US3408846A - Hypodermic needles - Google Patents

Hypodermic needles Download PDF

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Publication number
US3408846A
US3408846A US590933A US59093366A US3408846A US 3408846 A US3408846 A US 3408846A US 590933 A US590933 A US 590933A US 59093366 A US59093366 A US 59093366A US 3408846 A US3408846 A US 3408846A
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Prior art keywords
die
cannula
jaws
hub
billet
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Expired - Lifetime
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US590933A
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English (en)
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Schofield Hubert Percival
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Individual
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B21—MECHANICAL METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
    • B21C—MANUFACTURE OF METAL SHEETS, WIRE, RODS, TUBES OR PROFILES, OTHERWISE THAN BY ROLLING; AUXILIARY OPERATIONS USED IN CONNECTION WITH METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL
    • B21C37/00—Manufacture of metal sheets, bars, wire, tubes or like semi-manufactured products, not otherwise provided for; Manufacture of tubes of special shape
    • B21C37/06—Manufacture of metal sheets, bars, wire, tubes or like semi-manufactured products, not otherwise provided for; Manufacture of tubes of special shape of tubes or metal hoses; Combined procedures for making tubes, e.g. for making multi-wall tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3286—Needle tip design, e.g. for improved penetration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B21—MECHANICAL METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
    • B21C—MANUFACTURE OF METAL SHEETS, WIRE, RODS, TUBES OR PROFILES, OTHERWISE THAN BY ROLLING; AUXILIARY OPERATIONS USED IN CONNECTION WITH METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL
    • B21C23/00—Extruding metal; Impact extrusion
    • B21C23/02—Making uncoated products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B21—MECHANICAL METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
    • B21C—MANUFACTURE OF METAL SHEETS, WIRE, RODS, TUBES OR PROFILES, OTHERWISE THAN BY ROLLING; AUXILIARY OPERATIONS USED IN CONNECTION WITH METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL
    • B21C23/00—Extruding metal; Impact extrusion
    • B21C23/02—Making uncoated products
    • B21C23/04—Making uncoated products by direct extrusion
    • B21C23/08—Making wire, bars, tubes
    • B21C23/12—Extruding bent tubes or rods
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B21—MECHANICAL METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
    • B21C—MANUFACTURE OF METAL SHEETS, WIRE, RODS, TUBES OR PROFILES, OTHERWISE THAN BY ROLLING; AUXILIARY OPERATIONS USED IN CONNECTION WITH METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL
    • B21C23/00—Extruding metal; Impact extrusion
    • B21C23/02—Making uncoated products
    • B21C23/04—Making uncoated products by direct extrusion
    • B21C23/14—Making other products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B21—MECHANICAL METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
    • B21G—MAKING NEEDLES, PINS OR NAILS OF METAL
    • B21G1/00—Making needles used for performing operations
    • B21G1/08—Making needles used for performing operations of hollow needles or needles with hollow end, e.g. hypodermic needles, larding-needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/19—Constructional features of carpules, syringes or blisters
    • A61M2205/192—Avoiding coring, e.g. preventing formation of particles during puncture
    • A61M2205/195—Avoiding coring, e.g. preventing formation of particles during puncture by the needle tip shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/329—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
    • A61M5/3291—Shafts with additional lateral openings

