US3876378A - Analytic device utilizing a reaction-sensitive chemical product - Google Patents
Analytic device utilizing a reaction-sensitive chemical product Download PDFInfo
- Publication number
- US3876378A US3876378A US355087A US35508773A US3876378A US 3876378 A US3876378 A US 3876378A US 355087 A US355087 A US 355087A US 35508773 A US35508773 A US 35508773A US 3876378 A US3876378 A US 3876378A
- Authority
- US
- United States
- Prior art keywords
- vessel
- enclosure
- disc
- groove
- side walls
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000126 substance Substances 0.000 title claims abstract description 37
- 238000006243 chemical reaction Methods 0.000 title description 2
- 239000007788 liquid Substances 0.000 claims abstract description 21
- 239000000463 material Substances 0.000 claims abstract description 21
- 239000002250 absorbent Substances 0.000 claims abstract description 10
- 230000002745 absorbent Effects 0.000 claims abstract description 10
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 10
- 230000002093 peripheral effect Effects 0.000 claims abstract description 9
- 238000006073 displacement reaction Methods 0.000 claims abstract description 6
- 238000004458 analytical method Methods 0.000 claims description 17
- 238000004873 anchoring Methods 0.000 claims description 4
- 230000000284 resting effect Effects 0.000 claims description 4
- 238000010276 construction Methods 0.000 description 4
- 238000005188 flotation Methods 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 102000015439 Phospholipases Human genes 0.000 description 1
- 108010064785 Phospholipases Proteins 0.000 description 1
- 102000045595 Phosphoprotein Phosphatases Human genes 0.000 description 1
- 108700019535 Phosphoprotein Phosphatases Proteins 0.000 description 1
- 102000003929 Transaminases Human genes 0.000 description 1
- 108090000340 Transaminases Proteins 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000007667 floating Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
Definitions
- the device includes a generally tubular, upright vessel open at its upper end and having a closed lower end.
- a flange extending around the interior of the vessel closely above its lower end defines a groove about the lower interior region of the vessel.
- An annular disc of absorbent material impregnated with the chemical product rests against the lower end of the vessel with its outer peripheral edge snugly received within the groove so that the disc is prevented from displacement.
- a central opening may be provided within the disc to permit trapped air to escape when test liquid is added to the vessel.
- This invention relates to an analytic device of the type comprising a vessel in which is mounted a piece of absorbent material impregnated with an indicating reagent which undergoes a change, typically in color, when acted upon by a sample of liquid under analysis having a particular property to which the reagent is sensitive.
- one common form of test employs analysis materials comprising absorbent material (typically paper) impregnated with chemical products sensitive to the chemical or biological analysis being performed.
- Such products include reagents which change color dependent upon acidity or alkalinity, or upon the presence or absence of a particular chemical or biological substance to which they are sensitive.
- the user may be supplied with the impregnated material in disc or band form and with a tube in which the impregnated material is to be mounted, after which the liquid to be tested is introduced to the tube and applied to the material.
- the present invention provides an analytic device utilizing a reaction-sensitive chemical product, intended to obviate or minimize problems of the type previously discussed.
- an analytic device constructed in accordance with the present invention includes a generally tubular upright vessel open at its upper end and having a closed lower end.
- An internal flange defines a groove extending peripherally about the interior of the vessel adjacent its lower end.
- a disc of absorbent material impregnated with the sensitive chemical product rests against the lower end of the vessel with its outer peripheral edge snugly received within the groove.
- FIG. 1 is a cross sectional, side view of an analytic device constructed in accordance with the preferred embodiment of the invention.
- FIGS. 2-4 are cross sectional side views showing three alternative embodiments of the construction of the analytic device.
- FIG. 1 of the drawings an analytic device constructed in accordance with the preferred embodiment of the invention is there shown.
- the device comprises an upright vessel 10 having an open upper end, a vertical tubular sidewall and a closed, flat horizontal lower end 11.
- An annular flange 12 fixedly secured to the vertical tubular sidewall of the vessel 10 extends peripherally around the interior thereof spaced closely above the lower end 11.
- the flange 12 and the lower end 11 together define a peripherally extending groove adjacent the lower end of the vessel and this groove snugly receives the outer peripheral edge of a flat horizontal disc 13.
- the disc 13 is made of absorbent material, such as paper, impregnated with a chemical product suitable for the contemplated analysis.
- the chemical product may for example be a reagent for metering the glucose in urine, or measuring an attack on protein by an enzyme.
- the disc 13 extends from closely adjacent the vertical sidewall of the vessel 10 inwardly of the flange 12 so that portions projecting inwardly of the flange are exposed to view. As the material to be tested is introduced in liquid form, the disc 13 will undergo a color or other change if the test material meets the required condition for activation of the chemical product with which the disc is impregnated and the change will be visible to the user.
