US3394851A - Metered aerosol valve for use with compressed gas - Google Patents

Metered aerosol valve for use with compressed gas Download PDF

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US3394851A
US3394851A US488330A US48833065A US3394851A US 3394851 A US3394851 A US 3394851A US 488330 A US488330 A US 488330A US 48833065 A US48833065 A US 48833065A US 3394851 A US3394851 A US 3394851A
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valve stem
gas
chamber
tank
valve
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US488330A
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William G Gorman
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STWB Inc
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Sterling Drug Inc
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/44—Valves specially adapted therefor; Regulating devices
    • B65D83/52—Valves specially adapted therefor; Regulating devices for metering
    • B65D83/54—Metering valves ; Metering valve assemblies
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/42—Filling or charging means
    • B65D83/425—Delivery valves permitting filling or charging

Definitions

  • This invention in general relates to a valve construction similar to that illustrated in my United States Patent No. 3,128,924 with the difference that the present invention is adapted for use witth compressed gas, i.e., gases which are not mixed with the material to be expelled, as distinct from the patented valve which is for expelling materials with which the gas is miscible.
  • compressed gas i.e., gases which are not mixed with the material to be expelled
  • the invention contemplates the use of a valve, made in general of suitable materials such as plastics, the construction providing a tighter seal between the par-ts of the valve and the valve stem itself while at the same time the tank portion of the device is provided with a metering chamber of an improved design providing an additional compartment resulting in the trapping of gas in one compartment when material to be expelled is admitted to the chamber, and upon depression of the valve stem the trapped gas expands and pushes the material in the chamber through the stern and out to the atmosphere.
  • the construction is such that there is no compressed gas entrapment.
  • FIG. 1 is a cross sectional view through the new valve
  • FIG. 2 is a sectional view on line 2-2 of FIG. 1.
  • a flange or skirt which forms a part of a ferrule providing means for clamping or crimping the entire device to the mouth of a container.
  • This ferrule is shaped to the container mouth and is crimped to grasp the container at the top edge thereof as for instance at the mouth of a can or a bottle.
  • the container mouth is indicated by the reference numeral 12 but of course these containers take many different forms.
  • a gasket 14 solidly crimped to the container between a flange-like portion 16 of the ferrule which extends inwardly in an annular manner.
  • the tank flange 18 forms an integral part of the tank which is generally indicated by the reference numeral 20.
  • This tank may be generally cylindrical and extends downwardly as at 22 forming a chamber to be further described. It turns inwardly as at 24 forming a floor for the tank having at the central portion thereof an opening at 26.
  • the ferrule extends upwardly from flange 16 as at 28 and again inwardly as at 30 forming a top surface having a central aperture at 32 which provides for extension of the valve stem 34 therethrough. It will be seen that the top portion of the ferrule at 30 and the floor 24 of the tank are fixed with relation to each other and form in general an enclosure.
  • a gasket 36 On the floor 24 of the tank 20 there is provided a gasket 36 also having a central aperture through which the lower end of the valve 34 extends as at 38.
  • the gasket 36 is provided in close association with the outer wall or surface of the portion 38 of the valve stem 34 and seals the same, but at the same time this portion of the valve stem is provided with grooves 40 through which gas can escape into the interior of the chamber when the stem is in the FIG. 1, or closed position.
  • valve body 42 which is centrally hollow. At its lower end it is directed inwardly forming an annular shelf 44 against which a valve spring 46 finds its lowermost abutment. This spring encircles the valve stem and finds its upper abutment on a flange 48 which is fixed relative to the valve stem 34.
