US6137289A - MR imaging method and apparatus - Google Patents

MR imaging method and apparatus Download PDF

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Publication number
US6137289A
US6137289A US09/286,256 US28625699A US6137289A US 6137289 A US6137289 A US 6137289A US 28625699 A US28625699 A US 28625699A US 6137289 A US6137289 A US 6137289A
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pulse
sub
flow compensating
phase shift
pulse sequence
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US09/286,256
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Takao Goto
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GE Healthcare Japan Corp
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GE Yokogawa Medical System Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/54Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/565Correction of image distortions, e.g. due to magnetic field inhomogeneities
    • G01R33/56572Correction of image distortions, e.g. due to magnetic field inhomogeneities caused by a distortion of a gradient magnetic field, e.g. non-linearity of a gradient magnetic field
    • G01R33/56581Correction of image distortions, e.g. due to magnetic field inhomogeneities caused by a distortion of a gradient magnetic field, e.g. non-linearity of a gradient magnetic field due to Maxwell fields, i.e. concomitant fields
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/54Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/565Correction of image distortions, e.g. due to magnetic field inhomogeneities
    • G01R33/56509Correction of image distortions, e.g. due to magnetic field inhomogeneities due to motion, displacement or flow, e.g. gradient moment nulling
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/54Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/565Correction of image distortions, e.g. due to magnetic field inhomogeneities
    • G01R33/56563Correction of image distortions, e.g. due to magnetic field inhomogeneities caused by a distortion of the main magnetic field B0, e.g. temporal variation of the magnitude or spatial inhomogeneity of B0

