US5261414A - Blood pressure monitor system - Google Patents

Blood pressure monitor system Download PDF

Info

Publication number
US5261414A
US5261414A US07/901,091 US90109192A US5261414A US 5261414 A US5261414 A US 5261414A US 90109192 A US90109192 A US 90109192A US 5261414 A US5261414 A US 5261414A
Authority
US
United States
Prior art keywords
blood pressure
pulse wave
magnitude
cuff
mean
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
US07/901,091
Other languages
English (en)
Inventor
Ye Aung
Masami Takaya
Hideo Nishibayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Colin Medical Technology Corp
Original Assignee
Colin Electronics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Colin Electronics Co Ltd filed Critical Colin Electronics Co Ltd
Assigned to COLIN ELECTRONICS CO., LTD. reassignment COLIN ELECTRONICS CO., LTD. ASSIGNMENT OF ASSIGNORS INTEREST. Assignors: AUNG, YE, NISHIBAYASHI, HIDEO, TAKAYA, MASAMI
Application granted granted Critical
Publication of US5261414A publication Critical patent/US5261414A/en
Assigned to COLIN MEDICAL TECHNOLOGY CORPORATION reassignment COLIN MEDICAL TECHNOLOGY CORPORATION ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: COLIN ELECTRONICS CO., LTD.
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
    • A61B5/02225—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers using the oscillometric method
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/02108—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
    • A61B5/02116—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics of pulse wave amplitude
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers

