US3910103A - Medical apparatus for measuring blood sedimentation - Google Patents

Medical apparatus for measuring blood sedimentation Download PDF

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Publication number
US3910103A
US3910103A US471563A US47156374A US3910103A US 3910103 A US3910103 A US 3910103A US 471563 A US471563 A US 471563A US 47156374 A US47156374 A US 47156374A US 3910103 A US3910103 A US 3910103A
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US
United States
Prior art keywords
pipette
container
medical apparatus
volume
beaker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US471563A
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English (en)
Inventor
Ewald Rose
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
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Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19732326136 external-priority patent/DE2326136C3/de
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of US3910103A publication Critical patent/US3910103A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/15003Source of blood for venous or arterial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150053Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150061Means for enhancing collection
    • A61B5/150099Means for enhancing collection by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150206Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150229Pumps for assisting the blood sampling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150389Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150374Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381Design of piercing elements
    • A61B5/150503Single-ended needles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150755Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/153Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04Investigating sedimentation of particle suspensions
    • G01N15/05Investigating sedimentation of particle suspensions in blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150992Blood sampling from a fluid line external to a patient, such as a catheter line, combined with an infusion line; blood sampling from indwelling needle sets, e.g. sealable ports, luer couplings, valves

Definitions

  • the volume of the beaker like container is approximately double 5 References Cited the volume of the pipette.
  • the pipette is marked with UNITED STATES PATENTS graduamns- 3,373,601 3/1968 Monn 73/6l.4 3 Claims, 1 Drawing Figure U.S. Patent Oct. 7,1975
  • the invention relates to an apparatus for measuring blood sedimentation utilizing a pipette which is provided with a transparent wall and graduations.
  • An object of the invention is, therefore, to provide an apparatus for blood-sedimentation measurements which is simple in its construction, safe to operate and cheap to produce.
  • the invention accordingly provides medical apparatus for measuring blood sedimentation including a pipette which is provided with a transparent wall and a scale of graduations marked thereon.
  • the outlet end of the pipette carries a radially outwardly projecting annular flange.
  • the outlet end has an outlet aperture and projects into a beaker-like container whose inner wall surrounds said annular flange tightly.
  • the container has adjacent to its upper edge internal stop dogs or a stop ring.
  • the beaker volume from its base to the stop dogs or stop ring is at least twice as great as the pipette volume.
  • the inlet end of the pipette may carry a cone or connector to which a tube can be connected.
  • FIGURE of the drawing is an axial section through the test apparatus according to the invention.
  • the DESCRIPTION OF PREFERRED EN[BODIMENT Medical apparatus for blood-sedimentation measurements comprises a sedimentation pipette l.
  • the sedimentation pipette preferably has a bore of 3 mm diameter and a wall thickness of 2 mm.
  • the sedimentation pipette is made from a transparent material, for example, glass or an extruded transparent plastic material.
  • the wall of the sedimentation pipette is marked with a scale from O to 200 mm. Above the mark an excess contents space can be provided, but such space can be comparatively small since suction on the pipette is not performed with the mouth.
  • the pipette carries a connector 2 for the connection of a tube, not shown, for supplying fluid to the pipette.
  • This connector can be applied as a press-fit or shrink-fit cap or be fastened into the bore of the pipette.
  • The: connector can be made from the same material as the pipette or of a different material.
  • the pipette At its lowerend or outlet, the pipette has an radially outwardly projecting annular flange 3.
  • the lower end of the pipette projects into a beaker-like container 4 which serves as a suction, mixing and pressure container.
  • the inner wall of the beaker-like container 4 tightly surrounds the annular flange 3, so that the flange acts as a sealing ring.
  • the interior wall of the beaker-like container 4 Near its upper, open end, the interior wall of the beaker-like container 4 carries a stop ring 5 or stop dogs.
  • the volume of the beakerlike container 4 from the base to the stop dogs or stop ring 5 is at least double the volume of the pipette.
  • An annular mark 6 indicates the point which, measured from the upper end of the pipette, marks 20% of the total volume of the pipette.
  • the annular mark 6 is at 44 mm when the overall length of the pipette is 220 mm.
  • a blood sedimentation test can be carried out with the apparatus in accordance with the invention as follows:
  • a tube is attached to the pipette connector 2, with flange 3 located in the bottom of container 4 as shown in the drawing; and sodium citrate solution is supplied to the pipette up to the annular mark 6 using suction created by pulling the beaker-like container 4. Then the doctor pierces the vein of the patient and completely fills the pipette by further pulling the beaker-like container.
  • the flange 3 acts like a piston and forms an air-tight seal with the inner wall of the beaker-like container 4. Now the doctor takes the cannula out of the vein of the patient to stop supply of blood to the pipette.
  • the pipette With an inside diameter of the pipette of 3 mm and a length of 220 mm, the pipette has an overall volume of 1.55 ml. If the beaker-like container 4 has an inside diameter of 10 mm, then when the length of the beaker-like container is 31.5 mm, from the base to the stop dogs, the beaker volume corresponds to double the pipette volume.
  • the doctor pulls the container 4 until flange 3 engages the stop so that the fluid in the pipette is transferred to the beaker-like container so that the beaker-like container contains the mixture of blood and sodium citrate solution.
  • the beaker-like container is only half full if the beaker-like container holds double the volume of the pipette.
  • the blood and the sodium citrate solution become intimately mixed.
  • the end of the pipette is then pushed downwards into the beaker-like container until the blood mixture rises up to the mark 0 in the pipette.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Manufacturing & Machinery (AREA)
  • Pain & Pain Management (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
US471563A 1973-05-23 1974-05-20 Medical apparatus for measuring blood sedimentation Expired - Lifetime US3910103A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732326136 DE2326136C3 (de) 1973-05-23 Medizinisches Gerät für Blutsenkungsmessungen

