US4617924A - Method and apparatus for artificial respiration and the measurement of breathing gas values - Google Patents
Method and apparatus for artificial respiration and the measurement of breathing gas values Download PDFInfo
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- US4617924A US4617924A US06/693,016 US69301685A US4617924A US 4617924 A US4617924 A US 4617924A US 69301685 A US69301685 A US 69301685A US 4617924 A US4617924 A US 4617924A
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- breathing gas
- breathing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0096—High frequency jet ventilation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/1005—Preparation of respiratory gases or vapours with O2 features or with parameter measurement
- A61M16/1015—Preparation of respiratory gases or vapours with O2 features or with parameter measurement using a gas flush valve, e.g. oxygen flush valve
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0027—Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/40—Respiratory characteristics
- A61M2230/43—Composition of exhalation
- A61M2230/432—Composition of exhalation partial CO2 pressure (P-CO2)
Definitions
- This invention relates in general to respirators and in particular to a new and useful method and apparatus for controlling the flow of breathing gas to a patient and for creating a measuring interval during the respiration in which various breathing gas characteristics are determined.
- German Pat. No. 20 47 659 discloses a ventilation system wherein the breathing gas source in HFJV operation produces high-pressure gas-pulses having a pulse recurrence frequency in excess of 600 per minute, and alternately pulse trains and pauses therebetween are provided. The pauses are intended as intervals for examining gas samples. The gas samples are analyzed in a respective device and depending on the result, the control of the ventilation can be adjusted to obtain the best respiration pattern.
- the CO 2 concentration i.e. CO 2 content in the exhaled air, which is measured at the end of an expiration phase to determine the partial pressure of CO 2 in the blood, is a generally acknowledged important control variable in conventional ventilation (Intermittent Positive Pressure Ventilation or IPPV) without a pulse control. While in a conventional ventilation, the determination of the CO 2 content of the exhaled air is not particularly difficult, during high-frequency ventilation, the CO 2 determination is not so easy.
- the exhaled gas is strongly diluted by the continuous flow of flush gas, and because of the minimum volumina per stroke during the high-frequency ventilation, which are on the order of magnitude of the dead space of the breathing gas supply device the CO 2 concentration in the exhaled gas does not correspond to that of the alveolar region.
- a prior art qualitative measurement utilizes thorax bloating for inferring therefrom the pressure built up in the lungs.
- the thorax impedance can be determined in a known manner through electrodes applied to the chest, or strain bands placed on the chest, extending and thus providing resistance values to be measured.
- Such measurements furnish only coarse information on the lung-internal PEEP and the fixing of measuring elements or bands may be difficult, particularly with a traumatic chest.
- the invention is directed to a system of the above mentioned which permits the determination during a high-frequency ventilation of the expiratory CO 2 concentration and thus the CO 2 partial pressure in the blood, and in addition to quantitatively determine from the exhaled air the lung-internal PEEP i.e. the basic pressure building up in the lungs during HFJV.
- the controller is connected to a flush gas valve provided upstream of the breathing gas supply device and is so designed that after a sequence of breathing gas pulses, a measuring interval is intercalated during at least part of which the breathing gas valve and the flush gas valve are closed, and that at least one system for measuring breathing gas values is provided in the outlet line which is put in operation during the measuring interval to determine the measured values.
- the breathing gas valve and the flush gas valve are not necessarily simultaneously closed during the entire measuring interval, since a control displaced in phase with these valves may be advisable in certain applications, even though in any case with an overlapping in the measuring interval.
- Developments of the invention include special design of the measuring system as a CO 2 analyzer and flowmeter, and arrangements with a multiplier in addition, with the possibility of determining the total inhaled CO 2 amount for a longer period of time, or the CO 2 production per unit time, through an integrator controlled by the controller.
- the high-frequency ventilation is interrupted and, prior to starting the measuring interval, transformed into a conventional breathing pattern.
- This may advantageously be obtained by correspondingly extending the pulse duration and reducing the pulse spacing, in a way so as to produce long strokes similar to the conventional positive excess pressure duration (IPPV).
- IPPV positive excess pressure duration
- the control device switches the breathing gas valve and the flush gas valve into closed positions, so that only expiration gas now flows in the outlet line, having a CO 2 concentration which corresponds to the alveolar CO 2 concentration.
- the measuring system connected in the outlet line in the present example includes a CO 2 analyzer, which is then instructed to perform the measuring operation.
