US3616265A - Device for making a culture of microorganisms - Google Patents

Device for making a culture of microorganisms Download PDF

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Publication number
US3616265A
US3616265A US848212A US3616265DA US3616265A US 3616265 A US3616265 A US 3616265A US 848212 A US848212 A US 848212A US 3616265D A US3616265D A US 3616265DA US 3616265 A US3616265 A US 3616265A
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Prior art keywords
container
elongated member
culture medium
brush
guide member
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US848212A
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Anthony J Calabrese
Joseph F Pagano
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Smith Kline and French Laboratories Ltd
SmithKline Beecham Corp
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Smith Kline and French Laboratories Ltd
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Assigned to SMITHKLINE BECKMAN CORPORATION reassignment SMITHKLINE BECKMAN CORPORATION CHANGE OF NAME (SEE DOCUMENT FOR DETAILS). EFFECTIVE DATE: 03/04/82 Assignors: SMITHKLINE CORPORATION
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/22—Transparent or translucent parts

Definitions

  • a device for making a culture of micro-organisms has an elongated member which advantageously supports a culture medium on each of two opposite flat faces.
  • a container having an open end is provided for the elongated member.
  • a brush mounted in the container contacts the elongated member intermediate its ends.
  • the open end of the container has removable means to seal it.
  • the elongated member is removed from the container and the end thereof brought into contact with the area of the patient suspected of having micro-organsims.
  • the container has a guide member to guide the elongated member and restrict its movement toward the interior surfaces of the container.
  • the brush forms a part of the guide member and the elongated member has a plug adapted to form a seal with the guide member to permit the withdrawal of the elongated member from the container either independently of the guide member or together with the guide member.
  • PAGANO BM M lllII -IIIlllll !IIIII -IIIIIIIII PATENTEDUCT 2 6 I971 ATTORNEYS DEVICE FOR MAKING A CULTURE OF MICRO- ORGANISMS BACKGROUND OF THE INVENTION
  • Devices for making a culture of microorganisms having a culture medium which can be brought directly into contact with an area of a patients body and then returned to a sealed container for growing micro-organisms picked up are known to the art as is seen, for example, in the disclosure of U.S. Pat. No. 3,368,549, issued Feb. 13, 1968. Such devices have as their intended purpose providing office diagnosis within 24 hours without the necessity for a laboratory.
  • a device for making a culture of micro-organisms has an elongated support member which carries a culture medium supported by said member preferably intermediate the ends thereof.
  • a container having an open end is adapted to contain the elongated member and has a brush mounted therein to brush over the inner end of the elongated member and at least a portion of the culture medium on insertion of the elongated member into the container.
  • the container is transparent and has flat surfaces through which the culture medium is viewed.
  • a seal for the open end of the container is provided and it advantageously forms a part of the elongated member.
  • a hollow guide member guides the elongated member within the container to restrict its movement towards the interior surfaces of the container.
  • the brush forms a part of said guide member and the elongated member has a plug engaging the guide member to seal the container.
  • the guide member is removable.
  • FIG. 1 is an elevational view of a prior art device
  • FIG. 2 is an elevational view of a device in accordance with the invention.
  • FIG. 3 is a vertical section taken on the plane indicated by the line 3-3 in FIG. 2;
  • FIG. 4 is an end of view of the guide member and brush of the device of FIG. 2;
  • FIG. 5 is a side elevation of the structure of FIG. 4;
  • FIG. 6 is a top plan view of the elongated support member of the device of FIG. 2 without the culture medium;
  • FIG. 7 is a top plan view, partially broken away, of the member of FIG. 6 with the culture medium added;
  • FIG. 8 is a top plan view, partially broken away, of an alternative elongated member having culture medium extending about the inner end;
  • FIG. 10 is an exploded perspective view of the elongated member and the guide member and brush illustrating the spreading of the inoculum.
  • Prior Art A typical prior art device is shown in FIG. 1.
  • a glass container tube 2 has a threaded cap 4 and contains a stick 6 having a frame end 8 for the support of a solid culture medium 10. It will be noted that the end portion 12 of the culture medium 10 is in contact with the interior surface of the container 2.
  • a device for making a culture of micro-organisms in accordance with the invention has a transparent container 22 of, for example, glass or a plastic such as an acrylic resin such as methyl methacrylate or a polycarbonate resin.
  • an elongated member 24 has an inner end 25 and a recessed portion 26 in opposed substantially that faces (only one being shown). Each recessed portion is intermediate the ends of the elongated member 24 and has multiple small protrusions 30 to facilitate the retention of a body 32 of a solid culture medium in the recessed portions.
  • the culture medium is preferably flush with the adjoining portions the adjacent face 28.
  • elongated member 24 are guided by opposed grooves 36, 36 in hollow guide member 38 which has a cylindrical portion 40 (FIG. 5) provided with ridges 42 which sealingly engage a cylindrical entrance portion 44 of container 22.
  • Guide member 38 is also provided with opposed flats 46, 46 which engage the flat top 48 and the flat bottom 50 of container 22 (FIGS. 9 and 10).
  • the inner end of guide member 38 has a pair of opposed brush members 52, 52 positioned adjacent grooves 36, 36 so as to engage elongated member 24 as it is inserted into container 22.
  • Each brush member 52 has three spaced projections 54 for engaging the elongated member 24.
  • Guide member 38 has a cylindrical entrance portion 56 which is engaged by a plug portion 58 (FIG. 10) of member 24 having a peripheral ridge 60 to seal closed the end of guide member 38.
  • the outer end of elongated member 24 is in the form of handle 64.
  • the guide member will be made of a resilient plastic such as, for example, polyethylene or polypropylene and the brush member 52, 52 will be integral therewith permitting the formation of the guide member and the brush members in a single forming operation from the same material.
  • the culture medium will be selected depending upon the micro-organisms involved. Suitable solid culture mediums are well known to the an. Reference may be had, for example, to the culture mediums disclosed in US. Pat. No. 3,368,549 the disclosure of which is incorporated herein by reference. Agar culture mediums are preferred since their solidity is readily controlled by varying the percent of Agar. Further typical culture mediums are set forth below:
  • a device for making a culture of micro-organisms comprising: an elongated member, a culture medium supported by said member intermediate the ends thereof, a container for the elongated member having an open end, brush means mounted in the container and positioned for contacting the elongated member intermediate its ends so as to brush over at least a portion of the culture medium on insertion of the elongated member into the container and means to seal the open end of the container.
  • the device of claim 1 in which the culture medium extends to and covers at least a portion of the inner end of the elongated member.
  • sealing means includes a plug on the elongated member.
  • a hollow guide member is mounted in the open end of the container to guide the elongated member and restrict its movement towards the interior surfaces of the container.
  • the device claim 1 in which the container is transparent. 10. The device of claim 9 in which the container has a flat portion opposite the elongated member for viewing the culture medium.