Publications (1)

Publication Number Publication Date
US3910103A true US3910103A (en) 1975-10-07

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ID=5881820

Family Applications (1)

Application Number Title Priority Date Filing Date
US471563A Expired - Lifetime US3910103A (en) 1973-05-23 1974-05-20 Medical apparatus for measuring blood sedimentation

Country Status (4)

Country Link
US (1) US3910103A (xx)
FR (1) FR2230995B1 (xx)
GB (1) GB1442278A (xx)
SE (1) SE400703B (xx)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4045175A (en) * 1975-12-10 1977-08-30 Ragnar Weber Micro-method of erythrocyte sedimentation
FR2400198A1 (fr) * 1977-08-11 1979-03-09 Braun Melsungen Ag Dispositif pour la determination de la vitesse de sedimentation de globules rouges du sang
US4200434A (en) * 1977-02-24 1980-04-29 Sanki Engineering Ltd. Immunological blood test method
JPS5637560A (en) * 1979-09-01 1981-04-11 Sarstedt Kunststoff Blood precipitation device
US4267723A (en) * 1979-07-19 1981-05-19 Mull John D Method of introducing a liquid into a measuring tube
US4622847A (en) * 1982-11-05 1986-11-18 L.P. Italiana S.P.A. Apparatus for measuring the rate of erythrosedimentation of the blood
US4669486A (en) * 1984-01-20 1987-06-02 Anders Trell Device for taking and dispensing blood samples for the purpose of determining blood sedimentation
AU633975B2 (en) * 1989-09-26 1993-02-11 Walter Sarstedt Blood extraction device
EP1218718A1 (en) * 1999-08-05 2002-07-03 Brian William King Direct aspiration-reaction and injection device and methods of use
US20040185570A1 (en) * 2003-03-21 2004-09-23 Bouboulis Denis A. Erythrocyte sedimentation rate (ESR) test measurement instrument of unitary design and method of using the same
US20060216829A1 (en) * 2003-03-21 2006-09-28 Denis Bouboulis Erythrocyte sedimentation rate (ESR) test measurement instrument of unitary design and method of using the same
US20180036725A1 (en) * 2016-08-08 2018-02-08 Nalge Nunc International Corporation Capillary transfer pipettes and related methods