- the high frequency ventilation is interrupted by closing the breathing gas valve and the flush gas valve for a period of time corresponding to several high-frequency pulse cycles, and at the same time, after the last high-frequency pulse, the expiration gas flow is measured with a flowmeter and integrated by means of an integrator connected to the flowmeter, until the flow drops to zero.
- the value of the integral up to the point at which, with a continuous high-frequency pulse train, the next high-frequency pulse would have started, corresponds to the tidal volume in the high-frequency ventilation; the total integral minus the tidal volume corresponds to the basic bloating. With the known compliance of the lungs this value can be used for computing the internal PEEP.
- the compliance of the lungs may vary during long term ventilation, it is advisable to determine the compliance value shortly before or after measuring the expiration volume as described above.
- the compliance may be measured to determine the end expiratory CO 2 concentration.
- a conventional breathing stroke is produced with the jet nozzle, while selecting a long inspiration time to obtain a definite pressure level (plateau).
- the pressure present in the upper portion of the respiratory tract is measured by means of a pressure pickup provided in the breathing gas supply device, at a location remote from the orifice of the jet nozzle.
- the breathing gas flow to the jet nozzle is interrupted through the breathing gas valve and the flush gas flow is interrupted through the flush gas valve, so that with a corresponding triggering of the integrator, the expiration volume can be determined by means of the flowmeter in the outlet line.
- the actual compliance of the lungs and thus, as mentioned above, the lung-internal PEEP, can be computed.
- a breathing gas supply device is supplied with breathing gas through a control valve and it has an opposite end which is connected through the device to the patient.
- a flushing gas is connected into the device to provide means for flushing the device of the exhaled air through an outlet.
- the flushing gas is also controlled by a valve and the controller is connected to the breathing gas valve and the flushing gas valve so as to control their operation and provide a measuring interval for a predetermined period in which the exhaled gas is passed through measuring means such as a CO 2 analyzer, pressure sensor or the like during which time the breathing gas and flushing gas supplies are discontinued.
- a further object of the invention is to provide a ventilation system which is simple in design, rugged in construction and economical to manufacture.
- FIG. 1 is a schematic diagram of a ventilation system with controlled breathing gas and flush gas valves, for determining the CO 2 concentration, and construction in accordance with the invention.
- FIG. 2 illustrates a similar system for determining the lung-internal PEEP.
- FIG. 1 comprises a ventilating system for breathing apparatus which includes a breathing gas source 20 which supplies breathing gas through a breathing gas supply line to a breathing gas supply device generally designated 2.
- the gas supply line 1 has a breathing gas control valve 5 therein which is regulated through a control line 7 from a controller 22.
- a flushing gas supply 24 is connected through a flushing gas supply line 4 to the breathing gas supply device 2 and the flushing gas flow is regulated by a valve 6 which is also controlled by the controller 22 through a control line 8.
- Flushing gas supply 24 may supply the same gas as breathing gas source 20.
- the control means or controller 22 provides a measuring interval which provides for the interruption of a supply of breathing gas regulating the valve 5 and flushing gas by regulating the valve 6 for a measuring interval or period in which the exhaled gas is directed through measuring means including the CO 2 analyzer 26.
- the ventilation source which may be combined with the breathing gas source, is connected through a flush gas line 4 to the breathing gas supply device 2.
- the breathing gas valve 5 controllable at high frequency is provided.
- the controllable flush gas valve 6 is provided in the flush gas line 4.
- Breathing gas valve 5 and flush gas valve 6 are controlled through the high-frequency controller 22 which is connected to these valves through control lines 7,8.
- Measuring means comprising a CO 2 analyzer 26 and a flowmeter are provided in an outlet line 9 leading outwardly from gas supply device 2.
- Signal lines 10 and 11 connect the high-frequency controller to an integrator and to the CO 2 analyzer.
- Output lines 12,13 from the CO 2 analyzer and the flowmeter are applied to a multiplier whose output is connected through a line 14 to the integrator.
- the ventilating system with the two controllable valves 5,6 serves the purpose of determining the alveolar CO 2 concentration.
- the substantial parts of the system namely the breathing gas source, the flush gas source, the high-frequency controller, the controllable valves for the breathing gas and the flush gas, and the breathing gas supply device, are maintained without change.
- a line 15 is connected leading to a pressure sensor whose output is applied to an arithmetic unit.
