US6395327B1 - Enhanced fatigue strength orthopaedic implant with porous coating and method of making same - Google Patents

Enhanced fatigue strength orthopaedic implant with porous coating and method of making same Download PDF

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Publication number
US6395327B1
US6395327B1 US09/267,272 US26727299A US6395327B1 US 6395327 B1 US6395327 B1 US 6395327B1 US 26727299 A US26727299 A US 26727299A US 6395327 B1 US6395327 B1 US 6395327B1
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Prior art keywords
implant
substrate
metallic particles
fatigue strength
porous layer
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US09/267,272
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H. Ravindranath Shetty
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Zimmer Inc
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Zimmer Inc
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Assigned to BRISTOL-MYERS SQUIBB CO. reassignment BRISTOL-MYERS SQUIBB CO. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: SHETTY, H. RAVINDRANATH
Priority to US09/267,272 priority Critical patent/US6395327B1/en
Application filed by Zimmer Inc filed Critical Zimmer Inc
Priority to CA2706685A priority patent/CA2706685C/en
Priority to CA2706686A priority patent/CA2706686C/en
Priority to AU20650/00A priority patent/AU771070B2/en
Priority to CA2299939A priority patent/CA2299939C/en
Priority to EP00200891.0A priority patent/EP1035230B1/en
Priority to JP2000073975A priority patent/JP2000288002A/ja
Priority to US10/062,731 priority patent/US6685987B2/en
Assigned to ZIMMER, INC. reassignment ZIMMER, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: BRISTOL-MYERS SQUIBB COMPANY
Priority to US10/115,525 priority patent/US6576014B2/en
Publication of US6395327B1 publication Critical patent/US6395327B1/en
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Assigned to ZIMMER TECHNOLOGY, INC. reassignment ZIMMER TECHNOLOGY, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ZIMMER, INC.
Priority to US10/739,501 priority patent/US20040133283A1/en
Assigned to ZIMMER TECHNOLOGY, INC. reassignment ZIMMER TECHNOLOGY, INC. CORRECTIVE ASSIGNMENT TO REMOVE ERRONEOUSLY RECORDED PATENT NUMBER 4,997,433 FROM A DOCUMENT PREVIOUSLY RECORDED AT REEL 013862 FRAME 0766. Assignors: ZIMMER, INC.
Priority to JP2010131437A priority patent/JP2010259813A/ja
Assigned to ZIMMER, INC. reassignment ZIMMER, INC. MERGER (SEE DOCUMENT FOR DETAILS). Assignors: ZIMMER TECHNOLOGY, INC.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
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    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A—HUMAN NECESSITIES
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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F7/00—Manufacture of composite layers, workpieces, or articles, comprising metallic powder, by sintering the powder, with or without compacting wherein at least one part is obtained by sintering or compression
    • B22F7/002—Manufacture of composite layers, workpieces, or articles, comprising metallic powder, by sintering the powder, with or without compacting wherein at least one part is obtained by sintering or compression of porous nature
    • B22F7/004—Manufacture of composite layers, workpieces, or articles, comprising metallic powder, by sintering the powder, with or without compacting wherein at least one part is obtained by sintering or compression of porous nature comprising at least one non-porous part
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
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    • C23C24/08—Coating starting from inorganic powder by application of heat or pressure and heat
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    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2/3676—Distal or diaphyseal parts of shafts
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    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/3082—Grooves
    • A61F2002/30827—Plurality of grooves
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2002/30906—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth shot- sand- or grit-blasted
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    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
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    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
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    • A61F2/32—Joints for the hip
    • A61F2/36—Femoral heads ; Femoral endoprostheses
    • A61F2/3609—Femoral heads or necks; Connections of endoprosthetic heads or necks to endoprosthetic femoral shafts
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Definitions

  • This invention generally relates to prosthetic implants having a porous surface attached thereto and more particularly to improving the fatigue strength of a such an implant.
  • Prosthetic implants for the replacement of a portion of a patient's joints are well-known, and may be constructed of cobalt-chromium-molybdenum or titanium, for example.
  • a porous surface layer on the implant to promote fixation by allowing direct bone ingrowth and interdigitation with the implant.
  • the porous surface may receive bone cement therein to enhance the mechanical interlock with bone cement.