Definitions

  • the present invention relates to an MR (magnetic resonance) imaging method and apparatus which prevents image quality degradation which occurs when a flow compensating pulse is applied.
  • the conventional fast spin echo technique includes a pulse sequence incorporating a flow compensating pulse constituted of fcrdep and fcrrep in the read gradient (FIG. 5).
  • a pulse sequence incorporating a flow compensating pulse constituted of fcrdep and fcrrep in the read gradient By incorporating the flow compensating pulse constituted of fcrdep and fcrrep in the read gradient, image quality degradation due to flowing spins can be avoided (flow compensation).
  • the incorporation of the flow compensating pulse constituted of fcrdep and fcrrep may cause ghosts.
  • the ghosts negligibly degrade image quality and do not cause a significant problem.
  • the present invention provides an MR imaging method wherein: a flow compensating pulse is incorporated in a read gradient of a pulse sequence according to the fast spin echo technique; and a bipolar pulse is incorporated in a slice gradient before an inversion pulse applied immediately before the flow compensating pulse, to impart a phase shift equal to a non-linear phase shift due to the flow compensating pulse.
  • the reason why the ghosts are generated by incorporating the flow compensating pulse is that a non-linear spatial phase change arises in the encode axis.
  • the magnetic field involves an additional term B M (x, y, z, t) as follows to satisfy the Maxwell equation:
  • the non-linear phase shift arises because, as can be seen from the above equation, the Maxwell term B M (x, y, z, t) contains quadratic terms of x, y and z and cross terms of xz and yz.
  • the Maxwell term has a greater weight relative to the main magnetic field B 0 , and hence, the effect thereof increases.
  • the flow compensating pulse constituted of fcrdep and fcrrep is given as short time width and as great amplitude as possible in order to reduce the echo spacing (interval between inversion pulses) in the fast spin echo technique. Since the Maxwell term involves a term proportional to the square of the amplitude of a gradient pulse, the effect exerted by the Maxwell term becomes great due to the flow compensating pulse constituted of fcrdep and fcrrep.
  • a bipolar pulse is employed in the slice gradient instead of the read gradient. This prevents the spins flowing in the read direction from being provided with an unnecessary phase. Moreover, the bipolar pulse is incorporated before an inversion pulse applied immediately before the flow compensating pulse. By this, a phase shift having a phase opposite to the phase shift due to the flow compensating pulse can be introduced by the bipolar pulse. Furthermore, the bipolar pulse is made to impart a phase shift equal to the non-linear phase shift due to the flow compensating pulse. This entire process cancels the non-linear phase shift due to the flow compensating pulse, thereby preventing image quality degradation which occurs when the flow compensating pulse is applied.
  • the present invention provides an MR imaging apparatus comprising: pulse sequence creating means for creating a pulse sequence which incorporates a flow compensating pulse in a read gradient of a pulse sequence according to the fast spin echo technique, and incorporates a bipolar pulse in a slice gradient before an inversion pulse applied immediately before the flow compensating pulse, to impart a phase shift equal to a non-linear phase shift due to the flow compensating pulse; data acquisition means for executing the created pulse sequence to acquire data; and image producing means for reconstructing an image from the acquired data.
  • the MR imaging apparatus as described regarding the second aspect can suitably implement the MR imaging method in the first aspect, and MR imaging according to the fast spin echo technique incorporating flow compensation can be conducted in a low magnetic field without image quality degradation.
  • FIG. 1 is a block diagram illustrating an MR imaging apparatus in accordance with one embodiment of the present invention.
  • FIG. 2 is a flow chart illustrating a Maxwell-term correcting pulse sequence creating process in the MR imaging apparatus shown in FIG. 1.
  • FIG. 3 illustrates the meaning of symbols indicating the time width and amplitude of a flow compensating pulse.
  • FIG. 4 illustrates the waveform of a correcting pulse.
  • FIG. 5 illustrates an example of a pulse sequence in accordance with the present invention.
  • FIG. 6 illustrates an example of a pulse sequence for observing the effect of the correcting pulse.
  • FIG. 1 is a block diagram of an MR imaging apparatus in accordance with one embodiment of the present invention.