- the output of the flowmeter is connected through a line 17 to the integrator which also is connected, through a signal line 18, to the arithmetic unit.
- This unit is in addition connected, through another signal line 19, to the high-frequency controller.
- Another signal line 20 connects the high-frequency controller to the integrator.
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- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Respiratory Apparatuses And Protective Means (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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Abstract
A ventilating system includes a high frequency controlled breathing gas source in HFJV operation, wherein the exhaled gas is removed through an outlet line through which a flush gas is conducted, is improved to permit a determination, under high frequency ventilation, of both the final expiratory CO2 concentration and the basic pressure building up in the lungs (the lung-internal PEEP). To this end, the control device is in addition connected to a flush gas valve provided upstream of the breathing gas supply device, and designed to intercalate a measuring interval after a sequence of breathing gas pulses, during which interval the breathing gas valve and the flush gas valve are closed. A system of measuring the breathing gas valves is provided in the outlet line and it is actuated during the measuring interval to perform the measuring operation.
Description
This invention relates in general to respirators and in particular to a new and useful method and apparatus for controlling the flow of breathing gas to a patient and for creating a measuring interval during the respiration in which various breathing gas characteristics are determined.
Substantial problems arise in the monitoring of an artificial respiration with a quick and accurate determination of breathing gas values and ventilation parameters, especially if a high frequency pulse method where a jet nozzle (High Frequency Jet Ventilation or HFJV) is used.
German Pat. No. 20 47 659 discloses a ventilation system wherein the breathing gas source in HFJV operation produces high-pressure gas-pulses having a pulse recurrence frequency in excess of 600 per minute, and alternately pulse trains and pauses therebetween are provided. The pauses are intended as intervals for examining gas samples. The gas samples are analyzed in a respective device and depending on the result, the control of the ventilation can be adjusted to obtain the best respiration pattern.
The CO2 concentration, i.e. CO2 content in the exhaled air, which is measured at the end of an expiration phase to determine the partial pressure of CO2 in the blood, is a generally acknowledged important control variable in conventional ventilation (Intermittent Positive Pressure Ventilation or IPPV) without a pulse control. While in a conventional ventilation, the determination of the CO2 content of the exhaled air is not particularly difficult, during high-frequency ventilation, the CO2 determination is not so easy. The exhaled gas is strongly diluted by the continuous flow of flush gas, and because of the minimum volumina per stroke during the high-frequency ventilation, which are on the order of magnitude of the dead space of the breathing gas supply device the CO2 concentration in the exhaled gas does not correspond to that of the alveolar region.
Another problem in high-frequency ventilation of a patient is the determination of the constant basic pressure established in the lungs, the so called "lung-internal PEEP". At high ventilation frequencies, about in the range of 600 per minute, such as usual in this kind of ventilation, the so called "air trapping" builds up a pressure in the lungs, which does not decay at the end of the short expiration phases. With methods hitherto known, this internal PEEP (Positive End Expiratory Pressure) cannot be measured with satisfactory accuracy.
A prior art qualitative measurement utilizes thorax bloating for inferring therefrom the pressure built up in the lungs. To this end, the thorax impedance can be determined in a known manner through electrodes applied to the chest, or strain bands placed on the chest, extending and thus providing resistance values to be measured. Such measurements furnish only coarse information on the lung-internal PEEP and the fixing of measuring elements or bands may be difficult, particularly with a traumatic chest.
The invention is directed to a system of the above mentioned which permits the determination during a high-frequency ventilation of the expiratory CO2 concentration and thus the CO2 partial pressure in the blood, and in addition to quantitatively determine from the exhaled air the lung-internal PEEP i.e. the basic pressure building up in the lungs during HFJV.
This is obtained by providing that the controller is connected to a flush gas valve provided upstream of the breathing gas supply device and is so designed that after a sequence of breathing gas pulses, a measuring interval is intercalated during at least part of which the breathing gas valve and the flush gas valve are closed, and that at least one system for measuring breathing gas values is provided in the outlet line which is put in operation during the measuring interval to determine the measured values. The breathing gas valve and the flush gas valve are not necessarily simultaneously closed during the entire measuring interval, since a control displaced in phase with these valves may be advisable in certain applications, even though in any case with an overlapping in the measuring interval.
Developments of the invention include special design of the measuring system as a CO2 analyzer and flowmeter, and arrangements with a multiplier in addition, with the possibility of determining the total inhaled CO2 amount for a longer period of time, or the CO2 production per unit time, through an integrator controlled by the controller.