  • the porous surface layer typically takes the form of a plurality of small metallic particles such as beads or a wire mesh.
  • the porous surface layer is sintered, diffusion bonded, or welded to the implant. These processes require heating the implant and particles to a temperature sufficient to cause the porous surface layer and implant body to fuse, melt or bond together at their point of mutual contact.
  • a phenomenon with beaded and/or other textured surfaces is that the texturing creates a “notch effect” on the surface of the implant. If the bonded junctions were viewed in cross section, a small notch would be seen extending into the implant on each side of a contact point between the porous surface layer and the implant. This so-called “notch effect” contributes to crack formation when the implants are cyclically loaded in a fatigue mode.
  • a related phenomenon with beaded or textured surfaces is that the sintering process by which the beads are typically adhered to the implant creates an annealing effect which reduces the fatigue strength of the implant.
  • This annealing effect is particularly noticeable in forged implants which have a higher fatigue strength, due to working of the metal, than their cast counterparts before bead bonding.
  • U.S. Pat. No. 5,443,510 assigned to the assignee of the present invention and hereby incorporated by reference, discloses addressing the “notch effect” phenomenon by reducing the number of notches formed.
  • the formation of notches in the implant body can be limited by creating a thin layer of metal mesh on the surface of the implant and then bonding the porous surface layer onto the mesh.
  • U.S. Pat. No. 5,734,959 assigned to the assignee of the present invention and hereby incorporated by reference, discloses a method for enhancing the bonding between the porous surface layer and the implant.
  • An organic binder such as a water-soluble protein is used to enhance the bonding between the porous surface layer and the implant.
  • the binder carbonizes and alloys with the metal of the porous surface layer and thereby lowers the temperature of the metallic particles at the interface surfaces.
  • Other alloy materials such as silicon can also be suspended in the binder with this method. This patent does not address the notch effect phenomenon.
  • U.S. Pat. No. 5,308,412 assigned to the assignee of the present invention and hereby incorporated by reference, discloses a method for surface hardening cobalt-chromium based orthopaedic implants by a nitriding or nitrogen diffusion hardening process.
  • the '412 patent is aimed at increasing the wear-resistance properties of the surface of the implant so as to reduce the wear debris produced from articulation against polyethylene, metal, or ceramic counterfaces or by micro-motion of the implant relative to the environment contacting the implant, typically bone or bone cement.
  • the '412 patent suggests that the nitriding process disclosed therein results in minimal or no loss of fatigue properties to the implant.
  • the present invention provides an implant having enhanced fatigue strength by incorporating a substance into the implant which reduces the melting point of the substrate prior to sintering the porous layer to the substrate. In so doing, sintering can be performed at a lower temperature, which in turn significantly reduces the fatigue strength loss from a forged implant which occurs during the sintering process.
  • the present invention also provides a nitriding process and thermal processes to which the implant can be subjected after the sintering process is completed.
  • the nitriding or nitrogen diffusion hardening process and the thermal processes further increase the fatigue strength of a cast or forged implant.
  • the present invention provides a method for forming a porous layer on a forged orthopaedic implant.
  • an orthopaedic implant substrate formed from a forged metal alloy and having a surface adapted to support a porous layer and a plurality of metallic particles are provided.
  • a substance is incorporated into the forged substrate which substance reduces the melting point of the substrate.
  • the substrate surface and the metallic particles are brought into contact with one another and heated to a temperature less than the reduced melting point, whereby the particles bond to the surface.
  • the forged alloy is cobalt-chromium-molybdenum alloy.
  • the melting point lowering substance can be carbon, silicon, nitrogen, niobium, columbium, tantalum, chromium carbides, chromium nitrides, chromium silicides, molybdenum silicides, chromium borides, silicon carbides, silicon nitrides, titanium carbides, titanium aluminides, titanium silicides, zirconium carbides or zirconium silicides.
  • One advantage of the method described above is that it compensates for the “notch effect” and the reduction in fatigue strength which results from the high temperatures and long times involved in sintering. That is, the method in accordance with the present invention provides a forged implant which maintains most of its fatigue strength through the sintering process.
  • the present invention comprises a method for increasing the fatigue strength of an implant having a porous layer thereon.