Definitions

  • Such billet is disposed in the cavity of a female die and is extruded into a cupshaped recess corresponding to the hub to be formed and into a bore extending from the recess to form the tubular cannula with the end portion of the latter remote from the hub being deflected so as to assume a longitudinal curvature, whereupon the end portion of the cannula, at the inside of its curve, is laterally compressed or pinched to define an ear which is severed from the cannula to de fine a longitudinal slit at a side of the tapered end terminating in a solid point.
  • the apparatus for performing the foregoing operations has a die assembly made up of parts which are automatically displaced relative to each other in the necessary sequence.
  • the present invention relates to hypodermic needles, and particularly to a method and apparatus for producing the same.
  • hypodermic needles comprise a tubular element or cannula of regular cross section and a hub or appendage to which it is attached and by which the cannula is mounted on a syringe.
  • the joint between the two is generally unsatisfactory for a number of reasons not the least important being that a tube of regular cross section projecting from a larger body, by virtue of its connection at one of its ends to said body, must be relatively weak at the joint.
  • the primary object of this invention is to make possible the manufacture of nontoxic hypodermic needles at such low cost that they may be disposable, that is, used for one injection only and then thrown away.
  • Another object is to provide hypodermic needles that are substantially stronger than those currently in use.
  • a further object is to perform the various stages of manufacture automatically.
  • a method of producing a hypodermic needle having a cannula extending from an integral hub comprises locating an annular billet of nontoxic material in a relatively wide cup-shaped cavity of a female die which corresponds substantially to the external configuration of the hub to be formed and has a bore extending from its base corresponding to the external diameter of the cannula to be formed, subjecting the billet to an impact extrusion operation so as to shape said billet into said hub with the cannula extending therefrom, deflecting the end portion of the cannula remote from the hub during the impact extrusion so that such end portion is curved slightly out of the common axis of the cannula and hub, laterally compressing or pinching the curved end portion at the inside of the curve to form a laterally projecting ear and substantially instantaneously severing said ear completely to leave a symmetrically tapered end of the cannula having a solid point with a longitudinal slit in said end immediately in back of such point at the location
  • Apparatus for performing the above method comprises power operated ram means for imparting impact extrusion pressure to an annular billet of nontoxic material, die means having recesses therein for shaping the billet on impact of the ram into the form of a hollow hub and an integral hollow cannula part, the end of which remote from the hub is curved longitudinally simultaneously with formation of said cannula part in said die means; means displaceable laterally of said die for compressing a portion of the periphery of the curved end of said cannula part at the inside of the curve to form an ear therefrom and means for severing said ear at the termination of said lateral compression simultaneously to form a tapered end on said cannula which is symmetrical about the axis thereof and has a solid point and a longitudinal slit communicating with the interior of said cannula and located immediately in back of said point where said ear has been severed.
  • the apparatus includes a multiple part die comprising a main part which has a first recess adapted to receive an annular billet of nontoxic material and having a shape consistent with the external periphery of the hub of a needle to be produced, a second recess disposed coaxially of, and in communication with the first recess to form a portion of an integral cannula part between the hub and the remote end of a needle to be produced and a third recess formed in a planar face of the main part which contains an extension of the common axis of both the first and second recesses and is of semicircular cross-section and tapering to a point, two other die parts in the form of jaws oppositely displaceable in directions laterally of said common axis and have recesses which, in cross-section, constitute opposite quadrants of a circle and are longitudinally tapered to a point, inclined shearing edges on the oppositely displaceable jaws, guide faces on said main part for sliding engagement by the jaws during displacement thereof
  • the annular billet consists of a short length of aluminum tubing, with impact extrusion alone being utilized in the production of the needle and its integral hub.
  • the needles may be of stainless steel, a light metal alloy, or of a plastic material.
  • the cross-section of the cannula or needle portion where it merges into the hub part maybe varied as desired, and the external periphery of the needle need not be concentric with the axis of the bore.
  • the needle may have a corrugated external periphery or one in which a bulge is formed at one peripheral part diametrically opposite a peripheral recess.
  • the needle may be substantially of triangular section with the apices thereof being rounded.
  • the hub may be of any desired shape, for example, circular or hexagonal, or it may have a flange, the shape of which is such that it has parallel opposite side faces terminating in semicircular curved portions, all of which may be of a nonslip nature.
  • the material and the shape of the finished needle is such that heat treatment for hardening the same is not required.
  • FIG. 1 is a sectional view of the die parts of an apparatus in accordance with one embodiment of this invention, with a needle produced therein by an impact extrusion operation being shown in full lines and partly in section and with a billet for the production of a needle being shown in broken lines;
  • FIG. 2 is a perspective exploded view of a portion of the die parts
  • FIG. 3 is a sectional view taken along the line III-III on FIG. 1;