To determine the CO2 concentration in such a ventilating system, first, by correspndingly controlling the breathing gas valve, the high-frequency ventilation is interrupted and, prior to starting the measuring interval, transformed into a conventional breathing pattern. This may advantageously be obtained by correspondingly extending the pulse duration and reducing the pulse spacing, in a way so as to produce long strokes similar to the conventional positive excess pressure duration (IPPV). This is to make sure that the CO2 concentration in the expiration gas examined during the measuring interval corresponds to the alveolar CO2 concentration. After the last bloating caused by the breathing gas supply, the control device switches the breathing gas valve and the flush gas valve into closed positions, so that only expiration gas now flows in the outlet line, having a CO2 concentration which corresponds to the alveolar CO2 concentration. The measuring system connected in the outlet line, in the present example includes a CO2 analyzer, which is then instructed to perform the measuring operation.
To determine the lung-internal PEEP, the high frequency ventilation is interrupted by closing the breathing gas valve and the flush gas valve for a period of time corresponding to several high-frequency pulse cycles, and at the same time, after the last high-frequency pulse, the expiration gas flow is measured with a flowmeter and integrated by means of an integrator connected to the flowmeter, until the flow drops to zero.
The value of the integral up to the point at which, with a continuous high-frequency pulse train, the next high-frequency pulse would have started, corresponds to the tidal volume in the high-frequency ventilation; the total integral minus the tidal volume corresponds to the basic bloating. With the known compliance of the lungs this value can be used for computing the internal PEEP.
Since the compliance of the lungs may vary during long term ventilation, it is advisable to determine the compliance value shortly before or after measuring the expiration volume as described above. In the concerned ventilating system and analogously to the above mentioned measuring process, the compliance may be measured to determine the end expiratory CO2 concentration.
To this end, a conventional breathing stroke is produced with the jet nozzle, while selecting a long inspiration time to obtain a definite pressure level (plateau). Upon reaching this predetermined pressure level, the pressure present in the upper portion of the respiratory tract is measured by means of a pressure pickup provided in the breathing gas supply device, at a location remote from the orifice of the jet nozzle. During the following expiration phase, and in the same way as in the determination of the expiratory CO2 concentration, the breathing gas flow to the jet nozzle is interrupted through the breathing gas valve and the flush gas flow is interrupted through the flush gas valve, so that with a corresponding triggering of the integrator, the expiration volume can be determined by means of the flowmeter in the outlet line.
From the measured plateau pressure and the expiration value, the actual compliance of the lungs and thus, as mentioned above, the lung-internal PEEP, can be computed.
What is substantial in the inventive arrangement is the provision of a control flush gas valve, in addition to the high-frequency controlled breathing gas valve producing the breathing gas pulses. This makes it possible to obtain reliable values of the alveolar CO2 concentration, the lung-internal PEEP, and the actual compliance in a manner that is unaffected by the flush gas flow.
In accordance with the invention a breathing gas supply device is supplied with breathing gas through a control valve and it has an opposite end which is connected through the device to the patient. In addition, a flushing gas is connected into the device to provide means for flushing the device of the exhaled air through an outlet. The flushing gas is also controlled by a valve and the controller is connected to the breathing gas valve and the flushing gas valve so as to control their operation and provide a measuring interval for a predetermined period in which the exhaled gas is passed through measuring means such as a CO2 analyzer, pressure sensor or the like during which time the breathing gas and flushing gas supplies are discontinued.
A further object of the invention is to provide a ventilation system which is simple in design, rugged in construction and economical to manufacture.
The various features of novelty which characterize the invention are pointed out with particularity in the claims annexed to and forming a part of this disclosure. For a better understanding of the invention, its operating advantages and specific objects attained by its uses, reference is made to the accompanying drawings and descriptive matter in which preferred embodiments of the invention are illustrated.
In the drawings:
FIG. 1 is a schematic diagram of a ventilation system with controlled breathing gas and flush gas valves, for determining the CO2 concentration, and construction in accordance with the invention; and
FIG. 2 illustrates a similar system for determining the lung-internal PEEP.