  • the implant can be formed from either a cast or forged material.
  • An implant substrate formed from a metal alloy and having a surface adapted to support a porous layer and a plurality of metallic particles are provided.
  • the metallic particles are brought into contact with the substrate surface.
  • the metallic particles and implant substrate are heated to a temperature sufficient to sinter the particles to the surface, whereby the particles bond to the surface and form a porous layer.
  • the implant is gas quenched down to at least room temperature.
  • the substrate is then heated to an aging temperature range of about 800° F. to 2100° F. and aged at the aging temperature for 1 to 100 hours.
  • the method includes gas quenching the implant to below ⁇ 90° F. or between ⁇ 90° F. and ⁇ 30° F. during the gas quenching step.
  • thermal processing methods are that they can be used in addition to or separately from the method of incorporating a melting point lowering substance into the substrate.
  • inventive thermal processing methods can be used to enhance the strength of forged or cast parts, and can be used with porous coated or uncoated implants.
  • the present invention provides a method of increasing the fatigue strength of a beaded implant.
  • the implant can be forged or cast.
  • a beaded orthopaedic implant substrate is provided and then exposed to an atmosphere of molecular nitrogen gas or atomic nitrogen at a process temperature within the range of 500° F. to 2400° F. for a process time duration sufficient to achieve increased fatigue strength.
  • An advantage of the inventive nitriding process in accordance with the present invention is that it significantly improves the fatigue strength of a cast or forged implant.
  • cast or forged implants subjected to sintering can have their fatigue strength restored by subsequently using the nitrogen diffusion hardening or nitriding process in accordance with the present invention.
  • Another advantage of the inventive methods of the present invention is that they can improve the mechanical properties of a wide variety of implants, such as for hip, knee, shoulder, elbow and other joints.
  • FIG. 1 is a perspective view of a hip stem having a porous coat attached thereto in accordance with the illustrated embodiment
  • FIG. 2 is a cross sectional view taken along line 2 — 2 of FIG. 1;
  • FIG. 3 is an enlarged fragmentary view illustrating the porous surface of the hip stem of FIG. 1 .
  • an orthopaedic implant 10 in the form of hip stem 12 comprises a substrate 11 (FIG. 2) and porous layer 14 .
  • Porous layer 14 is comprised of metallic particles.
  • the term “particles” is to be construed broadly and includes beads, fibers, wire mesh and other known materials and shapes thereof used to form porous layer 14 .
  • the particles in the illustrated embodiment are round beads 16 .
  • Beads 16 can be bonded to substrate 11 by a known sintering process in which the beads are brought into contact with the substrate and heat is applied, which causes atomic bonding of the beads to the substrate.
  • the time required to successfully sinter the particles to the substrate can be reduced with these melting point lowering substances incorporated into the substrate.
  • the melting point of beads 16 can also be lowered by incorporation of these metallic or nonmetallic elements and compounds into the beads.
  • an orthopaedic implant substrate having a surface adapted to support a porous layer and a plurality of metallic beads are provided.
  • a melting point lowering substance is then incorporated into the surface of the substrate using the commercially available methods described hereinbelow.
  • the beads are brought into contact with the surface of the substrate and fused thereto by heating to a temperature at which sintering takes place, the temperature being less than the reduced melting point produced by incorporation of the substance.
  • the sintering can be performed in a conventional sintering oven, for example, and as a result, the metallic particles bond to the substrate.
  • substrate 11 can be formed from any forged cobalt-chromium-molybdenum or other cobalt base alloys.
  • melting point lowering substances include carbon, silicon, nitrogen, niobium, (or columbium), tantalum, chromium carbides, chromium nitrides, chromium silicides, molybdenum silicides, chromium borides, silicon carbides, silicon nitrides, titanium carbides, titanium aluminides, titanium silicides, zirconium carbides and zirconium silicides.
  • Nitrogen diffusion hardening or nitriding processes involve the surface of the substrate being alloyed with nitrogen by placing the implants and/or beads in a gaseous environment of nitrogen, which results in the alloy having a reduced melting point.
  • nitrides such as CrN 2 , CoN 2 and MoN 2 are formed in a surface layer on the substrate.