- the flange 12 may be made of transparent material so that the color change of the disc may be more readily observed.
- test liquid may readily be introduced without difficulty.
- the mounting of the disc with its peripheral edge anchored within a groove, defined by the flange l2 and the lower end 11, ensures that the disc will not tend to be displaced upwardly within the vessel by flotation but will be retained in position.
- the disc 13 may be provided with a central opening which permits the free escape of air from beneath the disc so that air bubbles do not tend to become entrapped underneath it.
- the vessel 20 is made in two parts, a dish shaped lower end 5 containing an upwardly facing horizontal rim about its periphery and an open-ended upper tube containing a corresponding horizontal rim about its lower periphery.
- the flange comprises a plate 24 having a central opening with the outer portions of the plate being mounted between the rims of the upper and lower parts of the vessel which are fixedly connected together along an annular seam 6 by any conventional bonding or adhesive process.
- the disc 13 is mounted between the underside of the flange and the lower end.
- a third embodiment shown in FIG. 3 is generally similar to the second embodiment shown in FIG. 2 but with the difference that the lower end is flat and that the plate 14 configured as an inverted dish to provide a recessed space within the disc 13 is received.
- the vessel 40 is of upwardly and outwardly flared configuration and nestingly receives a correspondingly configured inner cup 7.
- the disc 13 is mounted between the lower ends of the cup and the vessel and extends radially inwardly of a central opening through the lower end of the inner cup.
- the vessel 40 and the inner cup 7 are provided with overlapping horizontal flanges connected together along a seam line 8.
- vessels may be of the generally round cross section as disclosed or may, alternatively, be of elongate, irregular, or any other desired cross section.
- An analysis vessel for holding fast therein a member impregnated with a reagent for analyzing a substance in a liquid to be placed in said vessel comprising:
- impregnated member may be at least par tially engaged in said groove and thereby anchored within said enclosure.
- tubular enclosure having a substantially circular cross-section b. said groove being of annular configuration and extending about the entire periphery of said enclosure for receiving and engaging therein the outer periphery of a disc-shaped impregnated member.
- the analysis vessel of claim 1 further comprising:
- said bottom of said enclosure being a member distinct from said side walls, said bottom member being dished downwardly over its central portion, defining a relieved portion therein, and
- said means for defining a groove comprising a substantially flat flange member sandwiched between said side walls and said bottom member, said flange member having an aperture in its central region over a portion of said relieved portion of said bottom member forming a flange extending inwardly from about the periphery of said side walls over a portion of said bottom member.
- the analysis vessel of claim 1 further comprising:
- said bottom of said enclosure being a substantially flat member distinct from said side walls
- said means for defining said groove comprising a flange member sandwiched between said side walls and said bottom member, said flange member being relieved upwardly over its central portion defining with said bottom member a groove about the bottom interior of said enclosure, said flange member also having an aperture in its central region.
- said means for defining a groove comprising a liner having a configuration substantially corresponding to that of said enclosure and being nestable within said enclosure in a position allowing spacing between the bottoms of said enclosure and said liner, said liner additionally having an aperture in its bottom, whereby the impregnated member can be held in the space between said bottoms of said enclosure and said liner, said aperture permitting communication between said impregnated member and the interior of said liner.
- An analytic device utilizing a chemical product for analyzing a substance in a liquid to be placed in said device, the device comprising:
- a. a generally tubular vessel having side walls and a bottom;
- a disc of absorbent material impregnated with the chemical product said disc being disposed within the vessel and resting against said bottom of said vessel with an outer peripheral edge of said disc snugly received within said groove thereby anchoring said disc against displacement relative to said vessel.
- analytic device wherein the means defining the groove being a flange forming an opening adjacent the center portion of the vessel and the disc of absorbent material having an aperture therein underlying the opening of the flange and providing a cavity within which the liquid with the substance to be analyzed can be viewed.
- An analysis vessel for holding fast therein a portion of material including a reagent for analyzing a substance in a liquid to be placed in said vessel comprising:
- portion of material may be at least partially engaged in said groove and thereby anchored within said enclosure.
- An analytic device utilizing a chemical product for analyzing a substance in a liquid to be placed in said device, the device comprising: 7
- said disc being disposed within the vessel and resting against said bottom of said vessel with an outer peripheral edge of said disc snugly received within said groove thereby anchoring said disc against displacement relative to said vessel.