Abstract

A device for making a culture of micro-organisms has an elongated member which advantageously supports a culture medium on each of two opposite flat faces. A container having an open end is provided for the elongated member. A brush mounted in the container contacts the elongated member intermediate its ends. The open end of the container has removable means to seal it. In a typical operation, the elongated member is removed from the container and the end thereof brought into contact with the area of the patient suspected of having micro-organsims. On returning the elongated member to the container it passes the brush which wipes along the member to brush the inoculum from the end along the culture medium. Advantageously, the container has a guide member to guide the elongated member and restrict its movement toward the interior surfaces of the container. Preferably the brush forms a part of the guide member and the elongated member has a plug adapted to form a seal with the guide member to permit the withdrawal of the elongated member from the container either independently of the guide member or together with the guide member.

Description

United States Patent [72] Inventors Anthony J. Calabrese Malvern; Joseph F. Pagano, Paoli, both of Pa. [211 App]. No. 848,212 [22] Filed Aug. 7, 1969 [45] Patented Oct. 26, 1971 [73] Assignee Smith Kline & French Laboratories Philadelphia, Pa.
[54] DEVICE FOR MAKING A CULTURE OF MICRO- ORGANISMS 10 Claims, 10 Drawing Figs.
[52] U.S.C1 195/139, 195/100,l18/l21, 15/210 [51] Int. Cl Cl2b l/02 [50] Field of Search 195/139 LE, 139
[56] References Cited UNITED STATES PATENTS 3,308,039 3/1967 Nelson 195/139 LE Primary Examiner-Alvin E. Tanenholtz Attorney-Busser, Smith & Harding ABSTRACT: A device for making a culture of micro-organisms has an elongated member which advantageously supports a culture medium on each of two opposite flat faces. A container having an open end is provided for the elongated member. A brush mounted in the container contacts the elongated member intermediate its ends. The open end of the container has removable means to seal it. In a typical operation, the elongated member is removed from the container and the end thereof brought into contact with the area of the patient suspected of having micro-organsims. On returning the elongated member to the container it passes the brush which wipes along the member to brush the inoculum from the end along the culture medium. Advantageously, the container has a guide member to guide the elongated member and restrict its movement toward the interior surfaces of the container. Preferably the brush forms a part of the guide member and the elongated member has a plug adapted to form a seal with the guide member to permit the withdrawal of the elongated member from the container either independently of the guide member or together with the guide member.
PATENTEDUCT 2 6 19H SHEET 10F 2 PRlOR ART FIG.
FIG. 6.
FIG. 7.
INVENTORS a O l E RM A 8 M AA P A 4 CF 0 YW NS u 0 U N Y A B Ii ATTORNEYS SHEET 2 BF 2 INVENTORS ANTHONY J. CALABRESE & JOSEPH F. PAGANO BM M lllII -IIIlllll !IIIII -IIIIIIIII PATENTEDUCT 2 6 I971 ATTORNEYS DEVICE FOR MAKING A CULTURE OF MICRO- ORGANISMS BACKGROUND OF THE INVENTION Devices for making a culture of microorganisms having a culture medium which can be brought directly into contact with an area of a patients body and then returned to a sealed container for growing micro-organisms picked up are known to the art as is seen, for example, in the disclosure of U.S. Pat. No. 3,368,549, issued Feb. 13, 1968. Such devices have as their intended purpose providing office diagnosis within 24 hours without the necessity for a laboratory. In heretofore known devices there has been difficulty in assessing the results achieved due to the fact the inoculum is heavily concentrated in a single area and dilution is not possible. Isolated colonies are not seen because of restricted surface area. Further, difficulty has been encountered due to the face that the inoculated culture medium comes into contact with the sides of the container and pennissible movement disrupts growth of micro-organisms. In addition, the visibility through the container has been poor. All of these problems are solved in the present invention.