Definitions

  • the present invention relates in general to a blood pressure monitor system and in particular to such a monitor system which continuously determines blood pressure values of a living subject, according to a relationship between blood pressure and pulse wave magnitude, based on detected magnitudes of the pulse wave.
  • a blood pressure monitor apparatus of the type which (a) presses a body portion (e.g., upper arm) of a patient by inflating a cuff wound around the upper arm, (b) detects an oscillatory pressure wave transmitted from the upper arm to the cuff in synchronism with heartbeat of the patient, or a start and an end of arterial sounds (i.e., Korotkoff sounds) produced from a brachial artery in the upper arm of the patient, while the air pressure in the inflated cuff is slowly lowered, (c) measures a systolic and a diastolic blood pressure of the subject based on the variation of the oscillatory pressure wave or based on the start and end of the Korotkoff sounds, (d) detects a pressure pulse wave produced from an artery (e.g., radial artery) of the patient by using a semiconductor pressure sensing means, (e) determines a relationship between blood pressure and pulse wave magnitude (hereinafter, abbreviated
  • this apparatus is capable of monitoring the blood pressure of the patient for a long time, without so frequently pressing the upper arm of the patient by inflating the cuff.
  • This apparatus is disclosed in U.S. Pat. No. 4,928,701 assigned to the Assignee of the present application.
  • the BP-PW relationship is determined by solving the simultaneous equations of first degree with two unknowns in which a measured systolic blood pressure is associated with a detected upper-peak (maximum) magnitude of a pulse of the pressure pulse wave and a measured diastolic blood pressure is associated with a detected lower-peak (minimum) magnitude of the same pulse or another pulse.
  • diastolic blood pressure values of a subject measured by using an inflatable cuff suffer from considerably large variance. Since the apparatus determines and updates the BP-PW relationship based on diastolic blood pressure values that may be largely variable, the apparatus may not accurately determine or estimate blood pressure values of the subject.
  • the pulse wave sensor cannot detect the pressure pulse wave from the radial artery and therefore the apparatus cannot monitor the blood pressure of the patient, during the periods of measurement of systolic and diastolic blood pressure values using the cuff, because the blood flow from the brachial artery to the radial artery is blocked by the inflated cuff.
  • a blood pressure monitor system for monitoring blood pressure of a living subject, comprising (a) pulse wave detecting means for detecting a first pulse wave produced from an artery of the subject via a body surface of the subject over the artery, (b) an inflatable cuff for pressing a body portion of the subject, (c) blood pressure measuring means for measuring a systolic and a mean blood pressure of the subject based on variation in amplitude of pulses of a second pulse wave transmitted to the cuff by changing a pressure in the cuff, and a blood pressure determining means for determining a relationship between blood pressure and pulse wave magnitude based on the systolic and mean blood pressure values measured by the blood pressure measuring means and an upper-peak magnitude and a mean magnitude of the first pulse wave detected by the pulse wave detecting means, and continuously determining, according to the relationship, blood pressure values of the subject based on magnitudes of the first pulse wave detected by the pulse wave detecting means.
  • the blood pressure determining means determines a relationship between blood pressure and pulse wave magnitude, based on the systolic and mean blood pressure values measured by the blood pressure measuring means and the upper-peak and mean magnitudes of the first pulse wave detected by the pulse wave detecting means, and continuously determines, according to the thus determined relationship, blood pressure values of the subject based on magnitudes of the first pulse wave detected by the pulse wave detecting means.
  • the present monitor system continuously monitors the blood pressure of the subject.
  • Mean blood pressure values measured by using the cuff do not vary, therefore are stable and reliable. Since the reliable means blood pressure values are utilized for determining the BP-PW relationship, the present monitor system provides blood pressure values of high accuracy.
  • the blood pressure measuring means determines the systolic and mean blood pressure values based on the amplitude variation of respective pulses of the second pulse wave transmitted to the cuff by changing the pressure in the cuff.
  • This blood pressure measurement method is so-called "oscillometric" method.
  • the oscillometric method permits a mean blood pressure to be measured before a diastolic blood pressure is measured.
  • the monitor system can terminate the blood pressure measurement, without further lowering the cuff pressure to a level equal to a diastolic blood pressure, therefore, even where the cuff and the pulse wave detecting means are set on the same limb of the subject, the present system shortens the periods of interruption of the continuous blood pressure monitoring due to the blood pressure measurements using the cuff.
  • the blood pressure measuring means calculates a difference between the amplitudes of each pair of time-wise adjacent two pulses out of the respective pulses of the second pulse wave and determines as the systolic blood pressure of the subject a pressure in the cuff when the differences between the amplitudes of the pairs of pulses become maximum, and subsequently determines as the mean blood pressure of the subject a pressure in the cuff when the amplitudes of the respective pulses of the second pulse wave become maximum.
  • the pulse wave detecting means includes at least one pressure sensor each of which detects the first pulse wave transmitted thereto from the artery of the subject via the body surface of the subject, and produces an electric signal indicative of the detected first pulse wave, the detecting means defining a variable line indicative of a magnitude of the electric signal, and determining, as a mean magnitude of one pulse of the first pulse wave, a magnitude of the electric signal indicated by the variable line when a first area bounded by the variable line and an upper portion of the electric signal corresponding to the one pulse which portion is positioned above the variable line, is equal to a second area bounded by the variable line and a lower portion of the electric signal corresponding to the one pulse which portion is positioned beneath the variable line.
  • the detecting means may define a first and a second line each indicative of a magnitude of the electric signal and determine, as a mean magnitude of one pulse of the first pulse wave, a magnitude of the electric signal indicated by the first line which passes bary-centric coordinates of an area bounded by the electric signal corresponding to the one pulse and the second line passing a lower-peak point of the one pulse.
  • the blood pressure determining means determines as the relationship the following linear function:
  • the blood pressure determining means determining the constants ⁇ , ⁇ by solving the following simultaneous equations with the two unknowns ⁇ , ⁇ :
  • P sys the systolic blood pressure
  • ST mean the mean magnitude of said first pulse wave.
  • the blood pressure determining means successively calculates a systolic and diastolic blood pressure values of the subject, according to the relationship, based on an upper-peak and a lower-peak magnitude of each of pulses of the first pulse wave detected by the pulse wave detecting means after the relationship is determined.
  • the blood pressure determining means updates the relationship at predetermined intervals of time, based on pairs of systolic and mean blood pressure values measured by the blood pressure measuring means at the predetermined intervals.
  • the monitor system further comprises display means for successively displaying, along a time axis, the blood pressure values determined by the blood pressure determining means.
  • the pulse wave detecting means comprises a sensor chip including a semiconductor substrate and a plurality of pressure sensing elements formed in one of opposite surfaces of the substrate, and pressing means for pressing the sensor chip against the artery via the body surface so as to partially flatten a wall of the artery, so that each of the pressure sensing elements detects the first pulse wave transmitted to the one surface of the substrate from inside the artery via the flattened wall of the artery and the body surface over the artery.
  • FIG. 1 is a diagrammatic view of a blood pressure monitor system embodying the present invention
  • FIG. 2 is a side view of a pulse wave sensor probe of the monitor system of FIG. 1;
  • FIG. 3 is a plan view of the pulse wave sensor probe of FIG. 2;
  • FIG. 4 is a perspective view of a semiconductor pulse wave sensor chip employed in the sensor probe of FIG. 2;
  • FIG. 5 is a flow chart representing the blood pressure monitor operation of the monitor system of FIG. 1;
  • FIG. 6 is a graph for illustrating the manner of determining a mean magnitude, ST mean , of a pulse of the pulse wave in Step S11 of the flow chart of FIG. 5;
  • FIG. 7 is a graph for illustrating a time-wise varying trend of the blood pressure of a subject displayed on a display device of the monitor system of FIG. 1 as a result of carrying out the flow chart of FIG. 5.
  • reference numeral 10 designates a bag-like, inflatable cuff formed of rubber.
  • the cuff 10 is worn on a living body such as a patient by being wound around, for example, an upper arm of the patient.
  • a pressure sensor 14, a selector valve 16, and an air pump 18 are connected to the cuff 10 via flexible piping 12.
  • the pressure sensor 14 detects the air pressure in the cuff 10 (hereinafter, referred to as the "cuff pressure"), and supplies an electric signal, SP, representative of the detected cuff pressure, to a band-pass filter 20 and a low-pass filter 21.
  • the band-pass filter 20 has a specific band of frequencies corresponding to the frequency of an oscillatory component ("Alternating Current (AC)" component) of the pressure signal SP produced in synchronism with heartbeat of the patient, and transmits only the oscillatory signal component.
  • the oscillatory signal component is referred to as the "cuff pulse wave signal SM”.
  • the cuff pulse wave signal SM is representative of the oscillatory pressure wave (i.e., pulse wave) transmitted from the upper arm to the cuff 10 in synchronism with the heartbeat of the patient, when the cuff pressure is slowly lowered.
  • the band-pass filter 20 separates the cuff pulse wave signal SM from the pressure signal SP and supplies the signal SM to a central processing unit (CPU) 24 via a first analog to digital (A/D) converter 22.
