a to 2 d are perspective views showing the method of assembling the FIG. 1 device.
  • FIG. 1 shows a device 10 for dispensing liquid in the form of drops.
  • the dispensed liquid is a pharmaceutical liquid, such as a liquid for forming eyedrops or eardrops.
  • the device 10 comprises a dispenser endpiece 12 screw-fastened on the neck of a container 13 .
  • the device 10 is configured so as to dispense liquid as a result of the user squeezing the container 13 .
  • the container is elastically deformable so as to return to its previous shape after being squeezed by a user.
  • the endpiece 12 comprises a support 14 , a valve 16 , a spring 17 , a housing 18 , and a hydrophobic filter 20 .
  • the support 14 comprises a fastener portion 22 disposed at the proximal end of the endpiece for fastening the support on the container 13 .
  • This portion 22 comprises an outer skirt 24 tapped so as to be screw-fastened on the neck of the container 13 , and an inner skirt 26 of tubular shape serving to provide sealing between the container 13 and the dispenser endpiece 12 .
  • the support 14 also includes an intermediate portion 28 forming a seat for the valve 16 .
  • This intermediate portion 28 is substantially in the form of a disk extending in a radial plane R perpendicular to the axis X.
  • the disk 28 On its distal face, the disk 28 is delimited by a tubular outer wall 30 .
  • This wall forms a peripheral skirt of the disk 28 , and it extends perpendicularly to the disk 28 in the form of a tube of axis X that is sufficiently tall to receive the valve 16 , as described below.
  • the disk 28 Near the bottom end of the tubular wall 30 , the disk 28 includes an annular rib 32 serving to define a groove for centering and receiving the edge of the valve 16 .
  • the disk 28 also has a cylindrical central portion 34 for closing the valve, which portion projects from its center from the distal side of the disk 28 and carries at its distal end a bearing surface 36 of the valve 16 .
  • This portion 34 forms a shutter peg enabling the valve 16 to open or close.
  • the disk 28 is also pierced by a channel 38 for passing liquid coming from the container.
  • the channel 38 opens out to a cavity 40 delimited in particular by a recess formed in the distal surface of the disk 28 .
  • This cavity 40 also opens out to a second channel 42 for passing liquid, defined between the peg 34 and the valve 16 .
  • the channels 38 and 42 are of axes substantially parallel to the axis X. As can be seen in FIG. 1 , the disk 28 , the outer tubular wall 30 , and the shutter peg 34 together define a tubular cavity for receiving the valve 16 .
  • the support 14 has a channel 44 for passing air into the container, the channel 44 opening out into a housing 46 for receiving the hydrophobic filter 20 , the housing 46 being cylindrical and open at its proximal end into which the filter 20 is inserted.
  • the valve 16 has a central cylindrical portion 48 , an annular peripheral skirt 50 , the central portion 48 and the skirt 50 being connected together by a screen 52 of material. On its distal surface, the screen 52 carries a bearing surface 53 for the spring 17 .
  • the distal portion 54 of the central portion 48 is a portion forming a valve member for blocking or passing liquid by co-operating with the bearing surface 36 .
  • the surface 36 forms a bearing surface for the valvemember-forming portion 54 when said portion is in its liquid-blocking configuration.
  • the top surface of the portion 48 includes a liquid ejection channel 56 that opens out into a drop-metering shape 58 .
  • the skirt 50 forms a fastener edge for fastening the valve 16 on the support, for fastening the valve permanently relative to the container 13 . It is constituted by a tubular fastener wall 50 of axis X and of diameter that is slightly greater than the inside diameter of the outer tubular wall 30 .
