US3727602A - Instrument for taking samples from internal organs - Google Patents

Instrument for taking samples from internal organs Download PDF

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Publication number
US3727602A
US3727602A US00110445A US3727602DA US3727602A US 3727602 A US3727602 A US 3727602A US 00110445 A US00110445 A US 00110445A US 3727602D A US3727602D A US 3727602DA US 3727602 A US3727602 A US 3727602A
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body
cannula
plunger
needle
instrument
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Expired - Lifetime
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US00110445A
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V Hyden
S Larsson
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V Hyden
S Larsson
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Priority to SE08251/70A priority Critical patent/SE353016B/xx
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/04Endoscopic instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/0283Pointed or sharp biopsy instruments with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/03Automatic limiting or abutting means, e.g. for safety
    • A61B2090/033Abutting means, stops, e.g. abutting on tissue or skin
    • A61B2090/034Abutting means, stops, e.g. abutting on tissue or skin abutting on parts of the device itself

Abstract

An instrument for taking samples from internal organs of humans and animals in which a cannula for insertion into the organ is detachably connected to a handle portion provided with a plunger pump for drawing the sample into the cannula and a needle of homogeneous material is secured in the pump plunger for axial movement within the cannula and serves to prevent undesired fragments of connective tissues entering the cannula when the cannula passes through the tissues surrounding the internal organ being sampled.

Description

United States Patent [191 Hyden et a1.

[ INSTRUMENT FOR TAKING SAMPLES FROM INTERNAL ORGANS Inventors: Victor Holger Hyden; Sune Torsten Larsson, both of Goteborg, Sweden Assignee: said Hyden and Victor, by said Larsson Romeo 128/304 1 Apr. 17, 1973 l 3,088,454 5/1963 Shute ..128/2 B 2,522,108 9/1950 Flagg ....l28/2 B 1,867,624 7/1932 Hoffman ..l28/2 B 3,040,744 6/ 1962 HOg gard 128/218 C FOREIGN PATENTS OR APPLICATIONS 193,900 3/1923 Great Britain... ..128/347 459,483 5/1928 Germany ...l28/347 587,586 1/1959 Italy ....128/2 13 187,228 4/1967 U.S.S.R ..128/2 B Primary Examiner-l yle L. Howell Attorney-Holman & Stern [5 7 ABSTRACT An instrument for taking samples from internal organs of humans and animals in which a cannula for insertion into the organ is detachably connected to a handle portion provided with a plunger pump for drawing the sample into the cannula and a needle of homogeneous material is secured in the pump plunger for axial movement within the cannula and serves to prevent undesired fragments of connective tissues entering the cannula when the cannula passes through the tissues surrounding the internal organ being sampled.

3 Claims, 5 Drawing Figures 1 INSTRUMENT FOR TAIKHNG SAMPLES FROM INTERNAL ORGANS BACKGROUND OF THE INVENTION PRIOR TECHNIQUES 'A pathologic change of cells in an internal organ, for example the liver, requires an early and safe diagnosis for allowing the curing of the condition by simple means. Sucn pathologic changes heretofore have been diagnosed by an indirect method, viz. by examining the body liquids secreted from the organ in question. This indirect method, however, did not allow for a sufficiently early diagnosis which was its greatest disadvantage. When using a direct method by taking a small tissue sample from the organ, the diagnosis can be made at a very early stage. For this reason, the direct method was introduced for trial purposes. Due to the absence of an instrument of greater suitability, a usual hypodermic syringe. was used and which was provided with a relatively large cannula having an outside diameter of about 2 mm and a conventionally ground clown point into which a tissue sample was sucked. The tissue samples thus taken are to a high degree mixed with connective tissues from the tissues surrounding the internal organ in question. For this reason, introduction was made of the method of placing into the cannula a needle of a homogenous material, and removing the needle after the cannula had penetrated through the tissues in front of the organ into the organ. The quality of the sample thus taken was improved, but the sampling technique showed, certain disadvantages restricting its application. The large cannula, as a matter of fact, in many cases gave rise to complications in the form of bleedings and infections and was somewhat painful for the patient.

A device for taking samples from internal organs which was developed at a later date utilizes a capillary cannula with an outer diameter of 0.3 0.4 mm, the point of which is cutoff perpendicularly and ground to a cone angle of 40 50 to form a circular edge. With this device, the inconvenience and the risk of complications are at a minimum, and the sample taken, when correctly applying the sampling technique, is substantially free of undesirable connective tissue fragments. The device, however, is not entirely satisfactory since it involves obtaining an accurately adjusted vacuum of about 150 mm water-column for sucking the sample into the cannula. A further objection is that this vacuum has to be connected to a separate pump or suc tion hose, which has made it relatively difficult to handle thedevice in practical use.