  • valve stem Inwardly of its lower portion, the valve stem is provided with an annular shoulder at 48 which reacts against another gasket 50 locked in position as will be described and this gasket forms the upper portion of a chamber in the lower portion of the tank 20.
  • the valve stem extends through an opening in the central portion and the shoulder 48 abuts it, which determines the upper limit of motion of the valve stem.
  • the central portion of the valve body 42 forms a chamber with which a port at 52 is in communication through the central opening 54 of the valve stem.
  • a meter insert plu generally indicated by the reference numeral 56. It will be seen that this plug may be provided with projections at the top and bottom so that it is firmly anchored with respect to gaskets 36 and '50.
  • This chamber is hollow providing openings for the valve stem so that it may operate between its uppermost and downwardmost positions, but its essential feature is that it is provided with a central generally annular bafiie which is indicated at 58.
  • This baflle has a lower edge 60 which terminates short of the upper surface of the gasket 36 and therefore it will be seen that not only is there an inner chamber formed in the tank but there is also an auxiliary outer chamber 62 of generally cylindrical form located separate from the inner chamber but communicating therewith at the lower end thereof.
  • the dip tube can be applied to member 38, in which case the device will work right side up, because the liquid is forced by the gas pressure up through the dip stick from the bottom of the container through orifice 40 into chamber 60.
  • port 52 opens to the chamber 60 and thus a charge is released.
  • the ports at 40 are closed off.
  • the operation is substantially the same using the dip tube with the container in upright condition or without the dip tube in inverted condition.
  • an aperture at 64 for the pressure filling of the container may also be provided an aperture at 64 for the pressure filling of the container, this being normally closed by a downturned flange 66 which is a part of the gasket 14, and it communicates with a groove 68.
  • a dispensing device for controlling the discharge of a metered amount of material from a container under pressure of immiscible gas, said device comprising a tank, means to secure the tank to a container, said tank having a metering chamber therein, means in said metering chamber forming a pair of chambers, one of the latter being radially spaced from the other, a valve stem, a spring for said valve stem normally urging the same to valveclosed condition, said valve stem being retractable against the action of the valve spring to open said valve stem to the atmosphere, and means communicating between the metering chamber and the interior of the container whereby both material to be propelled and the immiscible gas are located therein, the gas being in effect trapped in the outermost of said pair of chambers, whereupon when said valve stem is retracted the gas expands and expels material in the chamber out through the valve stem.
  • the dispensing device of claim 1 wherein the means providing the chambers comprises a baflle, said bafile extending downwardly from the top portion of said metering chamber to a point spaced from the bottom thereof.
  • the dispensing device of claim 1 wherein the means providing the chambers comprises a bafile, said baffie extending downwardly from the top portion of said metering chamber to a point spaced from the bottom thereof and surrounding the valve stem.
  • a metering valve construction for use with immiscible materials to be expelled by gas and comprising means providing a tank, a metering chamber in the tank, an insert plug in the chamber, means holding the plug in position, a valve stem extending through the tank and the plug, said valve stem having means for admitting material under pressure out to the atmosphere when in one position thereof and when in the other position thereof closing the metering chamber to the atmosphere, and means in said insert plug providing an inner and an outer chamber dividing the metering chamber into a plurality of chambers entrapping gas in the metering chamber.