  • FIG. 4 is an elevational view, partly in section, which schematically illustrates an apparatus incorporating the die parts of FIG. 1, but shown on a smaller scale;
  • FIG. 5 is a sectional view taken along the line VV on FIG. 1;
  • FIG. 6 is an elevational view, partly in section, of the unitary hub and cannula of a needle at the first stage of production;
  • FIG. 7 is a view of a portion of the cannula at the second stage of production
  • FIG. 8 is a sectional view taken along the line VIII- VIII on FIG. 7;
  • FIG. 9 is a view of the pointed end of the cannula at the termination of the final stage of production
  • FIG. 10 is an end view of the cannula part of the needle of FIG. 9.
  • FIG. 11 is an elevational view, partly in, longitudinal section, of the finished needle.
  • the multiple part female die may be formed in a number of ways, and the annular or short tube-shaped billet may be fed into one of the die parts either from that end thereof at which the impact extrusion ram enters the die part, or from the opposite end of said die part.
  • the billet or workpiece remains stationary therein by virtue of a friction-fit with the inner peripheral wall of said part until engaged by the ram which may be operated hydraulically or mechanically through a spring loading.
  • a die assembly is shown to comprise a female die formed of four parts 10, 11, 12 and 13.
  • the die parts 10 and 11 are relatively displaceable to enable an annular or short tube shaped metallic or plastic billet or workpiece 14 to be fed into the bore of the part 10 at the opposite end thereof to that at which a ram or male die 15 of the die assembly enters to perform the impact extrusion operation.
  • the interengaging ends of the die parts 10, 11 are complementarily formed (FIGS. 1, 2 and 4) to facilitate accurate realignment following separation of die part 10 from part 11 and the insertion of a billet into the lower end of die part 10.
  • the billet is preferably of uniform wall thickness with its end edges appropriately tapered or' rounded.
  • the part 11 has an internal cup-shaped compartment 16 which is coaxial with the bore of the part 10 and the shape of which resembles the external shape of the hubs of the needles to be formed.
  • compartment 16 tapers gradually to a constriction or neck portion 17 (FIG. 1) of the die having a diameter equal to that of the cannula portions of the needles and opening into a bore 18 which is wider than said intended diameter of the cannula portions.
  • the diameter of the cannula portion of each needle is determined by the cross-section of the constriction or neckportion 17 and that the diameter of the material passing through said constriction will not subsequently increase despite the larger diameter of the bore 18.
  • the taper 19 in die part 11 which commences slightly above the horizontal plane containing the upper faces of the jaws 12 and 13 is continued in the remaining rear portion 11a of the die part 11 as shown in FIGS. 1 and 5 so that a conical recess 23 of semicircular section is formed in the face 22 and tapers to a point at a position which is spaced from the neck 17 by a distance equal to the length of the needles to be formed.
  • the recesses 24 of such jaws together with the recess 23 of face 22 of die part 1-1 define a tapered bore consistent with the desired shape of the pointed ends of the needles to be made.
  • each of jaws 12 and 13 has a shearing edge 25 adapted to sever any material in the path of the said edges 25 as the jaws 12 and 13 approach their extreme positions of displacement towards each other.
  • rollers 26 (FIGS. 1 and 4) which are adapted for engagement by inclined surfaces 27 on cams 28 which may be displaced longitudinally of the die by the same power source provided for displacing the ram or male die member 15.
  • die member 15 has a tapered forepart 29 extending from an annular shoulder 30 to a leading face 31 from the center of which there projects a protuberance 32.
  • protuberance 32 initiates the formation of the bore in the cannula part of the needle in the region of the hub, which bore is then maintained automatically during the extrusion of the cannula part.
  • oil or other fluid under pressure is supplied from a suitably valved or otherwise controlled source through a duct 41 and bore 42 into a chamber 43 of the die part 10 housing the ram 15 in order to displace the ram downwardly relative to said die part 10 when it is desired to operate on a billet 14 to effect the production of a needle by impact extrusion.
  • Reverse or return displacement of the ram, on the release of the hydraulic or other pressure is effected by a spring 44 located between the closed end of die part 10 and an enlarged head 45 on a rod 46 projecting from the ram 15 through said closed end.
  • cams 28 may be downwardly displaced to enable their inclined surfaces 27 to force the rollers 26 inwardly towards each other and thus inwardly displace the jaws 12 and 13, by hydraulic means including rams 47 operating in cylinders 48 carried by the die part 11 and into which ducts 49 open to deliver oil under pressure when a predetermined pressure is attained in the duct 41 sufficient to open a pressure relief valve 50, that is, at the termination of the downward stroke of the ram 15.
  • return movement of the rams 47 is effected by springs 51 acting upwardly on rods extending from the rams or pistons 47.
  • the usual oil seals for the rams 15, 47 and for the rods extending out of chamber 43 and cylinders 48 may be provided, as at 52.
  • the return or laterally outward displacement of the jaws 12 and 13 is effected by a spring 53 (FIGS. 2 and 3) which may be seated in opposed recesses of the jaws, and such return movement is limited by engagement of the jaws with fixed stops 54 on a support 55 (FIG. 2).
  • the die part 10 may be manually raised from the die part 11 when it is desired to insert a billet into part 10 for a needle forming operation.
  • die part may be provided with lugs 56 adapted to slide longitudinally along pillars 57 mounted on the stationary die part 11 by way of lugs 58 (FIG. 4).
  • any suitable reliable means may be employed for holding together die parts 10 and 11 during the pressure stroke in the impact extrusion operation, and to permit the de scribed relative movement of such die parts at the end of the operation.