SUMMARY OF THE INVENTION the sampling technique is improved and simplified. By securing the needle in the plunger, it draws itself automatically back out of the cannula when the sample is being sucked in, and the sample cannot, by the strong vacuum, be sucked up through the cannula to the pump. The cannula preferably is so designed in accordance with the above mentioned prior art device that the advantages of a capillary canuia with its special grinding of the point can be utilized. The outer diameter possibly is to be increased to about 0.5 mm, for preventing the needle from being so thin that it would be uncomfortable to insert the needle into the cannula when the instrument is to be cleaned and sterilized. This increase in diameter by some tenth of a millimeter is so insignificant that it does not imply any disadvantages. The needle diameter is so adjusted in relation to the inner diameter of the cannula that the play therebetween allows the pump to effect sucking through the gap formed, but prevents the tissue sample sucked in to pass the needle. The length of the needle is so adjusted that its free end terminates immediately outside of the cannula mouth when the plunger is in its end position closest to the cannula. When a desired sample quantity has been sucked into the cannula, a pressure balance takes place which interrupts the sucking operation, due to the fact that the plunger on its way exposes a connection to the outer air. The plunger is actuated by a sliding portion on the front part of the handle. The sliding portion is mounted on a cover plate covering a gap, in which a spring clip runs which is secured on the lower surface of the cover plate. The spring clip embraces the plunger in a groove and acts as a carrier. The gap in the pump tube limits the pump stroke. The outer cross-section of the handle can be given a round shape or, which is more advantageous, an angular shape with slightly rounded corners, or it may be given another suitable shape providing a comfortable and safe grip for the hand holding the instrument in the manner of a thick pencil.

In order to avoid the risk of transferring to the patient, for example, infectious yellow jaundice by an unsatisfactorily sterilized cannula, use is made increasingly of throw-away instruments, for example hypodermic syringes, packed in sterile packages and discarded after use. These instruments are assembled of a few simple plastic parts, and as only the cannula is of metal, these instruments are quite inexpensive. The principle can be applied alternatively to an instrument according to the invention. The instrument in such case can be manufactured to be of the throw-away type in its entirety, or it may be sufficient to manufacture only those instrument parts for discard which are to be inserted into the body tissues, i.e. the cannula and the needle. The invention is designed so asto allow for a rapid and simple mounting and dismounting of the cannula and needle.

A preferred embodiment of the instrument is described in greater detail in the following, with reference to the accompanying drawing. i

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a view of longitudinal section through the instrument, with the plunger being in its forward position, I

, FIG. 2 is a view taken along-the line 11-11 in FIG. 1, the view looking in the direction of the arrows,

' with the needle controlled by the plunger, in which FIG. 3 shows the needle position when the plunger is fully inserted, and

FIG. 4 the needle position when the plunger is fully retracted, and

FIG. 5 is a fragmentary view illustrating the manner in which the needle is secured in the plunger.

DETAILED DESCRIPTION F T INVENTION The instrument shown in FIG. 1 comprises a tubular body defining an elongated pump tube ll having a hexagonal outer cross-section with slightly rounded corners, FIG. 2, so as to provide a safe and comfortable grip for the hand. The grip is improved in that the forward portion of the pump tube 1 is knurled. In the forward portion of the pump tube 1 is movably arranged a long plunger 2 provided with a sealing ring 4 mounted in a groove 3 in the plunger. The plunger 2 is actuated by a finger portion 5 on a cover plate s which is connected with the plunger 2 by a spring clip 7 embracing a groove 19 in the plunger 2. A slot 8 for the spring clip 7 is provided in the pump tube l and limits the length of the pump stroke. An aperture 9 in the pump tube ll connects the interior of the pump tube l with the outer air and brings about a pressure balance immediately prior to the arrival of the plunger 2 at its retracted end position, when the aperture 9 is exposed after a suffi ciently great tissue sample has been sucked into the instrument. The rearward portion of the pump tube l is closed by a-rounded plug ill), and the forward portion of tube 1 is designed as a reduced end piece llll having an axial through bore and a gasket l2. On the forward portion of the end piece 11, a quick-coupling 13 of a bayonet type serves to detachably connect a capillary sampling cannula 14 to the end piece. The cannula Rd has a pointed end 15, FIGS., 3 and i which preferably is ground conical to form a sharp circular edge, but it also may have another suitable form (not shown). in the plunger 2, a needle 16 of a homogeneous material is fastened and the needle extendsthrough the axial bore in the end piece 11 and the cannula 11d and terminates in a point 17. The point 1'7 extends immediately outside of the pointed end 15 of the cannula 14 when the plunger 2 isin its inner end position (MG. 3). The diameter of the needle 16 is so adjusted in relation to the inner diameter of the cannula id as to form a narrow gap 18 therebetween, which, during the pumping operation,v allows for a pressure balance between the cannula 14 and the interior of the pump tube ll, but which is sufficiently narrow to prevent the tissue sample taken from passing past the point E7 of the needle (FIG. 4).