  • the low-pass filter 21 is a high-frequency cutting filter that cuts off high-frequency components from the pressure signal SP. Stated differently, the low-pass filter 21 transmits only a static-pressure signal component ("Direct Current (DC)" component) of the pressure signal SP.
  • the static-pressure signal component is referred to as the "cuff pressure signal SK".
  • the cuff pressure signal SK is representative of a static pressure, P, of the cuff 10 (hereinafter, referred to as the "cuff static pressure P").
  • the cuff pressure signal SK is supplied to the CPU 24 via the first A/D converter 26.
  • the selector valve 16 is selectively placed in an INFLATION position, a SLOW-DEFLATION position, and a QUICK-DEFLATION position.
  • a slow- and a quick-deflation outlet 16a, 16b of the selector valve 16 both are closed so that pressurized air is supplied from the air pump 18 to the cuff 10 until the cuff static pressure P is increased to a predetermined target pressure level;
  • the slow-deflation outlet 16a of the valve 16 is opened so that the pressurized air is slowly discharged from the cuff 10 to the atmosphere at a predetermined rate suitable for blood pressure measurement; and, immediately after the blood pressure measurement terminates during the slow-deflation of the cuff 10, the quick-deflation outlet 16b of the selector valve 16 is opened and thereby the selector valve 16 is placed in the QUICK-DEFLATION position, so that the pressurized air is quickly discharged from the cuff 10 to the atmosphere through the opened
  • the CPU 24 is connected via data bus to a read only memory (ROM) 26, a random access memory (RAM) 28, and an input and output (I/0) interface 27.
  • the CPU 24 processes supplied signals according to control programs pre-stored in the ROM by utilizing the temporary-storage function of the RAM.
  • the CPU 24 supplies an ON/OFF signal to a drive circuit 31 connected to the air pump 18 and thereby regulates the supply of electric power to the air pump 18.
  • the CPU 24 controls the start and stop of the operation of the air pump 18.
  • the CPU 24 supplies a switch signal to switch the positions of the selector valve 16 and thereby regulates the cuff static pressure P as described above.
  • the CPU 24 carries out a series of steps for blood pressure measurement according to the control program pre-stored in the ROM 26, and determines a systolic blood pressure value, P sys , and a mean blood pressure value, P mean , of the patient, based on the cuff pulse wave signal SM and the cuff pressure signal SK.
  • the CPU 24 commands a display 29 to display the measured blood pressure values P sys , P mean .
  • This control program is described in JIS (Japanese Industrial Standard) T 1115, and a well-known algorithm used as the "oscillometric" blood pressure measurement method.
  • the CPU 24 While the cuff static pressure P is slowly decreased from a predetermined pressure level sufficiently higher than an estimated systolic blood pressure of the patient, the CPU 24 reads in the cuff pulse wave signal SM and the cuff static pressure signal SK.
  • the CPU 24 determines as a systolic blood pressure P sys a cuff static pressure P at the time when the amplitudes of respective pulses of the signal SM significantly largely varies, for example, when the rate of change of the amplitudes becomes maximum, and determines as a mean blood pressure P mean a cuff static pressure P at the time when the amplitudes of respective pulses of the signal SM become maximum.
  • the present monitor system further includes a pulse wave sensor probe 32 which is worn on an arm of the patient.
  • the sensor probe 32 serves as pulse wave detecting means.
  • the sensor probe 32 is detachably set on a wrist of the patient with a pair of bands 36, 36 fastened around the wrist.
  • the bands 36, 36 are provided with a pair of fasteners, respectively.
  • a radial artery 35 located above a radius bone in the wrist is easy to detect pressure pulse wave therefrom.
  • the sensor probe 32 detects the pressure pulse wave from the radial artery, and supplies a pressure pulse wave signal, ST, representing the detected pressure pulse wave, to the CPU 24 via a second A/D converter 34.
  • a clock signal generator 38 supplies a clock signal, CK, to the CPU 24 at a predetermined frequency.
  • the sensor probe 32 includes a housing 40 consisting of a first and a second housing 42, 46 which are pivotally connected to each other by a pin 44.
  • the housing 40 as a whole has a container-like configuration.
  • the first housing 42 has an open end which is adapted to contact a body surface or skin 43 of the wrist.
  • a container-like casing 48 is accommodated in the first housing 42.
  • the casing 48 has an open end which is opposed to the skin 43 when the sensor probe 32 is set on the skin 43.
  • the casing 48 has a pair of opposite arms 50, 52 which respectively engage a pair of guide grooves (not shown) formed with the first housing 42.
  • the casing 48 is also engaged with a feed screw (not show) extending along the longitudinal side of the housing 40, i.e., in a direction generally perpendicular to the direction of extension of the radial artery 35.
  • a feed screw (not show) extending along the longitudinal side of the housing 40, i.e., in a direction generally perpendicular to the direction of extension of the radial artery 35.
  • the first housing 42 also accommodates a reduction gear unit (not shown) which is on one hand operatively connected to one of opposite axial ends of the feed screw located on the side of the second housing 46 and which is on the other hand operatively connected to an output shaft of the above-indicated electric motor via a flexible coupling (not shown).
  • This arrangement ensures that the driving force of the electric motor is transmitted to the feed screw via the reduction gear unit irrespective of the relative angular position between the first and second housings 42, 46.
  • An elastic diaphragm 54 is supported by an inner wall of the casing 48, so that the diaphragm 54 and the casing 48 cooperate with each other to define a pressure chamber (not shown) on the side of a bottom wall of the casing 48.
  • a semiconductor pressure sensor chip 60 is secured to an external surface of the diaphragm 54 away from the pressure chamber.
  • the sensor chip 60 has, in a press surface 56 thereof, an array of pressure sensing elements 58 arranged in the direction of movement of the casing 48.
  • the sensor chip 60 When pressurized air is supplied to the pressure chamber and the chamber pressure is raised to about 10 to 100 mmHg, the sensor chip 60 is advanced out of the casing 48 and first housing 42, so that the sensor chip 60 is pressed against the radial artery 35 in such a manner that the wall of the artery 35 is partially flattened.
  • FIG. 4 shows the pressure sensor chip 60.
  • the sensor chip 60 consists of a back-up plate 64 formed of a rigid material such as glass and a semiconductor substrate 66 such as a monocrystalline silicon plate.
  • the semiconductor substrate 66 is adhered to one surface of the back-up plate 64.
  • the semiconductor substrate 66 has a thickness of about 300 microns, and has an elongate recess (not shown) formed in one of opposite surfaces on the side of the back-up plate 64.
  • the semiconductor substrate 66 includes a diaphragm portion 68 having a reduced thickness of about several to ten and several microns.
  • An array of pressure sensing elements 58 are formed in the diaphragm portion 68 at predetermined intervals of distance (e.g., about 200 microns) along the longitudinal direction of the sensor chip 60.
  • Each pressure sensing element 58 is constituted by a resistance bridge consisting of four resistance elements provided by a well-known semiconductor production process such as impurity diffusion or injection. Additional description of this sensor chip 60 is provided in U.S. Pat. No. 5,101,829 assigned to the Assignee of the present application.
  • Each pressure sensing element 58 detects strain or pressure variation (i.e., pressure pulse wave) applied to the press surface 56 (or diaphragm portion 68) of the sensor ship 60 and provides as a pulse wave signal ST an electric signal indicative of the detected pressure variation.
  • the sensor chip 60 is pressed against the radial artery 35 via the skin 43 in such a manner that the array of pressure sensing elements 58 are located above the artery 35 and extends in the direction generally perpendicular to the artery 35.
  • each pressure sensing element 58 produces a pulse wave signal ST indicative of the pressure pulse wave transmitted from inside the artery 35 to the press surface 56 via the flattened wall of the artery 35 and the skin 43 located between the flattened wall of the artery 35 and the press surface 56.
  • a control device (not shown) operates, based on the pressure pulse wave signals ST from the individual pressure sensing elements 58, for actuating the above-mentioned electric motor to displace the casing 48 to an optimum position on the skin 43 where the pressure sensing elements 58 are positioned above the radial artery 35.
  • the control device determines an optimum pressure to be applied to the pressure chamber of the casing 48, that is, optimum pressing force to be applied to the sensor chip 60 to press the artery 35 to partially flatten the wall of the artery 35.
  • Step S1 the control of the CPU 24 proceeds with Step S1 to judge whether or not a START switch not shown) has been turned ON, that is, whether or not a monitor-start signal is supplied to, and present at, the CPU 24.
  • the START switch is turned ON after the cuff 10 is wound around the upper arm of a patient and the pulse wave sensor probe 32 is worn on the wrist of the arm of the patient.
  • Step S2 the control of the CPU 24 goes to Step S2 to clear the contents of a timer T provided in the RAM 28, that is, reset the timer T to zero.
  • the timer T measures time by counting and registering the number of clock signals CK supplied from the clock signal generator 38. The contents of the timer T are used by the CPU 24 for judging whether or not to calibrate the monitor system. After being reset to zero, the timer T starts counting the clock signals CK supplied thereto.
  • Step S2 is followed by Step S3 to switch the selector valve 16 to the INFLATION position and actuates the air pump 18 to supply pressurized air to the cuff 10.
  • the cuff static pressure P represented by the cuff static pressure signal SK
  • Step S3 is followed by Step S4 to judge whether or not the cuff static pressure P has exceeded a predetermined target pressure level P 1 .
  • the target pressure level P 1 is pre-determined to be higher (e.g., about 180 mmHg) than an estimated systolic blood pressure of the patient.
  • Step S6 is carried out to judge, based on the cuff pulse wave signal SM, whether or not one pulse of the cuff pulse wave signal SM corresponding to one heartbeat of the patient has been supplied from the band-pass filter 20. If a negative judgement (NO) is made in Step S6, the CPU 24 waits, that is, repeats Step S6.