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  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Nozzles (AREA)

Description

July 30, 1968 w. e. GORMAN 3,394,351
METERED AEROSOL VALVE FOR USE WITH COMPRESSED GAS Filed Sept. 20, 1965 l' a: l'// w 26 United States Patent 3,394,851 METERED AEROSOL VALVE FOR USE WITH COMPRESSED GAS William G. Gorman, East Greenbush, N.Y., assignor to Sterling Drug Inc., New York, N.Y., a corporation of Delaware Filed Sept. 20, 1965, Ser. No. 488,330 5 Claims. (Cl. 222402.2)
This invention in general relates to a valve construction similar to that illustrated in my United States Patent No. 3,128,924 with the difference that the present invention is adapted for use witth compressed gas, i.e., gases which are not mixed with the material to be expelled, as distinct from the patented valve which is for expelling materials with which the gas is miscible.
In the present case the invention contemplates the use of a valve, made in general of suitable materials such as plastics, the construction providing a tighter seal between the par-ts of the valve and the valve stem itself while at the same time the tank portion of the device is provided with a metering chamber of an improved design providing an additional compartment resulting in the trapping of gas in one compartment when material to be expelled is admitted to the chamber, and upon depression of the valve stem the trapped gas expands and pushes the material in the chamber through the stern and out to the atmosphere. In my prior patent the construction is such that there is no compressed gas entrapment.
Other objects and advantages of the invention will appear hereinafter.
Reference is to be had to the accompanying drawings in which:
FIG. 1 is a cross sectional view through the new valve, and
FIG. 2 is a sectional view on line 2-2 of FIG. 1.
In illustrating the invention there is provided a flange or skirt which forms a part of a ferrule providing means for clamping or crimping the entire device to the mouth of a container. This ferrule is shaped to the container mouth and is crimped to grasp the container at the top edge thereof as for instance at the mouth of a can or a bottle. The container mouth is indicated by the reference numeral 12 but of course these containers take many different forms.
On the rim of the container there is provided a gasket 14 solidly crimped to the container between a flange-like portion 16 of the ferrule which extends inwardly in an annular manner.
The tank flange 18 forms an integral part of the tank which is generally indicated by the reference numeral 20. This tank may be generally cylindrical and extends downwardly as at 22 forming a chamber to be further described. It turns inwardly as at 24 forming a floor for the tank having at the central portion thereof an opening at 26.
The ferrule extends upwardly from flange 16 as at 28 and again inwardly as at 30 forming a top surface having a central aperture at 32 which provides for extension of the valve stem 34 therethrough. It will be seen that the top portion of the ferrule at 30 and the floor 24 of the tank are fixed with relation to each other and form in general an enclosure.
On the floor 24 of the tank 20 there is provided a gasket 36 also having a central aperture through which the lower end of the valve 34 extends as at 38. The gasket 36 is provided in close association with the outer wall or surface of the portion 38 of the valve stem 34 and seals the same, but at the same time this portion of the valve stem is provided with grooves 40 through which gas can escape into the interior of the chamber when the stem is in the FIG. 1, or closed position.
3,3 94,85 1 Patented July 30, 1968 In the upper portion of the chamber there is provided a valve body 42 which is centrally hollow. At its lower end it is directed inwardly forming an annular shelf 44 against which a valve spring 46 finds its lowermost abutment. This spring encircles the valve stem and finds its upper abutment on a flange 48 which is fixed relative to the valve stem 34.
Inwardly of its lower portion, the valve stem is provided with an annular shoulder at 48 which reacts against another gasket 50 locked in position as will be described and this gasket forms the upper portion of a chamber in the lower portion of the tank 20. The valve stem extends through an opening in the central portion and the shoulder 48 abuts it, which determines the upper limit of motion of the valve stem.
The central portion of the valve body 42 forms a chamber with which a port at 52 is in communication through the central opening 54 of the valve stem. When the valve stem 34 is depressed against the action of spring 46, the port 52 enters the chamber in the tank 20 past gasket 50, and any material under pressure therein will therefore be expelled through the hollow central portion 54 of the valve stem to the atmosphere.