For enabling a rapid exchanger or replacement, the needle 16 is mounted detachably in the plunger 2, and more specifically, the plunger 2 is provided with an axial cylindrical hole 20, the forward portion or mouth of which is widened to provide a conical guide 21 for a twice-folded resilient holder 22 of the needle 16. Upon mounting the needle 16, the resilient holder 22 is moved in the direction of the arrow against the plunger 2 with the insertion into the hole ill) being facilitated by the guide 21. The needle 16 having reached the bottom of the hole 20, is resiliently secured in the plunger 2. The force of resilience is sufficient for the needle to to participate in the movements of the plunger 2, but the force is such that the needle easily can be withdrawn from the hole Jill for exchange purposes. The length of the needle T16 is so adjusted that it projects after mounting, some distance outside of the pointed end i5 of the cannula lid. This piece is cut old to align with the pointed end 115.

Before sampling, it is desirable to make certain that the joints between the end piece Ill and the quickcoupling l3 and between the quick-coupling l3 and the cannula l t respectivelyare tight. This can be simply effected by sucking up into the instrument, a liquid innocuous to the body tissues, for example a sterile isotonic saline solution which thereafter is sprayed out of the instrument. The liquid residue remaining in the gap 18 and in cavities behind the gap does not disturb the sampling, but acts as an additional barrier, not necessary per so, when thee instrument passes through the tissue in front of the organ in question.

The instrument is then held similar to a pencil with one finger on the sliding portion 5, which is held in its forward position while the cannula 14 is inserted through the tissue surrounding the organ until the pointed end l5 reaches the sampling area in the internal organ. The plunger 2 is slowly retracted by means of the sliding portion 5 at the same time as the cannula M is inserted an additional short distance whereby a tissue sample is sucked into the forward portion of the cannula id in front of the returning needle 16. When the plunger 2 exposes the aperture 9, the vacuum in the instrument is balanced, and the suction of the tissue sample is completed. The instrument can now carefully be pulled. out while the plunger 2 still is in its retracted position. The sample then removed from the cannula id for examination by moving the plunger 2 to its forward position.

The design of the individual parts as well as the choice of the construction material can be varied to a substantial degree without departing from the basic idea of the invention. it can be imagined, for example, to manufacture the instrument of metal and/or glass, with a constructional design which is suitable in such a case, not the-least in consideration of a repeated use of the instrument, or the instrument can be given a highly simplified design, with most of the details made of plastic, when the instrument is intended to be discarded after use. i

We claim:

1. An instrument for taking tissue samples from internal organs of humans and animals comprising a tubular body having an open end and a closed end, a plunger mounted for axial movement within the body, said body and plunger constituting a vaccum pump, with said body also serving as a handle for the instrument, a cannula constituting a sampling portion of the instrument, said cannula having an outer diameter of about 0.4 min, means detachahly connecting the cannula to the open end of the body, a needle of homogeneous material, means resiliently supporting the needle in the plunger, said needle extending through the open end of the body into the cannula and terminating in a point located immediately outside the end of the cannula when the plunger is at the end of its strolte towards the open end of the body, the outer diameter of the needle and the inner diameter of the cannula being such as to provide a narrow annular gap between the needle and cannula, said gap allowing for a pressure balance between the cannula and the body upon movement of the plunger from the open end toward the closed end of the body yet preventing the passage of the tissue sample past the point of the needle during the movement of the needle with thee plunger, said body having an axial slot therein, means attached to the plunger and projecting through said axial slot, a member slidably mounted on the outside of said body to which said attaching means is secured, the length of the axial slot limiting the stroke of the plunger, and said body having an aperture in proximity to the open end of the body to provide communication between the body and the outer air, said aperture being closed when the plunger is adjacent the open end of the body but being exposed when the plunger moves toward the end of its stroke in the direction of the closed end of the body after a tissue sample has been drawn into the cannula to effect the pressure balance.

2. The instrument according to claim 1, characterized in that said attaching means is a spring clip and said slidably mounted member is a cover plate.

3. The instrument according to claim 1, characterized in that the resilient supporting means for the needle comprises a twice-folded resilient holder and an axial cylindrical hole in the plunger having a widened mouth to form a conical guide into which the holder may be inserted and removed.