  • Step S6 the control of the CPU 24 goes to Step S7 to determine an amplitude of that one pulse by subtracting a lower-peak magnitude of the pulse from an upper-peak magnitude of the same pulse, and store the determined amplitude together with a cuff static pressure P at the time of occurrence of that one pulse.
  • Step S8 the control of the CPU 24 goes to Step S8 to carry out the blood pressure determine routine in which a systolic and a mean blood pressure are determined based on variation of the amplitudes of the respective pulses of the cuff pulse wave signal SM which has been supplied to the CPU 24 up to the current time during the cuff slow-deflation process.
  • the CPU 24 determines, as an actual or standard systolic blood pressure P sys , a cuff static pressure P at the time when the amplitudes of the respective pulses significantly largely change, that is, when the differences between pairs of time-wise adjacent two amplitudes of respective pulses of the cuff pulse wave signal SM become maximum.
  • This time corresponds to the time when the rate of change of the amplitudes of the pulses becomes maximum.
  • the CPU 24 determines, as an actual or standard mean blood pressure P mean , a cuff static pressure P at the time when the amplitudes of the respective pulses become maximum, that is, at the time of occurrence of one of the pulses which has a maximum amplitude of all the amplitudes of other pulses.
  • the thus determined systolic and mean blood pressure values P sys , P mean are stored in the RAM 28.
  • Step S8 is followed by Step S9 to judge whether or not the systolic and mean blood pressure values P sys , P mean have been determined in Step S8.
  • Step S9 the CPU 24 repeats Steps S6 to S8.
  • Step S9 the control of the CPU 24 goes to Step S10 to switch the selector valve 16 from the SLOW-DEFLATION position to the QUICK-DEFLATION position, thereby causing the cuff 10 to quickly be deflated.
  • Step S11 the CPU 24 determines a relationship between blood pressure and pulse wave magnitude (BP-PW relationship), based on the systolic and mean blood pressure values P sys , P mean determined in Step S8 and the pressure pulse wave signal ST supplied from the optimum pressure sensing element 58 located directly above the radial artery 35.
  • BP-PW relationship blood pressure and pulse wave magnitude
  • the CPU 24 determines an upper-peak (maximum) magnitude, ST max , of a pulse of the signal ST which pulse is detected at the time when the rate of change of the amplitudes of the pulses of the signal SM becomes maximum, that is, when the cuff static pressure P is equal to the systolic blood pressure value P sys , and a mean magnitude, ST mean , of a pulse of the signal ST which pulse is detected at the time when the amplitudes of the pulses of the signal ST become maximum, that is, when the cuff static pressure P is equal to the mean blood pressure value P mean .
  • FIG. 6 shows the manner of determining a mean magnitude ST mean of a pulse of the pressure pulse wave signal ST.
  • the CPU 24 determines as the mean pulse magnitude ST mean a signal magnitude indicated by a line, L, when an area, Su, bounded by the line L and an upper portion of the one-pulse signal ST above the line L is equal to an area, Sd, bounded by the line L and a lower portion of the one-pulse signal ST beneath the line L.
  • the constants ⁇ , ⁇ are determined by solving the following simultaneous equations of first order with the two unknowns ⁇ , ⁇ :
  • the BP-PW relationship may be approximated by a quadratic or higher-order function which satisfies the two pairs of coordinates (T max , P sys ) and (T mean , P mean ).
  • the CPU 24 may be adapted to determine as the mean magnitude ST mean a signal magnitude indicated by a line passing the bary-centric coordinates of an area bounded by the one-pulse signal ST and a line passing a lower-peak point of the one pulse.
  • Step S11 the control of the CPU 24 goes to Step S12 to whether or not one pulse of the pressure pulse wave signal ST has been supplied from the optimum pressure sensing element 58 directly above the radial artery 35. If an affirmative judgement is made in Step S12, the control goes to Step S13 to determine the upper-peak and lower-peak magnitudes, ST max and ST min , of that pulse.
  • Step S13 is followed by Step S14 to estimate a systolic and a diastolic blood pressure, P sys (es) and P dia (es), according to the BP-PW relationship expressed by the above-indicated linear function (1), based on the upper-peak and lower-peak magnitudes ST max and ST min determined in Step S13.
  • each of the values P sys (es) and P dia (es) is calculated as the variable y by replacing the variable x with a corresponding one of the values ST max and ST min .
  • Step S15 the control of the CPU 24 goes to Step S15 to supply a display signal to the display 29 so as to indicate, on a cathode ray tube (CRT) thereof, the thus determined systolic and diastolic blood pressure values P sys (es) and P dia (es).
  • FIG. 7 shows a time-wise varying trend of the blood pressure of the patient, indicated in the graph provided on the display 29.
  • the top and bottom ends, A and B, of each bar 70 correspond to the systolic and diastolic blood pressure values of the patient.
  • the display 29 continuously or successively displays the bars 70 each of which corresponds to one heartbeat of the patient.
  • Step S15 is followed by Step S16 to judge whether or not the START switch has been turned OFF to stop the operation of the present monitor system, that is, whether or not a monitor-stop signal is present at the CPU 24. If an affirmative judgement is made in Step S16, the control of the CPU 24 goes back to Step S1. On the other hand, if a negative judgement is made in Step S16, the control goes to Step S17 to judge whether or not the contents of the timer T have exceeded a reference value, T o , indicative of a pre-determined interval of time employed for periodically calibrating the monitor system, that is, updating the BP-PW relationship.
  • the reference time T o is pre-determined at 10 to 20 minutes.
  • Step S17 Short after the initiation of the monitoring operation, a negative judgement is made in Step S17, and the CPU 24 repeats Steps S12 to S17. Consequently, the display 29 continues to display successive bars 70 each indicative of estimated blood pressure values of the patient. Meanwhile, when the contents of the timer T are increased up to the reference value T o and accordingly an affirmative judgement is made in Step S17, the control of the CPU 24 goes back to Step S2 and the following steps.
  • Step S8 another pair of standard systolic and mean blood pressure values P sys , P mean are determined and, in Step S11, another BP-PW relationship is determined based on the thus determined values P sys , P mean and an upper-peak and a mean magnitude of the signal ST detected when the cuff static pressure P is equal to the systolic or mean blood pressure P sys , P mean , respectively.
  • the BP-PW relationship is updated by replacing the previous one with the newly determined one.
  • the CPU 24 continuously estimates systolic and diastolic blood pressure values P sys (es), P dia (es) of the patient based on the upper-peak and lower-peak magnitudes ST max , ST min of each of respective pulses of the pressure pulse wave signal ST read in after the BP-PW relationship is updated.
  • the pairs of values P sys (es), P dia (es) are successively displayed as respective bars 70 on the display 29.
  • the pressure sensor 14, air pump 18, filters 20, 21, Step S8, a portion of the CPU 24, ROM 26 and RAM 28 for carrying out Step S8, and others cooperate with each other to serve as blood pressure measuring means for measuring actual or standard systolic and mean blood pressure values of a living subject by varying the cuff static pressure P;
  • the pulse wave sensor probe 32 serves as pulse wave detecting means;
  • Steps S11 to S14 and a portion of the CPU 24, ROM 26 and RAM 28 for carrying out Steps S11 to S14 cooperate with each other to serve as blood pressure determining means for determining a BP-PW relationship based on the systolic and mean blood pressure values P sys , P mean measured by the blood pressure measuring means and an upper-peak magnitude and a mean magnitude of the pressure pulse wave signal ST supplied from the pulse wave detecting means, and continuously determining, according to the BP-PW relationship, blood pressure values of the subject based on magnitudes of the pressure pulse wave actually detected by the pulse wave detecting means.
  • the present monitor
  • the BP-PW relationship is determined and updated by utilizing mean blood pressure values P mean that are more reliable than diastolic blood pressure values P dia involving a considerably large variance.
  • P mean mean blood pressure values
  • P dia diastolic blood pressure values
  • Step S8 the CPU 24 can terminate the blood pressure measurement immediately after the cuff static pressure P is lowered down to a mean blood pressure P mean of the patient, since the systolic and mean blood pressure measurement is carried out by the oscillometric method.
  • the present monitor system reduces the time required for carrying out the blood pressure measurement, in comparison with the measurement time for the case where diastolic blood pressure values are used for determining and updating the BP-PW relationship.
  • the monitor system advantageously shortens each period of interruption of the blood pressure monitoring due to the blocking of the blood flow under the cuff 10 inflated for measurement of the actual blood pressure values.
  • the pulse wave sensor probe 32 is adapted to detect the pressure pulse wave from the radial artery 35 in the wrist of a subject, it is possible to adapt the sensor probe 32 to detect the pressure pulse wave from other arteries, such as a carotid artery and a pedal dosal artery, located near the body surface of the subject from which the pressure pulse wave is easily detected.
  • the pulse wave sensor chip 60 including a plurality of pressure sensing elements 58 is used, it is possible to employ for the detection of pressure pulse wave a pressure sensor having a single point or location of detection.
  • the pressure pulse wave detecting means may be constituted by a small-volume flexible rubber bag which is used by being wound around a limb of a subject and held at a constant pressure, and a pressure sensor provided inside the rubber bag to detect as the pressure pulse wave the pressure variation inside the rubber bag.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Physiology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
US07/901,091 1991-06-28 1992-06-19 Blood pressure monitor system Expired - Fee Related US5261414A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3185687A JPH053858A (ja) 1991-06-28 1991-06-28 血圧モニタ装置
JP3-185687 1991-06-28