Referring to the drawings in particular the invention embodied therein in FIG. 1 comprises a ventilating system for breathing apparatus which includes a breathing gas source 20 which supplies breathing gas through a breathing gas supply line to a breathing gas supply device generally designated 2. The gas supply line 1 has a breathing gas control valve 5 therein which is regulated through a control line 7 from a controller 22. A flushing gas supply 24 is connected through a flushing gas supply line 4 to the breathing gas supply device 2 and the flushing gas flow is regulated by a valve 6 which is also controlled by the controller 22 through a control line 8. Flushing gas supply 24 may supply the same gas as breathing gas source 20. The control means or controller 22 provides a measuring interval which provides for the interruption of a supply of breathing gas regulating the valve 5 and flushing gas by regulating the valve 6 for a measuring interval or period in which the exhaled gas is directed through measuring means including the CO2 analyzer 26.
The ventilation source, which may be combined with the breathing gas source, is connected through a flush gas line 4 to the breathing gas supply device 2. In the supply line 1, the breathing gas valve 5 controllable at high frequency is provided. In the flush gas line 4, the controllable flush gas valve 6 is provided.
Breathing gas valve 5 and flush gas valve 6 are controlled through the high-frequency controller 22 which is connected to these valves through control lines 7,8.
Measuring means comprising a CO2 analyzer 26 and a flowmeter are provided in an outlet line 9 leading outwardly from gas supply device 2.
In this circuit arrangement, the ventilating system with the two controllable valves 5,6 serves the purpose of determining the alveolar CO2 concentration.
In the arrangement of FIG. 2, the substantial parts of the system, namely the breathing gas source, the flush gas source, the high-frequency controller, the controllable valves for the breathing gas and the flush gas, and the breathing gas supply device, are maintained without change.
In the breathing gas supply device 2, at a location remote from the orifice of the jet nozzle 3, a line 15 is connected leading to a pressure sensor whose output is applied to an arithmetic unit. The output of the flowmeter is connected through a line 17 to the integrator which also is connected, through a signal line 18, to the arithmetic unit. This unit is in addition connected, through another signal line 19, to the high-frequency controller. Another signal line 20 connects the high-frequency controller to the integrator.
While specific embodiments of the invention have been shown and described in detail to illustrate the application of the principles of the invention, it will be understood that the invention may be embodied otherwise without departing from such principles.
Claims (10)
1. A ventilating system comprising a breathing gas source for supplying a flow of breathing gas, a breathing gas supply line having one end connected to said breathing gas source and having an opposite end with a jet nozzle, a breathing gas supply device having one end connected to said opposite end of said breathing gas supply line for receiving the flow of breathing gas over said jet nozzle, a flushing gas line connected into said breathing gas supply device, an always open outlet line connected into said breathing gas supply device, said breathing gas supply device having an end for connection to a patient, a breathing gas valve in said breathing gas line for regulating the breathing gas flow to said breathing gas supply device, a flush gas valve in said flushing gas line for regulating the flow of flushing gas to said breathing gas supply device and to said outlet line, and control means connected to said breathing gas valve and said flushing gas valve for providing the flow of breathing gas through said breathing gas valve in high frequency pulses for a predetermined period and said flushing gas through said flushing gas valve for a predetermined period and providing a measuring interval in which said breathing gas valve and said flushing gas valve are closed, and measuring means connected to said outlet for measuring breathing gas values during the measuring interval.
2. A ventilating system according to claim 1, wherein said measuring means comprises a CO2 analyzer.
3. A ventilating system according to claim 2, including a multiplier connected to said CO2 analyzer and a flowmeter connected to said CO2 analyzer, an integrator connected to the output of said multiplier and a signal line connected between said control means and said multiplier.
4. A ventilating system according to claim 1, including a flowmeter in said outlet line.
5. A ventilating system according to claim 4, including an integrator connected to said flowmeter, a signal line connecting said integrator to said control means, a pressure sensor connected to said breathing gas supply device, an arithmetic unit connected to said pressure sensor, a signal line connected between said arithmetic unit and said integrator and a signal line connected between said control means and said integrator.
6. A ventilating system according to claim 5, wherein said pressure sensor is connected to said breathing gas supply device at a location remote from the connection of said breathing gas supply line and from said supply device, said breathing gas jet nozzle.
7. A ventilating system according to claim 1, wherein said control means has means which effects the measuring interval at predetermined periodic recurring times.
8. A ventilating system according to claim 1, wherein said control means has means which effects prior to the start of a measuring interval, the duration of a breathing gas pulse and the pulse duration to spacing ratio and provides means for modifying them to obtain a conventional breathing pattern.