Claims (3)

1. An instrument for taking tissue samples from internal organs of humans and animals comprising a tubular body having an open end and a closed end, a plunger mounted for axial movement within the body, said body and plunger constituting a vacuum pump, with said body also serving as a handle for the instrument, a cannula constituting a sampling portion of the instrument, said cannula having an outer diameter of about 0.4 mm, means detachably connecting the cannula to the open end of the body, a needle of homogeneous material, means resiliently supporting the needle in the plunger, said needle extending through the open end of the body into the cannula and terminating in a point located immediately outside the end of the cannula when the plunger is at the end of its stroke towards the open end of the body, the outer diameter of the needle and the inner diameter of the cannula being such as to provide a narrow annular gap between the needle and cannula, said gap allowing for a pressure balance between the cannula and the body upon movement of the plunger from the open end toward the closed end of the body yet preventing the passage of the tissue sample past the point of the needle during the movement of the needle with thee plunger, said body having an axial slot therein, means attached to the plunger and projecting through said axial slot, a member slidably mounted on the outside of said body to which said attaching means is secured, the length of the axial slot limiting the stroke of the plunger, and said body having an aperture in proximity to the open end of the body to provide communication between the body and the outer air, said aperture being closed when the plunger is adjacent the open end of the body but being exposed when the plunger moves toward the end of its stroke in the direction of the closed end of the body after a tissue sample has been drawn into the cannula to effect the pressure balance.
2. The instrument according to claim 1, characterized in that said attaching means is a spring clip and said slidably mounted member is a cover plate.
3. The instrument according to claim 1, characterized in that the resilient supporting means for the needle comprises a twice-folded resilient holder and an axial cylindrical hole in the plunger having a widened mouth to form a conical guide into which the holder may be inserted and removed.
US00110445A 1970-06-15 1971-01-28 Instrument for taking samples from internal organs Expired - Lifetime US3727602A (en)

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AT (1) AT308278B (en)
CA (1) CA927702A (en)
CH (1) CH524995A (en)
DE (1) DE2043843C3 (en)
ES (1) ES383777A1 (en)
FR (1) FR2095435A5 (en)
GB (1) GB1283309A (en)
IE (1) IE34640B1 (en)
SE (1) SE353016B (en)

Cited By (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3882849A (en) * 1974-03-25 1975-05-13 Khosrow Jamshidi Soft Tissue Biopsy Device
US3938505A (en) * 1974-08-16 1976-02-17 Khosrow Jamshidi Soft tissue biopsy aspirating device
US4230128A (en) * 1978-03-30 1980-10-28 Aramayo Rene S Catheter attachment for blood sampling
US4396022A (en) * 1980-07-22 1983-08-02 Marx Alvin J Endometrial tissue sampling apparatus
US4532935A (en) * 1982-11-01 1985-08-06 Wang Ko P Bronchoscopic needle assembly
EP0186256A1 (en) * 1984-10-24 1986-07-02 Hakko Electric Machine Works Co. Ltd. Biopsy needle set
US4766906A (en) * 1981-05-06 1988-08-30 Ko Pen Wang Bronchoscopic needle assembly
US4785826A (en) * 1987-03-02 1988-11-22 Ward John L Biopsy instrument
US5116323A (en) * 1991-01-22 1992-05-26 Becton, Dickinson And Company Arterial catheter
US5197485A (en) * 1991-10-15 1993-03-30 Pilling Co. Method and apparatus for sampling aortic plaque
US5246011A (en) * 1992-01-30 1993-09-21 Caillouette James C Fine needle aspiration syringe
US5255688A (en) * 1989-09-27 1993-10-26 Bredam Medical Distribution S.A. Instrument for handling biopsies and specimens
US5423330A (en) * 1993-03-10 1995-06-13 The University Of Miami Capsule suction punch instrument and method of use
US5651372A (en) * 1995-06-28 1997-07-29 Caillouette; James C. Biopsy syringe
US20050165328A1 (en) * 2002-03-19 2005-07-28 Norbert Heske Biopsy device and biopsy needle module that can be inserted into the biopsy device
US20050203439A1 (en) * 2002-03-19 2005-09-15 Norbert Heske Vacuum biopsy device
WO2006005343A1 (en) * 2004-07-09 2006-01-19 Sonion Roskilde A/S Length detection system for biopsy device
US20080306406A1 (en) * 2005-08-10 2008-12-11 C.R. Bard Inc. Single-Insertion, Multiple Sampling Biopsy Device With Linear Drive
US20080319341A1 (en) * 2005-08-10 2008-12-25 C.R. Bard Inc. Single-Insertion, Multiple Sample Biopsy Device with Integrated Markers
US20090227893A1 (en) * 2005-08-10 2009-09-10 C.R. Bard Inc. Single-insertion, multiple sampling biopsy device usable with various transport systems and integrated markers
US20100030108A1 (en) * 2006-10-24 2010-02-04 C.R. Bard, Inc. Large sample low aspect ratio biopsy needle
US20100106053A1 (en) * 2006-10-06 2010-04-29 Videbaek Karsten Tissue handling system with reduced operator exposure
US20100234760A1 (en) * 2006-08-21 2010-09-16 Dan Almazan Self-contained Handheld Biopsy Needle
US20110021946A1 (en) * 2003-03-29 2011-01-27 C.R. Bard, Inc. Biopsy needle system having a pressure generating unit
US20110054349A1 (en) * 2007-12-27 2011-03-03 Devicor Medical Products, Inc. Clutch and valving system for tetherless biopsy device
US20110054350A1 (en) * 2009-09-01 2011-03-03 Videbaek Karsten Biopsy apparatus having a tissue sample retrieval mechanism
US20110077551A1 (en) * 2009-09-25 2011-03-31 Videbaek Karsten Charging station for battery powered biopsy apparatus
US20110087131A1 (en) * 2009-10-12 2011-04-14 Videbaek Karsten Biopsy probe assembly having a mechanism to prevent misalignment of components prior to installation
EP1915949A3 (en) * 2004-07-09 2011-04-20 Bard Peripheral Vascular, Inc. Biopsy device
US20110105946A1 (en) * 2009-10-31 2011-05-05 Sorensen Peter L Biopsy system with infrared communications
US20110105945A1 (en) * 2009-10-29 2011-05-05 Videbaek Karsten Biopsy driver assembly having a control circuit for conserving battery power
US20110208085A1 (en) * 2005-01-31 2011-08-25 C.R. Bard, Inc. Quick cycle biopsy system
US8597205B2 (en) 2007-12-20 2013-12-03 C. R. Bard, Inc. Biopsy device
US8690793B2 (en) 2009-03-16 2014-04-08 C. R. Bard, Inc. Biopsy device having rotational cutting
US8708929B2 (en) 2009-04-15 2014-04-29 Bard Peripheral Vascular, Inc. Biopsy apparatus having integrated fluid management
US8845548B2 (en) 2009-06-12 2014-09-30 Devicor Medical Products, Inc. Cutter drive assembly for biopsy device
US9173641B2 (en) 2009-08-12 2015-11-03 C. R. Bard, Inc. Biopsy apparatus having integrated thumbwheel mechanism for manual rotation of biopsy cannula
US10285673B2 (en) 2013-03-20 2019-05-14 Bard Peripheral Vascular, Inc. Biopsy device