  • valve 16 is made entirely out of an elastomer material. Nevertheless, it is possible for the valve to include certain portions that are made of an elastomer material and others out of a material that is more rigid, in particular the portion 53 forming a bearing surface for the spring 17 .
  • the valvemember-forming portion 54 , the screen 52 , and the fastener wall 50 are preferably made of elastomer material.
  • the housing 18 is mounted onto the support 16 by snap-fastener means 59 .
  • the snap-fastener means 59 enable the housing 18 to be snap-fastened relative to the support 14 when they are assembled together along the axial direction X. It carries an inner tubular wall 60 about the axis X and of diameter that is slightly greater than the diameter of the valve fastener wall 50 .
  • the housing 18 also includes an outer shell 62 forming an outer skirt that extends in the proximal direction relative to the remainder of the housing 18 , and also a bottom wall 64 configured in such a manner that the wall 60 , the bottom wall 64 and the shell 62 define a groove 63 for sandwiching the fastener wall 50 and the outer tubular wall 30 .
  • the housing 18 covers a major fraction of the valve 16 , but it is nevertheless pierced in its center by the central portion 48 of the valve.
  • the housing 18 defines a cylindrical cavity by means of a tubular inner skirt 66 having the function of centering the valve 16 .
  • the skirt 66 also defines a groove 68 forming a bearing seat for the spring 17 .
  • the fluid When a user squeezes the container 13 , the fluid is subjected to pressure and since it cannot pass via the hydrophobic filter 20 it flows into the channel 38 and then into the cavity 40 and the channel 42 .
  • the pressure of the fluid in the channel 42 deforms the valvemember-forming portion 54 so as to cause it to move from its liquid-blocking configuration to a liquid-passing configuration by the portion 54 lifting off the bearing surface 36 .
  • This deformation is made easier by the spring 17 being compressed under the pressure of the liquid. The liquid is thus dispensed in the form of drops.
  • Assembly comprises a step of assembling the endpiece 12 , then followed by a step of screwing the endpiece 12 onto the container 13 .
  • Assembly of the endpiece 12 begins by a step of installing the valve 16 on the support 14 by inserting the fastener wall 50 of the valve inside the tubular wall 30 of the support 14 . This step is shown in FIG. 2 a and it is followed by a step of inserting the spring 17 around the central portion 48 of the valve, shown in FIG. 2 b . Once the spring is in place, there follows a step of installing the housing 18 on the valve 16 , as shown in FIG. 2 c by inserting the inner tubular wall 60 inside the fastener wall 50 . This installation of the housing 18 is terminated by snap-fastening the housing on the support 14 , shown in FIG.
  • the static sealing provided around the fastener wall 50 by pinching of the walls 60 and 30 is particularly effective.
  • liquid escapes from the container 13 it exerts pressure on the valve 16 in the direction X, and this pressure in the direction X is not transferred to the fastener portion 50 , since fastening of the valve is provided by compression in the radial direction R.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Closures For Containers (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Springs (AREA)
  • Check Valves (AREA)
  • Feeding And Controlling Fuel (AREA)
  • Devices For Dispensing Beverages (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
US13/418,159 2009-09-11 2012-03-12 Liquid dispensing device Active US8863998B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0956278 2009-09-11
FR0956278A FR2950036B1 (fr) 2009-09-11 2009-09-11 Dispositif de distribution de liquide
PCT/FR2010/051877 WO2011030062A1 (fr) 2009-09-11 2010-09-09 Dispositif de distribution de liquide