SUMMARY OF THE INVENTION A device for making a culture of micro-organisms has an elongated support member which carries a culture medium supported by said member preferably intermediate the ends thereof. A container having an open end is adapted to contain the elongated member and has a brush mounted therein to brush over the inner end of the elongated member and at least a portion of the culture medium on insertion of the elongated member into the container. Preferably the container is transparent and has flat surfaces through which the culture medium is viewed. A seal for the open end of the container is provided and it advantageously forms a part of the elongated member. Advantageously a hollow guide member guides the elongated member within the container to restrict its movement towards the interior surfaces of the container. Preferably the brush forms a part of said guide member and the elongated member has a plug engaging the guide member to seal the container. Advantageously the guide member is removable.
DESCRIPTION OF THE DRAWINGS FIG. 1 is an elevational view of a prior art device;
FIG. 2 is an elevational view of a device in accordance with the invention;
FIG. 3 is a vertical section taken on the plane indicated by the line 3-3 in FIG. 2;
FIG. 4 is an end of view of the guide member and brush of the device of FIG. 2;
FIG. 5 is a side elevation of the structure of FIG. 4;
FIG. 6 is a top plan view of the elongated support member of the device of FIG. 2 without the culture medium;
FIG. 7 is a top plan view, partially broken away, of the member of FIG. 6 with the culture medium added;
FIG. 8 is a top plan view, partially broken away, of an alternative elongated member having culture medium extending about the inner end;
FIG. 9 is an exploded broken away view of the device of FIG. 2; and
FIG. 10 is an exploded perspective view of the elongated member and the guide member and brush illustrating the spreading of the inoculum. Prior Art A typical prior art device is shown in FIG. 1. Here a glass container tube 2 has a threaded cap 4 and contains a stick 6 having a frame end 8 for the support of a solid culture medium 10. It will be noted that the end portion 12 of the culture medium 10 is in contact with the interior surface of the container 2.
Preferred Embodiment of the Invention Referring now to FIG. 2 a device for making a culture of micro-organisms in accordance with the invention has a transparent container 22 of, for example, glass or a plastic such as an acrylic resin such as methyl methacrylate or a polycarbonate resin. As shown in FIGS. 6 and 7, an elongated member 24 has an inner end 25 and a recessed portion 26 in opposed substantially that faces (only one being shown). Each recessed portion is intermediate the ends of the elongated member 24 and has multiple small protrusions 30 to facilitate the retention of a body 32 of a solid culture medium in the recessed portions. The culture medium is preferably flush with the adjoining portions the adjacent face 28.
The side edges of elongated member 24 are guided by opposed grooves 36, 36 in hollow guide member 38 which has a cylindrical portion 40 (FIG. 5) provided with ridges 42 which sealingly engage a cylindrical entrance portion 44 of container 22. Guide member 38 is also provided with opposed flats 46, 46 which engage the flat top 48 and the flat bottom 50 of container 22 (FIGS. 9 and 10). The inner end of guide member 38 has a pair of opposed brush members 52, 52 positioned adjacent grooves 36, 36 so as to engage elongated member 24 as it is inserted into container 22. Each brush member 52 has three spaced projections 54 for engaging the elongated member 24.
Guide member 38 has a cylindrical entrance portion 56 which is engaged by a plug portion 58 (FIG. 10) of member 24 having a peripheral ridge 60 to seal closed the end of guide member 38. The outer end of elongated member 24 is in the form of handle 64.
Advantageously the guide member will be made of a resilient plastic such as, for example, polyethylene or polypropylene and the brush member 52, 52 will be integral therewith permitting the formation of the guide member and the brush members in a single forming operation from the same material.