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6048601U (en) * 1983-09-09 1985-04-05
US4784156A (en) * 1987-09-16 1988-11-15 Garg Rakesh K Cannula including a valve structure and associated instrument elements and method for using same

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU187228A1 (en) * Tool for punking biopsy of internal organs
US1080929A (en) * 1912-08-16 1913-12-09 Surgical Supply Imp Ing Company Curette.
GB193900A (en) * 1921-10-06 1923-03-06 Hubert Oliver Gunewardene An aspirator for safely removing fluid from any serous sac
DE459483C (en) * 1928-05-07 Ehrhard Henke A device for withdrawal of blood samples from the human or animal body
US1867624A (en) * 1930-04-01 1932-07-19 Memorial Hospital For The Trea Device for obtaining biopsy specimens
US2522108A (en) * 1948-09-07 1950-09-12 Memorial Hospital Aspiration biopsy
US3040744A (en) * 1960-06-17 1962-06-26 Kenneth A Hoggard Syringe plunger ejector
US3088454A (en) * 1960-01-06 1963-05-07 Wallace B Shute Surgical instrument
US3330268A (en) * 1963-12-18 1967-07-11 Goldsmith Sidney Biopsy needle
US3470867A (en) * 1964-11-23 1969-10-07 Sidney Goldsmith Biopsy needle

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU187228A1 (en) * Tool for punking biopsy of internal organs
DE459483C (en) * 1928-05-07 Ehrhard Henke A device for withdrawal of blood samples from the human or animal body
US1080929A (en) * 1912-08-16 1913-12-09 Surgical Supply Imp Ing Company Curette.
GB193900A (en) * 1921-10-06 1923-03-06 Hubert Oliver Gunewardene An aspirator for safely removing fluid from any serous sac
US1867624A (en) * 1930-04-01 1932-07-19 Memorial Hospital For The Trea Device for obtaining biopsy specimens
US2522108A (en) * 1948-09-07 1950-09-12 Memorial Hospital Aspiration biopsy
US3088454A (en) * 1960-01-06 1963-05-07 Wallace B Shute Surgical instrument
US3040744A (en) * 1960-06-17 1962-06-26 Kenneth A Hoggard Syringe plunger ejector
US3330268A (en) * 1963-12-18 1967-07-11 Goldsmith Sidney Biopsy needle
US3470867A (en) * 1964-11-23 1969-10-07 Sidney Goldsmith Biopsy needle