Publications (1)

Publication Number Publication Date
US5261414A true US5261414A (en) 1993-11-16

Family

ID=16175112

Family Applications (1)

Application Number Title Priority Date Filing Date
US07/901,091 Expired - Fee Related US5261414A (en) 1991-06-28 1992-06-19 Blood pressure monitor system

Country Status (5)

Country Link
US (1) US5261414A (de)
JP (1) JPH053858A (de)
DE (1) DE4220532A1 (de)
FR (1) FR2678157B1 (de)
GB (1) GB2257529B (de)

Cited By (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996011628A1 (fr) * 1994-10-12 1996-04-25 Tovarischestvo S Ogranichennoi Otvetstvennostju 'russky Tsentr Perspektivnykh Tekhnology' (Russintsentr' Procede oscillometrique de determination des parametres haemodynamique de base dans la circulation arterielle d'un patient et systeme de mesure de mise en oeuvre dudit procede
US5522395A (en) * 1991-05-01 1996-06-04 Omron Corporation Electronic sphygmomanometer and method of controlling operation of same
WO1997003606A1 (en) * 1992-06-04 1997-02-06 Jackson Sandra R Blood pressure measurement device and method
US5640964A (en) * 1995-02-16 1997-06-24 Medwave, Inc. Wrist mounted blood pressure sensor
US5738104A (en) * 1995-11-08 1998-04-14 Salutron, Inc. EKG based heart rate monitor
US5743857A (en) * 1995-01-17 1998-04-28 Colin Corporation Blood pressure monitor apparatus
US5762610A (en) * 1996-07-03 1998-06-09 Colin Corporation Pressure pulse wave detecting apparatus
US5797850A (en) * 1993-11-09 1998-08-25 Medwave, Inc. Method and apparatus for calculating blood pressure of an artery
ES2123439A1 (es) * 1996-10-30 1999-01-01 Univ Catalunya Politecnica Instrumento para medir la presion sanguinea arterial de forma no invasiva.
US5941828A (en) * 1993-11-09 1999-08-24 Medwave, Inc. Hand-held non-invasive blood pressure measurement device
EP1050267A1 (de) * 1999-05-06 2000-11-08 Colin Corporation Blutdruckmessgerät der oberen und unteren Glieder
EP1053714A2 (de) * 1999-05-17 2000-11-22 Colin Corporation Blutdruckmessgerät der oberen und unteren Glieder
EP1074216A1 (de) * 1999-02-22 2001-02-07 Seiko Epson Corporation Blutdruckmessungsvorrichtung und vorrichtung zum nachweis von pulswellen
US6371921B1 (en) 1994-04-15 2002-04-16 Masimo Corporation System and method of determining whether to recalibrate a blood pressure monitor
US6413224B1 (en) * 1994-02-25 2002-07-02 Colin Corporation Blood pressure measuring apparatus
US20030092999A1 (en) * 1996-10-24 2003-05-15 Colin Corporation Blood pressure monitor
US6565515B2 (en) 1999-05-06 2003-05-20 Colin Corporation Pulse-wave-propagation-velocity-relating-information obtaining apparatus and blood-pressure-index measuring apparatus
US20030130578A1 (en) * 2002-01-09 2003-07-10 Colin Corporation Arteriosclerosis evaluating apparatus
EP1336374A1 (de) * 2002-02-18 2003-08-20 Colin Corporation Druckpulswellenmessgerät
US6632181B2 (en) 1996-06-26 2003-10-14 Masimo Corporation Rapid non-invasive blood pressure measuring device
US20030236465A1 (en) * 2002-06-20 2003-12-25 Colin Corporation Blood-pressure determining apparatus
US20040059234A1 (en) * 2002-08-01 2004-03-25 Martin Gregory J. Method and apparatus for control of non-invasive parameter measurements
US20040225224A1 (en) * 2003-05-05 2004-11-11 Tseng Daniel C.M. Integrated inflating and quick releasing device for electronic sphygmomanometer
US20040243009A1 (en) * 2003-05-30 2004-12-02 Casio Computer Co., Ltd. Wrist-worn high-accuracy pulsation measuring apparatus
EP1491136A1 (de) * 2002-03-28 2004-12-29 Omron Corporation Elektronischer hämomanometer und blutdruckmessverfahren mit einem elektronischen hämomanometer
US20050283082A1 (en) * 2004-06-21 2005-12-22 Geddes Leslie A Optical noninvasive vital sign monitor
US7014611B1 (en) * 2004-06-24 2006-03-21 Purdue Research Foundation Oscillometric noninvasive blood pressure monitor
EP1715429A1 (de) * 2005-04-22 2006-10-25 Fukuda Denshi Co., Ltd. Gerät und Methode um Bioinformation, speziell Blutdruck und Pulswelle, anzuzeigen
US20070287925A1 (en) * 2006-05-13 2007-12-13 Katayama Andrew S Continuous positioning apparatus and methods
US20080045846A1 (en) * 2006-08-16 2008-02-21 Friedman Bruce A Method and system of determining nibp target inflation pressure using an sp02 plethysmograph signal
US20080064968A1 (en) * 2002-08-01 2008-03-13 Martin Gregory J Method and apparatus for control of non-invasive parameter measurements
US20100249616A1 (en) * 2009-03-26 2010-09-30 The General Electric Company Nibp target inflation pressure automation using derived spo2 signals
US7946994B2 (en) 2004-10-07 2011-05-24 Tensys Medical, Inc. Compact apparatus and methods for non-invasively measuring hemodynamic parameters
US20170181648A1 (en) * 2014-02-13 2017-06-29 Nec Corporation Blood pressure estimation device, blood pressure estimation method, blood pressure measurement device, and recording medium
US10952675B2 (en) 2007-10-12 2021-03-23 Shangyi Medical Technology (Hangzhou) Co., Ltd Apparatus and methods for non-invasively measuring a patient's arterial blood pressure
US11083385B2 (en) * 2015-01-26 2021-08-10 University Of Ulsan Foundation For Industry Cooperation Apparatus for measuring blood circulation disorders, and method therefor