The culture medium will be selected depending upon the micro-organisms involved. Suitable solid culture mediums are well known to the an. Reference may be had, for example, to the culture mediums disclosed in US. Pat. No. 3,368,549 the disclosure of which is incorporated herein by reference. Agar culture mediums are preferred since their solidity is readily controlled by varying the percent of Agar. Further typical culture mediums are set forth below:
A. Moni-Tubefor isolation and presumptive identification of Candida Media-BIGGY Agar (formerly Nickerson) Formula Distilled water I l. Bismuth Ammonium Citrate 5 g. Sodium Sulfite 3 g. Dextrose l0 g. Glycine l0 g. Yeast Extract l g. Agar 2.0% of weight of the total formula.
B. Hemolytic Tubefor isolation and presumptive identification of B-Hemolytic Streptococci Media-Trypticase Soy Agar with 5% Defibrinated Sheep Defibrinated Sheep blood 5% by weight of the total formula C. Bacteruria Tube-for isolation l l. bacteria from urine.
Media-Eosin Methylene Blue Agar Formula Distilled water I Different formulae can be used on opposite sides of the elongated member for example, the formula of A above on one side and the immediately above formula on the other side.
OPERATION In operation the elongated member 24 is removed from container 22 by withdrawing through guide member 38. The end 25 is brought into contact with the area of the patient which is suspected of having relevant micro-organism. The elongated member is then returned into container 22 with grooves 36, 36 guiding it through brushes 52, 52 and preventing it from touching the interior surfaces of container 22. As the end 25 of elongated member 24 passes through brushes 52, 52 the portions 54 wipe the inoculum from end 25 onto the bodies 32, 32 of culture medium carried in the recessed portions 26, 26 in faces 28, 28. As illustrated in FliG. this results in placing three straight lines 68, 70 and 72 of inoculum on each body of culture medium which dilutes the inoculum and provides isolated colonies.
If it is desired to closely inspect the elongated member 24 during the growth of micro-organisms this can be done readily by removing the member 24 together with the guide member 38 thus preventing brushes 52, 52 from further brushing the culture medium.
ALTERNATIVE EMBODIMENT Referring now to FIG. 8, if desired, a modified elongated member 80 can be employed. Member 80 is the same as member 24 but provides for a body 82 of culture medium on both sides (only one side being shown) which extends beyond the inner end of member 80 as indicated at 84. To facilitate this arrangement, the body 82 of culture medium is carried in a recessed portion 86 on each side, protrusions 88 being employed to assist in retaining the body of culture medium. Each recessed portion 86 extends to the end 90 of member 88.
The above-described embodiments are illustrative and are not intended to be limiting.
We claim:
1. A device for making a culture of micro-organisms comprising: an elongated member, a culture medium supported by said member intermediate the ends thereof, a container for the elongated member having an open end, brush means mounted in the container and positioned for contacting the elongated member intermediate its ends so as to brush over at least a portion of the culture medium on insertion of the elongated member into the container and means to seal the open end of the container.
2. The device of claim 1 in which the culture medium extends to and covers at least a portion of the inner end of the elongated member.
3. The device of claim 1 in which the sealing means includes a plug on the elongated member.
4. The device of claim 1 in which the brush is removably mounted adjacent the open end of the container.
5. The device of claim I in which a hollow guide member is mounted in the open end of the container to guide the elongated member and restrict its movement towards the interior surfaces of the container.
6. The device of claim 1 in which a body of culture medium is supported on each of two opposite sides of the member elongated.
7. The device of claim 6 in which the culture medium bodies on opposite sides of the elongated member are different.
8. The device of claim 6 in which the guide member is removable.
9. The device claim 1 in which the container is transparent. 10. The device of claim 9 in which the container has a flat portion opposite the elongated member for viewing the culture medium.
i t l 8 I9