Cited By (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3882849A (en) * 1974-03-25 1975-05-13 Khosrow Jamshidi Soft Tissue Biopsy Device
US3938505A (en) * 1974-08-16 1976-02-17 Khosrow Jamshidi Soft tissue biopsy aspirating device
US4230128A (en) * 1978-03-30 1980-10-28 Aramayo Rene S Catheter attachment for blood sampling
US4396022A (en) * 1980-07-22 1983-08-02 Marx Alvin J Endometrial tissue sampling apparatus
US4766906A (en) * 1981-05-06 1988-08-30 Ko Pen Wang Bronchoscopic needle assembly
US4532935A (en) * 1982-11-01 1985-08-06 Wang Ko P Bronchoscopic needle assembly
EP0186256A1 (en) * 1984-10-24 1986-07-02 Hakko Electric Machine Works Co. Ltd. Biopsy needle set
US4785826A (en) * 1987-03-02 1988-11-22 Ward John L Biopsy instrument
US5255688A (en) * 1989-09-27 1993-10-26 Bredam Medical Distribution S.A. Instrument for handling biopsies and specimens
US5116323A (en) * 1991-01-22 1992-05-26 Becton, Dickinson And Company Arterial catheter
US5197485A (en) * 1991-10-15 1993-03-30 Pilling Co. Method and apparatus for sampling aortic plaque
US5246011A (en) * 1992-01-30 1993-09-21 Caillouette James C Fine needle aspiration syringe
US5423330A (en) * 1993-03-10 1995-06-13 The University Of Miami Capsule suction punch instrument and method of use
US5651372A (en) * 1995-06-28 1997-07-29 Caillouette; James C. Biopsy syringe
US9421002B2 (en) 2002-03-19 2016-08-23 C. R. Bard, Inc. Disposable biopsy unit
US20050203439A1 (en) * 2002-03-19 2005-09-15 Norbert Heske Vacuum biopsy device
US8109885B2 (en) 2002-03-19 2012-02-07 C. R. Bard, Inc. Biopsy device for removing tissue specimens using a vacuum
US20070149894A1 (en) * 2002-03-19 2007-06-28 C.R. Bard, Inc. Biopsy device for removing tissue specimens using a vacuum
US8951209B2 (en) 2002-03-19 2015-02-10 C. R. Bard, Inc. Biopsy device and insertable biopsy needle module
US8052614B2 (en) 2002-03-19 2011-11-08 C. R. Bard, Inc. Biopsy device having a vacuum pump
US8016772B2 (en) 2002-03-19 2011-09-13 C. R. Bard, Inc. Biopsy device for removing tissue specimens using a vacuum
US20050165328A1 (en) * 2002-03-19 2005-07-28 Norbert Heske Biopsy device and biopsy needle module that can be inserted into the biopsy device
US9072502B2 (en) 2002-03-19 2015-07-07 C. R. Bard, Inc. Disposable biopsy unit
US8172773B2 (en) 2002-03-19 2012-05-08 C. R. Bard, Inc. Biopsy device and biopsy needle module that can be inserted into the biopsy device
US10335128B2 (en) 2002-03-19 2019-07-02 C. R. Bard, Inc. Biopsy device and insertable biopsy needle module
US10271827B2 (en) 2002-03-19 2019-04-30 C. R. Bard, Inc. Disposable biopsy unit
US20100106055A1 (en) * 2002-03-19 2010-04-29 C.R. Bard, Inc. Biopsy device having a vacuum pump
US8002713B2 (en) 2002-03-19 2011-08-23 C. R. Bard, Inc. Biopsy device and insertable biopsy needle module
US9439631B2 (en) 2002-03-19 2016-09-13 C. R. Bard, Inc. Biopsy device and insertable biopsy needle module
US8162851B2 (en) 2003-03-29 2012-04-24 C. R. Bard, Inc. Biopsy needle system having a pressure generating unit
US8728004B2 (en) 2003-03-29 2014-05-20 C.R. Bard, Inc. Biopsy needle system having a pressure generating unit
US20110021946A1 (en) * 2003-03-29 2011-01-27 C.R. Bard, Inc. Biopsy needle system having a pressure generating unit
US20100210966A1 (en) * 2004-07-09 2010-08-19 Bard Peripheral Vascular, Inc. Firing System For Biopsy Device
US8366636B2 (en) 2004-07-09 2013-02-05 Bard Peripheral Vascular, Inc. Firing system for biopsy device
EP1915949A3 (en) * 2004-07-09 2011-04-20 Bard Peripheral Vascular, Inc. Biopsy device
US9456809B2 (en) 2004-07-09 2016-10-04 Bard Peripheral Vascular, Inc. Tissue sample flushing system for biopsy device
US9872672B2 (en) 2004-07-09 2018-01-23 Bard Peripheral Vascular, Inc. Length detection system for biopsy device
US10166011B2 (en) 2004-07-09 2019-01-01 Bard Peripheral Vascular, Inc. Transport system for biopsy device
US8992440B2 (en) 2004-07-09 2015-03-31 Bard Peripheral Vascular, Inc. Length detection system for biopsy device
US8926527B2 (en) 2004-07-09 2015-01-06 Bard Peripheral Vascular, Inc. Tissue sample flushing system for biopsy device