  • a magnet assembly 1 has a space (bore) in which a subject is inserted. Surrounding the space are disposed a permanent magnet 1p for applying a constant main magnetic field to the subject, a gradient magnetic field coil 1g for generating gradient magnetic fields as the slice, read and encoding gradients, a transmitter coil 1t for applying RF pulses for exciting or inverting spins in atomic nuclei within the subject, and a receiver coil 1r for detecting an NMR signal from the subject.
  • the gradient magnetic field coil 1g, the transmitter coil 1t and the receiver coil 1r are connected to a gradient magnetic field drive circuit 3, an RF power amplifier 4 and a preamplifier 5, respectively.
  • a sequence memory circuit 8 operates the gradient magnetic field drive circuit 3 based on a stored pulse sequence supplied from a computer 7 to generate the gradient magnetic fields from the gradient magnetic field coil 1g in the magnet assembly 1.
  • the sequence memory circuit 8 also operates a gate modulation circuit 9 to modulate a carrier output signal from an RF oscillation circuit 10 into a pulse-like signal having a predetermined timing and envelope shape.
  • the pulse-like signal is supplied to the RF power amplifier 4 as an RF pulse and is power amplified in the RF power amplifier 4.
  • the power-amplified signal is then applied to the transmitter coil 1t in the magnet assembly 1 to selectively excite an imaging region.
  • the preamplifier 5 amplifies an NMR signal detected from the subject at the receiver coil 1r in the magnet assembly 1 and supplies it to a phase detector 12.
  • the phase detector 12 phase-detects the NMR signal supplied from the preamplifier 5 using the carrier output signal from the RF oscillation circuit 10 as a reference signal, and supplies the NMR signal to an A/D (analog-to-digital) converter 11.
  • the A/D converter 11 converts the phase-detected analog signal into a digital signal and supplies it to the computer 7.
  • the computer 7 reads the data from the A/D converter 11 and performs an image reconstruction operation to produce an image of the imaging region.
  • the image is displayed on a display device 6.
  • the computer 7 also performs overall control, including receipt of information input from an operator console 13.
  • the computer 7 moreover creates a pulse sequence based on commands input by the operator and supplies the pulse sequence to the sequence memory circuit 8. Therefore, the computer 7 corresponds to the pulse sequence creating means, the overall system corresponds to the pulse sequence executing means, and the computer 7 corresponds to the image producing means.
  • FIG. 2 is a flow chart illustrating a non-linear phase shift correcting pulse sequence creating process executed in the computer 7. The process is executed subsequent to generation of a pulse sequence according to the fast spin echo technique incorporating a flow compensating pulse in the read direction.
  • Step S1 the amount of a non-linear phase shift ⁇ .sub. ⁇ .sbsb.-- FC1 by the flow compensating pulse constituted of fcrdep and fcrrep is calculated according to the following equation:
  • the slice gradient is in the Y-direction
  • the read gradient is in the X-direction
  • the encoding gradient is in the Z direction
  • the symbols representing the pulse amplitudes and pulse widths of the read gradient are defined as shown in FIG. 3.
  • Step S2 a correcting pulse constituted of gzfcf and gzmfcf which satisfies the equation below is calculated.
  • the pulse amplitude and the pulse width of the correcting pulse gzfcf shown in FIG. 4 are calculated so that the equation below is satisfied.
  • the correcting pulse gzmfcf is symmetrized with the correcting pulse gzfcf. Accordingly, the correcting pulse constituted of gzfcf and gzmfcf forms a bipolar pulse.
  • Step S3 a pulse sequence is created which incorporates the correcting pulse constituted of gzfcf and gzmfcf in the above-mentioned pulse sequence according to the fast spin echo technique incorporating the flow compensating pulse constituted of fcrdep and fcrrep in the read gradient. The process is then terminated.
  • FIG. 5 exemplarily shows the created pulse sequence.
  • the pulse sequence shown incorporates the correcting pulse gzmfcf as an integral part of the fore portion of the slice selective pulse sselect.
  • the non-linear phase shift by the correcting pulse constituted of gzfcf and gzmfcf is inverted by each of the following 180° pulses rf21, rf22, rf23, . . . , and is added in opposite phase to the non-linear phase shift due to the flow compensating pulse constituted of fcrdep and fcrrep, thereby canceling the non-linear phase shift and improving image quality.
  • FIG. 6 shows a pulse sequence for observing the effect of the correcting pulse constituted of gzfcf and gzmfcf.