  • manually operable and well-known over-center latches 59 may be pivotally mounted at diametrically opposed positions on the wall of die part 11 for engagement with keepers 60 which are secured at similar diametrically opposed positions on the wall of die part 10 as is shown diagrammatically on FIG. 2.
  • the tapered part 29 of the ram enters the bore in the billet and momentarily tends to radially squeeze the latter to cause the length of the billet to increase while still retaining its tubular form.
  • the shoulder 30 comes into contact with the upper end of the billet 14 to force this into the part 11 of the die, thereby forming the tapered hub part 33 and a tubular part 34 below the latter.
  • the protuberance 32 functions to maintain an axial bore in the tubular part 34 at the neck where the material leaves the hub 33 and commences to form what finally becomes the cannula portion of each needle.
  • the jaws 12, 13 are spaced apart by a distance sufficient to allow the lower end of the tubular part to take the position shown in broken lines at 37 in FIG. 5, the bend in the lower end of the tube from the axis of symmetry of the remaining part of the tube being caused by the taper of the semi-circular recess 23 of the die part 11.
  • the billet 14 has thus been converted into the form shown in FIG. 6, that is, with an open end 35 in the bent portion of the tube- 34 remote from the hub 33.
  • FIGS. 9 and 10 they operate to sever the ear 36 from the tube to produce a pointed end as shown in FIGS. 9 and 10, that is, with the end tapered symmetrically about the axis of the tube and with a longitudinal slit 38 immediately in back of a solid pointed end 39.
  • the finished product is shown in FIG. 11 and from this it will be appreciated that the cannula and hub of the needle are integrally formed and that penetration of the pointed end of the needle into the skin of a patient at the desired site of injection of the needle contents is eifected by a piercing and spreading operation, as distinct from a cutting action.
  • the finished needle may be removed from die part 11 in any desired manner, for example, upwardly from the end at which the ram 15 operates upon separation of die part 10 from part 11, or sideways by dividing the upper portion of the die part 11 longitudinally through the axis of symmetry of the cup-shaped recess 16 and by enabling one of said divided parts to be displaced relatively to the other.
  • an apparatus in accordance with the invention may have a number of such die assemblies provided therein for simultaneous operation from a common source of fluid under pressure, whereby a corresponding number of needles are produced simultaneously.
  • a method of producing a hypodermic needle having a cannula extending from an integral hub comprising extruding an annular billet of nontoxic material into a relatively wide cupshaped recess of a female die which corresponds substantially to the external configuration of the hub to be formed and has a bore extending from its base and diametrically dimensioned so that the material of said billet extruded through said bore defines the cannula to be formed, deflecting the formed cannula toward one side at the end thereof remote from the hub so that such end portion of the cannula is curved slightly out of the common axis of the cannula and hub, late-rally compressing said curved end portion at the inside of the curve to impart to said end portion a symmetrically taped configuration with an ear projecting from one side thereof, and substantially instantaneously serving said ear completely to leave a longitudinal slit in said tapered end portion immediately in back of a solid point.
  • Apparatus for producing hypodermic needles comprising power operated ram means for imparting impart extrusion pressure to an annular billet of nontoxic material, die mans having recesses therein for shaping the billet on impact of said ram into the form of a hollow hub and an integral hollow cannula projecting longitudinally therefrom, means in said die means to deflect to one side the end portion of said cannula part remote from the hub during formation of said cannula part so that said end portion is longitudinally curved toward said one side, means displaceable laterally of said die means for compressing a portion of the periphery at the inside of the curved end portion of said cannula part to form an ear projecting therefrom and means for severing said ear at the termination of the compression at said end portion thereby to form a tapered end on said cannula which is symmetrical about the axis thereof and has a longitudinal slit which communicates with the interior of said cannula immediately in back of a solid point.
  • Apparatus for producing hypodermic needles comprising a multiple part die including a main part which has a first recess adapted to receive an annular billet of nontoxic material and having a shape consistent with the external periphery of the hub of a needle to be produced, a second recess disposed coaxially of, and in communication with said first recess to form a portion of an integral cannula part between the hub and the remote end of a needle to be produced and a third recess formed in a planar face of said main part and containing an extension of the common axis of said first and second recesses,
  • said third recess being of semi-circular cross-section and tapering to a point
  • two other die parts which constitute jaws oppositely displaceable in directions laterally of said common axis and have recesses which in crosssection constitute opposite quadrants of a circle and are each longitudinally tapered to a point, shearing edges on said oppositely displaceable jaws along said recesses thereof, guide means on said main part for guiding engagement with said oppositely disposed jaws during displacement thereof, a ram movable into said first recess, power operated means operative to displace said ram into said first recess for applying impact extrusion pressure to an annular billet seated in said first recess, and means operative after said displacement of the ram to effect displacement of said jaws toward each other.
  • Apparatus as claimed in claim 2; wherein said means operative to displace said jaws includes cam means displaceable by the power operated means for the ram and cam follower means on said laterally displaceable jaws engageahle by said cam means to displace said jaws toward each other upon displacement of said cam means.