Claims (9)

  1. 2. The device of claim 1 in which the culture medium extends to and covers at least a portion of the inner end of the elongated member.
  2. 3. The device of claim 1 in which the sealing means includes a plug on the elongated member.
  3. 4. The device of claim 1 in which the brush is removably mounted adjacent the open end of the container.
  4. 5. The device of claim 1 in which a hollow guide member is mounted in the open end of the container to guide the elongated member and restrict its movement towards the interior surfaces oF the container.
  5. 6. The device of claim 1 in which a body of culture medium is supported on each of two opposite sides of the member elongated.
  6. 7. The device of claim 6 in which the culture medium bodies on opposite sides of the elongated member are different.
  7. 8. The device of claim 6 in which the guide member is removable.
  8. 9. The device claim 1 in which the container is transparent.
  9. 10. The device of claim 9 in which the container has a flat portion opposite the elongated member for viewing the culture medium.
US848212A 1969-08-07 1969-08-07 Device for making a culture of microorganisms Expired - Lifetime US3616265A (en)

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ES (1) ES381794A1 (en)
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Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2424384A1 (en) * 1973-05-24 1974-12-19 Smithkline Corp DEVICE FOR PRODUCING A MICRO-ORGANISM CULTURE
US3961696A (en) * 1975-10-20 1976-06-08 Smithkline Corporation Device for making a culture of CO2 requiring organisms
US3966552A (en) * 1975-04-14 1976-06-29 Smithkline Corporation Device for making a culture of micro-organisms
US4073695A (en) * 1976-08-11 1978-02-14 Data Packaging Corporation Leighton tube
US4082614A (en) * 1975-12-10 1978-04-04 Bio-Syn, Inc. Means for conveying pathological specimens safely to places of identification
WO1982000834A1 (en) * 1980-09-10 1982-03-18 L Brown Antibiotic testing vessel
US4558520A (en) * 1983-11-30 1985-12-17 Forde Jr George S Self-wiping universal liquid level gauge
US4859586A (en) * 1985-08-26 1989-08-22 Eliahu Eisenberg Device for cultivating bacteria
US4891859A (en) * 1988-12-14 1990-01-09 Napoleon Tremblay Engine oil dip stick indicator wiper
DE10061655A1 (en) * 2000-12-11 2002-06-20 Vermicon Ag In situ hybridization arrangement for the specific detection of microorganisms
US20050023672A1 (en) * 2003-07-01 2005-02-03 Affymetrix, Inc. Device and method for immersed array packaging and processing
US20100083774A1 (en) * 2008-10-04 2010-04-08 Eppendorf Ag Forensic pipette
US20100083773A1 (en) * 2008-10-04 2010-04-08 Eppendorf Ag Sample carrier
US20100167415A1 (en) * 2008-12-30 2010-07-01 Eppendorf Ag Aliquotting device
US20100193524A1 (en) * 2009-02-05 2010-08-05 Eppendorf Ag Preserving container