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nonlinear Science (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Image Processing (AREA)
  • Image Analysis (AREA)
US09/286,256 1998-05-21 1999-04-05 MR imaging method and apparatus Expired - Fee Related US6137289A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10140295A JP3028220B2 (ja) 1998-05-21 1998-05-21 Mri装置
JP10-140295 1998-05-21

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US (1) US6137289A (fr)
EP (1) EP0959366A3 (fr)
JP (1) JP3028220B2 (fr)
KR (1) KR19990088424A (fr)
CN (1) CN1238935A (fr)
BR (1) BR9902095A (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020195977A1 (en) * 2001-06-21 2002-12-26 Takao Goto External magnetic field measuring method, static magnetic field correcting method, external magnetic field measuring apparatus, and MRI system
US20030189425A1 (en) * 2002-04-05 2003-10-09 Patrick Le Roux Method and apparatus for fast imaging by nuclear magnetic resonance
US20080315876A1 (en) * 2007-06-20 2008-12-25 Mitsuharu Miyoshi Magnetic resonance imaging apparatus and magnetic resonance image generating method
WO2018114554A1 (fr) * 2016-12-20 2018-06-28 Koninklijke Philips N.V. Imagerie rm à séparation eau/graisse de type dixon

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100367419B1 (ko) * 2000-01-25 2003-01-10 주식회사 메디슨 K공간을 공유함으로써 FSE기법에 3-포인트 Dixon기법을 적용한 방법
US6486667B1 (en) 2000-03-31 2002-11-26 Koninklijke Philips Electronics N.V. Combination of fluid-attenuated inversion-recovery complex images acquired using magnetic resonance imaging
DE10157540B4 (de) * 2001-11-23 2007-01-11 Siemens Ag Doppelechosequenz und Magnetresonanzgerät zum Ausführen der Doppelechosequenz und Verwendung desselben in der Orthopädie
JP2007090001A (ja) 2005-09-30 2007-04-12 Ge Medical Systems Global Technology Co Llc Mrスキャン方法およびmri装置
US7557575B2 (en) * 2006-04-04 2009-07-07 Kabushiki Kaisha Toshiba Magnetic resonance imaging apparatus and magnetic resonance imaging method
US7567081B2 (en) * 2007-05-03 2009-07-28 University Of Basel Magnetic resonance non-balanced-SSFP method for the detection and imaging of susceptibility related magnetic field distortions
CN105988098B (zh) * 2015-01-30 2021-07-27 Ge医疗系统环球技术有限公司 磁共振信号采集系统及方法
US11510655B2 (en) * 2019-09-10 2022-11-29 GE Precision Healthcare LLC Methods and systems for motion corrected wide-band pulse inversion ultrasonic imaging

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US4683431A (en) * 1985-08-16 1987-07-28 Picker International, Inc. Magnetic resonance imaging of high velocity flows
US5007426A (en) * 1986-11-21 1991-04-16 General Electric Cgr S.A. Method for depiction of moving parts in a body by nuclear magnetic resonance experiment
US5592084A (en) * 1992-12-01 1997-01-07 Picker Nordstar Inc. Method for imaging of movement of material
US5652513A (en) * 1996-08-01 1997-07-29 Picker International, Inc. Phase sensitive magnetic resonance technique with integrated gradient profile and continuous tunable flow

Patent Citations (4)

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Publication number Priority date Publication date Assignee Title
US4683431A (en) * 1985-08-16 1987-07-28 Picker International, Inc. Magnetic resonance imaging of high velocity flows
US5007426A (en) * 1986-11-21 1991-04-16 General Electric Cgr S.A. Method for depiction of moving parts in a body by nuclear magnetic resonance experiment
US5592084A (en) * 1992-12-01 1997-01-07 Picker Nordstar Inc. Method for imaging of movement of material
US5652513A (en) * 1996-08-01 1997-07-29 Picker International, Inc. Phase sensitive magnetic resonance technique with integrated gradient profile and continuous tunable flow

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Title
Shading artifacts in phase contrast angiography induced by maxwell terms; analysis and correction Matt A. Bernstein, et al, source not known, copy attached. *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020195977A1 (en) * 2001-06-21 2002-12-26 Takao Goto External magnetic field measuring method, static magnetic field correcting method, external magnetic field measuring apparatus, and MRI system
US6707301B2 (en) 2001-06-21 2004-03-16 Ge Medical Systems Global Technology Company, Llc External magnetic field measuring method, static magnetic field correcting method, external magnetic field measuring apparatus, and MRI system
US20030189425A1 (en) * 2002-04-05 2003-10-09 Patrick Le Roux Method and apparatus for fast imaging by nuclear magnetic resonance
US6965233B2 (en) * 2002-04-05 2005-11-15 Ge Medical Systems Global Technology Company Llc Method and apparatus for fast imaging by nuclear magnetic resonance
US20080315876A1 (en) * 2007-06-20 2008-12-25 Mitsuharu Miyoshi Magnetic resonance imaging apparatus and magnetic resonance image generating method
US7759934B2 (en) 2007-06-20 2010-07-20 Ge Medical Systems Global Technology Company, Llc Magnetic resonance imaging apparatus and magnetic resonance image generating method
WO2018114554A1 (fr) * 2016-12-20 2018-06-28 Koninklijke Philips N.V. Imagerie rm à séparation eau/graisse de type dixon

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Publication number Publication date
JP3028220B2 (ja) 2000-04-04
CN1238935A (zh) 1999-12-22
JPH11318852A (ja) 1999-11-24
KR19990088424A (ko) 1999-12-27
EP0959366A3 (fr) 2001-07-25
EP0959366A2 (fr) 1999-11-24
BR9902095A (pt) 2000-01-18

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