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
  • Materials For Medical Uses (AREA)
US590933A 1962-08-03 1966-10-31 Hypodermic needles Expired - Lifetime US3408846A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB29833/62A GB982780A (en) 1962-08-03 1962-08-03 Improvements in or relating to hypodermic needles

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US3408846A true US3408846A (en) 1968-11-05

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US (1) US3408846A (fr)
BE (1) BE635773A (fr)
CH (1) CH405615A (fr)
ES (1) ES290433A1 (fr)
FR (1) FR1365699A (fr)
GB (1) GB982780A (fr)
LU (1) LU44182A1 (fr)
NL (1) NL296134A (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3540112A (en) * 1967-01-18 1970-11-17 Knox Lab Inc Method for manufacturing a hypodermic needle
US3851516A (en) * 1973-07-23 1974-12-03 Combustion Eng Metal working apparatus
FR2481159A1 (fr) * 1980-04-28 1981-10-30 Poncin Philippe Procede de fabrication d'une aiguille hypodermique et ebauche d'aiguille obtenues par ce procede
US5776268A (en) * 1993-11-01 1998-07-07 Ethicon, Inc. Process for manufacturing surgical needles
US6142004A (en) * 1996-09-19 2000-11-07 Trw Occupant Restraint Systems Gmbh Load-bearing shaped part and a method for manufacturing shaped parts
WO2010132910A1 (fr) * 2009-05-19 2010-11-25 Lkr Leichtmetallkompetenzzentrum Ranshofen Gmbh Procédé de fabrication d'un petit tube à paroi fine en alliage de magnésium
US10682474B2 (en) 2012-11-21 2020-06-16 Amgen Inc. Drug delivery device