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2010/051877 Continuation WO2011030062A1 (fr) 2009-09-11 2010-09-09 Dispositif de distribution de liquide

Publications (2)

Publication Number Publication Date
US20120223106A1 US20120223106A1 (en) 2012-09-06
US8863998B2 true US8863998B2 (en) 2014-10-21

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Application Number Title Priority Date Filing Date
US13/418,159 Active US8863998B2 (en) 2009-09-11 2012-03-12 Liquid dispensing device

Country Status (10)

Country Link
US (1) US8863998B2 (zh)
EP (4) EP3090957B1 (zh)
JP (1) JP5739890B2 (zh)
CN (1) CN102712395B (zh)
BR (1) BR112012005428B1 (zh)
ES (1) ES2961272T3 (zh)
FR (1) FR2950036B1 (zh)
IN (1) IN2012DN02150A (zh)
PL (1) PL3090957T3 (zh)
WO (1) WO2011030062A1 (zh)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140054330A1 (en) * 2012-08-21 2014-02-27 Aptar France S.A.S. Valve-controlled dispensing closure
US20140231536A1 (en) * 2011-09-22 2014-08-21 Xavier Julia Device For Distributing Liquid In The Form Of Drops
US20150273504A1 (en) * 2014-03-25 2015-10-01 Albea Le Treport System for Distributing a Fluid Product Which is Packaged in a Tank
US10214309B2 (en) * 2014-09-24 2019-02-26 Rpc Bramlage Gmbh Plastic tube designed for pressing out a liquid to pasty mass
US10813923B1 (en) 2015-04-23 2020-10-27 Sydnexis, Inc. Ophthalmic composition
US10829276B2 (en) * 2017-02-01 2020-11-10 Silgan Dispensing Systems Hemer Gmbh Dispenser for a liquid
US11052095B2 (en) 2015-05-29 2021-07-06 Sydnexis, Inc. D2O stabilized pharmaceutical formulations
EP3978389A1 (de) * 2020-10-02 2022-04-06 Aptar Radolfzell GmbH Flüssigkeitsspender, insbesondere tropfenspender
US11382909B2 (en) 2014-09-05 2022-07-12 Sydnexis, Inc. Ophthalmic composition
US11439756B2 (en) 2017-08-30 2022-09-13 Novo Nordisk A/S Flow communication unit with preservative
US11596625B2 (en) 2014-06-24 2023-03-07 Sydnexis, Inc. Ophthalmic composition
US11679028B2 (en) 2019-03-06 2023-06-20 Novartis Ag Multi-dose ocular fluid delivery system
US20230271207A1 (en) * 2022-02-28 2023-08-31 L'oreal Cosmetic Dispenser with Accordion Bladder Valve System
US11819453B2 (en) 2015-01-12 2023-11-21 Novartis Ag Micro-droplet delivery device and methods
US11925577B2 (en) 2020-04-17 2024-03-12 Bausch + Lomb Ireland Limted Hydrodynamically actuated preservative free dispensing system
US11938057B2 (en) 2020-04-17 2024-03-26 Bausch + Lomb Ireland Limited Hydrodynamically actuated preservative free dispensing system
US11944791B2 (en) 2017-08-30 2024-04-02 Novo Nordisk A/S Multi-use drug delivery device for drugs with less preservatives

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2929249B1 (fr) 2008-03-27 2012-02-17 Rexam Pharma La Verpilliere Dispositif de distribution de liquide contenu dans un reservoir
FR2937019B1 (fr) * 2008-10-15 2012-06-08 Rexam Pharma La Verpilliere Dispositif de distribution de liquide muni d'un organe d'etancheite ayant une partie elastomere
GB2474520B (en) 2009-10-19 2015-08-26 London & General Packaging Ltd Spray dispenser
FR2989290B1 (fr) * 2012-04-17 2014-05-16 Rexam Dispensing Sys Systeme de distribution d’un produit fluide contenu dans un recipient
FR3080844B1 (fr) * 2018-05-07 2020-06-05 Horus Pharma Dispositif de conditionnement et distribution d'un produit avec flacon et embout doseur muni d'un filtre

Citations (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3441179A (en) * 1967-05-29 1969-04-29 Ways & Means Inc Mixing container
FR2377338A1 (fr) 1977-01-18 1978-08-11 Laauwe Robert H Flacon compressible a clapet pour distribuer des produits visqueux
US5025957A (en) * 1988-10-07 1991-06-25 Ryder International Corp. Liquid dispenser nozzle assembly
US5154325A (en) * 1991-01-09 1992-10-13 Ryder International Corporation Solution delivery nozzle and system with antimicrobial features
US5240149A (en) 1990-05-14 1993-08-31 Perfect-Valois Ventil Gmbh Closure cap
US5320254A (en) * 1988-10-07 1994-06-14 Ryder International Corp. Liquid dispenser nozzle assembly
US5431310A (en) * 1988-10-07 1995-07-11 Ryder International Corporation Liquid dispenser nozzle assembly
US5692651A (en) 1996-06-06 1997-12-02 Owens-Illinois Closure Inc. Self-sealing dispensing closure
WO2000029296A1 (en) 1998-11-17 2000-05-25 Crown Cork & Seal Technologies Corporation Dispensing closures
JP2000226050A (ja) 1999-02-01 2000-08-15 Waterfall Co Inc 流動可能物質を送給し且つ無菌性及び完全性を維持するシステム
EP1266840A2 (en) 2001-06-15 2002-12-18 Taisai Kako Co., Ltd. A dispensing container
WO2003089325A2 (de) 2002-04-19 2003-10-30 Gaplast Gmbh Einwegventil zur abgabe eines fliessfähigen materials
FR2846945A1 (fr) 2002-11-04 2004-05-14 Owens Illinois Closure Inc Dispositif de fermeture pour distribution de fluide a fermeture automatique.
EP1614636A1 (en) 2004-07-09 2006-01-11 Sara Lee/DE N.V. Closure device
US7303098B2 (en) * 2002-01-09 2007-12-04 Gaplast Gmbh Valve for the application of drops
US7516874B2 (en) * 2003-01-30 2009-04-14 Gaplast Gmbh One-way valve device