9. A method of effecting the respiration of a patient comprising:
supplying breathing gas in high frequency pulses and over a jet nozzle to a breathing gas supply device;
supplying flushing gas to the breathing gas supply device;
connecting the breathing gas supply device to a patient for supplying the patient with the high frequency pulses of breathing gas and with the flushing gas;
interrupting the supply of high frequency breathing pulses as well as the supply of flushing gas during a measuring interval, the patient exhaling through the breathing gas supply device during the measuring interval into an outlet connected to the breathing gas supply device that is always open; and
measuring at least one parameter of gas in the outlet during the measuring interval.
10. A method according to claim 9, in which a measuring interval is provided after discontinuing the supply of breathing gas and flushing gas and wherein the exhaled gas is directed through a CO2 analyzer through a flowmeter and the indications of the flowmeter and the CO2 analyzer are given to an integrator wherein control means are connected to the breathing gas supply and the flushing gas supply for discontinuing the supplies during a measuring interval during the respiration.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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DE19843401841 DE3401841A1 (en) | 1984-01-20 | 1984-01-20 | VENTILATION SYSTEM AND OPERATING METHOD THEREFOR |
DE3401841 | 1984-01-20 |
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US4617924A true US4617924A (en) | 1986-10-21 |
Family
ID=6225417
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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US06/693,016 Expired - Fee Related US4617924A (en) | 1984-01-20 | 1985-01-18 | Method and apparatus for artificial respiration and the measurement of breathing gas values |
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US (1) | US4617924A (en) |
EP (1) | EP0149722B1 (en) |
JP (2) | JPS60160968A (en) |
AT (1) | ATE38780T1 (en) |
BR (1) | BR8500182A (en) |
DE (2) | DE3401841A1 (en) |
Cited By (21)
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WO1987006040A1 (en) * | 1986-03-31 | 1987-10-08 | Puritan-Bennett Corporation | Computer gated positive expiratory pressure system |
US4747403A (en) * | 1986-01-27 | 1988-05-31 | Advanced Pulmonary Technologies, Inc. | Multi-frequency jet ventilation technique and apparatus |
US4838259A (en) * | 1986-01-27 | 1989-06-13 | Advanced Pulmonary Technologies, Inc. | Multi-frequency jet ventilation technique and apparatus |
US4986268A (en) * | 1988-04-06 | 1991-01-22 | Tehrani Fleur T | Method and apparatus for controlling an artificial respirator |
US5040529A (en) * | 1984-11-20 | 1991-08-20 | B.O.C.S.A. | Process for artificial ventilation for assisting the volumetric breathing of a patient |
US5092326A (en) * | 1987-11-19 | 1992-03-03 | Winn Bryan D | Apparatus and method for a ventilator system |
US5150291A (en) * | 1986-03-31 | 1992-09-22 | Puritan-Bennett Corporation | Respiratory ventilation apparatus |
US5438980A (en) * | 1993-01-12 | 1995-08-08 | Puritan-Bennett Corporation | Inhalation/exhalation respiratory phase detection circuit |
US5522381A (en) * | 1993-07-22 | 1996-06-04 | Siemens-Elema Ab | Device for supplying breathing gas to the lungs of a respiratory subject |
US6152133A (en) * | 1998-07-17 | 2000-11-28 | Siemens Elema Ab | Anaesthetic delivery system |
US6196222B1 (en) | 1998-03-10 | 2001-03-06 | Instrumentarium Corporation | Tracheal gas insufflation delivery system for respiration equipment |
US6298848B1 (en) * | 1998-10-27 | 2001-10-09 | Siemens-Elema Ab | Device for flushing a deadspace in mechanical ventilation |
US6484721B1 (en) * | 2001-06-27 | 2002-11-26 | Chad Therapeutics, Inc. | Pneumatic oxygen conserving device |