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE381577B (sv) * 1974-06-24 1975-12-15 Mediplast Ab Anordning for overforing av en vetska, sasom blod fran en cylindrisk behallare till en pipett
DE3270054D1 (en) * 1981-02-10 1986-04-30 Dematex Dev & Invest Blood collection unit

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3373601A (en) * 1964-08-05 1968-03-19 Monn Stanislaus Device for the analysis of the sinking speed of blood corpuscles in a calibrated tube
US3718133A (en) * 1971-01-12 1973-02-27 Damon Corp Container unit for liquid samples

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2102785A (en) * 1935-10-18 1937-12-21 Brooks Clyde Method of and apparatus for sedimentation testing of blood

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3373601A (en) * 1964-08-05 1968-03-19 Monn Stanislaus Device for the analysis of the sinking speed of blood corpuscles in a calibrated tube
US3718133A (en) * 1971-01-12 1973-02-27 Damon Corp Container unit for liquid samples

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4045175A (en) * 1975-12-10 1977-08-30 Ragnar Weber Micro-method of erythrocyte sedimentation
US4200434A (en) * 1977-02-24 1980-04-29 Sanki Engineering Ltd. Immunological blood test method
FR2400198A1 (fr) * 1977-08-11 1979-03-09 Braun Melsungen Ag Dispositif pour la determination de la vitesse de sedimentation de globules rouges du sang
US4267723A (en) * 1979-07-19 1981-05-19 Mull John D Method of introducing a liquid into a measuring tube
JPS5637560A (en) * 1979-09-01 1981-04-11 Sarstedt Kunststoff Blood precipitation device
JPH023140B2 (xx) * 1979-09-01 1990-01-22 Baruteru Zarushutetsuto Kunsutoshutotsura Supuritsutsugusu Beruku
US4622847A (en) * 1982-11-05 1986-11-18 L.P. Italiana S.P.A. Apparatus for measuring the rate of erythrosedimentation of the blood
US4669486A (en) * 1984-01-20 1987-06-02 Anders Trell Device for taking and dispensing blood samples for the purpose of determining blood sedimentation
AU633975B2 (en) * 1989-09-26 1993-02-11 Walter Sarstedt Blood extraction device
EP1218718A1 (en) * 1999-08-05 2002-07-03 Brian William King Direct aspiration-reaction and injection device and methods of use
EP1218718A4 (en) * 1999-08-05 2003-04-02 Brian William King DIRECT INJECTION AND SUCTION-REACTION DEVICE AND METHODS OF USE THEREOF
US20040185570A1 (en) * 2003-03-21 2004-09-23 Bouboulis Denis A. Erythrocyte sedimentation rate (ESR) test measurement instrument of unitary design and method of using the same
US6974701B2 (en) 2003-03-21 2005-12-13 Hemovations, Llc Erythrocyte sedimentation rate (ESR) test measurement instrument of unitary design and method of using the same
US20060030051A1 (en) * 2003-03-21 2006-02-09 Bouboulis Denis A Erythrocyte sedimentation rate (ESR) test measurement instrument of unitary design and method of using the same
US20060216829A1 (en) * 2003-03-21 2006-09-28 Denis Bouboulis Erythrocyte sedimentation rate (ESR) test measurement instrument of unitary design and method of using the same
US20180036725A1 (en) * 2016-08-08 2018-02-08 Nalge Nunc International Corporation Capillary transfer pipettes and related methods
US10814320B2 (en) * 2016-08-08 2020-10-27 Nalge Nunc International Corporation Capillary transfer pipettes and related methods

Also Published As

Publication number Publication date
FR2230995A1 (xx) 1974-12-20
DE2326136B2 (de) 1976-06-16
DE2326136A1 (de) 1974-12-12
FR2230995B1 (xx) 1979-08-03
SE400703B (sv) 1978-04-10
GB1442278A (en) 1976-07-14

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