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3008611A (en) * 1958-03-31 1961-11-14 Chapman Machine Company Inc Sealing and dispensing device
JPS613249U (ja) * 1984-06-11 1986-01-10 株式会社吉野工業所 クリ−ム状物注出容器
US4699301A (en) * 1985-10-25 1987-10-13 Blake William S Two piece dispensing closure
DE19627228A1 (de) * 1996-07-05 1998-01-08 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für Medien
JP3652458B2 (ja) * 1996-11-19 2005-05-25 株式会社吉野工業所 内容物吐出容器のスリットバルブ保持手段
US6749092B2 (en) * 2001-08-10 2004-06-15 Seaquist Closures Foreign, Inc. Deformable dispensing valve
DE10157423A1 (de) 2001-11-25 2003-06-05 Roland Knauer Behälter mit elastischem Ventil
US7249694B2 (en) * 2002-07-26 2007-07-31 Masatoshi Masuda Valve mechanism for tube-type fluid container
MX2008012583A (es) * 2006-03-28 2008-10-10 Otsuka Pharma Co Ltd Contenedor de descarga y contenedor de colirio.
ITMO20060252A1 (it) 2006-08-04 2008-02-05 Mrp Medical Res & Promotion Es Flacone per il contenimento di fluidi, particolarmente per prodotti farmaceutici o simili

Patent Citations (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3441179A (en) * 1967-05-29 1969-04-29 Ways & Means Inc Mixing container
FR2377338A1 (fr) 1977-01-18 1978-08-11 Laauwe Robert H Flacon compressible a clapet pour distribuer des produits visqueux
US5025957A (en) * 1988-10-07 1991-06-25 Ryder International Corp. Liquid dispenser nozzle assembly
US5320254A (en) * 1988-10-07 1994-06-14 Ryder International Corp. Liquid dispenser nozzle assembly
US5431310A (en) * 1988-10-07 1995-07-11 Ryder International Corporation Liquid dispenser nozzle assembly
US5240149A (en) 1990-05-14 1993-08-31 Perfect-Valois Ventil Gmbh Closure cap
US5154325A (en) * 1991-01-09 1992-10-13 Ryder International Corporation Solution delivery nozzle and system with antimicrobial features
US5692651A (en) 1996-06-06 1997-12-02 Owens-Illinois Closure Inc. Self-sealing dispensing closure
WO2000029296A1 (en) 1998-11-17 2000-05-25 Crown Cork & Seal Technologies Corporation Dispensing closures
JP2000226050A (ja) 1999-02-01 2000-08-15 Waterfall Co Inc 流動可能物質を送給し且つ無菌性及び完全性を維持するシステム
EP1266840A2 (en) 2001-06-15 2002-12-18 Taisai Kako Co., Ltd. A dispensing container
US20020190079A1 (en) * 2001-06-15 2002-12-19 Taisei Kako Co., Ltd Dispensing container
US7303098B2 (en) * 2002-01-09 2007-12-04 Gaplast Gmbh Valve for the application of drops
WO2003089325A2 (de) 2002-04-19 2003-10-30 Gaplast Gmbh Einwegventil zur abgabe eines fliessfähigen materials
US8322578B2 (en) * 2002-04-19 2012-12-04 Gaplast Gmbh One-way valve for delivering a free-flowing material
FR2846945A1 (fr) 2002-11-04 2004-05-14 Owens Illinois Closure Inc Dispositif de fermeture pour distribution de fluide a fermeture automatique.
US6896151B1 (en) * 2002-11-04 2005-05-24 Owens-Illinois Closure Inc. Self-closing fluid dispensing closure
US7516874B2 (en) * 2003-01-30 2009-04-14 Gaplast Gmbh One-way valve device
EP1614636A1 (en) 2004-07-09 2006-01-11 Sara Lee/DE N.V. Closure device

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
International Search Report; Application No. PCT/FR2010/051877; Issued: Nov. 18, 2010; Mailing Date: Dec. 1, 2010; 3 pages.
Japanese Notice of Reasons for Rejection and Translation thereof Application No. 2012-528426 Mailing Date: Feb. 4, 2014 8 pages.