  • the process of nitrogen diffusion hardening is well-known and is described, for example, in U.S. Pat. No. 5,308,412, assigned to the assignee of the present invention and hereby incorporated by reference. It has been hitherto unknown to use the process of nitrogen diffusion hardening to improve the fatigue strength of a porous coated forged implant.
  • An ion implantation process can be used to incorporate the melting point lowering substance into the implant substrate.
  • Commercially available ion implantation processes typically involve extracting a stream of ions from an ion source, accelerating and focusing them into a beam which is rastered onto the substrate.
  • thermal coating processes can also be used to coat the implant substrates and beads.
  • thermal coating processes include plasma spray coating processes, in which the substance to be incorporated is heated to a molten state and then deposited onto the metal alloy, after which the substance solidifies and mechanically bonds to the substrate.
  • Blasting the surfaces of the implants with the substances can be accomplished using commercially available blasting processes.
  • the blasting process leaves residues of the melting point lowering substances on the surface of the implants.
  • the surface of the implants have a lower melting point so that a good metallurgical bond is established between the implant surface and the beads at a lower sintering temperature.
  • Incorporation by blasting process is further advantageous in that the blasting “work hardens” the surface. Additionally, blasting produces a slightly abraded surface which helps the beads to adhere thereto.
  • melting point depressants that can be added to the alloy surface using the above-described processes are CoCO 3 , Co 2 P, CoMoO 4 , CoSi, Co 2 Si CoSi 2 , Co 3 Si, CoS, CoS 2 , etc.
  • sintering of the beads to the implant substrate can be conducted in a nitrogen or carbon atmosphere.
  • the bonding is advantageously performed in a chamber filled with nitrogen gas.
  • the atmosphere comprises greater than 99% nitrogen.
  • the bonding is advantageously performed in a chamber filled with a carbon containing gas such as carbon dioxide or methane.
  • the oxygen in the atmosphere is advantageously reduced to limit the effects of oxidation. Processing in such an enriched environment results in carbon or nitrogen being absorbed into the solid alloy substrate thereupon forming chromium, cobalt and molybdenum carbides and nitrides. The presence of the carbides and nitrides lowers the melting point of the surface of the substrate and consequently lowers the temperature at which sintering of the beads to the substrate take place.
  • Nitrogen diffusion hardening of an implant substrate to improve wear resistance properties is described in U.S. Pat. No. 5,308,412.
  • the '412 patent suggests that nitrogen diffusion hardening, at best, will not reduce the fatigue strength of an implant.
  • the inventors of the present invention have found that nitrogen diffusion hardening performed subsequent to bead bonding of a forged or cast implant actually significantly improves the fatigue strength of the implant. It is anticipated that nitrogen diffusion could be used before bead bonding to lower the diffusion bonding temperature (described above) and/or used subsequent to bead bonding to further improve fatigue strength.
  • control samples were then cycled 10 million times or until they fractured.
  • Control specimen No. 1 fractured at 55 ksi loading after 3.7 million cycles and specimen No. 2 failed at 60 ksi loading after 2.6 million cycles.
  • Specimen No. 3 did not fail at 57.5 ksi.
  • this group of samples exhibited a fatigue strength of approximately 55 ksi.
  • the nitrogen diffusion hardening was performed at 2000° F. for 2 hours, using substantially the same procedure described in U.S. Pat. No. 5,308,412.
  • the nitrogen diffusion hardening comprised exposing the implant substrate to an atmosphere of non-diluted molecular nitrogen gas at a process temperature within the range of 500° F. to 2400° F. for 0.25 to 4 hours.
  • no fracture of the nitrogen diffusion hardened substrates occurred until loading of close to 65 ksi.
  • the nitrogen diffusion hardening process significantly improves the fatigue strength of the forged beaded alloy.
  • the nitrogen diffusion hardening process can improve the fatigue strength of a cast substrate.
  • Improvements in fatigue strength can also be obtained by thermal processing after bead bonding using an aging heat treatment.
  • the bead coated implants are cooled from the sintering temperature down to approximately 2100° F.
  • the cooling to 2100° F. can be controlled or allowed to occur naturally in the furnace or oven.
  • the parts are quickly gas quenched down to at least room temperature, or lower.