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7218386A FR2185209A5 (enrdf_load_stackoverflow) | 1972-05-18 | 1972-05-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
US3876378A true US3876378A (en) | 1975-04-08 |
Family
ID=9098966
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US355087A Expired - Lifetime US3876378A (en) | 1972-05-18 | 1973-04-27 | Analytic device utilizing a reaction-sensitive chemical product |
Country Status (2)
Country | Link |
---|---|
US (1) | US3876378A (enrdf_load_stackoverflow) |
FR (1) | FR2185209A5 (enrdf_load_stackoverflow) |
Cited By (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4071320A (en) * | 1976-04-27 | 1978-01-31 | Martin Korbin | Device for the quantitative determination of impurities, especially bacteria, on flat surfaces |
US4125376A (en) * | 1977-04-22 | 1978-11-14 | The United States Of America As Represented By The Secretary Of The Army | Method for detecting water pollutants |
US4147752A (en) * | 1977-01-14 | 1979-04-03 | Kommandiittihytio Finnpipette Osmo A. Souvaniemi | Form piece for apparatuses used for immunoassays and enzyme reactions |
US4239853A (en) * | 1979-01-22 | 1980-12-16 | Bradley Rex L | Antibiotic testing method and apparatus having a channelized reservoir |
EP0490447A1 (en) * | 1990-12-10 | 1992-06-17 | Financieringsmaatschappij Sparrendaal I B.V. | A disposable liquid testing device |
US5440919A (en) * | 1994-08-29 | 1995-08-15 | Spectronics Corporation | Method of introducing leak detection dye into an air conditioning or refrigeration system |
DE19506802A1 (de) * | 1995-02-27 | 1996-08-29 | Karl Reichart | Reagensträger zur Zugabe von Reagentien |
US6070455A (en) * | 1995-07-21 | 2000-06-06 | Bright Solutions, Inc. | Leak detection additives |
USRE36951E (en) * | 1994-08-29 | 2000-11-14 | Spectronics Corporation | Method of introducing leak detection dye into an air conditioning or refrigeration system including solid or semi-solid fluorescent dyes |
US6314907B1 (en) | 1999-08-02 | 2001-11-13 | Optiva | Device use indicator |
US20020096643A1 (en) * | 1996-02-08 | 2002-07-25 | Bright Solutions, Inc., A Michigan Corporation | Portable light source and system for use in leak detection |
US6557484B1 (en) * | 2000-10-04 | 2003-05-06 | Jimmy Engelman | Device for sugar and/or caffeine content indication |
DE10164834B4 (de) * | 2001-12-04 | 2004-09-16 | Roche Diagnostics Gmbh | Aufnahme für Proben und Komplettfolie zum Aufnehmen von Proben |
US20050272844A1 (en) * | 2004-06-02 | 2005-12-08 | Westman Morton A | Leak detection materials and methods |
US7319037B1 (en) | 2002-05-14 | 2008-01-15 | Orit Albeck-Marom | Fluid tester and method of use |
WO2012087342A1 (en) * | 2010-12-22 | 2012-06-28 | Abramson Michael T | Apparatus for detection of a contaminated beverage and method for producing same |
US20120160725A1 (en) * | 2010-12-22 | 2012-06-28 | Abramson Michael T | System and method for detection of a contaminated beverage |
GB2493763A (en) * | 2011-08-18 | 2013-02-20 | Univ Cranfield | Microplates with Enhanced Immobilisation capabilities |
US9285352B2 (en) | 2010-12-22 | 2016-03-15 | Drinksavvy, Inc. | System and method for detection of a contaminated beverage |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3476515A (en) * | 1966-04-26 | 1969-11-04 | Du Pont | Analytical test pack and process for analysis |
US3477821A (en) * | 1967-12-26 | 1969-11-11 | Xerox Corp | Chemical package |
US3582283A (en) * | 1970-03-25 | 1971-06-01 | Xerox Corp | Chemical package |
US3689224A (en) * | 1966-04-13 | 1972-09-05 | Westinghouse Electric Corp | Chemical contaminant detection sampler |
US3740196A (en) * | 1971-03-30 | 1973-06-19 | Us Army | Chemical spot test system |
US3768974A (en) * | 1971-03-22 | 1973-10-30 | Sterilizer Control Royalties | Disposable colorimetric indicator device for measuring the concentration of chlorine in water |
-
1972
- 1972-05-18 FR FR7218386A patent/FR2185209A5/fr not_active Expired
-
1973
- 1973-04-27 US US355087A patent/US3876378A/en not_active Expired - Lifetime
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3689224A (en) * | 1966-04-13 | 1972-09-05 | Westinghouse Electric Corp | Chemical contaminant detection sampler |
US3476515A (en) * | 1966-04-26 | 1969-11-04 | Du Pont | Analytical test pack and process for analysis |