There is provided in the tank chamber a meter insert plu generally indicated by the reference numeral 56. It will be seen that this plug may be provided with projections at the top and bottom so that it is firmly anchored with respect to gaskets 36 and '50. This chamber is hollow providing openings for the valve stem so that it may operate between its uppermost and downwardmost positions, but its essential feature is that it is provided with a central generally annular bafiie which is indicated at 58. This baflle has a lower edge 60 which terminates short of the upper surface of the gasket 36 and therefore it will be seen that not only is there an inner chamber formed in the tank but there is also an auxiliary outer chamber 62 of generally cylindrical form located separate from the inner chamber but communicating therewith at the lower end thereof.
In the operation of the device with the parts as shown in FIG. 1, and assuming the use of gas under pressure such as nitrogen which does not mix wit-h the contents of the aerosol, there is of course gas in chambers 60 and 62. In order to operate the device without a dip tube, it is necessary to invert the container. Some liquid is therefore pushed into these chambers as for instance at 60 and 62 along with the gas and the gas is under pressure because the gas in the entire container is under pressure.
With the container inverted, the stem at 34 being depressed, the gas in the chamber at 62 expands because the liquid is pushed out by the gas pressure through the port 52 which is now in alignment with the chamber 60 and the chamber 60 is therefore open to the atmosphere. However there is still gas left in the chamber which is now not under pressure, and therefore pressure in the container (inverted) forces another charge of liquid and gas under pressure when the stem 34 is once more released. The port 52 is again closed with relation to chamber 60, and again chamber 60 is open with relation to the interior of the container by ports '40.
The dip tube can be applied to member 38, in which case the device will work right side up, because the liquid is forced by the gas pressure up through the dip stick from the bottom of the container through orifice 40 into chamber 60. When the stem 34 is depressed, port 52 opens to the chamber 60 and thus a charge is released. Whenever the stem 34 is depressed, the ports at 40 are closed off.
The operation is substantially the same using the dip tube with the container in upright condition or without the dip tube in inverted condition.
There may also be provided an aperture at 64 for the pressure filling of the container, this being normally closed by a downturned flange 66 which is a part of the gasket 14, and it communicates with a groove 68.
Having thus described my invention and the advantages thereof, I do not wish to be limited to the details herein disclosed, otherwise than as set forth in the claims, but what I claim is:
1. A dispensing device for controlling the discharge of a metered amount of material from a container under pressure of immiscible gas, said device comprising a tank, means to secure the tank to a container, said tank having a metering chamber therein, means in said metering chamber forming a pair of chambers, one of the latter being radially spaced from the other, a valve stem, a spring for said valve stem normally urging the same to valveclosed condition, said valve stem being retractable against the action of the valve spring to open said valve stem to the atmosphere, and means communicating between the metering chamber and the interior of the container whereby both material to be propelled and the immiscible gas are located therein, the gas being in effect trapped in the outermost of said pair of chambers, whereupon when said valve stem is retracted the gas expands and expels material in the chamber out through the valve stem.
2. The dispensing device of claim 1 wherein the means providing the chambers comprises a baffle.
3. The dispensing device of claim 1 wherein the means providing the chambers comprises a baflle, said bafile extending downwardly from the top portion of said metering chamber to a point spaced from the bottom thereof.
4. The dispensing device of claim 1 wherein the means providing the chambers comprises a bafile, said baffie extending downwardly from the top portion of said metering chamber to a point spaced from the bottom thereof and surrounding the valve stem.
5. A metering valve construction for use with immiscible materials to be expelled by gas and comprising means providing a tank, a metering chamber in the tank, an insert plug in the chamber, means holding the plug in position, a valve stem extending through the tank and the plug, said valve stem having means for admitting material under pressure out to the atmosphere when in one position thereof and when in the other position thereof closing the metering chamber to the atmosphere, and means in said insert plug providing an inner and an outer chamber dividing the metering chamber into a plurality of chambers entrapping gas in the metering chamber.
References Cited UNITED STATES PATENTS 2,693,983 11/1954 Howell 222402.2 2,721,010 10/1955 Meshberg 222402.2 2,746,796 5/1956 St. Germain 222402.2 2,856,105 10/1958 Ward 222402.2 2,995,278 8/1961 Clapp 239337 X SAMUEL F. COLEMAN, Primary Examiner.