  • Gas quenching is performed by subjecting the parts to a very cool gas, such as argon or nitrogen, as is widely known in the art. Without wishing to be tied to any specific theory, it is thought that the temperatures obtained during sintering, approximately 2385° F., result in a super saturated condition in the atomic microstructure of the substrate.
  • the beaded substrate is heated and aged in the temperature range of about 800-2100° F. for 1 to 100 hours, more preferably 1 to 40 hours.
  • the heating and aging takes place in an oxygen reduced atmosphere to prevent oxidation.
  • an atmosphere comprising a partial vacuum or an inert gas such as argon are suitable.
  • the aging time is inversely proportional to aging temperature, so that the time required to reach optimum fatigue strength is reduced with increasing temperature. It is thought that the carbide precipitates formed during the aging process fit within the lattice of the base alloy and increase the hardness and mechanical properties thereof.
  • the fatigue properties of aged high carbon cobalt-chromium-molybdenum alloy forgings are given in Table III. As shown in Table III, the fatigue strength of conventional high temperature (greater than 2350° F.) sintered cobalt-chromium-molybdenum alloy is reported (Example 1.). The fatigue strength is increased by the above described treatments. Reducing the sintering temperature so that it is less than or equal to 2350° F. (Example 2.) produces a significant improvement as was discussed in conjunction with Table I. It has been found that aging after bead bonding (Example 3.) results in an additive fatigue strength improvement.
  • the aging process can be useful for applications such as dental implants in addition to orthopaedic implants to improve the fatigue strength thereof Additionally, the aging process can be used for both cast as well as forged alloys.
  • the aging process produces better fatigue strength if the implant substrate is cooled to a cryogenic temperature of between ⁇ 90° F. and ⁇ 300° F. (instead of room temperature) during the quenching step. While the exact mechanism by which this cryogenic treatment operates is not understood, it is believed that cooling the substrate to cryogenic temperatures better preserves the super saturated atomic microstructure formed at sintering temperatures.
  • Specific commercially available alloys that can be used in the aging process, with or without cooling to cryogenic temperatures include Carpenter Biodur CCM Plus alloy (commercially available from Carpenter Steels of Reading, Pa.), Firth Rixson high carbon alloy (commercially available from Firth Rixson Superalloys Ltd., Derbyshire, England), Teledyne AlIvac high carbon alloy (commercially available from Teledyne Allvac or Monroe, N.C.), ASTM F-75, ASTM F-799 and ASTM F-1537.
  • Hardening and increased fatigue strength of the alloy can also be achieved by slow furnace cooling the sintered Cobalt-Chromium-Molybdenum alloy from sintering or solution treating temperatures.
  • the process parameters are not critical. Cooling in the furnace from the sintering temperature to room temperature over a period of greater than one-half hour produces the desired result. During the slow furnace cooling process, chromium carbides will precipitate in the atomic microstructure lattice and harden the alloy.

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CA2706686A CA2706686C (en) 1999-03-12 2000-03-03 Enhanced fatigue strength orthopaedic implant with porous coating and method of making same
AU20650/00A AU771070B2 (en) 1999-03-12 2000-03-03 Enhanced fatigue strength orthopaedic implant with porous coating and method of making same
CA2299939A CA2299939C (en) 1999-03-12 2000-03-03 Enhanced fatigue strength orthopaedic implant with porous coating and method of making same
EP00200891.0A EP1035230B1 (en) 1999-03-12 2000-03-13 Enhanced fatigue strength orthopaedic implant with porous coating and method of making same
JP2000073975A JP2000288002A (ja) 1999-03-12 2000-03-13 多孔質コーティングを有する疲労強度増強化整形外科用インプラント及びその製造法
US10/062,731 US6685987B2 (en) 1999-03-12 2002-01-30 Enhanced fatigue strength orthopaedic implant with porous coating and method of making same
US10/115,525 US6576014B2 (en) 1999-03-12 2002-04-03 Enhanced fatigue strength orthopaedic implant with porous coating and method of making same
US10/739,501 US20040133283A1 (en) 1999-03-12 2003-12-17 Enhanced fatigue strength orthopaedic implant with porous coating and method of making same
JP2010131437A JP2010259813A (ja) 1999-03-12 2010-06-08 多孔質コーティングを有する疲労強度増強化整形外科用インプラント及びその製造法

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