US3905366A - Injection syringe with shiftable comparison indicator - Google Patents

Injection syringe with shiftable comparison indicator Download PDF

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Publication number
US3905366A
US3905366A US384706A US38470673A US3905366A US 3905366 A US3905366 A US 3905366A US 384706 A US384706 A US 384706A US 38470673 A US38470673 A US 38470673A US 3905366 A US3905366 A US 3905366A
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United States
Prior art keywords
piston
ring
shifting
cylinder
injection syringe
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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US384706A
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English (en)
Inventor
George Edgar Callahan
Lothar Barensfeld
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Individual
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Individual
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525—Dosing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3125—Details specific display means, e.g. to indicate dose setting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3125—Details specific display means, e.g. to indicate dose setting
    • A61M2005/3126—Specific display means related to dosing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/285—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
    • A61M5/288—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened by piercing without internal pressure increase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps

Definitions

  • the present invention relates to an injection syringe, and more particularly to a syringe having means for determining the quantity delivered during injection, particularly partial quantities of a complete filling.
  • this problem is resolved by arranging a scale and/or an index or comparison mark so that the same are relatively displaceable with respect to each other and resettable to zero before each injection.
  • the invention may also be advantageously used immediately for the delivery of medications by means of injection syringes or for dosing the components when composing infusion and rinsing solutions.
  • injection syringes it is possible to use all known types of injection syringes as well as ready-for-use syringes or phials' which are to be used immediately as syringe cylinders and can be placed into syringe frames.
  • the arrangement of the scale and of the comparison mark may either be provided on the phial carrier or, advantageously, directly on the phial.
  • the new syringe may be used with particular advantage for composing infusion or rinsing solutions if in combination with the scale settable to zero, the scale division itself, instead of being gauged in volume units, is gauged in direct proportionality with the composition of the syringe contents.
  • Possible scale divisions may particularly be: Weight units of dissolved substances, insulin, vitamin, etc. units, molar units, milliequivalents (mval), cation and/or anion units etc.
  • the present invention may be realized in a particularly simple manner in injection syringes with a transparent cylinder if the scale is displaceable on a scale support extending in the longitudinal direction of the cylinder.
  • the comparison mark may then preferably be provided directly on the piston.
  • Such a scale arrangement may, for example, be achieved by tubular segmental scale supports which may also be stacked subsequently onto conventional cylinders.
  • a simple realization is also possible if the scale is arranged on a stripeshaped scale support shaped as a tubular segment encircling the cylinder by at least more than 180, for example, which is fixed in a holder provided on the cylinder to be shiftable in the longitudinal direction thereof.
  • the invention can be realized advantageously if the scale support is arranged in the piston rod and if the latter comprises a stop member for fixing the comparison mark in zero position upon extraction of the piston rod or upon shifting the comparison mark towards the cylinder. It is particularly simple in this way to achieve automatic resetting of the comparison mark to zero during insertion of the piston rod into the piston of the full or partially emptied phial by former injections.
  • Such a device may be realized in a particularly simple manner if the holder is a transparent tube in engagement with the syringe cylinder, the holder having frictionally supported therein a ring encircling the piston rod and bearing a comparison or index mark, and if the stop device is a complementary gearing provided in segments on the inside of the tube or on the outside of the comparison mark, which can be engaged or disengaged by rotation of the ring.