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA955163A (en) * 1971-03-16 1974-09-24 Miles Laboratories, Inc. Testing device for microorganisms
GB2141136B (en) * 1983-06-08 1987-03-04 Basildon Moulding Company Limi Dip slide
IT1237781B (en) * 1989-11-21 1993-06-17 Diesse Diagnostica DEVICE FOR THE STORAGE OF SAMPLES AND FOR THE INSULATION OF GERMS IN THESE SAMPLES CONTAINED FOR MICROBIOLOGICAL EXAMINATIONS.

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2424384A1 (en) * 1973-05-24 1974-12-19 Smithkline Corp DEVICE FOR PRODUCING A MICRO-ORGANISM CULTURE
US3862013A (en) * 1973-05-24 1975-01-21 Smithkline Corp Device for making a culture of micro-organisms
US3966552A (en) * 1975-04-14 1976-06-29 Smithkline Corporation Device for making a culture of micro-organisms
DE2615546A1 (en) * 1975-04-14 1976-10-28 Smithkline Corp DEVICE FOR PRODUCING A CULTURE OF MICRO-ORGANISMS
US3961696A (en) * 1975-10-20 1976-06-08 Smithkline Corporation Device for making a culture of CO2 requiring organisms
US4082614A (en) * 1975-12-10 1978-04-04 Bio-Syn, Inc. Means for conveying pathological specimens safely to places of identification
US4073695A (en) * 1976-08-11 1978-02-14 Data Packaging Corporation Leighton tube
WO1982000834A1 (en) * 1980-09-10 1982-03-18 L Brown Antibiotic testing vessel
US4326028A (en) * 1980-09-10 1982-04-20 Brown Lewis R Antibiotic testing vessel
US4558520A (en) * 1983-11-30 1985-12-17 Forde Jr George S Self-wiping universal liquid level gauge
US4859586A (en) * 1985-08-26 1989-08-22 Eliahu Eisenberg Device for cultivating bacteria
US4891859A (en) * 1988-12-14 1990-01-09 Napoleon Tremblay Engine oil dip stick indicator wiper
DE10061655A1 (en) * 2000-12-11 2002-06-20 Vermicon Ag In situ hybridization arrangement for the specific detection of microorganisms
WO2002048398A2 (en) * 2000-12-11 2002-06-20 Vermicon Ag In situ hybridization system for specifically detecting microorganisms
WO2002048398A3 (en) * 2000-12-11 2003-05-15 Vermicon Ag In situ hybridization system for specifically detecting microorganisms
US20050023672A1 (en) * 2003-07-01 2005-02-03 Affymetrix, Inc. Device and method for immersed array packaging and processing
US20100083774A1 (en) * 2008-10-04 2010-04-08 Eppendorf Ag Forensic pipette
US20100083773A1 (en) * 2008-10-04 2010-04-08 Eppendorf Ag Sample carrier
US20100167415A1 (en) * 2008-12-30 2010-07-01 Eppendorf Ag Aliquotting device
US20100193524A1 (en) * 2009-02-05 2010-08-05 Eppendorf Ag Preserving container

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DE2034923C3 (en) 1979-07-12
CA952836A (en) 1974-08-13
DE2034923A1 (en) 1971-02-18
DE2034923B2 (en) 1978-11-16
NL172172C (en) 1983-07-18
GB1246070A (en) 1971-09-15
ES381794A1 (en) 1972-12-01
LU61458A1 (en) 1970-10-21
FR2057723A5 (en) 1971-05-21
NL7011646A (en) 1971-02-09
NL172172B (en) 1983-02-16
CH540977A (en) 1973-08-31
BE752895A (en) 1971-01-04

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