US6622725B1 (en) * | 2000-03-31 | 2003-09-23 | Joseph A. Fisher | Rebreathing circuit to set and stabilize end tidal and arterial PCO2 despite varying levels of minute ventilation |
EP1449559A1 (en) * | 2003-02-18 | 2004-08-25 | INO Therapeutics GmbH | Metered delivery of therapeutic gas |
US7448594B2 (en) | 2004-10-21 | 2008-11-11 | Ameriflo, Inc. | Fluid regulator |
US20090126731A1 (en) * | 2007-11-19 | 2009-05-21 | Allegiance Corporation | Patient interface assembly for respiratory therapy |
US7617826B1 (en) | 2004-02-26 | 2009-11-17 | Ameriflo, Inc. | Conserver |
US8146592B2 (en) | 2004-02-26 | 2012-04-03 | Ameriflo, Inc. | Method and apparatus for regulating fluid flow or conserving fluid flow |
US20200215278A1 (en) * | 2012-06-26 | 2020-07-09 | Resmed Sensor Technologies Limited | Methods and apparatus for monitoring and treating respiratory insufficiency |
US11850077B2 (en) | 2012-05-30 | 2023-12-26 | Resmed Sensor Technologies Limited | Method and apparatus for monitoring cardio-pulmonary health |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4120313C2 (en) * | 1991-06-20 | 1995-03-09 | Schaller Peter Dr Sc Techn | Circuit arrangement for controlling the oscillation amplitude in high-frequency ventilation |
EP0823849B1 (en) * | 1995-05-02 | 1999-12-22 | Aloy, Alexander, Dr. | Device for administering a gas to be inhaled |
CN102283628B (en) * | 2011-07-08 | 2013-09-11 | 舒妮 | Electronic control high-efficiency jet ventilation laryngoscope |
Citations (6)
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DE2744327C2 (en) * | 1976-10-07 | 1982-04-15 | Drägerwerk AG, 2400 Lübeck | Ventilation system |
DE2947659C2 (en) * | 1979-11-27 | 1986-11-20 | Drägerwerk AG, 2400 Lübeck | Ventilator |
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1984
- 1984-01-20 DE DE19843401841 patent/DE3401841A1/en active Granted
- 1984-10-03 EP EP84111820A patent/EP0149722B1/en not_active Expired
- 1984-10-03 DE DE8484111820T patent/DE3475271D1/en not_active Expired
- 1984-10-03 AT AT84111820T patent/ATE38780T1/en active
-
1985
- 1985-01-16 BR BR8500182A patent/BR8500182A/en unknown
- 1985-01-18 US US06/693,016 patent/US4617924A/en not_active Expired - Fee Related
- 1985-01-18 JP JP60006030A patent/JPS60160968A/en active Granted
- 1985-01-18 JP JP60006031A patent/JPS60222066A/en active Pending
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US3799149A (en) * | 1972-12-26 | 1974-03-26 | Nasa | Metabolic analyzer |
US3894536A (en) * | 1973-01-29 | 1975-07-15 | Jungner Instrument Ab | Lung ventilator including volume meter for measuring total volume |
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US4444201A (en) * | 1980-08-27 | 1984-04-24 | Tokyo Shibaura Denki Kabushiki Kaisha | Respiration monitoring apparatus and method |
US4481944A (en) * | 1981-11-19 | 1984-11-13 | Bunnell Life Systems, Inc. | Apparatus and method for assisting respiration |
US4508117A (en) * | 1982-09-13 | 1985-04-02 | Soxil S.P.A. | Apparatus for artificial pulmonary ventilation during anaesthesia and resuscitation |
Cited By (32)
Publication number | Priority date | Publication date | Assignee | Title |
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US5040529A (en) * | 1984-11-20 | 1991-08-20 | B.O.C.S.A. | Process for artificial ventilation for assisting the volumetric breathing of a patient |
US4838259A (en) * | 1986-01-27 | 1989-06-13 | Advanced Pulmonary Technologies, Inc. | Multi-frequency jet ventilation technique and apparatus |
US4747403A (en) * | 1986-01-27 | 1988-05-31 | Advanced Pulmonary Technologies, Inc. | Multi-frequency jet ventilation technique and apparatus |
US5150291A (en) * | 1986-03-31 | 1992-09-22 | Puritan-Bennett Corporation | Respiratory ventilation apparatus |
GB2194892B (en) * | 1986-03-31 | 1990-05-09 | Puritan Bennett Corp | Computer gated positive expiratory pressure system |