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5560366A (en) * 1993-11-29 1996-10-01 Colin Corporation Oscillometric blood pressure measuring apparatus
US5497779A (en) * 1994-03-08 1996-03-12 Colin Corporation Pulse wave detecting apparatus
DE69416667T2 (de) * 1994-03-09 1999-10-14 Colin Corp. Puls-Wellen-Messgerät
US5595180A (en) * 1994-08-10 1997-01-21 Colin Corporation Method and apparatus for winding cuff in blood pressure measurement
DE29511738U1 (de) 1995-07-20 1995-09-28 Yeh, Michael, Taipeh/T'ai-pei Elektronisches Sphygmomanometer
JP4502537B2 (ja) * 2001-03-28 2010-07-14 大阪瓦斯株式会社 浴槽血圧計
JP5732692B2 (ja) * 2010-08-02 2015-06-10 セイコーエプソン株式会社 血圧検出装置及び血圧検出方法
JP5599370B2 (ja) * 2010-10-18 2014-10-01 由久 山崎 静脈環流制限状態設定装置
JP5750805B2 (ja) * 2011-12-27 2015-07-22 国立大学法人東北大学 連続血圧測定システム、連続血圧測定方法、連続血圧測定プログラムおよび、連続血圧測定プログラムを記録したコンピュータ読み取り可能な記録媒体
CN104027102B (zh) * 2014-06-16 2016-06-22 广西科技大学 一种多功能腕式电子血压计

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4360029A (en) * 1978-04-10 1982-11-23 Johnson & Johnson Automatic mean blood pressure reading device
US4427013A (en) * 1981-01-29 1984-01-24 C.R. Bard, Inc. Apparatus and method for measuring blood pressure
EP0152848A2 (de) * 1984-02-17 1985-08-28 Cortronic Corporation Verfahren zur Bestimmung des Druckes einer durch ein flexibles Rohr fliessenden pulsierenden Flüssigkeit und Gerät zur Bestimmung des arteriellen Blutdruckes einer Person
EP0154995A2 (de) * 1984-03-13 1985-09-18 Omron Tateisi Electronics Co. Blutdruckmessgerät
WO1988004910A1 (en) * 1986-12-25 1988-07-14 Nippon Colin Co., Ltd. Blood pressure monitoring system
WO1989009017A1 (en) * 1988-03-24 1989-10-05 Chio Shiu Shin Cardiovascular pressure and condition method and apparatus
US4928701A (en) * 1988-02-23 1990-05-29 Colin Electronics Co., Ltd. Method and apparatus for monitoring blood pressure
US5101829A (en) * 1990-01-09 1992-04-07 Colin Electronics Co., Ltd. Semiconductor pressure pulse wave sensor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4729383A (en) * 1984-12-07 1988-03-08 Susi Roger E Method and apparatus for automatically determining blood pressure measurements
US4727884A (en) * 1986-05-28 1988-03-01 Link William T Technique for obtaining the mean blood pressure constant for an individual's blood pressure
US4987900A (en) * 1987-04-21 1991-01-29 Colin Electronics Co., Ltd. Apparatus for positioning transducer for blood pressure monitor
JPH0428562Y2 (de) * 1988-02-23 1992-07-10
JP2664926B2 (ja) * 1988-03-23 1997-10-22 コーリン電子株式会社 血圧測定装置

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4360029A (en) * 1978-04-10 1982-11-23 Johnson & Johnson Automatic mean blood pressure reading device
US4427013A (en) * 1981-01-29 1984-01-24 C.R. Bard, Inc. Apparatus and method for measuring blood pressure
EP0152848A2 (de) * 1984-02-17 1985-08-28 Cortronic Corporation Verfahren zur Bestimmung des Druckes einer durch ein flexibles Rohr fliessenden pulsierenden Flüssigkeit und Gerät zur Bestimmung des arteriellen Blutdruckes einer Person
EP0154995A2 (de) * 1984-03-13 1985-09-18 Omron Tateisi Electronics Co. Blutdruckmessgerät
WO1988004910A1 (en) * 1986-12-25 1988-07-14 Nippon Colin Co., Ltd. Blood pressure monitoring system
EP0297146B1 (de) * 1986-12-25 1993-10-06 Colin Electronics Co., Ltd. Blutdruckregelungssystem
US4928701A (en) * 1988-02-23 1990-05-29 Colin Electronics Co., Ltd. Method and apparatus for monitoring blood pressure
WO1989009017A1 (en) * 1988-03-24 1989-10-05 Chio Shiu Shin Cardiovascular pressure and condition method and apparatus
US5101829A (en) * 1990-01-09 1992-04-07 Colin Electronics Co., Ltd. Semiconductor pressure pulse wave sensor