  • Engaging or disengaging of the stop device is achieved in a most simple way by rotation of the tube or the comparison mark provided as a support.
  • the ring of the comparison mark may also thus be arranged longitudinally on the piston rod so that rotation of the latter engages or disengages the gearing of the comparison mark ring and the tube.
  • the stop device is made adjustable.
  • FIG. 1 is a fragmentary view, partially in cross section, illustrating an injection phial of a type contemplated
  • FIG. 4a is a partial sectional view taken through an injection syringe with automatic resetting to zero;
  • FIG. 4b is a cross section through the injection syringe of FIG. 4a;
  • FIG. is a partial sectional view through a further modified embodiment of the invention.
  • FIG. 6 is a modified embodiment of the injection syringe of FIG. 2.
  • an injection phial comprises a cylinder 1 which in a known manner is provided for insertion into a known syringe frame and is sealed on one end with a plug 2 having a puncture location 2a for the needle, as well by a second plug serving as a piston 3.
  • the transparent cylinder 1 is encircled by a tubular scale carrier 4.
  • the scale carrier 4 is frictionally arranged on the cylinder 1 such that the zero value may be brought in line with the front edge of piston 3 before starting the injection by shifting the scale 5, as indicated by the double-headed arrow.
  • FIG. 1a shows a scale support 4 with a modified scale division which, in combination with the zero position of the beginning of the scale according to the present invention, is especially suitable for the composition of rinsing and infusion solutions.
  • the shown scale range corresponds to a cylinder filling of 30 ml containing 162.5 mmol NaCl in aqueous solution.
  • the concentration obtained may be read without any calculation and without difficulties from scale 5b.
  • concentrations such as I40. 77, 70, 50, 35 or mmol/l may in this way be composed most easily even by inexperienced personnel.
  • an appropriate selection of the scale division and/or solution concentration makes it possible to compose any combinations.
  • the analogous scale division may be effected in milliequivalent cation or anion or in vitamin units so that individual composition of such solutions is possible'without difficulty. By resetting the scales to zero after each injection. several deliveries from the phials may be effected economically and without any danger of improper dosage due to a mistake in calculation.
  • FIG. 2 shows a syringe phial with a cylinder 1 ready for use on one end of which there has been placed a device 12. The function can be seen from FIGS. 2a
  • the ring 11 Before injection. the ring 11 is shifted to the end of the handle 8 by pressure on the piston rod 9. Because of frictional engagement with the handle 8, the ring 11 remains in this position until it is shifted by stop device 12 during insertion of the piston rod 9 into piston 3. According to FIG. 2b, the special arrangement of the stop assures that the scale is compulsorily reset to zero before beginning an injection. As shown in FIG. 20, the exact reading of the dispensed partial quantity is made possible during injection.
  • FIG. 3a shows a partial section through a modified embodiment of the invention in which the ring 11, which carries the comparison mark 10, is biased against stop device 12 by spring 13.
  • the handle 8 and the ring 11 are provided according to FIG. 3b with complementary gearings 16, 16a in segments so that the ring may selectively be engaged with or disengaged from the handle 8 by rotation around its axis.
  • the piston rod 9 and the ring 11 are then engaged via grooves 17 and projections 18 so that rotation of the ring 11 and therefore engagement or disengagement of the handle 8 can be obtained by rotation of the piston rod 9.
  • the chosen arrangement makes it possible to disengage the ring 11 from the handle 8 before each injection by rotation of the piston rod 9 so that, because of biasing by spring 13, zero position of the comparison mark 10 on the stop device 12 is obtained.
  • Rotation of the piston rod 9 then re-engages the gearing 16 so that ring 11 is locked against the biasing tension of spring 13 and the piston advance during injection can be read by comparison of the position of scale 5 with the position of the comparison mark 10.
  • the rotation of piston rod 9 again effects resetting to zero in a simple manner, whereby it is again possible in the next injection to effect readings starting with zero.
  • FIGS. 4a and 4b showan injection syringe in which a transparent inner tube having inner gear segments is rotatably supported in a transparent handle.