Claims (1)

1. A DISPENSING DEVICE FOR CONTROLLING THE DISCHARGE OF A METERED AMOUNT OF MATERIAL FROM A CONTAINER UNDER PRESSURE OF IMMISCIBLE GAS, SAID DEVICE COMPRISING A TANK MEANS TO SECURE THE TANK TO A CONTAINER, SAID TANK HAVING A METERING CHAMBER THEREIN, MEANS IN SAID METERING CHAMBER FORMING A PAIR OF CHAMBERS, ONE OF THE LATTER BEING RADIALLY SPACED FROM THE OTHER, A VALVE STEM, A SPRING FOR SAID VALVE STEM NORMALLY URGING THE SAME TO VALVECLOSED CONDITION, SAID VALVE STEM BEING RETRACTABLE AGAINST THE ACTION OF THE VALVE SPRING TO OPEN SAID VALVE STEM TO THE ATMOSPHERE, AND MEANS COMMUNICATING BETWEEN THE METERING CHAMBER AND THE INTERIOR OF THE CONTAINERS WHEREBY BOTH MATERIAL TO BE PROPELLED AND THE IMMISCIBLE GAS ARE LOCATED THEREIN, THE GAS BEING IN EFFECT TRAPPED IN THE OUTERMOST OF SAID PAIR OF CHAMBERS, WHEREUPON WHEN SAID VALVE STEM IS RETRACTED THE GAS EXPANDS AND EXPELS MATERIAL IN THE CHAMBER OUT THROUGH THE VALVE STEM.
US488330A 1965-09-20 1965-09-20 Metered aerosol valve for use with compressed gas Expired - Lifetime US3394851A (en)

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Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3499584A (en) * 1966-12-21 1970-03-10 Bespak Industries Ltd Valves for pressurized dispensers
US3877618A (en) * 1974-03-25 1975-04-15 Olin Corp Lost motion fluid measuring valve assembly
US4301795A (en) * 1978-07-22 1981-11-24 Hoechst Aktiengesellschaft Vaccination gun
FR2502732A1 (en) * 1981-03-30 1982-10-01 Valois Sa REVERSE POSITIONING VALVE FOR AEROSOL CONTAINER
EP0143577A1 (en) * 1983-11-18 1985-06-05 FISONS plc Aerosol dispensing metering valve
US4842168A (en) * 1986-07-30 1989-06-27 Societe Francaise D'aerosol Et De Bouchage Dispensing valve
US4867352A (en) * 1988-04-05 1989-09-19 Philip Meshberg Dispensing valve assembly for use with a pressurized container
US5392768A (en) * 1991-03-05 1995-02-28 Aradigm Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval
US5394866A (en) * 1991-03-05 1995-03-07 Aradigm Corporation Automatic aerosol medication delivery system and methods
US5404871A (en) * 1991-03-05 1995-04-11 Aradigm Delivery of aerosol medications for inspiration
US5421492A (en) * 1993-11-02 1995-06-06 Glaxo Inc. Metered aerosol dispensing apparatus and method of use thereof
US5450336A (en) * 1991-03-05 1995-09-12 Aradigm Corporation Method for correcting the drift offset of a transducer
US5497764A (en) * 1991-03-05 1996-03-12 Aradigm Corporation Medication cassette for an automatic aerosol medication delivery
US5651477A (en) * 1994-04-01 1997-07-29 Nippon Tansan Gas Company Limited Constant quantity injection valve for liquefied carbon dioxide gas
US5697532A (en) * 1993-06-14 1997-12-16 Minnesota Mining And Manufacturing Company Metered-dose aerosol valves
US5875939A (en) * 1996-03-29 1999-03-02 Coster Tecnologie Speciali S.P.A. Valve for the discharge of fluids which are under pressure
US5921447A (en) * 1997-02-13 1999-07-13 Glaxo Wellcome Inc. Flow-through metered aerosol dispensing apparatus and method of use thereof
WO2001079079A1 (en) * 2000-04-14 2001-10-25 Presspart Manufacturing Ltd. Valve assembly for metered dose dispensers
US20020190085A1 (en) * 2000-03-07 2002-12-19 Anthony Stanford Metering valve for dispensers
US6926178B1 (en) * 1999-08-07 2005-08-09 Glaxo Group Limited Valve with a two-component seal
US20070131722A1 (en) * 2003-10-07 2007-06-14 Valois S.A.S. Valve and dispensing device comprising one such valve
US20100051653A1 (en) * 2008-08-26 2010-03-04 Miller Allen D Valve assembly for pressurized dispensers
WO2011042751A1 (en) 2009-10-09 2011-04-14 The University Of Salford Liquid dispensing apparatus
WO2011042752A1 (en) 2009-10-09 2011-04-14 The University Of Salford Liquid dispensing apparatus
AU2014202308B2 (en) * 2013-04-29 2016-04-14 Basso Industry Corp. Metering valve
WO2024033636A1 (en) 2022-08-09 2024-02-15 The Salford Valve Company Limited Metered dosage apparatus