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK148312C (da) * 1981-09-11 1985-12-02 Christian Overland Hul kirurgisk engangsnaal, fortrinsvis af redon-typen
EP0278186A1 (fr) * 1987-02-13 1988-08-17 SOFIC Société Anonyme Aiguille pour seringue
FR2590176A1 (fr) * 1985-11-21 1987-05-22 Sofic Sa Aiguille pour seringue
JPH0616909B2 (ja) * 1987-05-29 1994-03-09 鈴木 高遠 水晶体嚢用切開刀の加工装置
FR2757405B1 (fr) * 1996-12-23 1999-08-06 Vermed Aiguille de traversee de septum non carottante

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2700906A (en) * 1950-10-30 1955-02-01 Cameron Iron Works Inc Die holder
US3054177A (en) * 1958-09-04 1962-09-18 Textron Inc Method of making valve lifter bodies or the like
US3078566A (en) * 1957-05-01 1963-02-26 Cold Forming Mfg Company Confined extrusion method of making hollow articles
US3101534A (en) * 1958-06-30 1963-08-27 Textron Inc Method of producing wrist pins or similar articles

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2700906A (en) * 1950-10-30 1955-02-01 Cameron Iron Works Inc Die holder
US3078566A (en) * 1957-05-01 1963-02-26 Cold Forming Mfg Company Confined extrusion method of making hollow articles
US3101534A (en) * 1958-06-30 1963-08-27 Textron Inc Method of producing wrist pins or similar articles
US3054177A (en) * 1958-09-04 1962-09-18 Textron Inc Method of making valve lifter bodies or the like

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3540112A (en) * 1967-01-18 1970-11-17 Knox Lab Inc Method for manufacturing a hypodermic needle
US3851516A (en) * 1973-07-23 1974-12-03 Combustion Eng Metal working apparatus
FR2481159A1 (fr) * 1980-04-28 1981-10-30 Poncin Philippe Procede de fabrication d'une aiguille hypodermique et ebauche d'aiguille obtenues par ce procede
US5776268A (en) * 1993-11-01 1998-07-07 Ethicon, Inc. Process for manufacturing surgical needles
US6142004A (en) * 1996-09-19 2000-11-07 Trw Occupant Restraint Systems Gmbh Load-bearing shaped part and a method for manufacturing shaped parts
WO2010132910A1 (fr) * 2009-05-19 2010-11-25 Lkr Leichtmetallkompetenzzentrum Ranshofen Gmbh Procédé de fabrication d'un petit tube à paroi fine en alliage de magnésium
CN102427894A (zh) * 2009-05-19 2012-04-25 Lkr轻金属能力中心兰斯霍芬有限责任公司 用于由镁合金生产小薄壁管的方法
JP2012527355A (ja) * 2009-05-19 2012-11-08 エーカーエル ライヒトメタルコンピテンツェントラム ランソフェン ゲーエムベーハー マグネシウム合金から形成される小型薄壁チューブを製造する方法
US9227235B2 (en) 2009-05-19 2016-01-05 Lkr Leichtmetallkompetenzzentrum Ranshofen Gmbh Method for producing a small thin-walled tube from a magnesium alloy
US10682474B2 (en) 2012-11-21 2020-06-16 Amgen Inc. Drug delivery device
US11344681B2 (en) 2012-11-21 2022-05-31 Amgen Inc. Drug delivery device
US11439745B2 (en) 2012-11-21 2022-09-13 Amgen Inc. Drug delivery device
US11458247B2 (en) 2012-11-21 2022-10-04 Amgen Inc. Drug delivery device

Also Published As

Publication number Publication date
CH405615A (de) 1966-01-15
ES290433A1 (es) 1963-12-01
FR1365699A (fr) 1964-07-03
GB982780A (en) 1965-02-10
NL296134A (fr) 1963-08-02
LU44182A1 (fr) 1963-10-01
BE635773A (fr)

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