US8864680B2 (en) 2004-07-09 2014-10-21 Bard Peripheral Vascular, Inc. Transport system for biopsy device
US20080287826A1 (en) * 2004-07-09 2008-11-20 Bard Peripheral Vasular, Inc. Transport System for Biopsy Device
US20080183099A1 (en) * 2004-07-09 2008-07-31 Martin Bondo Jorgensen Tissue Sample Flushing System for Biopsy Device
US8052615B2 (en) 2004-07-09 2011-11-08 Bard Peripheral Vascular, Inc. Length detection system for biopsy device
US9345458B2 (en) 2004-07-09 2016-05-24 Bard Peripheral Vascular, Inc. Transport system for biopsy device
US8157744B2 (en) 2004-07-09 2012-04-17 Bard Peripheral Vascular, Inc. Tissue sample flushing system for biopsy device
US20080071193A1 (en) * 2004-07-09 2008-03-20 Claus Reuber Length Detection System for Biopsy Device
WO2006005343A1 (en) * 2004-07-09 2006-01-19 Sonion Roskilde A/S Length detection system for biopsy device
US10058308B2 (en) 2005-01-31 2018-08-28 C. R. Bard, Inc. Method for operating a biopsy apparatus
US8702621B2 (en) 2005-01-31 2014-04-22 C.R. Bard, Inc. Quick cycle biopsy system
US9161743B2 (en) 2005-01-31 2015-10-20 C. R. Bard, Inc. Quick cycle biopsy system
US8702622B2 (en) 2005-01-31 2014-04-22 C.R. Bard, Inc. Quick cycle biopsy system
US8012102B2 (en) 2005-01-31 2011-09-06 C. R. Bard, Inc. Quick cycle biopsy system
US20110208085A1 (en) * 2005-01-31 2011-08-25 C.R. Bard, Inc. Quick cycle biopsy system
US8728003B2 (en) 2005-08-10 2014-05-20 C.R. Bard Inc. Single insertion, multiple sample biopsy device with integrated markers
US10010307B2 (en) 2005-08-10 2018-07-03 C. R. Bard, Inc. Single-insertion, multiple sampling biopsy device with linear drive
US10368849B2 (en) 2005-08-10 2019-08-06 C. R. Bard, Inc. Single-insertion, multiple sampling biopsy device usable with various transport systems and integrated markers
US20090227893A1 (en) * 2005-08-10 2009-09-10 C.R. Bard Inc. Single-insertion, multiple sampling biopsy device usable with various transport systems and integrated markers
US20080319341A1 (en) * 2005-08-10 2008-12-25 C.R. Bard Inc. Single-Insertion, Multiple Sample Biopsy Device with Integrated Markers
US20080306406A1 (en) * 2005-08-10 2008-12-11 C.R. Bard Inc. Single-Insertion, Multiple Sampling Biopsy Device With Linear Drive
US8771200B2 (en) 2005-08-10 2014-07-08 C.R. Bard, Inc. Single insertion, multiple sampling biopsy device with linear drive
US8721563B2 (en) 2005-08-10 2014-05-13 C. R. Bard, Inc. Single-insertion, multiple sample biopsy device with integrated markers
US8267868B2 (en) 2005-08-10 2012-09-18 C. R. Bard, Inc. Single-insertion, multiple sample biopsy device with integrated markers
US8262585B2 (en) 2005-08-10 2012-09-11 C. R. Bard, Inc. Single-insertion, multiple sampling biopsy device with linear drive
US8961430B2 (en) 2005-08-10 2015-02-24 C.R. Bard, Inc. Single-insertion, multiple sampling biopsy device usable with various transport systems and integrated markers
US8282574B2 (en) 2005-08-10 2012-10-09 C. R. Bard, Inc. Single-insertion, multiple sampling biopsy device usable with various transport systems and integrated markers
US8251917B2 (en) 2006-08-21 2012-08-28 C. R. Bard, Inc. Self-contained handheld biopsy needle
US20100234760A1 (en) * 2006-08-21 2010-09-16 Dan Almazan Self-contained Handheld Biopsy Needle
US9439632B2 (en) 2006-08-21 2016-09-13 C. R. Bard, Inc. Self-contained handheld biopsy needle
US8951208B2 (en) 2006-08-21 2015-02-10 C. R. Bard, Inc. Self-contained handheld biopsy needle
US8485987B2 (en) 2006-10-06 2013-07-16 Bard Peripheral Vascular, Inc. Tissue handling system with reduced operator exposure
US20100106053A1 (en) * 2006-10-06 2010-04-29 Videbaek Karsten Tissue handling system with reduced operator exposure
US10172594B2 (en) 2006-10-06 2019-01-08 Bard Peripheral Vascular, Inc. Tissue handling system with reduced operator exposure
US9566045B2 (en) 2006-10-06 2017-02-14 Bard Peripheral Vascular, Inc. Tissue handling system with reduced operator exposure
US10149664B2 (en) 2006-10-24 2018-12-11 C. R. Bard, Inc. Large sample low aspect ratio biopsy needle