Citations (5)

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US2693983A (en) * 1951-12-01 1954-11-09 Pharma Craft Corp Aerosol deodorant bottle
US2721010A (en) * 1954-09-20 1955-10-18 Meshberg Philip Aerosol containers and valves therefor
US2746796A (en) * 1953-08-05 1956-05-22 Pharma Craft Corp Metering valve aerosol bottle
US2856105A (en) * 1954-08-16 1958-10-14 Lawrence T Ward Spray valve
US2995278A (en) * 1959-05-22 1961-08-08 Western Filling Corp Packaged self-propelling liquid compositions

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2693983A (en) * 1951-12-01 1954-11-09 Pharma Craft Corp Aerosol deodorant bottle
US2746796A (en) * 1953-08-05 1956-05-22 Pharma Craft Corp Metering valve aerosol bottle
US2856105A (en) * 1954-08-16 1958-10-14 Lawrence T Ward Spray valve
US2721010A (en) * 1954-09-20 1955-10-18 Meshberg Philip Aerosol containers and valves therefor
US2995278A (en) * 1959-05-22 1961-08-08 Western Filling Corp Packaged self-propelling liquid compositions

Cited By (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3499584A (en) * 1966-12-21 1970-03-10 Bespak Industries Ltd Valves for pressurized dispensers
US3877618A (en) * 1974-03-25 1975-04-15 Olin Corp Lost motion fluid measuring valve assembly
US4301795A (en) * 1978-07-22 1981-11-24 Hoechst Aktiengesellschaft Vaccination gun
FR2502732A1 (en) * 1981-03-30 1982-10-01 Valois Sa REVERSE POSITIONING VALVE FOR AEROSOL CONTAINER
EP0061973A1 (en) * 1981-03-30 1982-10-06 ETABLISSEMENTS VALOIS Société Anonyme dite: Metering valve operating in inverted position, for an aerosol container
US4413755A (en) * 1981-03-30 1983-11-08 Etablissements Valois Metered aerosol valve for use in inverted position
EP0143577A1 (en) * 1983-11-18 1985-06-05 FISONS plc Aerosol dispensing metering valve
JPS60119419A (en) * 1983-11-18 1985-06-26 フアイソンズ・ピーエルシー Metering valve for dispensing aerosol
US4702400A (en) * 1983-11-18 1987-10-27 Fisons Plc Aerosol dispensing metering valve
JPH0784227B2 (en) 1983-11-18 1995-09-13 フアイソンズ・ピーエルシー Metering valve for aerosol dispensing
US4842168A (en) * 1986-07-30 1989-06-27 Societe Francaise D'aerosol Et De Bouchage Dispensing valve
USRE33552E (en) * 1986-07-30 1991-03-12 Societe Francaise D'aerosol Et De Bouchage Dispensing valve
US4867352A (en) * 1988-04-05 1989-09-19 Philip Meshberg Dispensing valve assembly for use with a pressurized container
US5622162A (en) * 1991-03-05 1997-04-22 Aradigm Corporation Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval
US5743252A (en) * 1991-03-05 1998-04-28 Aradigm Corporation Method for releasing controlled amount of aerosol medication
US5404871A (en) * 1991-03-05 1995-04-11 Aradigm Delivery of aerosol medications for inspiration
US5450336A (en) * 1991-03-05 1995-09-12 Aradigm Corporation Method for correcting the drift offset of a transducer
US5394866A (en) * 1991-03-05 1995-03-07 Aradigm Corporation Automatic aerosol medication delivery system and methods