US3477821A (en) * | 1967-12-26 | 1969-11-11 | Xerox Corp | Chemical package |
US3582283A (en) * | 1970-03-25 | 1971-06-01 | Xerox Corp | Chemical package |
US3768974A (en) * | 1971-03-22 | 1973-10-30 | Sterilizer Control Royalties | Disposable colorimetric indicator device for measuring the concentration of chlorine in water |
US3740196A (en) * | 1971-03-30 | 1973-06-19 | Us Army | Chemical spot test system |
Cited By (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4071320A (en) * | 1976-04-27 | 1978-01-31 | Martin Korbin | Device for the quantitative determination of impurities, especially bacteria, on flat surfaces |
US4147752A (en) * | 1977-01-14 | 1979-04-03 | Kommandiittihytio Finnpipette Osmo A. Souvaniemi | Form piece for apparatuses used for immunoassays and enzyme reactions |
US4125376A (en) * | 1977-04-22 | 1978-11-14 | The United States Of America As Represented By The Secretary Of The Army | Method for detecting water pollutants |
US4239853A (en) * | 1979-01-22 | 1980-12-16 | Bradley Rex L | Antibiotic testing method and apparatus having a channelized reservoir |
EP0490447A1 (en) * | 1990-12-10 | 1992-06-17 | Financieringsmaatschappij Sparrendaal I B.V. | A disposable liquid testing device |
USRE36951E (en) * | 1994-08-29 | 2000-11-14 | Spectronics Corporation | Method of introducing leak detection dye into an air conditioning or refrigeration system including solid or semi-solid fluorescent dyes |
US5440919A (en) * | 1994-08-29 | 1995-08-15 | Spectronics Corporation | Method of introducing leak detection dye into an air conditioning or refrigeration system |
US5650563A (en) * | 1994-08-29 | 1997-07-22 | Spectronics Corporation | Method of introducing leak detection dye into an air conditioning or refrigeration system including solid or semi-solid fluorescent dyes |
DE19506802A1 (de) * | 1995-02-27 | 1996-08-29 | Karl Reichart | Reagensträger zur Zugabe von Reagentien |
US6070455A (en) * | 1995-07-21 | 2000-06-06 | Bright Solutions, Inc. | Leak detection additives |
US20020096643A1 (en) * | 1996-02-08 | 2002-07-25 | Bright Solutions, Inc., A Michigan Corporation | Portable light source and system for use in leak detection |
US6101867A (en) * | 1998-02-05 | 2000-08-15 | Bright Solutions, Inc. | Dye concentrate |
US6314907B1 (en) | 1999-08-02 | 2001-11-13 | Optiva | Device use indicator |
US6557484B1 (en) * | 2000-10-04 | 2003-05-06 | Jimmy Engelman | Device for sugar and/or caffeine content indication |
DE10164834B4 (de) * | 2001-12-04 | 2004-09-16 | Roche Diagnostics Gmbh | Aufnahme für Proben und Komplettfolie zum Aufnehmen von Proben |
US7319037B1 (en) | 2002-05-14 | 2008-01-15 | Orit Albeck-Marom | Fluid tester and method of use |
US20050272844A1 (en) * | 2004-06-02 | 2005-12-08 | Westman Morton A | Leak detection materials and methods |
US7943380B2 (en) | 2004-06-02 | 2011-05-17 | Bright Solutions, Inc. | Leak detection materials and methods |
US8834946B2 (en) | 2010-12-22 | 2014-09-16 | Drinksavvy, Inc. | System and method for detection of a contaminated beverage |
US20120160725A1 (en) * | 2010-12-22 | 2012-06-28 | Abramson Michael T | System and method for detection of a contaminated beverage |
WO2012087342A1 (en) * | 2010-12-22 | 2012-06-28 | Abramson Michael T | Apparatus for detection of a contaminated beverage and method for producing same |
US8920857B2 (en) | 2010-12-22 | 2014-12-30 | Michael T. Abramson | System and method for detection of a contaminated beverage |
US9285352B2 (en) | 2010-12-22 | 2016-03-15 | Drinksavvy, Inc. | System and method for detection of a contaminated beverage |
US9528973B2 (en) | 2010-12-22 | 2016-12-27 | Drinksavvy, Inc. | System and method for detection of a contaminated beverage |
US9989509B2 (en) | 2010-12-22 | 2018-06-05 | Drinksavvy, Inc. | System and method for detection of a contaminated beverage |
US10254266B2 (en) | 2010-12-22 | 2019-04-09 | Drinksavvy, Inc. | System and method for detection of a contaminated beverage |
US10274475B2 (en) | 2010-12-22 | 2019-04-30 | Drinksavvy, Inc. | System and method for detection of a contaminated beverage |
GB2493763A (en) * | 2011-08-18 | 2013-02-20 | Univ Cranfield | Microplates with Enhanced Immobilisation capabilities |
Also Published As
Publication number | Publication date |
---|---|
FR2185209A5 (enrdf_load_stackoverflow) | 1973-12-28 |
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