AU598255B2 (en) * | 1986-03-31 | 1990-06-21 | Puritan-Bennett Corporation | Computer gated positive expiratory pressure system |
GB2194892A (en) * | 1986-03-31 | 1988-03-23 | Puritan Bennett Corp | Computer gated positive expiratory pressure system |
WO1987006040A1 (en) * | 1986-03-31 | 1987-10-08 | Puritan-Bennett Corporation | Computer gated positive expiratory pressure system |
US5092326A (en) * | 1987-11-19 | 1992-03-03 | Winn Bryan D | Apparatus and method for a ventilator system |
US4986268A (en) * | 1988-04-06 | 1991-01-22 | Tehrani Fleur T | Method and apparatus for controlling an artificial respirator |
US5438980A (en) * | 1993-01-12 | 1995-08-08 | Puritan-Bennett Corporation | Inhalation/exhalation respiratory phase detection circuit |
US5522381A (en) * | 1993-07-22 | 1996-06-04 | Siemens-Elema Ab | Device for supplying breathing gas to the lungs of a respiratory subject |
US6196222B1 (en) | 1998-03-10 | 2001-03-06 | Instrumentarium Corporation | Tracheal gas insufflation delivery system for respiration equipment |
US6152133A (en) * | 1998-07-17 | 2000-11-28 | Siemens Elema Ab | Anaesthetic delivery system |
US6298848B1 (en) * | 1998-10-27 | 2001-10-09 | Siemens-Elema Ab | Device for flushing a deadspace in mechanical ventilation |
US6622725B1 (en) * | 2000-03-31 | 2003-09-23 | Joseph A. Fisher | Rebreathing circuit to set and stabilize end tidal and arterial PCO2 despite varying levels of minute ventilation |
US6484721B1 (en) * | 2001-06-27 | 2002-11-26 | Chad Therapeutics, Inc. | Pneumatic oxygen conserving device |
EP1449559A1 (en) * | 2003-02-18 | 2004-08-25 | INO Therapeutics GmbH | Metered delivery of therapeutic gas |
US20040168686A1 (en) * | 2003-02-18 | 2004-09-02 | Christian Krebs | Metered administration of a therapeutic gas |
US6962154B2 (en) * | 2003-02-18 | 2005-11-08 | Ino Therapeutics Gmbh | Metered administration of a therapeutic gas |
US7617826B1 (en) | 2004-02-26 | 2009-11-17 | Ameriflo, Inc. | Conserver |
US8230859B1 (en) | 2004-02-26 | 2012-07-31 | Ameriflo, Inc. | Method and apparatus for regulating fluid |
US8146592B2 (en) | 2004-02-26 | 2012-04-03 | Ameriflo, Inc. | Method and apparatus for regulating fluid flow or conserving fluid flow |
US7448594B2 (en) | 2004-10-21 | 2008-11-11 | Ameriflo, Inc. | Fluid regulator |
US20090126734A1 (en) * | 2007-11-19 | 2009-05-21 | Allegiance Corporation | Respiratory therapy system with electromechanical driver |
US20090126731A1 (en) * | 2007-11-19 | 2009-05-21 | Allegiance Corporation | Patient interface assembly for respiratory therapy |
US8365727B2 (en) | 2007-11-19 | 2013-02-05 | Carefusion 2200, Inc. | Respiratory therapy system with electromechanical driver |
US8931478B2 (en) | 2007-11-19 | 2015-01-13 | Carefusion 2200, Inc. | Patient interface assembly for respiratory therapy |
US10195381B2 (en) | 2007-11-19 | 2019-02-05 | Vyaire Medical Consumables Llc | Patient interface assembly for respiratory therapy |
US11850077B2 (en) | 2012-05-30 | 2023-12-26 | Resmed Sensor Technologies Limited | Method and apparatus for monitoring cardio-pulmonary health |
US20200215278A1 (en) * | 2012-06-26 | 2020-07-09 | Resmed Sensor Technologies Limited | Methods and apparatus for monitoring and treating respiratory insufficiency |
US11786678B2 (en) * | 2012-06-26 | 2023-10-17 | Resmed Sensor Technologies Limited | Methods and apparatus for monitoring and treating respiratory insufficiency |
Also Published As
Publication number | Publication date |
---|---|
ATE38780T1 (en) | 1988-12-15 |
JPS60222066A (en) | 1985-11-06 |
EP0149722A3 (en) | 1986-07-16 |
EP0149722A2 (en) | 1985-07-31 |
JPH0263018B2 (en) | 1990-12-27 |
DE3475271D1 (en) | 1988-12-29 |
JPS60160968A (en) | 1985-08-22 |
BR8500182A (en) | 1985-08-27 |
DE3401841C2 (en) | 1988-06-30 |
EP0149722B1 (en) | 1988-11-23 |
DE3401841A1 (en) | 1985-07-25 |
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