US5497764A (en) * 1991-03-05 1996-03-12 Aradigm Corporation Medication cassette for an automatic aerosol medication delivery
US5520166A (en) * 1991-03-05 1996-05-28 Aradigm Corporation Medication cassette for an automatic aerosol medication delivery system
US5542410A (en) * 1991-03-05 1996-08-06 Aradigm Corporation Delivery of aeerosol medications for inspiration
US5608647A (en) * 1991-03-05 1997-03-04 Aradigm Corporation Method for releasing controlled amount of aerosol medication
US5392768A (en) * 1991-03-05 1995-02-28 Aradigm Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval
US5826570A (en) * 1991-03-05 1998-10-27 Aradigm Corporation Delivery of aerosol medications for inspiration
US5755218A (en) * 1991-03-05 1998-05-26 Aradigm Corporation Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval
US5697532A (en) * 1993-06-14 1997-12-16 Minnesota Mining And Manufacturing Company Metered-dose aerosol valves
US5421492A (en) * 1993-11-02 1995-06-06 Glaxo Inc. Metered aerosol dispensing apparatus and method of use thereof
US5651477A (en) * 1994-04-01 1997-07-29 Nippon Tansan Gas Company Limited Constant quantity injection valve for liquefied carbon dioxide gas
US5875939A (en) * 1996-03-29 1999-03-02 Coster Tecnologie Speciali S.P.A. Valve for the discharge of fluids which are under pressure
US5921447A (en) * 1997-02-13 1999-07-13 Glaxo Wellcome Inc. Flow-through metered aerosol dispensing apparatus and method of use thereof
US7383970B2 (en) 1999-08-07 2008-06-10 Glaxo Group Limited Valve with a two-component seal
US6926178B1 (en) * 1999-08-07 2005-08-09 Glaxo Group Limited Valve with a two-component seal
US20050269546A1 (en) * 1999-08-07 2005-12-08 Anderson Gregor J M Valve with a two-component seal
US20020190085A1 (en) * 2000-03-07 2002-12-19 Anthony Stanford Metering valve for dispensers
WO2001079079A1 (en) * 2000-04-14 2001-10-25 Presspart Manufacturing Ltd. Valve assembly for metered dose dispensers
US20070131722A1 (en) * 2003-10-07 2007-06-14 Valois S.A.S. Valve and dispensing device comprising one such valve
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US7959041B2 (en) 2008-08-26 2011-06-14 S. C. Johnson & Son, Inc. Valve assembly for pressurized dispensers
WO2011042751A1 (en) 2009-10-09 2011-04-14 The University Of Salford Liquid dispensing apparatus
WO2011042752A1 (en) 2009-10-09 2011-04-14 The University Of Salford Liquid dispensing apparatus
US20110101037A1 (en) * 2009-10-09 2011-05-05 The University Of Salford Liquid dispensing apparatus
US20110108582A1 (en) * 2009-10-09 2011-05-12 The University Of Salford Liquid dispensing apparatus
US8820589B2 (en) 2009-10-09 2014-09-02 The University Of Salford Liquid dispensing apparatus
US8820588B2 (en) 2009-10-09 2014-09-02 The University Of Salford Liquid dispensing apparatus
AU2014202308B2 (en) * 2013-04-29 2016-04-14 Basso Industry Corp. Metering valve
WO2024033636A1 (en) 2022-08-09 2024-02-15 The Salford Valve Company Limited Metered dosage apparatus

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