Cited By (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140231536A1 (en) * 2011-09-22 2014-08-21 Xavier Julia Device For Distributing Liquid In The Form Of Drops
US11033922B2 (en) * 2011-09-22 2021-06-15 Nemera La Verpillière Device for distributing liquid in the form of drops
US20140054330A1 (en) * 2012-08-21 2014-02-27 Aptar France S.A.S. Valve-controlled dispensing closure
US20150273504A1 (en) * 2014-03-25 2015-10-01 Albea Le Treport System for Distributing a Fluid Product Which is Packaged in a Tank
US9757749B2 (en) * 2014-03-25 2017-09-12 Albea Le Treport System for distributing a fluid product which is packaged in a tank
US11890277B2 (en) 2014-06-24 2024-02-06 Sydnexis, Inc. Ophthalmic composition
US11596625B2 (en) 2014-06-24 2023-03-07 Sydnexis, Inc. Ophthalmic composition
US11896588B2 (en) 2014-06-24 2024-02-13 Sydnexis, Inc. Ophthalmic composition
US11883390B2 (en) 2014-06-24 2024-01-30 Sydnexis, Inc. Ophthalmic composition
US11382909B2 (en) 2014-09-05 2022-07-12 Sydnexis, Inc. Ophthalmic composition
US10214309B2 (en) * 2014-09-24 2019-02-26 Rpc Bramlage Gmbh Plastic tube designed for pressing out a liquid to pasty mass
US11819453B2 (en) 2015-01-12 2023-11-21 Novartis Ag Micro-droplet delivery device and methods
US10940145B2 (en) 2015-04-23 2021-03-09 Sydnexis, Inc. Ophthalmic composition
US10953002B2 (en) 2015-04-23 2021-03-23 Sydnexis, Inc. Ophthalmic composition
US10888557B2 (en) 2015-04-23 2021-01-12 Sydnexis, Inc. Ophthalmic composition
US10813923B1 (en) 2015-04-23 2020-10-27 Sydnexis, Inc. Ophthalmic composition
US11052094B2 (en) 2015-05-29 2021-07-06 Sydnexis, Inc. D2O stabilized pharmaceutical formulations
US11052095B2 (en) 2015-05-29 2021-07-06 Sydnexis, Inc. D2O stabilized pharmaceutical formulations
US10829276B2 (en) * 2017-02-01 2020-11-10 Silgan Dispensing Systems Hemer Gmbh Dispenser for a liquid
US11225362B2 (en) * 2017-02-01 2022-01-18 Silgan Dispensing Systems Hemer Gmbh Dispenser for a liquid
US11944791B2 (en) 2017-08-30 2024-04-02 Novo Nordisk A/S Multi-use drug delivery device for drugs with less preservatives
US11439756B2 (en) 2017-08-30 2022-09-13 Novo Nordisk A/S Flow communication unit with preservative
US11679028B2 (en) 2019-03-06 2023-06-20 Novartis Ag Multi-dose ocular fluid delivery system
US11938057B2 (en) 2020-04-17 2024-03-26 Bausch + Lomb Ireland Limited Hydrodynamically actuated preservative free dispensing system
US11925577B2 (en) 2020-04-17 2024-03-12 Bausch + Lomb Ireland Limted Hydrodynamically actuated preservative free dispensing system
EP3978389A1 (de) * 2020-10-02 2022-04-06 Aptar Radolfzell GmbH Flüssigkeitsspender, insbesondere tropfenspender
US11759797B2 (en) 2020-10-02 2023-09-19 Aptar Radolfzell Gmbh Liquid dispenser, especially droplet dispenser
EP4212451A1 (de) * 2020-10-02 2023-07-19 Aptar Radolfzell GmbH Tropfenspender
US11904330B2 (en) * 2022-02-28 2024-02-20 L'oreal Cosmetic dispenser with accordion bladder valve system
US20230271207A1 (en) * 2022-02-28 2023-08-31 L'oreal Cosmetic Dispenser with Accordion Bladder Valve System

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BR112012005428B1 (pt) 2019-07-09
FR2950036A1 (fr) 2011-03-18
JP5739890B2 (ja) 2015-06-24
CN102712395A (zh) 2012-10-03
EP3090956A1 (fr) 2016-11-09
BR112012005428A2 (pt) 2016-04-12
FR2950036B1 (fr) 2011-12-16
EP3090957A1 (fr) 2016-11-09
US20120223106A1 (en) 2012-09-06
ES2961272T3 (es) 2024-03-11
IN2012DN02150A (zh) 2015-08-07
EP2475585B1 (fr) 2018-01-17
JP2013504496A (ja) 2013-02-07
EP3090957B1 (fr) 2023-08-09
WO2011030062A1 (fr) 2011-03-17
EP4147990A1 (fr) 2023-03-15
PL3090957T3 (pl) 2024-01-03
EP2475585A1 (fr) 2012-07-18
CN102712395B (zh) 2015-02-11

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