US3714035A - Method and apparatus for thin layer chromatography - Google Patents

Method and apparatus for thin layer chromatography Download PDF

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Publication number
US3714035A
US3714035A US00146577A US3714035DA US3714035A US 3714035 A US3714035 A US 3714035A US 00146577 A US00146577 A US 00146577A US 3714035D A US3714035D A US 3714035DA US 3714035 A US3714035 A US 3714035A
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United States
Prior art keywords
thin layer
unknown
chromatograph
insert
compounds
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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US00146577A
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English (en)
Inventor
D Jones
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ANALYTICAL SYSTEMS Inc A CORP OF
TOXI-LAB Inc A CORP OF CA
Marion Laboratories Inc
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Individual
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Assigned to ANALYTICAL SYSTEMS, INC., A CORP. OF CA reassignment ANALYTICAL SYSTEMS, INC., A CORP. OF CA ASSIGNMENT OF ASSIGNORS INTEREST. Assignors: JONES, DONALD W.
Assigned to MARION LABORATORIES, INC., A CORP. OF DE reassignment MARION LABORATORIES, INC., A CORP. OF DE ASSIGNMENT OF ASSIGNORS INTEREST. Assignors: JONES, DONALD W., M.D., JONES, JULIE E.
Assigned to TOXI-LAB, INC., A CORP. OF CA. reassignment TOXI-LAB, INC., A CORP. OF CA. ASSIGNMENT OF ASSIGNORS INTEREST. Assignors: MARION LABORATORIES, INC.,
Assigned to SECURITY PACIFIC NATIONAL BANK, A NATIONAL BANKING ASSOCIATION reassignment SECURITY PACIFIC NATIONAL BANK, A NATIONAL BANKING ASSOCIATION SECURITY INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: TOXI-LAB, INC., A CORP. OF CA
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Expired - Lifetime legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/90—Plate chromatography, e.g. thin layer or paper chromatography
    • G01N30/91—Application of the sample

Definitions

  • an unknown sample is obtained, either from such biological fluid as urine, saliva, blood, or other fluid, and treated in an appropriate manner, so as to permit extraction of a class of compounds.
  • biological fluid such as urine, saliva, blood, or other fluid
  • an appropriate manner so as to permit extraction of a class of compounds.
  • basic compounds such as amines were to be extracted, normally a high pH would be used.
  • acid compound normally a low pH would be used.
  • the subject invention may be used with other than body fluids, such as scrapings from plants, digested plants, pollutants, or any material which has a component which is to be assayed.
  • a thin layer chromatograph having a plurality of scored or hollow areas, the hollow areas obtained by removal of the scored portion;
  • a thin layer chromatograph according to claim 8 wherein the adsorbent of said chromatograph is silica gel or alumina and said adsorbent is supported by glass fiber or foil.

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  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
US00146577A 1971-05-19 1971-05-19 Method and apparatus for thin layer chromatography Expired - Lifetime US3714035A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14657771A 1971-05-19 1971-05-19

Publications (1)

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US3714035A true US3714035A (en) 1973-01-30

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ID=22518025

Family Applications (1)

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US00146577A Expired - Lifetime US3714035A (en) 1971-05-19 1971-05-19 Method and apparatus for thin layer chromatography

Country Status (8)

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US (1) US3714035A (de)
JP (1) JPS5441238B1 (de)
CA (1) CA971112A (de)
CH (1) CH571880A5 (de)
DE (1) DE2224411C3 (de)
FR (1) FR2138020B1 (de)
GB (1) GB1362463A (de)
SE (1) SE390216B (de)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3757952A (en) * 1971-08-31 1973-09-11 Eastman Kodak Co Template for applying samples to a thin layer chromatographic sheet
US3869409A (en) * 1972-06-08 1975-03-04 Natalya Karlovna Bebris Process for preparing a wide-pore adsorbent for use in chromatography
US3963421A (en) * 1974-07-12 1976-06-15 Sierra Laboratories, Inc. TLC method for drug detection
US4272380A (en) * 1979-09-13 1981-06-09 Analytical Systems, Inc. Solvent front detection method and manufacture
US4804469A (en) * 1985-01-25 1989-02-14 Walsh James W Flexible jacket membrane processing apparatus
US5171528A (en) * 1989-10-18 1992-12-15 Wardlaw Stephen C Device for differentiating the source of occult gastro-intestinal bleeding
WO1993001494A1 (en) * 1991-07-12 1993-01-21 Toxi Lab, Inc. Method and apparatus for improved solid phase extraction
WO1993005387A1 (en) * 1989-10-18 1993-03-18 Wardlaw Stephen C Differentiating the source of occult gastrointestinal bleeding
WO1997049988A1 (de) * 1996-06-21 1997-12-31 Kuehn Michael Verfahren und mischung zur herstellung eines selbsttragenden werkstoffs sowie werkstoff