  • the phialside end of the inner tube 14 preventing rotation with respect to the inserted cylinder 1, for example by means of cams or the friction surface 15.
  • the ring 11, gearing in segments on the outside and transparent at least within the range of the comparison mark 10 comprises a spring 13 pressing against the back end of the inner tube.
  • the piston rod 9 with scale 5 is provided with one or several longitudinal grooves 17 the front ends of which are stop devices of safety elements for the index support to prevent relative rotation thereof and furthermore to assure the transmission of the rotation of the handle 8 to the piston rod 9 by means of the cams 23 of the handle. and therefore also to the ring 11 and to the comparison mark 10.
  • the pressure spring 13 brings ring 11, and therefore comparison mark 10 as well as piston rod 9, into its original position according to FIG. 2a.
  • the piston rod 9 and the ring 11 are shifted backwards into zero position. and a tight connection is created between cylinder 1 and inner tube 14.
  • the movement of rotation with which the handle 8 and the cylinder 1 are locked by bayonet holder 24, is transmitted to the piston rod 9 and the ring 11 which is longitudinally fixed by the outer gearing 16 now entering into engagement with the inner gearing 16a of the inner tube 14.
  • the procedure is now prosecuted as shown in FIG. 20. Resetting to zero is effected by spring 13 upon disengaging and re-engaging the handle 8 with the partially emptied cylinder l, i.e. by two opposite rotational movements of the handle 8 with respect to the inner tube 14 fixed on cylinder 1.
  • FIG. 5 shows an injection syringe which constructively corresponds to the example of FIG. 3 to a great extent.
  • a resiliently biased stop device 19 which is engaged with ring 11 through an opening in the handle 8. The zero position of scale 5 and of comparison mark is possible in a simple manner by temporarily disengaging the stop device 19.
  • FIG. 6 shows an injection syringe the construction of which approximately corresponds to the example of FIG. 2.
  • the stop device of ring 11 has not been shown, but of course any such device, for example those of FIGS. 3, 4 or 5, may be provided.
  • the piston rod 9 is provided with an outer threading 21 so that a screwnut with inner threading provided as stop device 22 can be adjusted by choice.
  • the stop device 22 becomes engaged with the comparison mark during advance of the piston, whereby further injection is stopped upon corresponding stopping of ring 11 by means of handle 8.
  • the quantity to be delivered may consequently be thus preselected by correspondingly adjusting the stop device 22 so that it cannot be exceeded during injection once the desired quantity has been preselected.
  • the ring 11 of the chosen construction serves to lock the stop device 22 and also to support the comparison mark 10.
  • a separate element may be provided instead without departing from the scope of the present invention.
  • Injection syringe comprising cylinder means having a closed end receiving one end of a cannula therethrough, a piston in said cylinder means, means for shifting said piston longitudinally in said cylinder means to dispense a dose of fluid from said cylinder through the cannula, a dosage scale associated with said means for shifting said piston, and a dosage comparison indicator positioned in a portion of said cylinder means to indicate the dosage discharged upon movement of said piston in said cylinder means, said indicator being shiftable in said cylinder to reset the dosage indication at the starting point after each discharge.
  • the means for shifting the piston comprises a stop device for moving the comparison indicator into zero position upon insertion of the means for shifting the piston into the piston.
  • said portion of the cylinder means comprises a transparent tubular extension of the cylinder means
  • said comparison indicator comprises a ring encircling the means for shifting the piston and in that the stop means is a complementary gearing provided in segments on the inside of the tubular extension and the outside of said ring which can be engaged or disengaged by rotation of the ring.
  • the comparison indicator comprises a ring encircling the means for shifting the piston
  • the stop device is a lever passing through the tubular extension for ratchet engagement with the surface of the ring with the comparison indicator directed in one direction.
  • the means for shifting the piston comprises at least one limit stop at a distance corresponding to a predetermined partial dosage, the stop being indirectly engageable with the cylinder means during discharge. wherefore the piston advance is locked after delivery of the predetermined partial dosage.