Cited By (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5522395A (en) * 1991-05-01 1996-06-04 Omron Corporation Electronic sphygmomanometer and method of controlling operation of same
WO1997003606A1 (en) * 1992-06-04 1997-02-06 Jackson Sandra R Blood pressure measurement device and method
US20030208127A1 (en) * 1993-11-09 2003-11-06 Medwave, Inc. Method and apparatus for calculating blood pressure of an artery
US6589185B1 (en) 1993-11-09 2003-07-08 Medwave, Inc. Method and apparatus for calculating blood pressure of an artery
US5797850A (en) * 1993-11-09 1998-08-25 Medwave, Inc. Method and apparatus for calculating blood pressure of an artery
US5941828A (en) * 1993-11-09 1999-08-24 Medwave, Inc. Hand-held non-invasive blood pressure measurement device
US6340349B1 (en) 1993-11-09 2002-01-22 Medwave, Inc. Hand-held non-invasive blood pressure measurement device
US20060116588A1 (en) * 1993-11-09 2006-06-01 Archibald G K Method and apparatus for calculating blood pressure of an artery
US6413224B1 (en) * 1994-02-25 2002-07-02 Colin Corporation Blood pressure measuring apparatus
US6852083B2 (en) 1994-04-15 2005-02-08 Masimo Corporation System and method of determining whether to recalibrate a blood pressure monitor
US6371921B1 (en) 1994-04-15 2002-04-16 Masimo Corporation System and method of determining whether to recalibrate a blood pressure monitor
WO1996011628A1 (fr) * 1994-10-12 1996-04-25 Tovarischestvo S Ogranichennoi Otvetstvennostju 'russky Tsentr Perspektivnykh Tekhnology' (Russintsentr' Procede oscillometrique de determination des parametres haemodynamique de base dans la circulation arterielle d'un patient et systeme de mesure de mise en oeuvre dudit procede
US5743857A (en) * 1995-01-17 1998-04-28 Colin Corporation Blood pressure monitor apparatus
US5640964A (en) * 1995-02-16 1997-06-24 Medwave, Inc. Wrist mounted blood pressure sensor
US5738104A (en) * 1995-11-08 1998-04-14 Salutron, Inc. EKG based heart rate monitor
US6939305B2 (en) 1996-06-26 2005-09-06 Masimo Corporation Rapid non-invasive blood pressure measuring device
US7618375B2 (en) 1996-06-26 2009-11-17 Masimo Corporation Rapid non-invasive blood pressure measuring device
US7951086B2 (en) 1996-06-26 2011-05-31 Masimo Corporation Rapid non-invasive blood pressure measuring device
US6632181B2 (en) 1996-06-26 2003-10-14 Masimo Corporation Rapid non-invasive blood pressure measuring device
US5762610A (en) * 1996-07-03 1998-06-09 Colin Corporation Pressure pulse wave detecting apparatus
US6827688B2 (en) * 1996-10-24 2004-12-07 Colin Medical Technology Corporation Blood pressure monitor
US20030092999A1 (en) * 1996-10-24 2003-05-15 Colin Corporation Blood pressure monitor
ES2123439A1 (es) * 1996-10-30 1999-01-01 Univ Catalunya Politecnica Instrumento para medir la presion sanguinea arterial de forma no invasiva.
EP1074216A1 (de) * 1999-02-22 2001-02-07 Seiko Epson Corporation Blutdruckmessungsvorrichtung und vorrichtung zum nachweis von pulswellen
EP1074216A4 (de) * 1999-02-22 2004-09-08 Seiko Epson Corp Blutdruckmessungsvorrichtung und vorrichtung zum nachweis von pulswellen
EP1050267A1 (de) * 1999-05-06 2000-11-08 Colin Corporation Blutdruckmessgerät der oberen und unteren Glieder
US6355000B1 (en) 1999-05-06 2002-03-12 Colin Corporation Superior-and-inferior-limb blood-pressure index measuring apparatus
US6565515B2 (en) 1999-05-06 2003-05-20 Colin Corporation Pulse-wave-propagation-velocity-relating-information obtaining apparatus and blood-pressure-index measuring apparatus
EP1053714A2 (de) * 1999-05-17 2000-11-22 Colin Corporation Blutdruckmessgerät der oberen und unteren Glieder
US6379309B1 (en) 1999-05-17 2002-04-30 Colin Corporation Superior-and-inferior-limb blood-pressure index measuring apparatus and inferior-limb blood-pressure measuring apparatus
US6517493B2 (en) 1999-05-17 2003-02-11 Colin Corporation Superior-and-inferior-limb blood-pressure index measuring apparatus and inferior-limb blood-pressure measuring apparatus
EP1053714A3 (de) * 1999-05-17 2001-02-07 Colin Corporation Blutdruckmessgerät der oberen und unteren Glieder
CN1292705C (zh) * 2002-01-09 2007-01-03 欧姆龙健康医疗事业株式会社 动脉硬化评估仪器
EP1327415A1 (de) * 2002-01-09 2003-07-16 Colin Corporation Gerät zur Beurteilung von Arteriosklerose
US20030130578A1 (en) * 2002-01-09 2003-07-10 Colin Corporation Arteriosclerosis evaluating apparatus
US6955649B2 (en) 2002-01-09 2005-10-18 Colin Medical Technology Corporation Arteriosclerosis evaluating apparatus
US20030158489A1 (en) * 2002-02-18 2003-08-21 Colin Corporation Pressure-pulse-wave detecting apparatus
US6802814B2 (en) 2002-02-18 2004-10-12 Colin Medical Technology Corporation Pressure-pulse-wave detecting apparatus
EP1336374A1 (de) * 2002-02-18 2003-08-20 Colin Corporation Druckpulswellenmessgerät
EP1491136A4 (de) * 2002-03-28 2009-07-22 Omron Healthcare Co Ltd Elektronischer hämomanometer und blutdruckmessverfahren mit einem elektronischen hämomanometer
EP1491136A1 (de) * 2002-03-28 2004-12-29 Omron Corporation Elektronischer hämomanometer und blutdruckmessverfahren mit einem elektronischen hämomanometer
EP1374761A2 (de) * 2002-06-20 2004-01-02 Colin Corporation Vorrichtung zur Blutdruckbestimmung
US6869403B2 (en) * 2002-06-20 2005-03-22 Colin Medical Technology Corporation Blood-pressure determining apparatus
US20030236465A1 (en) * 2002-06-20 2003-12-25 Colin Corporation Blood-pressure determining apparatus
CN1306906C (zh) * 2002-06-20 2007-03-28 欧姆龙健康医疗事业株式会社 血压确定装置
EP1374761A3 (de) * 2002-06-20 2004-04-21 Colin Corporation Vorrichtung zur Blutdruckbestimmung
US20110237961A1 (en) * 2002-08-01 2011-09-29 Voss Gregory I Methods and apparatus for control of non-invasive parameter measurements
US8961426B2 (en) * 2002-08-01 2015-02-24 Tensys Medical, Inc. Method and apparatus for control of non-invasive parameter measurements
US20060094965A1 (en) * 2002-08-01 2006-05-04 Voss Gregory I Apparatus for control of non-invasive parameter measurements
US7976471B2 (en) 2002-08-01 2011-07-12 Tensys Medical, Inc. Method and apparatus for control of non-invasive parameter measurements
US20110263991A1 (en) * 2002-08-01 2011-10-27 Martin Gregory J Method and apparatus for control of non-invasive parameter measurements
US7955267B2 (en) 2002-08-01 2011-06-07 Voss Gregory I Apparatus for control of non-invasive parameter measurements
US8945016B2 (en) 2002-08-01 2015-02-03 Tensys Medical, Inc. Methods and apparatus for control of non-invasive parameter measurements
US7291112B2 (en) 2002-08-01 2007-11-06 Tensys Medical, Inc. Method and apparatus for control of non-invasive parameter measurements
US20040059234A1 (en) * 2002-08-01 2004-03-25 Martin Gregory J. Method and apparatus for control of non-invasive parameter measurements
US20080064968A1 (en) * 2002-08-01 2008-03-13 Martin Gregory J Method and apparatus for control of non-invasive parameter measurements
US6974419B1 (en) 2002-08-01 2005-12-13 Tensys Medical, Inc. Method and apparatus for control of non-invasive parameter measurements
US20040225224A1 (en) * 2003-05-05 2004-11-11 Tseng Daniel C.M. Integrated inflating and quick releasing device for electronic sphygmomanometer
US7341561B2 (en) * 2003-05-30 2008-03-11 Casio Computer Co., Ltd. Wrist-worn high-accuracy pulsation measuring apparatus
US20040243009A1 (en) * 2003-05-30 2004-12-02 Casio Computer Co., Ltd. Wrist-worn high-accuracy pulsation measuring apparatus
US20050283082A1 (en) * 2004-06-21 2005-12-22 Geddes Leslie A Optical noninvasive vital sign monitor
US7164938B2 (en) 2004-06-21 2007-01-16 Purdue Research Foundation Optical noninvasive vital sign monitor
US7014611B1 (en) * 2004-06-24 2006-03-21 Purdue Research Foundation Oscillometric noninvasive blood pressure monitor
US9247886B2 (en) 2004-10-07 2016-02-02 Tensys Medical, Inc. Compact apparatus and methods for non-invasively measuring hemodynamic parameters
US7946994B2 (en) 2004-10-07 2011-05-24 Tensys Medical, Inc. Compact apparatus and methods for non-invasively measuring hemodynamic parameters
US20060258944A1 (en) * 2005-04-22 2006-11-16 Fukuda Denshi Co. Ltd. Device and method for outputting bioinformation and bioinformation report
EP1715429A1 (de) * 2005-04-22 2006-10-25 Fukuda Denshi Co., Ltd. Gerät und Methode um Bioinformation, speziell Blutdruck und Pulswelle, anzuzeigen
US20070287925A1 (en) * 2006-05-13 2007-12-13 Katayama Andrew S Continuous positioning apparatus and methods
US8506497B2 (en) 2006-05-13 2013-08-13 Tensys Medical, Inc. Continuous positioning apparatus and methods
US9107588B2 (en) 2006-05-13 2015-08-18 Tensys Medical, Inc. Continuous positioning apparatus and methods
US10285598B2 (en) 2006-05-13 2019-05-14 United States Gtm Medical Devices Continuous positioning apparatus and methods
US7390302B2 (en) * 2006-08-16 2008-06-24 The General Electric Company Method and system of determining NIBP target inflation pressure using an SpO2 plethysmograph signal
US20080045846A1 (en) * 2006-08-16 2008-02-21 Friedman Bruce A Method and system of determining nibp target inflation pressure using an sp02 plethysmograph signal
US10952675B2 (en) 2007-10-12 2021-03-23 Shangyi Medical Technology (Hangzhou) Co., Ltd Apparatus and methods for non-invasively measuring a patient's arterial blood pressure
US8211030B2 (en) 2009-03-26 2012-07-03 The General Electric Company NIBP target inflation pressure automation using derived SPO2 signals
US20100249616A1 (en) * 2009-03-26 2010-09-30 The General Electric Company Nibp target inflation pressure automation using derived spo2 signals
US20170181648A1 (en) * 2014-02-13 2017-06-29 Nec Corporation Blood pressure estimation device, blood pressure estimation method, blood pressure measurement device, and recording medium
US10194811B2 (en) * 2014-02-13 2019-02-05 Nec Corporation Blood pressure measurement device, blood pressure measurement method, and non-transitory recording medium
US11083385B2 (en) * 2015-01-26 2021-08-10 University Of Ulsan Foundation For Industry Cooperation Apparatus for measuring blood circulation disorders, and method therefor