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU184065B (en) * 1979-12-06 1984-06-28 Mueszeripari Muevek Lab Cromatographic layer sheet for a pressurized layer chromatographic equipment

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE7008546U (de) * 1970-03-09 1971-01-14 Syre Kurt Auftrageplatte fuer duennschicht-chromatographie.

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3757952A (en) * 1971-08-31 1973-09-11 Eastman Kodak Co Template for applying samples to a thin layer chromatographic sheet
US3869409A (en) * 1972-06-08 1975-03-04 Natalya Karlovna Bebris Process for preparing a wide-pore adsorbent for use in chromatography
US3963421A (en) * 1974-07-12 1976-06-15 Sierra Laboratories, Inc. TLC method for drug detection
US4272380A (en) * 1979-09-13 1981-06-09 Analytical Systems, Inc. Solvent front detection method and manufacture
US4804469A (en) * 1985-01-25 1989-02-14 Walsh James W Flexible jacket membrane processing apparatus
US5171528A (en) * 1989-10-18 1992-12-15 Wardlaw Stephen C Device for differentiating the source of occult gastro-intestinal bleeding
WO1993005387A1 (en) * 1989-10-18 1993-03-18 Wardlaw Stephen C Differentiating the source of occult gastrointestinal bleeding
WO1993001494A1 (en) * 1991-07-12 1993-01-21 Toxi Lab, Inc. Method and apparatus for improved solid phase extraction
WO1997049988A1 (de) * 1996-06-21 1997-12-31 Kuehn Michael Verfahren und mischung zur herstellung eines selbsttragenden werkstoffs sowie werkstoff

Also Published As

Publication number Publication date
CA971112A (en) 1975-07-15
FR2138020B1 (de) 1973-07-13
DE2224411B2 (de) 1980-09-18
GB1362463A (en) 1974-08-07
SE390216B (sv) 1976-12-06
DE2224411A1 (de) 1972-12-07
FR2138020A1 (de) 1972-12-29
CH571880A5 (de) 1976-01-30
JPS5441238B1 (de) 1979-12-07
DE2224411C3 (de) 1981-11-05

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Legal Events

Date Code Title Description
AS Assignment

Owner name: ANALYTICAL SYSTEMS, INC., 23162 LA CADENA DRIVE, L

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST. EFFECTIVE MAY 19. 1981.;ASSIGNOR:JONES, DONALD W.;REEL/FRAME:003866/0270

Effective date: 19810519

AS Assignment

Owner name: MARION LABORATORIES, INC., A CORP. OF DE, MISSOU

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:JONES, DONALD W., M.D.;JONES, JULIE E.;REEL/FRAME:004983/0846

Effective date: 19881212

Owner name: MARION LABORATORIES, INC., 9300 WARD PARKWAY, KANS

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNORS:JONES, DONALD W., M.D.;JONES, JULIE E.;REEL/FRAME:004983/0846

Effective date: 19881212

AS Assignment

Owner name: TOXI-LAB, INC., A CORP. OF CA., CALIFORNIA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:MARION LABORATORIES, INC.,;REEL/FRAME:004983/0895

Effective date: 19881212

Owner name: TOXI-LAB, INC., 2 GOODYEAR, IRVINE, CA. 92718, A C

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:MARION LABORATORIES, INC.,;REEL/FRAME:004983/0895

Effective date: 19881212

AS Assignment

Owner name: SECURITY PACIFIC NATIONAL BANK, A NATIONAL BANKING

Free format text: SECURITY INTEREST;ASSIGNOR:TOXI-LAB, INC., A CORP. OF CA;REEL/FRAME:004980/0354

Effective date: 19881212

Owner name: SECURITY PACIFIC NATIONAL BANK, 4000 MACARTHUR BOU

Free format text: SECURITY INTEREST;ASSIGNOR:TOXI-LAB, INC., A CORP. OF CA;REEL/FRAME:004980/0354

Effective date: 19881212