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
US384706A 1972-08-03 1973-08-01 Injection syringe with shiftable comparison indicator Expired - Lifetime US3905366A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1153272A CH548212A (de) 1972-08-03 1972-08-03 Injektionsspritze.

Publications (1)

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US3905366A true US3905366A (en) 1975-09-16

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US384706A Expired - Lifetime US3905366A (en) 1972-08-03 1973-08-01 Injection syringe with shiftable comparison indicator

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US (1) US3905366A (US06544258-20030408-M00015.png)
CH (1) CH548212A (US06544258-20030408-M00015.png)
DE (1) DE2337659A1 (US06544258-20030408-M00015.png)
FR (1) FR2194452B3 (US06544258-20030408-M00015.png)
GB (1) GB1431846A (US06544258-20030408-M00015.png)
IT (1) IT990054B (US06544258-20030408-M00015.png)

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4102451A (en) * 1977-05-25 1978-07-25 Eli Lilly And Company Mixing vial
US4973318A (en) * 1988-02-10 1990-11-27 D.C.P. Af 1988 A/S Disposable syringe
US5112317A (en) * 1988-01-22 1992-05-12 Nosta Ag Injection device
EP1000631A3 (de) * 1997-03-03 2000-06-07 Medico Development Investment Company Injektionsgerät
EP1273348A2 (en) * 2001-07-03 2003-01-08 Miles Athol Blackwood-Sewell Graduated pipette
US20040230157A1 (en) * 2003-05-16 2004-11-18 Perry Stephen J. Fluid delivery system and related methods of use
US20070175058A1 (en) * 2006-01-31 2007-08-02 Philip Morris Usa Inc. Tool for identifying non-conformities
US20090247985A1 (en) * 2008-03-25 2009-10-01 Cook Incorporated Embolic particle mixing syringe
US20090264815A1 (en) * 1989-08-04 2009-10-22 Grogan Jr Jack Raymond Dose calculating dispenser using a body weight scale on a medicine dropper
EP2201973A1 (en) * 2008-12-23 2010-06-30 Sanofi-Aventis Deutschland GmbH Drug delivery device with piston rod carrying dose markings
US20100179485A1 (en) * 2004-12-01 2010-07-15 Novo Nordisk A/S Injection device
US20120029443A1 (en) * 2009-04-03 2012-02-02 Shl Group Ab Medicament Delivery Device
US20120071836A1 (en) * 2009-04-30 2012-03-22 Sanofi-Aventis Deutschland Gmbh Drive mechanism for a drug delivery device
CN102510762A (zh) * 2009-09-23 2012-06-20 赛诺菲-安万特德国有限公司 用于药物输送装置的组件和药物输送装置
US20170043099A1 (en) * 2009-09-23 2017-02-16 Sanofi-Aventis Deutschland Gmbh Assembly and indicator for a drug delivery device

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2535206B1 (fr) * 1982-11-03 1989-06-09 Micro Mega Sa Seringue dentaire pour injections intra-ligamentaires
EP0109913A3 (fr) * 1982-11-03 1984-09-12 Micro-Mega Seringue dentaire pour injections intra-ligamentaires
FR2556595B2 (fr) * 1983-12-20 1989-07-13 Micro Mega Sa Seringue dentaire pour injections intra-ligamentaires
IT1217595B (it) * 1988-05-13 1990-03-30 Molteni & C Dispositivo anticontagio per iniezione di soluzioni anestetiche odontoiatriche contenute in cartuccia
PT89148A (pt) * 1988-12-02 1990-06-29 Roseiro Antonio H Seringa em material plastico, para tratamentos dentarios
US5328486A (en) * 1991-11-19 1994-07-12 American Cyanamid Company Syringe for dispensing multiple dosages
WO2007109002A1 (en) * 2006-03-13 2007-09-27 Merial Limited Adjustable dosage syringe with dose volume scale disposed along the longitudinal axis of the plunger
DE202009011284U1 (de) * 2009-08-19 2010-03-25 Sprenger, Klaus, Dr. Dosierringe für fraktionierte Medikamentengabe aus Einmalspritzen in der Palliativmedizin
DE102014201393A1 (de) * 2014-01-27 2015-07-30 Henke-Sass, Wolf Gmbh Spritze