US8262586B2 (en) 2006-10-24 2012-09-11 C. R. Bard, Inc. Large sample low aspect ratio biopsy needle
US20100030108A1 (en) * 2006-10-24 2010-02-04 C.R. Bard, Inc. Large sample low aspect ratio biopsy needle
US8858463B2 (en) 2007-12-20 2014-10-14 C. R. Bard, Inc. Biopsy device
US9775588B2 (en) 2007-12-20 2017-10-03 C. R. Bard, Inc. Biopsy device
US8597205B2 (en) 2007-12-20 2013-12-03 C. R. Bard, Inc. Biopsy device
US8454532B2 (en) 2007-12-27 2013-06-04 Devicor Medical Products, Inc. Clutch and valving system for tetherless biopsy device
US20110054349A1 (en) * 2007-12-27 2011-03-03 Devicor Medical Products, Inc. Clutch and valving system for tetherless biopsy device
US8864682B2 (en) 2007-12-27 2014-10-21 Devicor Medical Products, Inc. Clutch and valving system for tetherless biopsy device
US8690793B2 (en) 2009-03-16 2014-04-08 C. R. Bard, Inc. Biopsy device having rotational cutting
US8708930B2 (en) 2009-04-15 2014-04-29 Bard Peripheral Vascular, Inc. Biopsy apparatus having integrated fluid management
US8708929B2 (en) 2009-04-15 2014-04-29 Bard Peripheral Vascular, Inc. Biopsy apparatus having integrated fluid management
US8708928B2 (en) 2009-04-15 2014-04-29 Bard Peripheral Vascular, Inc. Biopsy apparatus having integrated fluid management
US8845548B2 (en) 2009-06-12 2014-09-30 Devicor Medical Products, Inc. Cutter drive assembly for biopsy device
US9468424B2 (en) 2009-06-12 2016-10-18 Devicor Medical Products, Inc. Cutter drive assembly for biopsy device
US9173641B2 (en) 2009-08-12 2015-11-03 C. R. Bard, Inc. Biopsy apparatus having integrated thumbwheel mechanism for manual rotation of biopsy cannula
US9655599B2 (en) 2009-08-12 2017-05-23 C. R. Bard, Inc. Biopsy apparatus having integrated thumbwheel mechanism for manual rotation of biopsy cannula
US9282949B2 (en) 2009-09-01 2016-03-15 Bard Peripheral Vascular, Inc. Charging station for battery powered biopsy apparatus
US8485989B2 (en) 2009-09-01 2013-07-16 Bard Peripheral Vascular, Inc. Biopsy apparatus having a tissue sample retrieval mechanism
US9949726B2 (en) 2009-09-01 2018-04-24 Bard Peripheral Vscular, Inc. Biopsy driver assembly having a control circuit for conserving battery power
US20110054350A1 (en) * 2009-09-01 2011-03-03 Videbaek Karsten Biopsy apparatus having a tissue sample retrieval mechanism
US8283890B2 (en) 2009-09-25 2012-10-09 Bard Peripheral Vascular, Inc. Charging station for battery powered biopsy apparatus
US20110077551A1 (en) * 2009-09-25 2011-03-31 Videbaek Karsten Charging station for battery powered biopsy apparatus
USD640977S1 (en) 2009-09-25 2011-07-05 C. R. Bard, Inc. Charging station for a battery operated biopsy device
US20110087131A1 (en) * 2009-10-12 2011-04-14 Videbaek Karsten Biopsy probe assembly having a mechanism to prevent misalignment of components prior to installation
US8597206B2 (en) 2009-10-12 2013-12-03 Bard Peripheral Vascular, Inc. Biopsy probe assembly having a mechanism to prevent misalignment of components prior to installation
US8430824B2 (en) 2009-10-29 2013-04-30 Bard Peripheral Vascular, Inc. Biopsy driver assembly having a control circuit for conserving battery power
US8808197B2 (en) 2009-10-29 2014-08-19 Bard Peripheral Vascular, Inc. Biopsy driver assembly having a control circuit for conserving battery power
US20110105945A1 (en) * 2009-10-29 2011-05-05 Videbaek Karsten Biopsy driver assembly having a control circuit for conserving battery power
US20110105946A1 (en) * 2009-10-31 2011-05-05 Sorensen Peter L Biopsy system with infrared communications
US10285673B2 (en) 2013-03-20 2019-05-14 Bard Peripheral Vascular, Inc. Biopsy device

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ES383777A1 (en) 1973-03-01
CA927702A1 (en)
DE2043843C3 (en) 1973-10-31
DE2043843B2 (en) 1973-04-05
JPS4925037B1 (en) 1974-06-27
IE34640L (en) 1971-12-15
IE34640B1 (en) 1975-07-09
DE2043843A1 (en) 1972-01-27
FR2095435A5 (en) 1972-02-11
GB1283309A (en) 1972-07-26
CA927702A (en) 1973-06-05
SE353016B (en) 1973-01-22
AT308278B (en) 1973-06-25
CH524995A (en) 1972-07-15

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