Also Published As

Publication number Publication date
FR2678157A1 (fr) 1992-12-31
GB2257529A (en) 1993-01-13
FR2678157B1 (fr) 1998-05-07
JPH053858A (ja) 1993-01-14
DE4220532A1 (de) 1993-01-14
GB9213435D0 (en) 1992-08-05
GB2257529B (en) 1995-06-07

Similar Documents

Publication Publication Date Title
US5261414A (en) Blood pressure monitor system
US5279303A (en) Blood pressure monitor system
US5033471A (en) Method and apparatus measuring blood pressure
US6068601A (en) Blood pressure measuring apparatus
US5791348A (en) Automatic blood pressure measuring system
US6645154B2 (en) Blood-pressure-waveform monitoring apparatus
US5119824A (en) Heartbeat synchronous wave detecting apparatus
US5921936A (en) System and method for evaluating the circulatory system of a living subject
US5830149A (en) Physical information monitor system having means for indicating amount of deviation of monitored information from normal information
EP0510720A2 (de) Vefahren und Gerät zur Überwachung des Blutdruckes
US6645156B2 (en) Continuous blood-pressure monitoring apparatus
EP0297146B1 (de) Blutdruckregelungssystem
US6610017B2 (en) Continuous blood-pressure monitoring apparatus
US6602198B2 (en) Automatic blood-pressure measuring apparatus
US6346083B1 (en) Blood-pressure measuring device
EP0838194B1 (de) Physikalisches Informations-Überwachungssystem mit Anzeigevorrichtung für den Abweichungsbetrag einer überwachten Information vom Sollwert
US6802814B2 (en) Pressure-pulse-wave detecting apparatus
EP0830840B1 (de) Anordnung zur Überwachung von physikalischen Grössen mit Mitteln zur Bestimmung eines Referenzbereichs um Anomalien in gespeicherten Informationen festzustellen
EP0401382B1 (de) Vorrichtung und verfahren zur detektion von pulswellen
EP0775465B1 (de) Automatisches sphygmomanometer
US5590661A (en) Blood pressure measuring apparatus
US6394959B1 (en) Continuous blood-pressure monitor apparatus
JP3795663B2 (ja) 連続血圧監視装置
JPH1119054A (ja) 押圧補正型連続血圧監視装置
JP3975604B2 (ja) 動脈硬化度測定装置

Legal Events

Date Code Title Description
AS Assignment

Owner name: COLIN ELECTRONICS CO., LTD., JAPAN

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNORS:AUNG, YE;TAKAYA, MASAMI;NISHIBAYASHI, HIDEO;REEL/FRAME:006199/0401

Effective date: 19920615

FPAY Fee payment

Year of fee payment: 4

FEPP Fee payment procedure

Free format text: PAYOR NUMBER ASSIGNED (ORIGINAL EVENT CODE: ASPN); ENTITY STATUS OF PATENT OWNER: SMALL ENTITY

FPAY Fee payment

Year of fee payment: 8

AS Assignment

Owner name: COLIN MEDICAL TECHNOLOGY CORPORATION, JAPAN

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:COLIN ELECTRONICS CO., LTD.;REEL/FRAME:014428/0957

Effective date: 20040205

REMI Maintenance fee reminder mailed
LAPS Lapse for failure to pay maintenance fees
STCH Information on status: patent discontinuation

Free format text: PATENT EXPIRED DUE TO NONPAYMENT OF MAINTENANCE FEES UNDER 37 CFR 1.362

FP Lapsed due to failure to pay maintenance fee

Effective date: 20051116