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US1304327A (en) * 1919-05-20 Dispensinfg and measuring apparatus fob lubricants and the
US1832436A (en) * 1928-06-18 1931-11-17 Mark Isaacs Graduated protector for cylinders and the like
US2375711A (en) * 1941-10-28 1945-05-08 Vondrak Joseph Syringe
US2523850A (en) * 1947-12-11 1950-09-26 Steinberg Nathan Medical syringe and process
US2626087A (en) * 1947-10-29 1953-01-20 Alfred S Howard Syringe with vernier adjustment
US2736315A (en) * 1954-03-23 1956-02-28 James F Feeney Hypodermic syringe piston and actuating stem assembly
US2739588A (en) * 1954-10-06 1956-03-27 Donald E Yochem Hypodermic syringe gauge
US3150524A (en) * 1961-02-20 1964-09-29 Gen Controls Co Adjustable scale for manometer
US3327900A (en) * 1965-01-27 1967-06-27 Greiner Scient Corp Liquid dispensing device
US3730389A (en) * 1971-06-22 1973-05-01 Precision Sampling Corp Syringe

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1304327A (en) * 1919-05-20 Dispensinfg and measuring apparatus fob lubricants and the
US1832436A (en) * 1928-06-18 1931-11-17 Mark Isaacs Graduated protector for cylinders and the like
US2375711A (en) * 1941-10-28 1945-05-08 Vondrak Joseph Syringe
US2626087A (en) * 1947-10-29 1953-01-20 Alfred S Howard Syringe with vernier adjustment
US2523850A (en) * 1947-12-11 1950-09-26 Steinberg Nathan Medical syringe and process
US2736315A (en) * 1954-03-23 1956-02-28 James F Feeney Hypodermic syringe piston and actuating stem assembly
US2739588A (en) * 1954-10-06 1956-03-27 Donald E Yochem Hypodermic syringe gauge
US3150524A (en) * 1961-02-20 1964-09-29 Gen Controls Co Adjustable scale for manometer
US3327900A (en) * 1965-01-27 1967-06-27 Greiner Scient Corp Liquid dispensing device
US3730389A (en) * 1971-06-22 1973-05-01 Precision Sampling Corp Syringe

Cited By (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4102451A (en) * 1977-05-25 1978-07-25 Eli Lilly And Company Mixing vial
US5112317A (en) * 1988-01-22 1992-05-12 Nosta Ag Injection device
US4973318A (en) * 1988-02-10 1990-11-27 D.C.P. Af 1988 A/S Disposable syringe
US20090264815A1 (en) * 1989-08-04 2009-10-22 Grogan Jr Jack Raymond Dose calculating dispenser using a body weight scale on a medicine dropper
EP1000631A3 (de) * 1997-03-03 2000-06-07 Medico Development Investment Company Injektionsgerät
EP1273348A2 (en) * 2001-07-03 2003-01-08 Miles Athol Blackwood-Sewell Graduated pipette
EP1273348A3 (en) * 2001-07-03 2004-03-10 Miles Athol Blackwood-Sewell Graduated pipette
US6837119B2 (en) 2001-07-03 2005-01-04 Miles Athol Blackwood-Sewell Pipettes
US20040230157A1 (en) * 2003-05-16 2004-11-18 Perry Stephen J. Fluid delivery system and related methods of use
US8628555B2 (en) 2003-05-16 2014-01-14 Boston Scientific Scimed, Inc. Fluid delivery system and related methods of use
US7641668B2 (en) 2003-05-16 2010-01-05 Scimed Life Systems, Inc. Fluid delivery system and related methods of use
US8147511B2 (en) 2003-05-16 2012-04-03 Boston Scientific Scimed, Inc. Fluid delivery system and related methods of use
US9855391B2 (en) 2004-12-01 2018-01-02 Novo Nordisk A/S Injection device
US20100179485A1 (en) * 2004-12-01 2010-07-15 Novo Nordisk A/S Injection device
US8444606B2 (en) 2004-12-01 2013-05-21 Novo Nordisk A/S Injection device
US20070175058A1 (en) * 2006-01-31 2007-08-02 Philip Morris Usa Inc. Tool for identifying non-conformities
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Also Published As

Publication number Publication date
DE2337659A1 (de) 1974-03-14
CH548212A (de) 1974-04-30
IT990054B (it) 1975-06-20
GB1431846A (en) 1976-04-14
FR2194452B3 (US06544258-20030408-M00015.png) 1976-07-16
FR2194452A1 (US06544258-20030408-M00015.png) 1974-03-01

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